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The map label for this gene is hflC [H]

Identifier: 220918768

GI number: 220918768

Start: 4098021

End: 4098962

Strand: Direct

Name: hflC [H]

Synonym: A2cp1_3679

Alternate gene names: 220918768

Gene position: 4098021-4098962 (Clockwise)

Preceding gene: 220918767

Following gene: 220918770

Centisome position: 81.48

GC content: 69.53

Gene sequence:

>942_bases
ATGACCCGCGCAGCCGTCGTGACGGCCGTCCTCGCCGTCGTGGCCGTCTTCGCCGTGACCGCGAGCACGTACACCCTCAC
CGAGAACGAGCAGGCGGTGATCACCCGCTTCGGCGAGCCGCGGGGCGAGCCCATCACCGAGCCCGGCCTGCACTTCAAGC
TCCCGTTCGCCGACACCGTGAACCGGTTCGACCGGCGCTGGCTGGACTGGCGTGGCGATCCGAACCAGATCCCCACCAAG
GACAAGAAGTACATCTGGGTGGACACGTTCGGCCGGTGGCGCATCGTGGACCCGCTGCGCTTCTTCCAGCGGCTCCGGGA
CGAGCGCAATGCGCAGTCGCGGCTCGACGACATCATCGACGGCGAGACGCGCAACGCCATCGCCTCGTTCGCGCTCATCG
AAGCCGTGCGCACCACGAACCGCACCTTCGAGGACGACGAGTACTCCGCCGAGCTCGGCGGCGCCGAGGCGCTCGAGACC
GTGCAGGCGGGGCGCGACCGGCTCACCCGGCAGATCCGCGATCGCGCCGCCGAGGTGGTGAAGGAGTTCGGCGTCGAGCT
CGTGGACGTCCAGATCCGGCGGATCAACTACGTCAACGAGGTGCAGGTGAAGGTGTTCGACCGAATGATCTCCGAGCGGC
GCCGCATCGCGGAGCGCTCCCGGTCGGAGGGCATGGGCCGGGCGGCGGAGATCCGCGGCCAGCGCGAGCGCGACCTGAAG
GCGATCCGCTCCGAGGCGTACCGCAAGGCGCAGGAGGTGTCCGGCAAGGCCGACGCCGAGGCGACCCGGATCTACGCGGC
CGCCTTCGGCCGGGACCCCGAGTTCTTCCAGTTCCTGCGGACGCTCGAGGCCTACCCGCGCACCGTGGACGCCTCCACCT
CGCTGTTCCTCGGCACCGACACCGAGTTCTACCGGTACCTCCGCAGCTCGAAGAAGCAGTGA

Upstream 100 bases:

>100_bases
TGGTGGACGAGTCGCACAAGGGCGTCACGCCCATGCTGTGGATGAACGGCGCCGGCGCACCGCCCGCGGCGGGCGCCGCG
GCGCAGGTGAAGGGGCAGCC

Downstream 100 bases:

>100_bases
GCGGACCGCGCGGCTCGTGGACCCGCGCCCCGCCCCGGTCCCGTTCACGAGCGCTTCGGCGCGTGCGCCGCCTACGGCCG
GAACCCGGACCAGAGCACCT

Product: HflC protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MTRAAVVTAVLAVVAVFAVTASTYTLTENEQAVITRFGEPRGEPITEPGLHFKLPFADTVNRFDRRWLDWRGDPNQIPTK
DKKYIWVDTFGRWRIVDPLRFFQRLRDERNAQSRLDDIIDGETRNAIASFALIEAVRTTNRTFEDDEYSAELGGAEALET
VQAGRDRLTRQIRDRAAEVVKEFGVELVDVQIRRINYVNEVQVKVFDRMISERRRIAERSRSEGMGRAAEIRGQRERDLK
AIRSEAYRKAQEVSGKADAEATRIYAAAFGRDPEFFQFLRTLEAYPRTVDASTSLFLGTDTEFYRYLRSSKKQ

Sequences:

>Translated_313_residues
MTRAAVVTAVLAVVAVFAVTASTYTLTENEQAVITRFGEPRGEPITEPGLHFKLPFADTVNRFDRRWLDWRGDPNQIPTK
DKKYIWVDTFGRWRIVDPLRFFQRLRDERNAQSRLDDIIDGETRNAIASFALIEAVRTTNRTFEDDEYSAELGGAEALET
VQAGRDRLTRQIRDRAAEVVKEFGVELVDVQIRRINYVNEVQVKVFDRMISERRRIAERSRSEGMGRAAEIRGQRERDLK
AIRSEAYRKAQEVSGKADAEATRIYAAAFGRDPEFFQFLRTLEAYPRTVDASTSLFLGTDTEFYRYLRSSKKQ
>Mature_312_residues
TRAAVVTAVLAVVAVFAVTASTYTLTENEQAVITRFGEPRGEPITEPGLHFKLPFADTVNRFDRRWLDWRGDPNQIPTKD
KKYIWVDTFGRWRIVDPLRFFQRLRDERNAQSRLDDIIDGETRNAIASFALIEAVRTTNRTFEDDEYSAELGGAEALETV
QAGRDRLTRQIRDRAAEVVKEFGVELVDVQIRRINYVNEVQVKVFDRMISERRRIAERSRSEGMGRAAEIRGQRERDLKA
IRSEAYRKAQEVSGKADAEATRIYAAAFGRDPEFFQFLRTLEAYPRTVDASTSLFLGTDTEFYRYLRSSKKQ

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790617, Length=318, Percent_Identity=27.9874213836478, Blast_Score=131, Evalue=5e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010200 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: 3.4.-.-

Molecular weight: Translated: 36093; Mature: 35962

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRAAVVTAVLAVVAVFAVTASTYTLTENEQAVITRFGEPRGEPITEPGLHFKLPFADTV
CCHHHHHHHHHHHHHHHHHHHCEEEECCCCHHHHEECCCCCCCCCCCCCCEEECCCHHHH
NRFDRRWLDWRGDPNQIPTKDKKYIWVDTFGRWRIVDPLRFFQRLRDERNAQSRLDDIID
HHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCEEEECHHHHHHHHHHHHHHHHHHHHHHC
GETRNAIASFALIEAVRTTNRTFEDDEYSAELGGAEALETVQAGRDRLTRQIRDRAAEVV
CCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KEFGVELVDVQIRRINYVNEVQVKVFDRMISERRRIAERSRSEGMGRAAEIRGQRERDLK
HHHCCCEEEHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHH
AIRSEAYRKAQEVSGKADAEATRIYAAAFGRDPEFFQFLRTLEAYPRTVDASTSLFLGTD
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEECCC
TEFYRYLRSSKKQ
HHHHHHHHHCCCC
>Mature Secondary Structure 
TRAAVVTAVLAVVAVFAVTASTYTLTENEQAVITRFGEPRGEPITEPGLHFKLPFADTV
CHHHHHHHHHHHHHHHHHHHCEEEECCCCHHHHEECCCCCCCCCCCCCCEEECCCHHHH
NRFDRRWLDWRGDPNQIPTKDKKYIWVDTFGRWRIVDPLRFFQRLRDERNAQSRLDDIID
HHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCEEEECHHHHHHHHHHHHHHHHHHHHHHC
GETRNAIASFALIEAVRTTNRTFEDDEYSAELGGAEALETVQAGRDRLTRQIRDRAAEVV
CCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KEFGVELVDVQIRRINYVNEVQVKVFDRMISERRRIAERSRSEGMGRAAEIRGQRERDLK
HHHCCCEEEHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHH
AIRSEAYRKAQEVSGKADAEATRIYAAAFGRDPEFFQFLRTLEAYPRTVDASTSLFLGTD
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEECCC
TEFYRYLRSSKKQ
HHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]