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The map label for this gene is malL [H]

Identifier: 220933085

GI number: 220933085

Start: 2455649

End: 2457337

Strand: Reverse

Name: malL [H]

Synonym: Hore_22530

Alternate gene names: 220933085

Gene position: 2457337-2455649 (Counterclockwise)

Preceding gene: 220933086

Following gene: 220933084

Centisome position: 95.31

GC content: 43.81

Gene sequence:

>1689_bases
ATGGAAAGAAAATGGTGGAAAGAAGGGGTGGTTTATCAAATTTACCCCAGGAGTTTCAATGATAGTAATGGTGATGGTAT
CGGTGACCTGCCGGGTATTATCGAAAAACTGGATTACTTAAAGGAGCTGGGGGTAGATATTATTTGGTTATGCCCTGTTT
ATAAATCCCCCAATGATGATAATGGTTATGATATCAGTGATTATTATGATATTATGGATGAGTTCGGAACAATGGAGGAT
ATGGATAAACTAATTGAAGGGGTCCATAAGCGGGGCATGAAGTTAATTATGGACCTGGTGGTCAACCATACCTCTGATGA
ACACCCCTGGTTTCAGGAGTCGAAATCATCTAAAGATAACCCTTATCGCGACTTTTATATCTGGCGAAAGGGTAAAAACG
ACGGGCCGCCCAATAACTGGGGTTCTGCCTTCAGTGGCTCTGCCTGGGAATATGATGAAAAAACCGGGGAGTATTACCTT
CACCTTTTCTCTAAAAAGCAGCCTGACCTGAACTGGGAAAACCCCCGGGTCAGGGAAGAGGTTTACAAAATGATGAGATG
GTGGCTTGATAAAGGTATTGACGGTTTCCGGATGGATGTAATTAATATGATCTCCAAGGTAAAGGGACTACCGGATGGTA
AGGTATACCCCGGGGCCAAATATGGTGATGGCAGCCCTTATTATCTGAATGGTCCCAGGGTTCATGATTATCTACAGGAG
ATGAACAGGGAGGTTCTCTCGAAATATGATGTCATGACCGTCGGGGAGACCCCGGGGGTTACCCCTGAGATTGCCAGAAA
GTATGTTGGTTATGACCGAAATGAACTTAATATGGTCTTCCAGTTTGAGCTGATGGGGATTGACTGCGGGTTAAGTAAAT
GGGATAAAAAAGACTGGAAGCTTACCGAGTTTAAAAGAATTTTCAATAGATGGTATGAGGGATTAAAAGAGAAAGGCTGG
AACAGTCTTTATATGAATAACCATGACCAACCGAGGATGGTTCCCCGCTTTGGTAATGATAAGGAATACCGGGTAGAATC
GGCGAAACTGCTGGCAACCCTGCTCCATACCTTTCCCGGTACCCCCTATATTTACCAGGGTGAAGAGATCGGGATGACCA
ATGTGGCTTTTGACAGTATCGAAGACTACCGGGATATTGAGACCCTCAACTGGTATAGGGAACAGATAGAAGAGGGAAGG
ACTGAGGCAGAAGTTATGGAAGCAATCCACTGGGCCAGCCGTGATAATGCCCGGACTCCCATGCAGTGGGATGATAGTCC
CCATGCCGGTTTTACCACAGGTACCCCCTGGGTTAAGGTAAACCCCAATTATAAAGATATCAATGTTGCTAAAGCCCGTA
AAGACCAGGATTCCATCTTCCATTATTACCGGAGGTTAATTCAGTTAAGGAAGGAAAATCCCGTAATTGTCTACGGTGAT
TACAGGCCTATCCTTGAAGATGATGAAAAGCTCTTTTCCTATCTCAGGACCCTTAATGAAGATGGGGAAGAAAGCCGCCT
TCTGGTTATACTCAATTTCTCGGAAGAAGAGGTTAAATTTAAATTACCGGAAGGTATTGGTTACAGCGATAAAAAGATAT
TGATTGGAAATTACCCGGTTGGGTTACAGAAGGATTTATCCAATTTAACCCTGAAGCCCTATGAGGCTCTTGTTTACCAG
TTAATATAA

Upstream 100 bases:

