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The map label for this gene is xerC [H]

Identifier: 220917980

GI number: 220917980

Start: 3181830

End: 3182861

Strand: Reverse

Name: xerC [H]

Synonym: A2cp1_2881

Alternate gene names: 220917980

Gene position: 3182861-3181830 (Counterclockwise)

Preceding gene: 220917981

Following gene: 220917979

Centisome position: 63.29

GC content: 78.68

Gene sequence:

>1032_bases
ATGACGCCCGACGCGTCCGCGCTGCCGCCCGAGGTGCCGGAGGAGATCCGGCGCTTCGACGCGTACCTCGCCTCGGAGAA
GCGGGCCTCGCCGCACACGCGCAAGGCGTACCAGGTGGACCTGGCCCAGTACGCGGCCTACCTCGCCGACCAGGGCCAGC
CGCTCGTGCCGTCCTCGCCCGCGCTGGTGCGCGGCTTCCTGGCGCGCCAGGCCGGGGCCGCCGGGGCGGTGAGCCTCGGC
CGCAAGCTCTCCGCGCTCCGCTCGCTGTACCGCTTCCTGGTGCGCGAGGGGCTCGCGCCCGGGAACCCGGCCCGCGCCGT
GGCGAGCCCGAAGCGGCCGAAGCGCCTGCCGGAGGTGCTGCCCGAGGAGGAGGTCGCGGCGCTGGTGGAGACGCCCGACG
CCGCCACGGAGGCGCCGCTCGCGCTGCGCGACCGCGCGTTCCTGGAGCTGCTCTACGGGAGCGGGCTGCGCGTCTCGGAG
CTGACGGGCCTGGACCTCGAGGACCTCGACCTCGCGGGCGGGCTGGTGCGCGTGCTCGGCAAGCGGAACAAGGAGCGCAT
CGTGCCGTTCGGCGCACCGGCCGCCGACGCGCTCCGGCGCTACCTCGACGGCGCGCGCCCGGTGCTGGCCGCGGGGCCGG
ACCACGCCCGCGCCGGGGACGCGGTGTTCCTGAACTTCCGCGGGGGCCGGCTCACCAGCCGCTCGGTGGCGCGCCGGCTG
GACGGCTGGGTGCTCGCCTCCGGCCTGCCGCGCCACGTGCACCCGCACGTGCTGCGCCACTGCTTCGCGACGCACCTGCT
CGGCAACGGCGCCGACCTGCGCGGCATCCAGGAGCTGCTCGGGCACGCGTCGCTCTCCACCACGCAGCGGTACACGCACC
TCGACTGGAAGCGGCTCGCGGCGGTCTACGACGCGGCCCACCCGCGCGCGCGGGCCGGGGCGGCGGGCGGCGCGGGCGCC
GGCGGACCCGGAGGCGACGTGCCCGGCGCGGCGCCCGGCCGCAGCGCCCGCGGCGGCCGCGGCCCGCGCTGA

Upstream 100 bases:

>100_bases
GAAGCGCCAGGGCGCCTACGTGGCCGAGCTGCCGCGCTAGCGCGGGGCCGGCGGCGCCAGGAACTGTCGCCCGGGCCGGC
GCGGTGGTACGCGATCCCCG

Downstream 100 bases:

>100_bases
CGCTCGGCGCGGGGCGGGCCGCCGTGAATCGTTGCCCCCCGGGCGCGGCCGCGCTACCTCTCGGGCATGCGCCCCATGCA
CGGAACGACCGTCCTCTGCG

Product: tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MTPDASALPPEVPEEIRRFDAYLASEKRASPHTRKAYQVDLAQYAAYLADQGQPLVPSSPALVRGFLARQAGAAGAVSLG
RKLSALRSLYRFLVREGLAPGNPARAVASPKRPKRLPEVLPEEEVAALVETPDAATEAPLALRDRAFLELLYGSGLRVSE
LTGLDLEDLDLAGGLVRVLGKRNKERIVPFGAPAADALRRYLDGARPVLAAGPDHARAGDAVFLNFRGGRLTSRSVARRL
DGWVLASGLPRHVHPHVLRHCFATHLLGNGADLRGIQELLGHASLSTTQRYTHLDWKRLAAVYDAAHPRARAGAAGGAGA
GGPGGDVPGAAPGRSARGGRGPR

Sequences:

>Translated_343_residues
MTPDASALPPEVPEEIRRFDAYLASEKRASPHTRKAYQVDLAQYAAYLADQGQPLVPSSPALVRGFLARQAGAAGAVSLG
RKLSALRSLYRFLVREGLAPGNPARAVASPKRPKRLPEVLPEEEVAALVETPDAATEAPLALRDRAFLELLYGSGLRVSE
LTGLDLEDLDLAGGLVRVLGKRNKERIVPFGAPAADALRRYLDGARPVLAAGPDHARAGDAVFLNFRGGRLTSRSVARRL
DGWVLASGLPRHVHPHVLRHCFATHLLGNGADLRGIQELLGHASLSTTQRYTHLDWKRLAAVYDAAHPRARAGAAGGAGA
GGPGGDVPGAAPGRSARGGRGPR
>Mature_342_residues
TPDASALPPEVPEEIRRFDAYLASEKRASPHTRKAYQVDLAQYAAYLADQGQPLVPSSPALVRGFLARQAGAAGAVSLGR
KLSALRSLYRFLVREGLAPGNPARAVASPKRPKRLPEVLPEEEVAALVETPDAATEAPLALRDRAFLELLYGSGLRVSEL
TGLDLEDLDLAGGLVRVLGKRNKERIVPFGAPAADALRRYLDGARPVLAAGPDHARAGDAVFLNFRGGRLTSRSVARRLD
GWVLASGLPRHVHPHVLRHCFATHLLGNGADLRGIQELLGHASLSTTQRYTHLDWKRLAAVYDAAHPRARAGAAGGAGAG
GPGGDVPGAAPGRSARGGRGPR

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4973

COG function: function code L; Site-specific recombinase XerC

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=306, Percent_Identity=43.7908496732026, Blast_Score=242, Evalue=3e-65,
Organism=Escherichia coli, GI1789261, Length=297, Percent_Identity=42.4242424242424, Blast_Score=214, Evalue=9e-57,
Organism=Escherichia coli, GI1790768, Length=186, Percent_Identity=31.1827956989247, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790767, Length=195, Percent_Identity=28.2051282051282, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 36309; Mature: 36178

Theoretical pI: Translated: 10.66; Mature: 10.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPDASALPPEVPEEIRRFDAYLASEKRASPHTRKAYQVDLAQYAAYLADQGQPLVPSSP
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCH
ALVRGFLARQAGAAGAVSLGRKLSALRSLYRFLVREGLAPGNPARAVASPKRPKRLPEVL
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCHHHHHHC
PEEEVAALVETPDAATEAPLALRDRAFLELLYGSGLRVSELTGLDLEDLDLAGGLVRVLG
CHHHHHHHHCCCCCHHCCCHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHC
KRNKERIVPFGAPAADALRRYLDGARPVLAAGPDHARAGDAVFLNFRGGRLTSRSVARRL
CCCCCCCCCCCCCHHHHHHHHHCCCCCEEECCCCCCCCCCEEEEEECCCCCHHHHHHHHH
DGWVLASGLPRHVHPHVLRHCFATHLLGNGADLRGIQELLGHASLSTTQRYTHLDWKRLA
CCCCEECCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHH
AVYDAAHPRARAGAAGGAGAGGPGGDVPGAAPGRSARGGRGPR
HHHHHCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TPDASALPPEVPEEIRRFDAYLASEKRASPHTRKAYQVDLAQYAAYLADQGQPLVPSSP
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCH
ALVRGFLARQAGAAGAVSLGRKLSALRSLYRFLVREGLAPGNPARAVASPKRPKRLPEVL
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCHHHHHHC
PEEEVAALVETPDAATEAPLALRDRAFLELLYGSGLRVSELTGLDLEDLDLAGGLVRVLG
CHHHHHHHHCCCCCHHCCCHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHC
KRNKERIVPFGAPAADALRRYLDGARPVLAAGPDHARAGDAVFLNFRGGRLTSRSVARRL
CCCCCCCCCCCCCHHHHHHHHHCCCCCEEECCCCCCCCCCEEEEEECCCCCHHHHHHHHH
DGWVLASGLPRHVHPHVLRHCFATHLLGNGADLRGIQELLGHASLSTTQRYTHLDWKRLA
CCCCEECCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHH
AVYDAAHPRARAGAAGGAGAGGPGGDVPGAAPGRSARGGRGPR
HHHHHCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12828649 [H]