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The map label for this gene is hflX [H]

Identifier: 221229953

GI number: 221229953

Start: 1165310

End: 1166776

Strand: Direct

Name: hflX [H]

Synonym: MLBr_00997

Alternate gene names: 221229953

Gene position: 1165310-1166776 (Clockwise)

Preceding gene: 221229952

Following gene: 221229955

Centisome position: 35.66

GC content: 61.76

Gene sequence:

>1467_bases
ATGAAATATCCAGATTCGTCCGATAGGGGCTCTGCAGACTTTCCGGATCTCTGGGACTCGTCAGACTCGGTGCCTAGCAC
CGGTGAGCTTGCCCTTCATGACCGATTGGCGCTGCGCCGGATTGCCGGGCTGTCCACCGAACTCGCTGATGTTTCCGAGG
TCGAGTACCGCCAACTGCGGCTGGAACGGGTGGTGTTGGTTGGTGTGTGGACCGAGGGCAGCGCGGCCGACAATCAGGCC
AGCATGGCCGAACTTGCGACCCTGGCCGAAACCGCCGGTTCGCAGGTTCTCGAAGGTCTCATCCAACGTCGCGATCGGCC
CGATCCGTCGACCTACATCGGTTCTGGCAAGGCGGCTGAATTGCGTGAGGTGGTGCTGGCCACCGGCGCCGACACCGTCA
TCTGCGACGGTGAACTGTCCCCTGCGCAGTTGACCGCGCTGGAGAAGGCGGTCAAGGTGAAGGTCATCGACCGCACCGCG
CTGATCCTTGACATTTTTGCTCAGCACGCGACCAGCCGGGAAGGCAAAGCCCAGGTGTTGTTGGCTCAGATGGCTTATAT
GCTACCGCGGCTACGCGGCTGGGGTGAGTCGATGTCACGTCAGGTTGGTGGTCGAGCCGGTGGCAGTGGCGGAGGAGTGG
GCTTGCGAGGTCCCGGTGAGACCAAAATTGAGACCGACCGACGTAGAATCCGGGAACGGATGGCCAAGCTGCGTCGGGAT
ATCGGCGCTATGAAGCAGGCCCGCGACACCCAGCGCAGCCGCCGGTTGCACAGCGACATTCCGTCGATCGCTATCGTCGG
CTATACCAATGCCGGCAAGTCCAGTGTGCTGAATGCGCTGACCGGGGCGTGGGTGCTAGTGCAGGACGCGTTGTTCGTCA
CCCTAGAACCCACCACCCGGCACGCAGAATTCGATAACGGTCAGCCGTTCGTGTTCACCGACACCGTGGGGTTCGTTCGC
CATCTGCCTACTCAGCTGGTCGAAGCATTCCGTTCCACACTGGAGGAGGTCGTTGACGCCGACCTGTTATTGCATGTCGT
CGACGGCTCAGATGCCAACCCGTTGGCTCAGATCAATGCTGTCCGTCAGGTGATCTTTGAGGTTATTTCCGATCACCAGG
ACGGTGGCGTGGAGGTGCCGCATGAGCTGTTGGTGGTCAACAAGATCGACGCCGCAAGCGCTCTGATGTTGGCCAAGCTT
CGTCACGGGTTGCCAGGCGCCGTGTTCATCTCCGCTCGCACCGGGGACGGTATCGACGTGTTGCGGCGACGGATAGCCGA
GCTCGTTGTGGCCACCGACACCGCTGTAGACGTGGTGATCCCGTACGACCGTGGTGATCTGGTGGCTCGCCTGCACGCTA
ACGGGCGCGTTCAGCAGGCAGAGCACAATTCGAACGGCACCCGGATCAAGGCCCGGGTTCCCGTGGCGTTGGCCGCCTGC
TTACAGGAGTTTTCGGCCGACCGATAG

Upstream 100 bases:

>100_bases
CGGACGCCTGGTGGTACTCGTTGGCGCGCAGCTGTTAAATGTTGCGGGAATTTATTCGGATGCGCGCCCAGCTACGAAGT
GCCACCATCGGATACTGGCT

Downstream 100 bases:

