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The map label for this gene is hflK [H]

Identifier: 220918767

GI number: 220918767

Start: 4096972

End: 4098024

Strand: Direct

Name: hflK [H]

Synonym: A2cp1_3678

Alternate gene names: 220918767

Gene position: 4096972-4098024 (Clockwise)

Preceding gene: 220918766

Following gene: 220918768

Centisome position: 81.46

GC content: 70.28

Gene sequence:

>1053_bases
ATGGAATCGAGCCCTCGGGTCGTGGACGGACCGCAGAAGCCGGGACCGGGTGACTTCTGGCGAGGGCTGTGGAGCGCGCT
GGGCGGGCGGCTGCCGCTCGTGATCGCCGCGCTGGTGGCGCTCGTCGGCGTGACCACGTCCTACGTCCAGGTGGAGCCGG
ACGAGGTCGGGGTCATCCTCCGCCTCGGCCGCTTCATCGGGACCGTCGAGCCCGGACCGCACTTCCGCATCCCGTTCGGC
GTCGACCGCATCACCAAGGTCCCGGTGCAGCGGCAGCTCAAGGCCGAGTTCGGCTTCCGCACCGAGCACCTCGACGGGCG
GACCACCTACCAGCCGGAGAAGCCGGAGCTGGTGCGCGAGTCGCTCATGCTGACCGGCGACCTGAACGTCGCGGTGGTGG
AGTGGATCGTCCAGTACAAGATCAAGGATCCGTACCAGTACCTGTTCAAGGTGAAGAACGTCGAGGCGATGCTGCGGGAC
ATCTCCGAGGCGTCGATGCGCGCGGTGGTCGGGGACCACTCGGTGAACGAGGTGCTCACCACCGGCCGCCAGCGGGTCGC
GACCGAGGCGAAGGCGCTGCTGCAGGGGCTCGCGGATCGCTACGAGACCGGCGTGGACATCCAGCAGGTGGTGCTGCAGG
ACGTGAACCCGCCCGACCCGGTGAAGCCGTCCTTCAACGAGGTCAACCAGGCCTTCCAGGAGAAGGAGCGCGCCATCAAC
GAGGCGTACGCCGACCTGAACCGCGAGATCCCGCGCGCGCGGGGCGAGGCGGAGGAGACGCTGCGCGCCGCCGAGGGCTA
CGCCATCGAGCGCGTGAACCGCGCCCGGGGCGAGGCCGACCGCTTCGTCCGCATCCACGAGGAGTACCGCAAGGCGCCCG
ACGTGACGCGCCGGCGCATGTACCTCGAGACGCTCGCCGAGGTGCTCCAGCGCACGCGGCAGAAGGTCGTGGTGGACGAG
TCGCACAAGGGCGTCACGCCCATGCTGTGGATGAACGGCGCCGGCGCACCGCCCGCGGCGGGCGCCGCGGCGCAGGTGAA
GGGGCAGCCATGA

Upstream 100 bases:

>100_bases
GGGCGGCTCGCCCCACCGTGAACCCCGGCCGCCGCCCCGCGTCACCGGACGTGCGCCTCGCCGGCTTGCATTTTGGGTGG
AACCGGGCGAAGCCAGATGG

Downstream 100 bases:

>100_bases
CCCGCGCAGCCGTCGTGACGGCCGTCCTCGCCGTCGTGGCCGTCTTCGCCGTGACCGCGAGCACGTACACCCTCACCGAG
AACGAGCAGGCGGTGATCAC

Product: HflK protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MESSPRVVDGPQKPGPGDFWRGLWSALGGRLPLVIAALVALVGVTTSYVQVEPDEVGVILRLGRFIGTVEPGPHFRIPFG
VDRITKVPVQRQLKAEFGFRTEHLDGRTTYQPEKPELVRESLMLTGDLNVAVVEWIVQYKIKDPYQYLFKVKNVEAMLRD
ISEASMRAVVGDHSVNEVLTTGRQRVATEAKALLQGLADRYETGVDIQQVVLQDVNPPDPVKPSFNEVNQAFQEKERAIN
EAYADLNREIPRARGEAEETLRAAEGYAIERVNRARGEADRFVRIHEEYRKAPDVTRRRMYLETLAEVLQRTRQKVVVDE
SHKGVTPMLWMNGAGAPPAAGAAAQVKGQP

