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The map label for this gene is ccpA [H]

Identifier: 220933086

GI number: 220933086

Start: 2457498

End: 2458496

Strand: Reverse

Name: ccpA [H]

Synonym: Hore_22540

Alternate gene names: 220933086

Gene position: 2458496-2457498 (Counterclockwise)

Preceding gene: 220933087

Following gene: 220933085

Centisome position: 95.36

GC content: 41.24

Gene sequence:

>999_bases
ATGAAACCTACCATTAAAGATGTTGCCAGAAAAGCCAATGTGTCGGTGGCTACTGTATCCCGGGTTTTAAATAACCAGCC
CGGGTATTCTGTGGAAACTGAAAAAAAGGTCCTTGAGGCTATAGATGAACTTGGATACCATCCCAATGCCCTGGCCCGGG
GGCTGGTTGGGAAAAGGACAAAAACGCTGGGGGTTTTAATCCCGCGGATATCCAACATGGTTAGTTCTCAGATAATGAAT
GGTATTGAAGATGCGGCCCATAAAAACGACCACAGTGTCATTATCTGTAATACCGATAATGATGGGCAAAAAACGATGGT
ATATCTCGATGTGTTGCGGGAAAAGCGGGTAGATGGAATCATTGTTGTCAGTGAAATGTTGACTGAGGAATATGCCAATA
AACTGGTAGAATTAAAGGTTCCGGTGATCTTGATTTCTACTATAGATGAAACAGGACAATTCCCCCATATAAAAGTCAAT
GATGAACAGGCTGCTTATCAGGCTACTGAATACCTTATCAGTAAGGGTCATAAAAATATAGCCATGATAAGCGGTACCCC
GGAGGATATGGTTGCCGGTAAACCCAGGCTTGATGGATATAAGAAGGCTTTAAGGGAAAATGGACTACCGGTTAAAGAAG
AGAACATAGTCTTTGGAGATTTCTGGTTTGACAGTGGTAAGGAATGTATGGAAAGACTTTTAAACAATAATCAAGGTATT
ACGGCCATTTTCGTGGCCAGTGATGAAATGGCGGCCGGGGCTTTATCGACCGCTTATAAATCCGGAATCAGGGTACCTGA
AGATATATCTATAATCGGATTTGATAATACCCAGCTTGCTGAAATGACTATTCCACCACTGACTACAGTCAGTCAGCCCT
TTTATCAAATGGGTTATAAGGGCTTAAAGCTCTTATTAAAAGCAATAAAAGGAAAGGAAGTAAATAGTGCCATTTTACCT
CATGTTATAGTGGAAAGGGAAACAGTTAAAAAAGTTTGA

Upstream 100 bases:

>100_bases
TTACTAAATTGATATTTACTAAATTTATACTTACTAAATTGATATTTACCAAATTAATATTTACTAAATTAACCAATATT
ATATAAGGGGTTTTAGGGAT

Downstream 100 bases:

>100_bases
TTATGTTAAAATGGGGGTGTTATTTTTAAGGAAAACAGGCATATAGGTTTTAGTGAGGTATTAAAATTATTTAAGTGTTT
AGTAAACGTTTACTCAAATA

Product: LacI family transcriptional regulator

Products: NA

Alternate protein names: Catabolite control protein [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MKPTIKDVARKANVSVATVSRVLNNQPGYSVETEKKVLEAIDELGYHPNALARGLVGKRTKTLGVLIPRISNMVSSQIMN
GIEDAAHKNDHSVIICNTDNDGQKTMVYLDVLREKRVDGIIVVSEMLTEEYANKLVELKVPVILISTIDETGQFPHIKVN
DEQAAYQATEYLISKGHKNIAMISGTPEDMVAGKPRLDGYKKALRENGLPVKEENIVFGDFWFDSGKECMERLLNNNQGI
TAIFVASDEMAAGALSTAYKSGIRVPEDISIIGFDNTQLAEMTIPPLTTVSQPFYQMGYKGLKLLLKAIKGKEVNSAILP
HVIVERETVKKV

Sequences:

>Translated_332_residues
MKPTIKDVARKANVSVATVSRVLNNQPGYSVETEKKVLEAIDELGYHPNALARGLVGKRTKTLGVLIPRISNMVSSQIMN
GIEDAAHKNDHSVIICNTDNDGQKTMVYLDVLREKRVDGIIVVSEMLTEEYANKLVELKVPVILISTIDETGQFPHIKVN
DEQAAYQATEYLISKGHKNIAMISGTPEDMVAGKPRLDGYKKALRENGLPVKEENIVFGDFWFDSGKECMERLLNNNQGI
TAIFVASDEMAAGALSTAYKSGIRVPEDISIIGFDNTQLAEMTIPPLTTVSQPFYQMGYKGLKLLLKAIKGKEVNSAILP
HVIVERETVKKV
>Mature_332_residues
MKPTIKDVARKANVSVATVSRVLNNQPGYSVETEKKVLEAIDELGYHPNALARGLVGKRTKTLGVLIPRISNMVSSQIMN
GIEDAAHKNDHSVIICNTDNDGQKTMVYLDVLREKRVDGIIVVSEMLTEEYANKLVELKVPVILISTIDETGQFPHIKVN
DEQAAYQATEYLISKGHKNIAMISGTPEDMVAGKPRLDGYKKALRENGLPVKEENIVFGDFWFDSGKECMERLLNNNQGI
TAIFVASDEMAAGALSTAYKSGIRVPEDISIIGFDNTQLAEMTIPPLTTVSQPFYQMGYKGLKLLLKAIKGKEVNSAILP
HVIVERETVKKV

Specific function: Transcriptional regulator involved in both the repression of carbohydrate utilization genes such as the alpha- amylase (amyE) and the acetyl-coenzyme A synthetase (acsA); and in the positive regulation of genes involved in excretion of excess carbon such

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=313, Percent_Identity=37.6996805111821, Blast_Score=218, Evalue=3e-58,
Organism=Escherichia coli, GI1790194, Length=308, Percent_Identity=36.3636363636364, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI1787948, Length=330, Percent_Identity=35.4545454545455, Blast_Score=191, Evalue=6e-50,
Organism=Escherichia coli, GI1789202, Length=295, Percent_Identity=33.5593220338983, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1788474, Length=332, Percent_Identity=32.2289156626506, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1786540, Length=333, Percent_Identity=33.6336336336336, Blast_Score=158, Evalue=5e-40,
Organism=Escherichia coli, GI1789068, Length=300, Percent_Identity=30, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1787580, Length=320, Percent_Identity=29.6875, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI48994940, Length=320, Percent_Identity=27.1875, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1787906, Length=325, Percent_Identity=26.1538461538462, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1790715, Length=313, Percent_Identity=25.2396166134185, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1786268, Length=309, Percent_Identity=22.9773462783171, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1790689, Length=320, Percent_Identity=25.3125, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1789456, Length=327, Percent_Identity=28.7461773700306, Blast_Score=93, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006377
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36599; Mature: 36599

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPTIKDVARKANVSVATVSRVLNNQPGYSVETEKKVLEAIDELGYHPNALARGLVGKRT
CCCCHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCH
KTLGVLIPRISNMVSSQIMNGIEDAAHKNDHSVIICNTDNDGQKTMVYLDVLREKRVDGI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCE
IVVSEMLTEEYANKLVELKVPVILISTIDETGQFPHIKVNDEQAAYQATEYLISKGHKNI
EEHHHHHHHHHHHHHEEEECCEEEEEECCCCCCCCEEEECCHHHHHHHHHHHHHCCCCCE
AMISGTPEDMVAGKPRLDGYKKALRENGLPVKEENIVFGDFWFDSGKECMERLLNNNQGI
EEEECCCHHHHCCCCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCE
TAIFVASDEMAAGALSTAYKSGIRVPEDISIIGFDNTQLAEMTIPPLTTVSQPFYQMGYK
EEEEEECCCHHHHHHHHHHHCCCCCCCCCEEEECCCCEEEEEECCCCHHCCCHHHHHHHH
GLKLLLKAIKGKEVNSAILPHVIVERETVKKV
HHHHHHHHHCCCCCCHHHHHHHHHCHHHHHCC
>Mature Secondary Structure
MKPTIKDVARKANVSVATVSRVLNNQPGYSVETEKKVLEAIDELGYHPNALARGLVGKRT
CCCCHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCH
KTLGVLIPRISNMVSSQIMNGIEDAAHKNDHSVIICNTDNDGQKTMVYLDVLREKRVDGI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCE
IVVSEMLTEEYANKLVELKVPVILISTIDETGQFPHIKVNDEQAAYQATEYLISKGHKNI
EEHHHHHHHHHHHHHEEEECCEEEEEECCCCCCCCEEEECCHHHHHHHHHHHHHCCCCCE
AMISGTPEDMVAGKPRLDGYKKALRENGLPVKEENIVFGDFWFDSGKECMERLLNNNQGI
EEEECCCHHHHCCCCCCHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCE
TAIFVASDEMAAGALSTAYKSGIRVPEDISIIGFDNTQLAEMTIPPLTTVSQPFYQMGYK
EEEEEECCCHHHHHHHHHHHCCCCCCCCCEEEECCCCEEEEEECCCCHHCCCHHHHHHHH
GLKLLLKAIKGKEVNSAILPHVIVERETVKKV
HHHHHHHHHCCCCCCHHHHHHHHHCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8200532 [H]