>100_bases
CTGTTGCCGGTCAGATGTCACCGGGTTCTTCATCCCCGCCGGTACGCGACGCATCGCTTGGTTAGCCAGTTGGTGGGTCG
GGCGGCAAGTTGTTGACCAA

Product: putative ATP/GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 488; Mature: 488

Protein sequence:

>488_residues
MKYPDSSDRGSADFPDLWDSSDSVPSTGELALHDRLALRRIAGLSTELADVSEVEYRQLRLERVVLVGVWTEGSAADNQA
SMAELATLAETAGSQVLEGLIQRRDRPDPSTYIGSGKAAELREVVLATGADTVICDGELSPAQLTALEKAVKVKVIDRTA
LILDIFAQHATSREGKAQVLLAQMAYMLPRLRGWGESMSRQVGGRAGGSGGGVGLRGPGETKIETDRRRIRERMAKLRRD
IGAMKQARDTQRSRRLHSDIPSIAIVGYTNAGKSSVLNALTGAWVLVQDALFVTLEPTTRHAEFDNGQPFVFTDTVGFVR
HLPTQLVEAFRSTLEEVVDADLLLHVVDGSDANPLAQINAVRQVIFEVISDHQDGGVEVPHELLVVNKIDAASALMLAKL
RHGLPGAVFISARTGDGIDVLRRRIAELVVATDTAVDVVIPYDRGDLVARLHANGRVQQAEHNSNGTRIKARVPVALAAC
LQEFSADR

Sequences:

>Translated_488_residues
MKYPDSSDRGSADFPDLWDSSDSVPSTGELALHDRLALRRIAGLSTELADVSEVEYRQLRLERVVLVGVWTEGSAADNQA
SMAELATLAETAGSQVLEGLIQRRDRPDPSTYIGSGKAAELREVVLATGADTVICDGELSPAQLTALEKAVKVKVIDRTA
LILDIFAQHATSREGKAQVLLAQMAYMLPRLRGWGESMSRQVGGRAGGSGGGVGLRGPGETKIETDRRRIRERMAKLRRD
IGAMKQARDTQRSRRLHSDIPSIAIVGYTNAGKSSVLNALTGAWVLVQDALFVTLEPTTRHAEFDNGQPFVFTDTVGFVR
HLPTQLVEAFRSTLEEVVDADLLLHVVDGSDANPLAQINAVRQVIFEVISDHQDGGVEVPHELLVVNKIDAASALMLAKL
RHGLPGAVFISARTGDGIDVLRRRIAELVVATDTAVDVVIPYDRGDLVARLHANGRVQQAEHNSNGTRIKARVPVALAAC
LQEFSADR
>Mature_488_residues
MKYPDSSDRGSADFPDLWDSSDSVPSTGELALHDRLALRRIAGLSTELADVSEVEYRQLRLERVVLVGVWTEGSAADNQA
SMAELATLAETAGSQVLEGLIQRRDRPDPSTYIGSGKAAELREVVLATGADTVICDGELSPAQLTALEKAVKVKVIDRTA
LILDIFAQHATSREGKAQVLLAQMAYMLPRLRGWGESMSRQVGGRAGGSGGGVGLRGPGETKIETDRRRIRERMAKLRRD
IGAMKQARDTQRSRRLHSDIPSIAIVGYTNAGKSSVLNALTGAWVLVQDALFVTLEPTTRHAEFDNGQPFVFTDTVGFVR
HLPTQLVEAFRSTLEEVVDADLLLHVVDGSDANPLAQINAVRQVIFEVISDHQDGGVEVPHELLVVNKIDAASALMLAKL
RHGLPGAVFISARTGDGIDVLRRRIAELVVATDTAVDVVIPYDRGDLVARLHANGRVQQAEHNSNGTRIKARVPVALAAC
LQEFSADR

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310124269, Length=212, Percent_Identity=33.4905660377358, Blast_Score=109, Evalue=7e-24,
Organism=Homo sapiens, GI310124267, Length=212, Percent_Identity=33.4905660377358, Blast_Score=109, Evalue=7e-24,
Organism=Homo sapiens, GI310124171, Length=212, Percent_Identity=33.4905660377358, Blast_Score=109, Evalue=7e-24,
Organism=Homo sapiens, GI310124169, Length=212, Percent_Identity=33.4905660377358, Blast_Score=109, Evalue=7e-24,
Organism=Homo sapiens, GI310133118, Length=220, Percent_Identity=33.6363636363636, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI310133116, Length=220, Percent_Identity=33.6363636363636, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI1790615, Length=418, Percent_Identity=38.755980861244, Blast_Score=263, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI17561038, Length=297, Percent_Identity=32.6599326599327, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24650079, Length=301, Percent_Identity=32.2259136212625, Blast_Score=117, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 52802; Mature: 52802

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYPDSSDRGSADFPDLWDSSDSVPSTGELALHDRLALRRIAGLSTELADVSEVEYRQLR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LERVVLVGVWTEGSAADNQASMAELATLAETAGSQVLEGLIQRRDRPDPSTYIGSGKAAE
HEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHH
LREVVLATGADTVICDGELSPAQLTALEKAVKVKVIDRTALILDIFAQHATSREGKAQVL
HHHHHHHCCCCEEEECCCCCHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHCCCCCHHHHH
LAQMAYMLPRLRGWGESMSRQVGGRAGGSGGGVGLRGPGETKIETDRRRIRERMAKLRRD
HHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
IGAMKQARDTQRSRRLHSDIPSIAIVGYTNAGKSSVLNALTGAWVLVQDALFVTLEPTTR
HHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHEEECEEEEEECCCCC
HAEFDNGQPFVFTDTVGFVRHLPTQLVEAFRSTLEEVVDADLLLHVVDGSDANPLAQINA
CCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEEEECCCCCCHHHHHHH
VRQVIFEVISDHQDGGVEVPHELLVVNKIDAASALMLAKLRHGLPGAVFISARTGDGIDV
HHHHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCCCCHHH
LRRRIAELVVATDTAVDVVIPYDRGDLVARLHANGRVQQAEHNSNGTRIKARVPVALAAC
HHHHHHHHHHCCCCEEEEEEECCCCCEEEEECCCCCEEECCCCCCCCEEEEECCHHHHHH
LQEFSADR
HHHHCCCC
>Mature Secondary Structure
MKYPDSSDRGSADFPDLWDSSDSVPSTGELALHDRLALRRIAGLSTELADVSEVEYRQLR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LERVVLVGVWTEGSAADNQASMAELATLAETAGSQVLEGLIQRRDRPDPSTYIGSGKAAE
HEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHH
LREVVLATGADTVICDGELSPAQLTALEKAVKVKVIDRTALILDIFAQHATSREGKAQVL
HHHHHHHCCCCEEEECCCCCHHHHHHHHHHHEEEEEHHHHHHHHHHHHHHCCCCCHHHHH
LAQMAYMLPRLRGWGESMSRQVGGRAGGSGGGVGLRGPGETKIETDRRRIRERMAKLRRD
HHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
IGAMKQARDTQRSRRLHSDIPSIAIVGYTNAGKSSVLNALTGAWVLVQDALFVTLEPTTR
HHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHEEECEEEEEECCCCC
HAEFDNGQPFVFTDTVGFVRHLPTQLVEAFRSTLEEVVDADLLLHVVDGSDANPLAQINA
CCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEEEECCCCCCHHHHHHH
VRQVIFEVISDHQDGGVEVPHELLVVNKIDAASALMLAKLRHGLPGAVFISARTGDGIDV
HHHHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCCCCHHH
LRRRIAELVVATDTAVDVVIPYDRGDLVARLHANGRVQQAEHNSNGTRIKARVPVALAAC
HHHHHHHHHHCCCCEEEEEEECCCCCEEEEECCCCCEEECCCCCCCCEEEEECCHHHHHH
LQEFSADR
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]