>100_bases
TTAAAATTATTTAAGTGTTTAGTAAACGTTTACTCAAATAAAAAATGGGGGACTGTAATATTTCTTAAAATAAAAATAGT
TAATAATGGAGGGATGGCCT

Downstream 100 bases:

>100_bases
GTATTTCTTATGATTTTTAAGTATCATATTAATATATATCAACAAATATGGGGGTAGATGTCAGTAAAACAAATAAATTT
TTATGGAAAAGGACCCGTAA

Product: alpha amylase catalytic subunit

Products: NA

Alternate protein names: Dextrin 6-alpha-D-glucanohydrolase; Oligosaccharide alpha-1,6-glucosidase; Sucrase-isomaltase; Isomaltase [H]

Number of amino acids: Translated: 562; Mature: 562

Protein sequence:

>562_residues
MERKWWKEGVVYQIYPRSFNDSNGDGIGDLPGIIEKLDYLKELGVDIIWLCPVYKSPNDDNGYDISDYYDIMDEFGTMED
MDKLIEGVHKRGMKLIMDLVVNHTSDEHPWFQESKSSKDNPYRDFYIWRKGKNDGPPNNWGSAFSGSAWEYDEKTGEYYL
HLFSKKQPDLNWENPRVREEVYKMMRWWLDKGIDGFRMDVINMISKVKGLPDGKVYPGAKYGDGSPYYLNGPRVHDYLQE
MNREVLSKYDVMTVGETPGVTPEIARKYVGYDRNELNMVFQFELMGIDCGLSKWDKKDWKLTEFKRIFNRWYEGLKEKGW
NSLYMNNHDQPRMVPRFGNDKEYRVESAKLLATLLHTFPGTPYIYQGEEIGMTNVAFDSIEDYRDIETLNWYREQIEEGR
TEAEVMEAIHWASRDNARTPMQWDDSPHAGFTTGTPWVKVNPNYKDINVAKARKDQDSIFHYYRRLIQLRKENPVIVYGD
YRPILEDDEKLFSYLRTLNEDGEESRLLVILNFSEEEVKFKLPEGIGYSDKKILIGNYPVGLQKDLSNLTLKPYEALVYQ
LI

Sequences:

>Translated_562_residues
MERKWWKEGVVYQIYPRSFNDSNGDGIGDLPGIIEKLDYLKELGVDIIWLCPVYKSPNDDNGYDISDYYDIMDEFGTMED
MDKLIEGVHKRGMKLIMDLVVNHTSDEHPWFQESKSSKDNPYRDFYIWRKGKNDGPPNNWGSAFSGSAWEYDEKTGEYYL
HLFSKKQPDLNWENPRVREEVYKMMRWWLDKGIDGFRMDVINMISKVKGLPDGKVYPGAKYGDGSPYYLNGPRVHDYLQE
MNREVLSKYDVMTVGETPGVTPEIARKYVGYDRNELNMVFQFELMGIDCGLSKWDKKDWKLTEFKRIFNRWYEGLKEKGW
NSLYMNNHDQPRMVPRFGNDKEYRVESAKLLATLLHTFPGTPYIYQGEEIGMTNVAFDSIEDYRDIETLNWYREQIEEGR
TEAEVMEAIHWASRDNARTPMQWDDSPHAGFTTGTPWVKVNPNYKDINVAKARKDQDSIFHYYRRLIQLRKENPVIVYGD
YRPILEDDEKLFSYLRTLNEDGEESRLLVILNFSEEEVKFKLPEGIGYSDKKILIGNYPVGLQKDLSNLTLKPYEALVYQ
LI
>Mature_562_residues
MERKWWKEGVVYQIYPRSFNDSNGDGIGDLPGIIEKLDYLKELGVDIIWLCPVYKSPNDDNGYDISDYYDIMDEFGTMED
MDKLIEGVHKRGMKLIMDLVVNHTSDEHPWFQESKSSKDNPYRDFYIWRKGKNDGPPNNWGSAFSGSAWEYDEKTGEYYL
HLFSKKQPDLNWENPRVREEVYKMMRWWLDKGIDGFRMDVINMISKVKGLPDGKVYPGAKYGDGSPYYLNGPRVHDYLQE
MNREVLSKYDVMTVGETPGVTPEIARKYVGYDRNELNMVFQFELMGIDCGLSKWDKKDWKLTEFKRIFNRWYEGLKEKGW
NSLYMNNHDQPRMVPRFGNDKEYRVESAKLLATLLHTFPGTPYIYQGEEIGMTNVAFDSIEDYRDIETLNWYREQIEEGR
TEAEVMEAIHWASRDNARTPMQWDDSPHAGFTTGTPWVKVNPNYKDINVAKARKDQDSIFHYYRRLIQLRKENPVIVYGD
YRPILEDDEKLFSYLRTLNEDGEESRLLVILNFSEEEVKFKLPEGIGYSDKKILIGNYPVGLQKDLSNLTLKPYEALVYQ
LI

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=539, Percent_Identity=32.2820037105751, Blast_Score=274, Evalue=2e-73,
Organism=Homo sapiens, GI61744479, Length=134, Percent_Identity=31.3432835820896, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI61744475, Length=134, Percent_Identity=31.3432835820896, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI65506891, Length=134, Percent_Identity=31.3432835820896, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI61744481, Length=134, Percent_Identity=31.3432835820896, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI61744477, Length=134, Percent_Identity=31.3432835820896, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI61744483, Length=134, Percent_Identity=31.3432835820896, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1790687, Length=554, Percent_Identity=44.7653429602888, Blast_Score=509, Evalue=1e-145,
Organism=Escherichia coli, GI1786604, Length=386, Percent_Identity=25.1295336787565, Blast_Score=99, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI32565753, Length=537, Percent_Identity=25.3258845437616, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI25147709, Length=534, Percent_Identity=25.4681647940075, Blast_Score=135, Evalue=6e-32,
Organism=Saccharomyces cerevisiae, GI6321726, Length=588, Percent_Identity=44.2176870748299, Blast_Score=447, Evalue=1e-126,
Organism=Saccharomyces cerevisiae, GI6322245, Length=582, Percent_Identity=41.9243986254296, Blast_Score=443, Evalue=1e-125,
Organism=Saccharomyces cerevisiae, GI6324416, Length=588, Percent_Identity=43.5374149659864, Blast_Score=436, Evalue=1e-123,
Organism=Saccharomyces cerevisiae, GI6322241, Length=588, Percent_Identity=43.5374149659864, Blast_Score=435, Evalue=1e-122,
Organism=Saccharomyces cerevisiae, GI6322021, Length=588, Percent_Identity=43.5374149659864, Blast_Score=435, Evalue=1e-122,
Organism=Saccharomyces cerevisiae, GI6321731, Length=592, Percent_Identity=41.3851351351351, Blast_Score=399, Evalue=1e-112,
Organism=Saccharomyces cerevisiae, GI6319776, Length=592, Percent_Identity=41.3851351351351, Blast_Score=399, Evalue=1e-112,
Organism=Drosophila melanogaster, GI221330053, Length=600, Percent_Identity=36.5, Blast_Score=322, Evalue=6e-88,
Organism=Drosophila melanogaster, GI24583745, Length=580, Percent_Identity=35, Blast_Score=300, Evalue=2e-81,
Organism=Drosophila melanogaster, GI24586591, Length=588, Percent_Identity=36.2244897959184, Blast_Score=297, Evalue=2e-80,
Organism=Drosophila melanogaster, GI24586593, Length=587, Percent_Identity=34.0715502555366, Blast_Score=295, Evalue=7e-80,
Organism=Drosophila melanogaster, GI24583747, Length=555, Percent_Identity=34.4144144144144, Blast_Score=284, Evalue=9e-77,
Organism=Drosophila melanogaster, GI24583749, Length=555, Percent_Identity=34.4144144144144, Blast_Score=284, Evalue=1e-76,
Organism=Drosophila melanogaster, GI45549022, Length=525, Percent_Identity=36, Blast_Score=283, Evalue=3e-76,
Organism=Drosophila melanogaster, GI24586597, Length=591, Percent_Identity=31.9796954314721, Blast_Score=281, Evalue=1e-75,
Organism=Drosophila melanogaster, GI24586587, Length=583, Percent_Identity=33.4476843910806, Blast_Score=279, Evalue=4e-75,
Organism=Drosophila melanogaster, GI24586599, Length=590, Percent_Identity=33.0508474576271, Blast_Score=278, Evalue=6e-75,
Organism=Drosophila melanogaster, GI24586589, Length=592, Percent_Identity=32.7702702702703, Blast_Score=278, Evalue=1e-74,
Organism=Drosophila melanogaster, GI281360393, Length=531, Percent_Identity=31.0734463276836, Blast_Score=216, Evalue=2e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.10 [H]

Molecular weight: Translated: 66166; Mature: 66166

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERKWWKEGVVYQIYPRSFNDSNGDGIGDLPGIIEKLDYLKELGVDIIWLCPVYKSPNDD
CCCCHHHCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCC
NGYDISDYYDIMDEFGTMEDMDKLIEGVHKRGMKLIMDLVVNHTSDEHPWFQESKSSKDN
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCC
PYRDFYIWRKGKNDGPPNNWGSAFSGSAWEYDEKTGEYYLHLFSKKQPDLNWENPRVREE
CCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHH
VYKMMRWWLDKGIDGFRMDVINMISKVKGLPDGKVYPGAKYGDGSPYYLNGPRVHDYLQE
HHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHH
MNREVLSKYDVMTVGETPGVTPEIARKYVGYDRNELNMVFQFELMGIDCGLSKWDKKDWK
HHHHHHHHCCEEEECCCCCCCHHHHHHHHCCCCCCCEEEEEEEEEEEECCCCCCCCCCCC
LTEFKRIFNRWYEGLKEKGWNSLYMNNHDQPRMVPRFGNDKEYRVESAKLLATLLHTFPG
HHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
TPYIYQGEEIGMTNVAFDSIEDYRDIETLNWYREQIEEGRTEAEVMEAIHWASRDNARTP
CCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCC
MQWDDSPHAGFTTGTPWVKVNPNYKDINVAKARKDQDSIFHYYRRLIQLRKENPVIVYGD
CCCCCCCCCCCCCCCCEEEECCCCCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCEEEECC
YRPILEDDEKLFSYLRTLNEDGEESRLLVILNFSEEEVKFKLPEGIGYSDKKILIGNYPV
CCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEEECCCCCCCCCCEEEECCCCC
GLQKDLSNLTLKPYEALVYQLI
CHHHHHHCCCCCHHHHHHHHCC
>Mature Secondary Structure
MERKWWKEGVVYQIYPRSFNDSNGDGIGDLPGIIEKLDYLKELGVDIIWLCPVYKSPNDD
CCCCHHHCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCC
NGYDISDYYDIMDEFGTMEDMDKLIEGVHKRGMKLIMDLVVNHTSDEHPWFQESKSSKDN
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCC
PYRDFYIWRKGKNDGPPNNWGSAFSGSAWEYDEKTGEYYLHLFSKKQPDLNWENPRVREE
CCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHH
VYKMMRWWLDKGIDGFRMDVINMISKVKGLPDGKVYPGAKYGDGSPYYLNGPRVHDYLQE
HHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHH
MNREVLSKYDVMTVGETPGVTPEIARKYVGYDRNELNMVFQFELMGIDCGLSKWDKKDWK
HHHHHHHHCCEEEECCCCCCCHHHHHHHHCCCCCCCEEEEEEEEEEEECCCCCCCCCCCC
LTEFKRIFNRWYEGLKEKGWNSLYMNNHDQPRMVPRFGNDKEYRVESAKLLATLLHTFPG
HHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
TPYIYQGEEIGMTNVAFDSIEDYRDIETLNWYREQIEEGRTEAEVMEAIHWASRDNARTP
CCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCC
MQWDDSPHAGFTTGTPWVKVNPNYKDINVAKARKDQDSIFHYYRRLIQLRKENPVIVYGD
CCCCCCCCCCCCCCCCEEEECCCCCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCEEEECC
YRPILEDDEKLFSYLRTLNEDGEESRLLVILNFSEEEVKFKLPEGIGYSDKKILIGNYPV
CCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEEECCCCCCCCCCEEEECCCCC
GLQKDLSNLTLKPYEALVYQLI
CHHHHHHCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1761534 [H]