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The map label for this gene is cmk

Identifier: 221230193

GI number: 221230193

Start: 1631138

End: 1631809

Strand: Direct

Name: cmk

Synonym: MLBr_01371

Alternate gene names: 221230193

Gene position: 1631138-1631809 (Clockwise)

Preceding gene: 221230192

Following gene: 221230194

Centisome position: 49.91

GC content: 59.82

Gene sequence:

>672_bases
GTGACCGATATTGTTGTCGCCATCGACGGACCGGCGGGGACCGGAAAATCTTCCGTGTCAAGGGGACTAGCGCGTGAGCT
GGGGGCGCGCTACTTAGATACCGGGGCAATGTACCGTATGATGACATTGGCGGTGCTGCGCGCCGGAATTGATCCAGCAG
ATGCTGCAGCGATTGGGGAGAGTGTTTGGAAAGTGCAGATGCTCTCCGATCATGATCGTTATTTCCTTGGTGGAGAGGAT
GTTTCATCTGAGATACGGACTGAGGAGGTCACCCAGGCGGTGTCGGCGGTGTCGGCGATTCCTGCCGTGCGCGTCCGGCT
TGTTGATCTGCAGCGACAGATGGCCGAAGGGCGAGGCAGTGTCGTTGTAGAGGGCCGCGATATTGGGACCGTTGTATTAC
CCGACGCTCCGGTGAAGATCTTTCTGACGGCATCGCCCGAAACCCGCGCGCGACGTCGCAACGACCAGAATGTCGCGTCA
GGTTCGGCCGACGATTATGACCGCGTGTTGGCCGAAGTGCGCCGCCGCGACCATCTCGACTCCACCCGGGCGGTGTCGCC
GTTGTATGTGGCTCAAGACGCCATGATTGTTGACACCAGCAAGATGGCTGAAGCCGAGGTGATCGCCCACCTAATGGACT
TGGTGAAGCAGCGCAGTGGGGCGGTGTGGTGA

Upstream 100 bases:

>100_bases
GCACCGATATCGGTGCGGTGTCGCTGGGAGATCAGCGTCCGGGCTGCCTTCGGGCTTTGCTCCGTGATGAGATCAGACAA
CTGTATAAAGAGGTGGGCCT

Downstream 100 bases:

>100_bases
GCCAGGATGGCACCTGGAGTGACGAAAGCGACTGGGAACTTGACGATTCGGATCTAGCCGAGTTCGGGCCGGTGGTGGCG
GTGGTGGGCAGGCCTAATGT

Product: cytidylate kinase

Products: NA

Alternate protein names: CK; Cytidine monophosphate kinase; CMP kinase

Number of amino acids: Translated: 223; Mature: 222

Protein sequence:

>223_residues
MTDIVVAIDGPAGTGKSSVSRGLARELGARYLDTGAMYRMMTLAVLRAGIDPADAAAIGESVWKVQMLSDHDRYFLGGED
VSSEIRTEEVTQAVSAVSAIPAVRVRLVDLQRQMAEGRGSVVVEGRDIGTVVLPDAPVKIFLTASPETRARRRNDQNVAS
GSADDYDRVLAEVRRRDHLDSTRAVSPLYVAQDAMIVDTSKMAEAEVIAHLMDLVKQRSGAVW

Sequences:

>Translated_223_residues
MTDIVVAIDGPAGTGKSSVSRGLARELGARYLDTGAMYRMMTLAVLRAGIDPADAAAIGESVWKVQMLSDHDRYFLGGED
VSSEIRTEEVTQAVSAVSAIPAVRVRLVDLQRQMAEGRGSVVVEGRDIGTVVLPDAPVKIFLTASPETRARRRNDQNVAS
GSADDYDRVLAEVRRRDHLDSTRAVSPLYVAQDAMIVDTSKMAEAEVIAHLMDLVKQRSGAVW
>Mature_222_residues
TDIVVAIDGPAGTGKSSVSRGLARELGARYLDTGAMYRMMTLAVLRAGIDPADAAAIGESVWKVQMLSDHDRYFLGGEDV
SSEIRTEEVTQAVSAVSAIPAVRVRLVDLQRQMAEGRGSVVVEGRDIGTVVLPDAPVKIFLTASPETRARRRNDQNVASG
SADDYDRVLAEVRRRDHLDSTRAVSPLYVAQDAMIVDTSKMAEAEVIAHLMDLVKQRSGAVW

Specific function: ATP, Datp, And GTP Are Equally Effective As Phosphate Donors. CMP And Dcmp Are The Best Phosphate Acceptors. [C]

COG id: COG0283

COG function: function code F; Cytidylate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidylate kinase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1787139, Length=224, Percent_Identity=43.3035714285714, Blast_Score=159, Evalue=1e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KCY_MYCLB (B8ZRI2)

Other databases:

- EMBL:   FM211192
- RefSeq:   YP_002503609.1
- ProteinModelPortal:   B8ZRI2
- SMR:   B8ZRI2
- EnsemblBacteria:   EBMYCT00000085080
- GeneID:   7326510
- GenomeReviews:   FM211192_GR
- GeneTree:   EBGT00050000015811
- HOGENOM:   HBG354377
- OMA:   DIGTVIC
- ProtClustDB:   PRK00023
- GO:   GO:0005737
- HAMAP:   MF_00238
- InterPro:   IPR003136
- InterPro:   IPR011994
- PANTHER:   PTHR21299:SF2
- TIGRFAMs:   TIGR00017

Pfam domain/function: PF02224 Cytidylate_kin

EC number: =2.7.4.14

Molecular weight: Translated: 24111; Mature: 23979

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDIVVAIDGPAGTGKSSVSRGLARELGARYLDTGAMYRMMTLAVLRAGIDPADAAAIGE
CCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
SVWKVQMLSDHDRYFLGGEDVSSEIRTEEVTQAVSAVSAIPAVRVRLVDLQRQMAEGRGS
HHHEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VVVEGRDIGTVVLPDAPVKIFLTASPETRARRRNDQNVASGSADDYDRVLAEVRRRDHLD
EEEECCCCCEEEECCCCEEEEEECCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCC
STRAVSPLYVAQDAMIVDTSKMAEAEVIAHLMDLVKQRSGAVW
HHHCCCCCEEECCEEEECHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TDIVVAIDGPAGTGKSSVSRGLARELGARYLDTGAMYRMMTLAVLRAGIDPADAAAIGE
CEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
SVWKVQMLSDHDRYFLGGEDVSSEIRTEEVTQAVSAVSAIPAVRVRLVDLQRQMAEGRGS
HHHEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VVVEGRDIGTVVLPDAPVKIFLTASPETRARRRNDQNVASGSADDYDRVLAEVRRRDHLD
EEEECCCCCEEEECCCCEEEEEECCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCC
STRAVSPLYVAQDAMIVDTSKMAEAEVIAHLMDLVKQRSGAVW
HHHCCCCCEEECCEEEECHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA