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The map label for this gene is Ag36

Identifier: 221230765

GI number: 221230765

Start: 2864935

End: 2865684

Strand: Reverse

Name: Ag36

Synonym: MLBr_02395

Alternate gene names: 221230765

Gene position: 2865684-2864935 (Counterclockwise)

Preceding gene: 221230766

Following gene: 221230764

Centisome position: 87.69

GC content: 62.53

Gene sequence:

>750_bases
ATGACCGATCAACCGCCGCCGAGCGGGTCTAACCCGACACCTGCTCCGCCCCCGCCCGGGTCATCCGGTGGGTATGAGCC
TTCGTTTGCCCCGTCTGAGCTGGGCTCTGCCTACCCGCCGCCTACTGCGCCACCCGTCGGTGGTTCTTACCCGCCACCTC
CGCCGCCCGGCGGTTCTTACCCGCCACCTCCGCCGCCCGGCGGTTCTTACCCGCCACCTCCGCCTTCCACCGGCGCGTAC
GCGCCGCCTCCACCTGGACCGGCGATCCGCTCACTGCCTAAGGAGGCCTACACATTCTGGGTCACCCGGGTGCTGGCTTA
TGTCATCGACAACATCCCAGCCACGGTCCTGCTCGGCATTGGCATGTTGATTCAGACGCTCACGAAGCAAGAGGCGTGCG
TCACTGATATCACGCAGTACAATGTTAATCAGTACTGTGCTACTCAGCCTACCGGCATCGGCATGTTGGCGTTCTGGTTC
GCATGGTTGATGGCGACGGCCTACCTGGTCTGGAACTACGGCTATCGCCAGGGCGCCACCGGCTCCAGCATTGGCAAGAC
GGTAATGAAGTTCAAGGTGATCAGCGAGGCTACTGGGCAGCCAATCGGTTTCGGTATGTCGGTGGTGCGCCAGCTCGCGC
ACTTCGTCGATGCGGTCATCTGTTGCATCGGGTTCTTGTTCCCGCTGTGGGACTCCAAACGGCAAACCCTGGCGGACAAG
ATCATGACGACGGTGTGTCTGCCGATCTGA

Upstream 100 bases:

>100_bases
CGACTCGATACGCCGAAACCCGTGCCCGTTCGCTACGCGAATTTGTTCTCAGGTAGGGTAATGCGGCCTAGTTCAGCTCC
TCCGCAGTGGAAGGTTACCC

Downstream 100 bases:

>100_bases
CACAGTGCCACGACTTGGCAGGCTAGTCGGCGGCCCCCCAACCGCTGACCGCAGCGGCCATCTCTTAGGCTAATCGTCGA
TGAGCGAAGATTACCGGGGA

Product: proline rich antigenic protein

Products: NA

Alternate protein names: 36 kDa antigen

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MTDQPPPSGSNPTPAPPPPGSSGGYEPSFAPSELGSAYPPPTAPPVGGSYPPPPPPGGSYPPPPPPGGSYPPPPPSTGAY
APPPPGPAIRSLPKEAYTFWVTRVLAYVIDNIPATVLLGIGMLIQTLTKQEACVTDITQYNVNQYCATQPTGIGMLAFWF
AWLMATAYLVWNYGYRQGATGSSIGKTVMKFKVISEATGQPIGFGMSVVRQLAHFVDAVICCIGFLFPLWDSKRQTLADK
IMTTVCLPI

Sequences:

>Translated_249_residues
MTDQPPPSGSNPTPAPPPPGSSGGYEPSFAPSELGSAYPPPTAPPVGGSYPPPPPPGGSYPPPPPPGGSYPPPPPSTGAY
APPPPGPAIRSLPKEAYTFWVTRVLAYVIDNIPATVLLGIGMLIQTLTKQEACVTDITQYNVNQYCATQPTGIGMLAFWF
AWLMATAYLVWNYGYRQGATGSSIGKTVMKFKVISEATGQPIGFGMSVVRQLAHFVDAVICCIGFLFPLWDSKRQTLADK
IMTTVCLPI
>Mature_248_residues
TDQPPPSGSNPTPAPPPPGSSGGYEPSFAPSELGSAYPPPTAPPVGGSYPPPPPPGGSYPPPPPPGGSYPPPPPSTGAYA
PPPPGPAIRSLPKEAYTFWVTRVLAYVIDNIPATVLLGIGMLIQTLTKQEACVTDITQYNVNQYCATQPTGIGMLAFWFA
WLMATAYLVWNYGYRQGATGSSIGKTVMKFKVISEATGQPIGFGMSVVRQLAHFVDAVICCIGFLFPLWDSKRQTLADKI
MTTVCLPI

Specific function: Unknown

COG id: COG1714

COG function: function code S; Predicted membrane protein/domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.tuberculosis PRA homolog

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRA_MYCLE (P41484)

Other databases:

- EMBL:   X65546
- EMBL:   U15183
- EMBL:   AL583925
- PIR:   A41497
- RefSeq:   NP_302551.1
- ProteinModelPortal:   P41484
- EnsemblBacteria:   EBMYCT00000028789
- GeneID:   908610
- GenomeReviews:   AL450380_GR
- KEGG:   mle:ML2395
- NMPDR:   fig|272631.1.peg.1423
- Leproma:   ML2395
- GeneTree:   EBGT00050000014860
- HOGENOM:   HBG751082
- OMA:   MKFKVVS
- ProtClustDB:   CLSK790936
- BioCyc:   MLEP272631:ML2395-MONOMER
- InterPro:   IPR010432

Pfam domain/function: PF06271 RDD

EC number: NA

Molecular weight: Translated: 26295; Mature: 26164

Theoretical pI: Translated: 7.80; Mature: 7.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDQPPPSGSNPTPAPPPPGSSGGYEPSFAPSELGSAYPPPTAPPVGGSYPPPPPPGGSY
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
PPPPPPGGSYPPPPPSTGAYAPPPPGPAIRSLPKEAYTFWVTRVLAYVIDNIPATVLLGI
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
GMLIQTLTKQEACVTDITQYNVNQYCATQPTGIGMLAFWFAWLMATAYLVWNYGYRQGAT
HHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GSSIGKTVMKFKVISEATGQPIGFGMSVVRQLAHFVDAVICCIGFLFPLWDSKRQTLADK
CHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
IMTTVCLPI
HHHHHHCCC
>Mature Secondary Structure 
TDQPPPSGSNPTPAPPPPGSSGGYEPSFAPSELGSAYPPPTAPPVGGSYPPPPPPGGSY
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
PPPPPPGGSYPPPPPSTGAYAPPPPGPAIRSLPKEAYTFWVTRVLAYVIDNIPATVLLGI
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
GMLIQTLTKQEACVTDITQYNVNQYCATQPTGIGMLAFWFAWLMATAYLVWNYGYRQGAT
HHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GSSIGKTVMKFKVISEATGQPIGFGMSVVRQLAHFVDAVICCIGFLFPLWDSKRQTLADK
CHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
IMTTVCLPI
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1688422; 11234002