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The map label for this gene is engA [H]

Identifier: 221230194

GI number: 221230194

Start: 1631803

End: 1633191

Strand: Direct

Name: engA [H]

Synonym: MLBr_01372

Alternate gene names: 221230194

Gene position: 1631803-1633191 (Clockwise)

Preceding gene: 221230193

Following gene: 221230195

Centisome position: 49.93

GC content: 61.2

Gene sequence:

>1389_bases
GTGGTGAGCCAGGATGGCACCTGGAGTGACGAAAGCGACTGGGAACTTGACGATTCGGATCTAGCCGAGTTCGGGCCGGT
GGTGGCGGTGGTGGGCAGGCCTAATGTCGGCAAATCGACGTTGGTTAACCGAATTCTGGGCCGGCGCGAAGCGGTGGTGC
AGGATGTTCCCGGGGTGACTCGCGACCGAGTCTCCTATGATGCAATGTGGACCGGACGTCGGTTCGTCGTACAGGACACC
GGAGGATGGGAACCCGACGCCAAAGGCCTCAAACGGCTGGTGGCGGAGCAGGCGTCGGTGGCCATGCGCACCGCCGACGC
GGTGATCCTTGTGGTTGACGTCGGTGTCGGGGCCACTGACGCCGACGAAGCCGCAGCTCGGATTTTGCTCCGCTCGGGTA
AGCTGGTATTCTTAGCAGCCAACAAGGTGGACGGCGAAAAGGGCGAATCGGACGCGTCGGCATTGTGGTCGCTGGGACTG
GGTGAGCCGCACGCAATCAGTGCGATGCATGGTCGCGGCGTAGCTGACCTGCTTGACAAGGTGCTGGCCGCACTGCCCAA
CGTGGCTGAATCGACGTCGCTTGACGGCGGTCTTCGGCGTGTGGCGCTCGTCGGCAAGCCCAATGTGGGCAAGAGTTCAT
TGCTGAACAAGTTGGCAGGTGACCAGCGTTCGGTAGTCCACGAGGCCGCAGGGACGACAGTAGACCCTGTGGACTCACTT
ATTGAAATGGGCGGCAGGGTCTGGCGTTTCGTCGACACCGCGGGTTTGCGTCGAAAAGTCGGTCAGGCAAGCGGGCACGA
ATTCTATGCTTCGGTGCGCACTCATGGGGCCATCGATTCGGCCGAAGTGGTGATCATGCTGATCGACGCATCGGAGCCGC
TAACGGGACAAGATCAGCGGGTGCTCTCTATGGTTATCGATGCTGGTCGCGCGTTGGTGCTGGCCTTCAATAAGTGGGAT
CTAGTTGACGAAGATCGGTGCGATCTGCTGGAGCGCGAGATCGATCGTGAGCTGGTGCAGGTGCGTTGGGCGCAACGGGT
CAATATCTCCGCCAAGACGGGCCGGGCGGTGCAGAAACTGGTGCCGGCGATGGAAAATTCGCTGGCGTCGTGGGATACCA
GAATTGCGACCGGCCCGCTGAACATATGGATTAAGGCAGTGGTGGCGGCGACACCACCCCCGGTGCGCGGTGGCAAGCAG
CCGCGCATACTATTCGCTACCCAGGCGACTGCTCGACCGCCGACGTTCGTGCTGTTCACGACTGGTTTTCTGGAAGCCTG
CTACCGACGCTTCCTAGAACGTCGGCTACGTGAGACGTTTGGGTTTGAGGGCAGTCCGATCCGGATCAATGTGCGAGTGC
GCGAAAAACGGGGACTCAAGCGCCGCTAA

Upstream 100 bases:

>100_bases
ATGTGGCTCAAGACGCCATGATTGTTGACACCAGCAAGATGGCTGAAGCCGAGGTGATCGCCCACCTAATGGACTTGGTG
AAGCAGCGCAGTGGGGCGGT

Downstream 100 bases:

>100_bases
CTGTGTTGCATCGTCGCTAGGCTGAGCCGTCATCCGGAAGTTAGTGCTCCGGATGGTGAAAGTCGTTGTTATCATATACC
ATTGGTGATCATGGAGAAGA

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MVSQDGTWSDESDWELDDSDLAEFGPVVAVVGRPNVGKSTLVNRILGRREAVVQDVPGVTRDRVSYDAMWTGRRFVVQDT
GGWEPDAKGLKRLVAEQASVAMRTADAVILVVDVGVGATDADEAAARILLRSGKLVFLAANKVDGEKGESDASALWSLGL
GEPHAISAMHGRGVADLLDKVLAALPNVAESTSLDGGLRRVALVGKPNVGKSSLLNKLAGDQRSVVHEAAGTTVDPVDSL
IEMGGRVWRFVDTAGLRRKVGQASGHEFYASVRTHGAIDSAEVVIMLIDASEPLTGQDQRVLSMVIDAGRALVLAFNKWD
LVDEDRCDLLEREIDRELVQVRWAQRVNISAKTGRAVQKLVPAMENSLASWDTRIATGPLNIWIKAVVAATPPPVRGGKQ
PRILFATQATARPPTFVLFTTGFLEACYRRFLERRLRETFGFEGSPIRINVRVREKRGLKRR

Sequences:

>Translated_462_residues
MVSQDGTWSDESDWELDDSDLAEFGPVVAVVGRPNVGKSTLVNRILGRREAVVQDVPGVTRDRVSYDAMWTGRRFVVQDT
GGWEPDAKGLKRLVAEQASVAMRTADAVILVVDVGVGATDADEAAARILLRSGKLVFLAANKVDGEKGESDASALWSLGL
GEPHAISAMHGRGVADLLDKVLAALPNVAESTSLDGGLRRVALVGKPNVGKSSLLNKLAGDQRSVVHEAAGTTVDPVDSL
IEMGGRVWRFVDTAGLRRKVGQASGHEFYASVRTHGAIDSAEVVIMLIDASEPLTGQDQRVLSMVIDAGRALVLAFNKWD
LVDEDRCDLLEREIDRELVQVRWAQRVNISAKTGRAVQKLVPAMENSLASWDTRIATGPLNIWIKAVVAATPPPVRGGKQ
PRILFATQATARPPTFVLFTTGFLEACYRRFLERRLRETFGFEGSPIRINVRVREKRGLKRR
>Mature_462_residues
MVSQDGTWSDESDWELDDSDLAEFGPVVAVVGRPNVGKSTLVNRILGRREAVVQDVPGVTRDRVSYDAMWTGRRFVVQDT
GGWEPDAKGLKRLVAEQASVAMRTADAVILVVDVGVGATDADEAAARILLRSGKLVFLAANKVDGEKGESDASALWSLGL
GEPHAISAMHGRGVADLLDKVLAALPNVAESTSLDGGLRRVALVGKPNVGKSSLLNKLAGDQRSVVHEAAGTTVDPVDSL
IEMGGRVWRFVDTAGLRRKVGQASGHEFYASVRTHGAIDSAEVVIMLIDASEPLTGQDQRVLSMVIDAGRALVLAFNKWD
LVDEDRCDLLEREIDRELVQVRWAQRVNISAKTGRAVQKLVPAMENSLASWDTRIATGPLNIWIKAVVAATPPPVRGGKQ
PRILFATQATARPPTFVLFTTGFLEACYRRFLERRLRETFGFEGSPIRINVRVREKRGLKRR

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=456, Percent_Identity=35.0877192982456, Blast_Score=257, Evalue=1e-69,
Organism=Escherichia coli, GI1788919, Length=168, Percent_Identity=31.547619047619, Blast_Score=63, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17507259, Length=127, Percent_Identity=33.8582677165354, Blast_Score=65, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6323665, Length=206, Percent_Identity=27.1844660194175, Blast_Score=76, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 50240; Mature: 50240

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSQDGTWSDESDWELDDSDLAEFGPVVAVVGRPNVGKSTLVNRILGRREAVVQDVPGVT
CCCCCCCCCCCCCCCCCCHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCC
RDRVSYDAMWTGRRFVVQDTGGWEPDAKGLKRLVAEQASVAMRTADAVILVVDVGVGATD
HHCCCCCEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCC
ADEAAARILLRSGKLVFLAANKVDGEKGESDASALWSLGLGEPHAISAMHGRGVADLLDK
HHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHCCCCCCCEEHHHCCCCHHHHHHH
VLAALPNVAESTSLDGGLRRVALVGKPNVGKSSLLNKLAGDQRSVVHEAAGTTVDPVDSL
HHHHCCCCHHHCCCCCCCEEEEEECCCCCCHHHHHHHHCCCHHHHHHHHCCCCCCHHHHH
IEMGGRVWRFVDTAGLRRKVGQASGHEFYASVRTHGAIDSAEVVIMLIDASEPLTGQDQR
HHCCCCEEEHHHHHHHHHHHCCCCCCHHEEHHHHCCCCCCCCEEEEEEECCCCCCCCHHH
VLSMVIDAGRALVLAFNKWDLVDEDRCDLLEREIDRELVQVRWAQRVNISAKTGRAVQKL
HHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
VPAMENSLASWDTRIATGPLNIWIKAVVAATPPPVRGGKQPRILFATQATARPPTFVLFT
HHHHHHHHHHCCCEEECCHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCEEEEEH
TGFLEACYRRFLERRLRETFGFEGSPIRINVRVREKRGLKRR
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHCCCCCCC
>Mature Secondary Structure
MVSQDGTWSDESDWELDDSDLAEFGPVVAVVGRPNVGKSTLVNRILGRREAVVQDVPGVT
CCCCCCCCCCCCCCCCCCHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCC
RDRVSYDAMWTGRRFVVQDTGGWEPDAKGLKRLVAEQASVAMRTADAVILVVDVGVGATD
HHCCCCCEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCC
ADEAAARILLRSGKLVFLAANKVDGEKGESDASALWSLGLGEPHAISAMHGRGVADLLDK
HHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHCCCCCCCEEHHHCCCCHHHHHHH
VLAALPNVAESTSLDGGLRRVALVGKPNVGKSSLLNKLAGDQRSVVHEAAGTTVDPVDSL
HHHHCCCCHHHCCCCCCCEEEEEECCCCCCHHHHHHHHCCCHHHHHHHHCCCCCCHHHHH
IEMGGRVWRFVDTAGLRRKVGQASGHEFYASVRTHGAIDSAEVVIMLIDASEPLTGQDQR
HHCCCCEEEHHHHHHHHHHHCCCCCCHHEEHHHHCCCCCCCCEEEEEEECCCCCCCCHHH
VLSMVIDAGRALVLAFNKWDLVDEDRCDLLEREIDRELVQVRWAQRVNISAKTGRAVQKL
HHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
VPAMENSLASWDTRIATGPLNIWIKAVVAATPPPVRGGKQPRILFATQATARPPTFVLFT
HHHHHHHHHHCCCEEECCHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCEEEEEH
TGFLEACYRRFLERRLRETFGFEGSPIRINVRVREKRGLKRR
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]