Click here to switch to the map view.

The map label for this gene is hslV

Identifier: 220917979

GI number: 220917979

Start: 3181218

End: 3181763

Strand: Reverse

Name: hslV

Synonym: A2cp1_2880

Alternate gene names: 220917979

Gene position: 3181763-3181218 (Counterclockwise)

Preceding gene: 220917980

Following gene: 220917978

Centisome position: 63.26

GC content: 72.53

Gene sequence:

>546_bases
ATGCGCCCCATGCACGGAACGACCGTCCTCTGCGTGCGCCGAGAGGGCAGGGTGGTGATCGCCGGCGACGGCCAGGTCAC
CCTGGACAAGACCGTCATGAAGGCCACTGCCCGCAAGGTGCGGCGGCTGGGCGAGGGCCAGGTGGTGGCGGGGTTCGCCG
GCGCGACCGCCGACGCGTTCCAGCTCTTCGAGCTGTTCGAGAAGAAGCTGAAGGAGCACGCGCGCTCGCTCCCGCGGGCC
GCGGTGGAGCTCGCGAAGCAGTGGCGCACCGACCGGATGCTGCGCCGGCTCGAGGCGCTGCTGCTGGTGGCCGACCGCGA
GCACCTGCTGGTGCTGTCCGGCGCCGGTGACGTCATCGAGCCGGATCCGGTGGCGAACGGCGCGGCCGCGGCGATCGGGT
CCGGGGGCCCCTACGCGCTGGCCGCGGCGCGGGCGCTGCTCGCCCACTCGGCGCTGGACGCCCGCCAGGTGGCCGAGGAG
GCCATGAAGCTCGCCGCCGAGATCTGCATCTACACGAATGGCAACCTCACCATCGAGGAGCTGTGA

Upstream 100 bases:

>100_bases
CCGCAGCGCCCGCGGCGGCCGCGGCCCGCGCTGACGCTCGGCGCGGGGCGGGCCGCCGTGAATCGTTGCCCCCCGGGCGC
GGCCGCGCTACCTCTCGGGC

Downstream 100 bases:

>100_bases
TGGCGCCGAGCCCGAAGCCGCAGGACCTCACCCCGCGGGAGATCGTGGCGGAGCTGGACCGCTACGTGGTCGGCCAGGCG
CAGGCGAAGCGCGCGGTCGC

Product: ATP-dependent protease peptidase subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MRPMHGTTVLCVRREGRVVIAGDGQVTLDKTVMKATARKVRRLGEGQVVAGFAGATADAFQLFELFEKKLKEHARSLPRA
AVELAKQWRTDRMLRRLEALLLVADREHLLVLSGAGDVIEPDPVANGAAAAIGSGGPYALAAARALLAHSALDARQVAEE
AMKLAAEICIYTNGNLTIEEL

Sequences:

>Translated_181_residues
MRPMHGTTVLCVRREGRVVIAGDGQVTLDKTVMKATARKVRRLGEGQVVAGFAGATADAFQLFELFEKKLKEHARSLPRA
AVELAKQWRTDRMLRRLEALLLVADREHLLVLSGAGDVIEPDPVANGAAAAIGSGGPYALAAARALLAHSALDARQVAEE
AMKLAAEICIYTNGNLTIEEL
>Mature_181_residues
MRPMHGTTVLCVRREGRVVIAGDGQVTLDKTVMKATARKVRRLGEGQVVAGFAGATADAFQLFELFEKKLKEHARSLPRA
AVELAKQWRTDRMLRRLEALLLVADREHLLVLSGAGDVIEPDPVANGAAAAIGSGGPYALAAARALLAHSALDARQVAEE
AMKLAAEICIYTNGNLTIEEL

Specific function: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery

COG id: COG5405

COG function: function code O; ATP-dependent protease HslVU (ClpYQ), peptidase subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1B family. HslV subfamily

Homologues:

Organism=Escherichia coli, GI1790367, Length=175, Percent_Identity=62.2857142857143, Blast_Score=213, Evalue=8e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSLV_ANAD2 (B8JES1)

Other databases:

- EMBL:   CP001359
- RefSeq:   YP_002493283.1
- ProteinModelPortal:   B8JES1
- SMR:   B8JES1
- MEROPS:   T01.006
- GeneID:   7299811
- GenomeReviews:   CP001359_GR
- KEGG:   acp:A2cp1_2880
- HOGENOM:   HBG288822
- ProtClustDB:   PRK05456
- HAMAP:   MF_00248
- InterPro:   IPR022281
- InterPro:   IPR001353
- TIGRFAMs:   TIGR03692

Pfam domain/function: PF00227 Proteasome

EC number: 3.4.25.-

Molecular weight: Translated: 19409; Mature: 19409

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: NA

Important sites: ACT_SITE 7-7

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPMHGTTVLCVRREGRVVIAGDGQVTLDKTVMKATARKVRRLGEGQVVAGFAGATADAF
CCCCCCCEEEEEECCCEEEEECCCCEEHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHH
QLFELFEKKLKEHARSLPRAAVELAKQWRTDRMLRRLEALLLVADREHLLVLSGAGDVIE
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEECCCCCCC
PDPVANGAAAAIGSGGPYALAAARALLAHSALDARQVAEEAMKLAAEICIYTNGNLTIEE
CCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCEEEEE
L
C
>Mature Secondary Structure
MRPMHGTTVLCVRREGRVVIAGDGQVTLDKTVMKATARKVRRLGEGQVVAGFAGATADAF
CCCCCCCEEEEEECCCEEEEECCCCEEHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHH
QLFELFEKKLKEHARSLPRAAVELAKQWRTDRMLRRLEALLLVADREHLLVLSGAGDVIE
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEECCCCCCC
PDPVANGAAAAIGSGGPYALAAARALLAHSALDARQVAEEAMKLAAEICIYTNGNLTIEE
CCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCEEEEE
L
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA