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The map label for this gene is zraR [H]

Identifier: 220917726

GI number: 220917726

Start: 2901929

End: 2902651

Strand: Direct

Name: zraR [H]

Synonym: A2cp1_2627

Alternate gene names: 220917726

Gene position: 2901929-2902651 (Clockwise)

Preceding gene: 220917725

Following gene: 220917727

Centisome position: 57.7

GC content: 75.66

Gene sequence:

>723_bases
ATGCGCCGCTACCTCATCGTGGACGACAACCGCGACTTCGCGGAGAACCTGGCCGAGATCCTGCGCGACGCCGGCCACGA
GGTCGCGCTCGCCGGCGACGGCGCCGAGGCGCTGGCGCTCGCGCGCGGGACCCGCTTCGACGCCATCCTCACCGACATGC
GCATGCCGCTCATGGGCGGCGCCGAGCTCGTCCACGAGCTGCGCCGCGTGGACCCCGGCGCGCCGGCCATGGTCATCACC
GCCTACGTGGGCGACAACGACCTCGAGGCCGCGCGGCGCGAGGGGCTGGTGGCGGTGCTGCAGAAGCCGGTGAACGCCGC
CTACCTGGTGGAGCTGCTCGAGGTGGCCCGGCGCGACGGCCTGGCGGTGGTGGTGGAGGACGACCCCCGGCTCGCCGACA
ACCTCTGCGAGGCGCTGCGCTCGCGCGGCTTCGCCGCGGTGACCGCCGCGTCGGTGCTGGAGACCGAGCGGCTCGGGCCG
GTGCAGCCGTTCTGCGCGCTGGTGGACCTGCGCGTGCCCGGCGGTCCCGACGGCGCCGCCATGCAGCGCCTCGCCGCCAA
GTACCCCGCCCTGCCCATGATCGTCGTCACCGCCCACCACGACGCCTGGCCGGCGCTCCCGCACCAGGGCTTCTTCCACA
AGCCGTTCGACACCGCCTCGCTGCTCGCCGCGGTGGAGCGGCTCCACGGCGCCCGCGCCCCCTCGCCGGTGCCCGCCCCG
TGA

Upstream 100 bases:

>100_bases
GCATCGCCGAGCGCCACGGCGGCTCGGTCGAGTACTCGGACCGGCCCGGGGGCGGCGCGCGGTTCACCGTTCGCCTCCCC
GCCTGAGCGGAGGATCCCGC

Downstream 100 bases:

>100_bases
AGCACGGCGGCGGGCCGCGGCGGCCGCGCGTGCTGGTGGTGGACGACAACGCCAGCCTGGTGGACAACCTCTCCGAGATC
CTGGAGGGCGCCGGCTACGC

Product: response regulator receiver protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MRRYLIVDDNRDFAENLAEILRDAGHEVALAGDGAEALALARGTRFDAILTDMRMPLMGGAELVHELRRVDPGAPAMVIT
AYVGDNDLEAARREGLVAVLQKPVNAAYLVELLEVARRDGLAVVVEDDPRLADNLCEALRSRGFAAVTAASVLETERLGP
VQPFCALVDLRVPGGPDGAAMQRLAAKYPALPMIVVTAHHDAWPALPHQGFFHKPFDTASLLAAVERLHGARAPSPVPAP

Sequences:

>Translated_240_residues
MRRYLIVDDNRDFAENLAEILRDAGHEVALAGDGAEALALARGTRFDAILTDMRMPLMGGAELVHELRRVDPGAPAMVIT
AYVGDNDLEAARREGLVAVLQKPVNAAYLVELLEVARRDGLAVVVEDDPRLADNLCEALRSRGFAAVTAASVLETERLGP
VQPFCALVDLRVPGGPDGAAMQRLAAKYPALPMIVVTAHHDAWPALPHQGFFHKPFDTASLLAAVERLHGARAPSPVPAP
>Mature_240_residues
MRRYLIVDDNRDFAENLAEILRDAGHEVALAGDGAEALALARGTRFDAILTDMRMPLMGGAELVHELRRVDPGAPAMVIT
AYVGDNDLEAARREGLVAVLQKPVNAAYLVELLEVARRDGLAVVVEDDPRLADNLCEALRSRGFAAVTAASVLETERLGP
VQPFCALVDLRVPGGPDGAAMQRLAAKYPALPMIVVTAHHDAWPALPHQGFFHKPFDTASLLAAVERLHGARAPSPVPAP

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=112, Percent_Identity=34.8214285714286, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1788905, Length=110, Percent_Identity=32.7272727272727, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 25728; Mature: 25728

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRYLIVDDNRDFAENLAEILRDAGHEVALAGDGAEALALARGTRFDAILTDMRMPLMGG
CCEEEEEECCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHCCCHHHHHHHHHCCCCCCC
AELVHELRRVDPGAPAMVITAYVGDNDLEAARREGLVAVLQKPVNAAYLVELLEVARRDG
HHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHCCC
LAVVVEDDPRLADNLCEALRSRGFAAVTAASVLETERLGPVQPFCALVDLRVPGGPDGAA
CEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHEEEEECCCCCCHHH
MQRLAAKYPALPMIVVTAHHDAWPALPHQGFFHKPFDTASLLAAVERLHGARAPSPVPAP
HHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MRRYLIVDDNRDFAENLAEILRDAGHEVALAGDGAEALALARGTRFDAILTDMRMPLMGG
CCEEEEEECCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHCCCHHHHHHHHHCCCCCCC
AELVHELRRVDPGAPAMVITAYVGDNDLEAARREGLVAVLQKPVNAAYLVELLEVARRDG
HHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHHCCC
LAVVVEDDPRLADNLCEALRSRGFAAVTAASVLETERLGPVQPFCALVDLRVPGGPDGAA
CEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHEEEEECCCCCCHHH
MQRLAAKYPALPMIVVTAHHDAWPALPHQGFFHKPFDTASLLAAVERLHGARAPSPVPAP
HHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11243806 [H]