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The map label for this gene is baeS [H]

Identifier: 220932166

GI number: 220932166

Start: 1428088

End: 1429479

Strand: Direct

Name: baeS [H]

Synonym: Hore_13290

Alternate gene names: 220932166

Gene position: 1428088-1429479 (Clockwise)

Preceding gene: 220932165

Following gene: 220932167

Centisome position: 55.39

GC content: 37.0

Gene sequence:

>1392_bases
ATGAGTAAACTGGGTATAAAAATTTTTTTAATAATGTTATCAGTAGCTATAATGGGTTTAGTATTTATAGGTTTATACCT
GAATTATAGCATTCCCGAACATTTTAAAGACTATCTATACCTGGAGAAAAAAGAAAAAATAGAAAATCTTGTTTCGGTGC
TGGAAAACAATTACAAAGAGACCCGGAGCCTTAGGAATAGCCAGAGGTTACTGTCAGAGTTCTCCCGGATAAATAATGTA
AATTTAAAGCTTACTGATGCCAGGGGTAATATAATTTATAGTTCTACCCCAATGCCCGGGAGAATGATGAAGGGTTATTG
TATAACCCCTTTCAGAAGAAGAATAATGGTAGAACGAAATTATCCCCTCGGTTATGAGGCCTTTAACCTGTCAAATAATA
ACCAAACAATCGGGAAACTCTACTGGTTACGTTTTGAAGGCCCTTATATTCCCATTAAATCCAGTTTATTCGTTAGAAAA
ATTAACAGGGCAATTATCTTTTCGGCTATAATTATTGCCATTATTACCATGGTCTTTAGTTATTTTCTATCCCGGTATTT
AACAAAACCTTTAATCAAAATTAATAATGTAGCTAAAAAAGTAGCCGATGGGCAGTTAGACCACCATGTTACTGTTAAGG
GAAATGATGAAATTAAAGAACTGGCTACTTCATTTAATCAAATGGTTGCTAAGTTAAAATATCTGGAGACAGTAAGGCGG
AAATCAACCTCAGACCTGGCCCATGAACTGCGGACCCCTCTTACCAATATAAAGGGTTACCTGGAAGGAATTAAAGAAGG
GGTCCTTGAAGTTGATTCAGTTACCCTGACCGAAATTGACGAAGAAATCAATAGATTAATAAGGCTTATAAATAGACTAA
ACGACCTTGCCACGGCTGAAAAATATATAATTCAGGGTAAAAAGAAAAAAATAAAACTGGCCAATTTTCTAGAAGACCTC
CTTAATTCCTATCTCCCCCAGGCCCGGGAAAAACAGATTGACCTTATCAAAAAATACAACCCGGAACAATCTATTTTTAT
AGACAGTAATGAAGACGCCCTGAGGACGATTTTTGGTAACCTTATCAATAATTCCCTGAAATATACCCCTGAGGGTGGTA
AAATTGAAATAACCCTCTCTTCTAAAAAAAATCAGGCAATAATTAGTGTAAAGGATAATGGAACAGGTATTTCTGCAGAA
GACCTCCCCTATATCTTTGAGCGTTTTTACCGGGCTGATAAATCCCGGTCTACCAGGTCCGGGGGAACAGGAATTGGGTT
AACCATTACCAGGGAGTTAGTTAACTCCATAGGCGGAAAAATAATTGCCTCCAGTGAAGGAAGAGGTAAAGGTGCAACCT
TTACCGTTTATCTACCATCCAGAAATAACTGA

Upstream 100 bases:

>100_bases
GATGCCCATATAAAAAATATCCGGAAAAAGCTTAATCTAGAAAAAAACCAACTTATTATAACTGTATATGGTGTCGGCTA
TAAATTTGAGGGGGATTAAA

Downstream 100 bases:

>100_bases
AATTATTTTATTTAAATTCATATTTTCTTCAAATTTATCTCCTATAATTATAACAGGGTCGAAAAATACAGATTAAATAA
CGGCAAAGCAGAAACGGCCC

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MSKLGIKIFLIMLSVAIMGLVFIGLYLNYSIPEHFKDYLYLEKKEKIENLVSVLENNYKETRSLRNSQRLLSEFSRINNV
NLKLTDARGNIIYSSTPMPGRMMKGYCITPFRRRIMVERNYPLGYEAFNLSNNNQTIGKLYWLRFEGPYIPIKSSLFVRK
INRAIIFSAIIIAIITMVFSYFLSRYLTKPLIKINNVAKKVADGQLDHHVTVKGNDEIKELATSFNQMVAKLKYLETVRR
KSTSDLAHELRTPLTNIKGYLEGIKEGVLEVDSVTLTEIDEEINRLIRLINRLNDLATAEKYIIQGKKKKIKLANFLEDL
LNSYLPQAREKQIDLIKKYNPEQSIFIDSNEDALRTIFGNLINNSLKYTPEGGKIEITLSSKKNQAIISVKDNGTGISAE
DLPYIFERFYRADKSRSTRSGGTGIGLTITRELVNSIGGKIIASSEGRGKGATFTVYLPSRNN

Sequences:

>Translated_463_residues
MSKLGIKIFLIMLSVAIMGLVFIGLYLNYSIPEHFKDYLYLEKKEKIENLVSVLENNYKETRSLRNSQRLLSEFSRINNV
NLKLTDARGNIIYSSTPMPGRMMKGYCITPFRRRIMVERNYPLGYEAFNLSNNNQTIGKLYWLRFEGPYIPIKSSLFVRK
INRAIIFSAIIIAIITMVFSYFLSRYLTKPLIKINNVAKKVADGQLDHHVTVKGNDEIKELATSFNQMVAKLKYLETVRR
KSTSDLAHELRTPLTNIKGYLEGIKEGVLEVDSVTLTEIDEEINRLIRLINRLNDLATAEKYIIQGKKKKIKLANFLEDL
LNSYLPQAREKQIDLIKKYNPEQSIFIDSNEDALRTIFGNLINNSLKYTPEGGKIEITLSSKKNQAIISVKDNGTGISAE
DLPYIFERFYRADKSRSTRSGGTGIGLTITRELVNSIGGKIIASSEGRGKGATFTVYLPSRNN
>Mature_462_residues
SKLGIKIFLIMLSVAIMGLVFIGLYLNYSIPEHFKDYLYLEKKEKIENLVSVLENNYKETRSLRNSQRLLSEFSRINNVN
LKLTDARGNIIYSSTPMPGRMMKGYCITPFRRRIMVERNYPLGYEAFNLSNNNQTIGKLYWLRFEGPYIPIKSSLFVRKI
NRAIIFSAIIIAIITMVFSYFLSRYLTKPLIKINNVAKKVADGQLDHHVTVKGNDEIKELATSFNQMVAKLKYLETVRRK
STSDLAHELRTPLTNIKGYLEGIKEGVLEVDSVTLTEIDEEINRLIRLINRLNDLATAEKYIIQGKKKKIKLANFLEDLL
NSYLPQAREKQIDLIKKYNPEQSIFIDSNEDALRTIFGNLINNSLKYTPEGGKIEITLSSKKNQAIISVKDNGTGISAED
LPYIFERFYRADKSRSTRSGGTGIGLTITRELVNSIGGKIIASSEGRGKGATFTVYLPSRNN