Sequences:

>Translated_350_residues
MESSPRVVDGPQKPGPGDFWRGLWSALGGRLPLVIAALVALVGVTTSYVQVEPDEVGVILRLGRFIGTVEPGPHFRIPFG
VDRITKVPVQRQLKAEFGFRTEHLDGRTTYQPEKPELVRESLMLTGDLNVAVVEWIVQYKIKDPYQYLFKVKNVEAMLRD
ISEASMRAVVGDHSVNEVLTTGRQRVATEAKALLQGLADRYETGVDIQQVVLQDVNPPDPVKPSFNEVNQAFQEKERAIN
EAYADLNREIPRARGEAEETLRAAEGYAIERVNRARGEADRFVRIHEEYRKAPDVTRRRMYLETLAEVLQRTRQKVVVDE
SHKGVTPMLWMNGAGAPPAAGAAAQVKGQP
>Mature_350_residues
MESSPRVVDGPQKPGPGDFWRGLWSALGGRLPLVIAALVALVGVTTSYVQVEPDEVGVILRLGRFIGTVEPGPHFRIPFG
VDRITKVPVQRQLKAEFGFRTEHLDGRTTYQPEKPELVRESLMLTGDLNVAVVEWIVQYKIKDPYQYLFKVKNVEAMLRD
ISEASMRAVVGDHSVNEVLTTGRQRVATEAKALLQGLADRYETGVDIQQVVLQDVNPPDPVKPSFNEVNQAFQEKERAIN
EAYADLNREIPRARGEAEETLRAAEGYAIERVNRARGEADRFVRIHEEYRKAPDVTRRRMYLETLAEVLQRTRQKVVVDE
SHKGVTPMLWMNGAGAPPAAGAAAQVKGQP

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790616, Length=315, Percent_Identity=31.4285714285714, Blast_Score=151, Evalue=5e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010201
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: NA

Molecular weight: Translated: 39098; Mature: 39098

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESSPRVVDGPQKPGPGDFWRGLWSALGGRLPLVIAALVALVGVTTSYVQVEPDEVGVIL
CCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEECHHHHHHHH
RLGRFIGTVEPGPHFRIPFGVDRITKVPVQRQLKAEFGFRTEHLDGRTTYQPEKPELVRE
HHHHHHCCCCCCCCEECCCCHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHH
SLMLTGDLNVAVVEWIVQYKIKDPYQYLFKVKNVEAMLRDISEASMRAVVGDHSVNEVLT
HHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
TGRQRVATEAKALLQGLADRYETGVDIQQVVLQDVNPPDPVKPSFNEVNQAFQEKERAIN
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
EAYADLNREIPRARGEAEETLRAAEGYAIERVNRARGEADRFVRIHEEYRKAPDVTRRRM
HHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHH
YLETLAEVLQRTRQKVVVDESHKGVTPMLWMNGAGAPPAAGAAAQVKGQP
HHHHHHHHHHHHHHHEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MESSPRVVDGPQKPGPGDFWRGLWSALGGRLPLVIAALVALVGVTTSYVQVEPDEVGVIL
CCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEECHHHHHHHH
RLGRFIGTVEPGPHFRIPFGVDRITKVPVQRQLKAEFGFRTEHLDGRTTYQPEKPELVRE
HHHHHHCCCCCCCCEECCCCHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHH
SLMLTGDLNVAVVEWIVQYKIKDPYQYLFKVKNVEAMLRDISEASMRAVVGDHSVNEVLT
HHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
TGRQRVATEAKALLQGLADRYETGVDIQQVVLQDVNPPDPVKPSFNEVNQAFQEKERAIN
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHH
EAYADLNREIPRARGEAEETLRAAEGYAIERVNRARGEADRFVRIHEEYRKAPDVTRRRM
HHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHH
YLETLAEVLQRTRQKVVVDESHKGVTPMLWMNGAGAPPAAGAAAQVKGQP
HHHHHHHHHHHHHHHEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]