Click here to switch to the map view.

The map label for this gene is 221229624

Identifier: 221229624

GI number: 221229624

Start: 555058

End: 555678

Strand: Reverse

Name: 221229624

Synonym: MLBr_00455

Alternate gene names: NA

Gene position: 555678-555058 (Counterclockwise)

Preceding gene: 221229625

Following gene: 221229623

Centisome position: 17.0

GC content: 59.42

Gene sequence:

>621_bases
GTGAGTGAGCAGGAAAGACCCGACACACGTGCCGATCACACAGACGGCACCATCTTGGACATGGGCGTCGGCGAGCGCGA
CCACTTGCAACGGCTGTGGACACCGTACCGGATGACCTATCTGGCTGAAGCGCCAGTCAATCACGACAACTCCACCCCGG
CGCAGCCGTTCACCGACATTCCACAATTGTCCGATGAAGACGGCTTGGTGGTAGCCCGCGGTGAACTCGTCTACGCCGTG
CTCAACCTCTACCCGTACAACCCCGGGCACCTAATGGTGGTGCCCTACCGGCAAGTTTCCGAGCTTGAAGACCTAACCGA
CGCAGAGAGCGCGGAGTTGATGACCTTCACTCAGAAGGCGATTCGCGTCATCAAGAACGTGTCTCGGCCACATGGCTTTA
ACGTGGGCCTAAACTTGGGGACATCGGCGGGAGGATCGCTGGCCGAGCACCTGCATGTGCATGTCGTGCCACGGTGGGGT
GGCGACGCGAACTTCATCACCATCATCGGCGGCTCCAAAGTGATCCCGCAGTTGCTCCGGGATACTCGACAGCTGCTTGC
GACGGAGTGGACGAAACAGTTTATGAGCCGCAGTGGCGACGATGCAGAGCGAAGCTTATGA

Upstream 100 bases:

>100_bases
AACGGCGTCGCCCGCGACAGTGCCGTCGAGGCCATCGTTTGTTGGATCGTTGACCGCGAGAATGATTTTCCCACAGCAGA
ATTGGTGAAAGTAACCGGCG

Downstream 100 bases:

>100_bases
GCAAGGTGCCATTCCTGTCCCGGGCGACGTTTACGCGGCTCACGACTCCGACCGCAAGAGCGTTGCTGCGGGTCGGCTTG
ACGCCGGATGCCATCACCGT

Product: hypothetical protein

Products: NA

Alternate protein names: ATP adenylyltransferase; Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase; AP,A phosphorylase [H]

Number of amino acids: Translated: 206; Mature: 205

Protein sequence:

>206_residues
MSEQERPDTRADHTDGTILDMGVGERDHLQRLWTPYRMTYLAEAPVNHDNSTPAQPFTDIPQLSDEDGLVVARGELVYAV
LNLYPYNPGHLMVVPYRQVSELEDLTDAESAELMTFTQKAIRVIKNVSRPHGFNVGLNLGTSAGGSLAEHLHVHVVPRWG
GDANFITIIGGSKVIPQLLRDTRQLLATEWTKQFMSRSGDDAERSL

Sequences:

>Translated_206_residues
MSEQERPDTRADHTDGTILDMGVGERDHLQRLWTPYRMTYLAEAPVNHDNSTPAQPFTDIPQLSDEDGLVVARGELVYAV
LNLYPYNPGHLMVVPYRQVSELEDLTDAESAELMTFTQKAIRVIKNVSRPHGFNVGLNLGTSAGGSLAEHLHVHVVPRWG
GDANFITIIGGSKVIPQLLRDTRQLLATEWTKQFMSRSGDDAERSL
>Mature_205_residues
SEQERPDTRADHTDGTILDMGVGERDHLQRLWTPYRMTYLAEAPVNHDNSTPAQPFTDIPQLSDEDGLVVARGELVYAVL
NLYPYNPGHLMVVPYRQVSELEDLTDAESAELMTFTQKAIRVIKNVSRPHGFNVGLNLGTSAGGSLAEHLHVHVVPRWGG
DANFITIIGGSKVIPQLLRDTRQLLATEWTKQFMSRSGDDAERSL

Specific function: Catabolizes diadenosine 5',5'''-P1,P4-tetraphosphate (Ap4A) into ADP and ATP. It does not catalyze the reverse phosphorolysis reaction. The optimum substrates are dinucleoside polyphosphates containing four or five phosphate residues [H]

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR001310 [H]

Pfam domain/function: PF01230 HIT [H]

EC number: =2.7.7.53 [H]

Molecular weight: Translated: 22962; Mature: 22831

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEQERPDTRADHTDGTILDMGVGERDHLQRLWTPYRMTYLAEAPVNHDNSTPAQPFTDI
CCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHCCHHHHEEEEECCCCCCCCCCCCCCCCC
PQLSDEDGLVVARGELVYAVLNLYPYNPGHLMVVPYRQVSELEDLTDAESAELMTFTQKA
CCCCCCCCEEEECCHHEEHHHHHCCCCCCCEEEECHHHHHHHHHHCCCCHHHHHHHHHHH
IRVIKNVSRPHGFNVGLNLGTSAGGSLAEHLHVHVVPRWGGDANFITIIGGSKVIPQLLR
HHHHHHCCCCCCCEEEEECCCCCCCHHHHCEEEEEEECCCCCCCEEEEECCCHHHHHHHH
DTRQLLATEWTKQFMSRSGDDAERSL
HHHHHHHHHHHHHHHHCCCCCHHCCC
>Mature Secondary Structure 
SEQERPDTRADHTDGTILDMGVGERDHLQRLWTPYRMTYLAEAPVNHDNSTPAQPFTDI
CCCCCCCCCCCCCCCEEEECCCCCHHHHHHHCCHHHHEEEEECCCCCCCCCCCCCCCCC
PQLSDEDGLVVARGELVYAVLNLYPYNPGHLMVVPYRQVSELEDLTDAESAELMTFTQKA
CCCCCCCCEEEECCHHEEHHHHHCCCCCCCEEEECHHHHHHHHHHCCCCHHHHHHHHHHH
IRVIKNVSRPHGFNVGLNLGTSAGGSLAEHLHVHVVPRWGGDANFITIIGGSKVIPQLLR
HHHHHHCCCCCCCEEEEECCCCCCCHHHHCEEEEEEECCCCCCCEEEEECCCHHHHHHHH
DTRQLLATEWTKQFMSRSGDDAERSL
HHHHHHHHHHHHHHHHCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12368430; 12218036 [H]