Specific function: Member of the two-component regulatory system BaeS/BaeR. May activate BaeR by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=275, Percent_Identity=32, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1786600, Length=239, Percent_Identity=34.3096234309623, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1786783, Length=462, Percent_Identity=25.974025974026, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1790346, Length=293, Percent_Identity=31.3993174061433, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI1787894, Length=308, Percent_Identity=25.974025974026, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1789149, Length=332, Percent_Identity=27.710843373494, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1789808, Length=293, Percent_Identity=24.2320819112628, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1790551, Length=311, Percent_Identity=25.7234726688103, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI87082128, Length=312, Percent_Identity=23.7179487179487, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI48994928, Length=245, Percent_Identity=31.4285714285714, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI145693157, Length=251, Percent_Identity=27.0916334661355, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788713, Length=264, Percent_Identity=27.2727272727273, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1789403, Length=272, Percent_Identity=27.5735294117647, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790436, Length=222, Percent_Identity=29.7297297297297, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1788549, Length=222, Percent_Identity=29.7297297297297, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790861, Length=298, Percent_Identity=24.8322147651007, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1788279, Length=309, Percent_Identity=29.7734627831715, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI87081816, Length=253, Percent_Identity=26.8774703557312, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786912, Length=235, Percent_Identity=28.5106382978723, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790300, Length=259, Percent_Identity=28.1853281853282, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1787374, Length=295, Percent_Identity=24.0677966101695, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 52745; Mature: 52614

Theoretical pI: Translated: 10.19; Mature: 10.19

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLGIKIFLIMLSVAIMGLVFIGLYLNYSIPEHFKDYLYLEKKEKIENLVSVLENNYKE
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
TRSLRNSQRLLSEFSRINNVNLKLTDARGNIIYSSTPMPGRMMKGYCITPFRRRIMVERN
HHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEECCCCCCHHCCCCCCCHHHHHEEEECC
YPLGYEAFNLSNNNQTIGKLYWLRFEGPYIPIKSSLFVRKINRAIIFSAIIIAIITMVFS
CCCCCEEEECCCCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
YFLSRYLTKPLIKINNVAKKVADGQLDHHVTVKGNDEIKELATSFNQMVAKLKYLETVRR
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
KSTSDLAHELRTPLTNIKGYLEGIKEGVLEVDSVTLTEIDEEINRLIRLINRLNDLATAE
CCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KYIIQGKKKKIKLANFLEDLLNSYLPQAREKQIDLIKKYNPEQSIFIDSNEDALRTIFGN
HHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHH
LINNSLKYTPEGGKIEITLSSKKNQAIISVKDNGTGISAEDLPYIFERFYRADKSRSTRS
HHCCCCEECCCCCEEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCC
GGTGIGLTITRELVNSIGGKIIASSEGRGKGATFTVYLPSRNN
CCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCEEEEECCCCCC
>Mature Secondary Structure 
SKLGIKIFLIMLSVAIMGLVFIGLYLNYSIPEHFKDYLYLEKKEKIENLVSVLENNYKE
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
TRSLRNSQRLLSEFSRINNVNLKLTDARGNIIYSSTPMPGRMMKGYCITPFRRRIMVERN
HHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEECCCCCCHHCCCCCCCHHHHHEEEECC
YPLGYEAFNLSNNNQTIGKLYWLRFEGPYIPIKSSLFVRKINRAIIFSAIIIAIITMVFS
CCCCCEEEECCCCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
YFLSRYLTKPLIKINNVAKKVADGQLDHHVTVKGNDEIKELATSFNQMVAKLKYLETVRR
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
KSTSDLAHELRTPLTNIKGYLEGIKEGVLEVDSVTLTEIDEEINRLIRLINRLNDLATAE
CCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KYIIQGKKKKIKLANFLEDLLNSYLPQAREKQIDLIKKYNPEQSIFIDSNEDALRTIFGN
HHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHH
LINNSLKYTPEGGKIEITLSSKKNQAIISVKDNGTGISAEDLPYIFERFYRADKSRSTRS
HHCCCCEECCCCCEEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCC
GGTGIGLTITRELVNSIGGKIIASSEGRGKGATFTVYLPSRNN
CCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8282725; 9097040; 9278503 [H]