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The map label for this gene is atoS [H]

Identifier: 220917725

GI number: 220917725

Start: 2900775

End: 2901914

Strand: Direct

Name: atoS [H]

Synonym: A2cp1_2626

Alternate gene names: 220917725

Gene position: 2900775-2901914 (Clockwise)

Preceding gene: 220917724

Following gene: 220917726

Centisome position: 57.68

GC content: 73.25

Gene sequence:

>1140_bases
ATGCCCGAGACCGTGCTCGAGGAGCTGAAGCGCTACGTCCGCTTCGATGCCGGGGACGAGCGGGCGCTCCGCGCCCTCCA
CGGCGCGGCCGCGCCGCAGCTCGACCGGATCGCCCAGGTCTTCTACGACCGCATCCTCTCGCACGAGGGGGCGCGCACCG
CGCTGGTGGGGGGCGAGAGCCGGGTGGGTCACCTCAAGGTGACCCTGATCGGCTGGATGGACACGCTGCTCAGCGGTCCG
TGGGACGAGGGGTACTGGGAGCACCGGACCCGGATCGGCCGCGTCCACGTCCGCATCGGCCTGCCGCAGCACTACATGTT
CGGCGCGATGAACGTGATCCGCACCGAGCTGATGCGCGTCTCCTGGGAGCGCTTCAACGCGGACCCGCCCGAGCTGGAGC
GGGTGCGCAACGCGCTCGCGAAGATCCTCGATCTCGAGCTCGCCATCATGCTGCACACCTACCGCGACGACCTGCTCGCG
CAGCAGGCGCGGGTGGAGCGGCTCTCGACGTTCGGCCAGCTCGTCGGCTCCATCGGCCACGACCTGCGCAACCCGCTCGG
CGTCATCGAGACCTCGCTCTACATCCTGCGCGGGCGGGTGGGCGACGACGAGCGCGCCCGCAAGCACGTGGACCGCATCG
GCGAGCAGCTCGGCGTCGCGAACGGGATCATCACGAACCTGCTCGACATGATCCGCAACCGGCCGCTGGCGCGCGAGCCG
GTGGACGTCGGCCAGGTGGTCGCCGCCGCCGCGGCCGCGGTGAAGCACGCGCCGGGCGTGTCGGTCGCGGTGGAGGGCTT
CGAGGGGCTGCCGCCGGTGGACGGCGACCCGGGCCAGCTCCGCCAGGTGTTCGTGAACCTGCTCGAGAACGCGGCGTTCG
CGGCGGCGCCGCAGGGCGCGGTGACGGTCCGCGCGCGCCGCGACGACGGCGCGCTCGAGGTGGCGGTCGAGGACACCGGC
CCCGGCGTGGACCCCGCCACGCGCCGCCGCCTGTTCGAGCCGCTCATCACCACCAAGGACAAGGGCATCGGCCTGGGCCT
GGCGCTCGTGAAGCGCATCGCCGAGCGCCACGGCGGCTCGGTCGAGTACTCGGACCGGCCCGGGGGCGGCGCGCGGTTCA
CCGTTCGCCTCCCCGCCTGA

Upstream 100 bases:

>100_bases
CGGCCAGGCCTAGATCGCCCCTCATGTCCGGCCGCCCGCCGGCTCGCCCGGGGCAACGCGCGTTGACCGGCCGCCCGGGC
CCCCCTTACATAGGGGTCGA

Downstream 100 bases:

>100_bases
GCGGAGGATCCCGCATGCGCCGCTACCTCATCGTGGACGACAACCGCGACTTCGCGGAGAACCTGGCCGAGATCCTGCGC
GACGCCGGCCACGAGGTCGC

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 378

Protein sequence:

>379_residues
MPETVLEELKRYVRFDAGDERALRALHGAAAPQLDRIAQVFYDRILSHEGARTALVGGESRVGHLKVTLIGWMDTLLSGP
WDEGYWEHRTRIGRVHVRIGLPQHYMFGAMNVIRTELMRVSWERFNADPPELERVRNALAKILDLELAIMLHTYRDDLLA
QQARVERLSTFGQLVGSIGHDLRNPLGVIETSLYILRGRVGDDERARKHVDRIGEQLGVANGIITNLLDMIRNRPLAREP
VDVGQVVAAAAAAVKHAPGVSVAVEGFEGLPPVDGDPGQLRQVFVNLLENAAFAAAPQGAVTVRARRDDGALEVAVEDTG
PGVDPATRRRLFEPLITTKDKGIGLGLALVKRIAERHGGSVEYSDRPGGGARFTVRLPA

Sequences:

>Translated_379_residues
MPETVLEELKRYVRFDAGDERALRALHGAAAPQLDRIAQVFYDRILSHEGARTALVGGESRVGHLKVTLIGWMDTLLSGP
WDEGYWEHRTRIGRVHVRIGLPQHYMFGAMNVIRTELMRVSWERFNADPPELERVRNALAKILDLELAIMLHTYRDDLLA
QQARVERLSTFGQLVGSIGHDLRNPLGVIETSLYILRGRVGDDERARKHVDRIGEQLGVANGIITNLLDMIRNRPLAREP
VDVGQVVAAAAAAVKHAPGVSVAVEGFEGLPPVDGDPGQLRQVFVNLLENAAFAAAPQGAVTVRARRDDGALEVAVEDTG
PGVDPATRRRLFEPLITTKDKGIGLGLALVKRIAERHGGSVEYSDRPGGGARFTVRLPA
>Mature_378_residues
PETVLEELKRYVRFDAGDERALRALHGAAAPQLDRIAQVFYDRILSHEGARTALVGGESRVGHLKVTLIGWMDTLLSGPW
DEGYWEHRTRIGRVHVRIGLPQHYMFGAMNVIRTELMRVSWERFNADPPELERVRNALAKILDLELAIMLHTYRDDLLAQ
QARVERLSTFGQLVGSIGHDLRNPLGVIETSLYILRGRVGDDERARKHVDRIGEQLGVANGIITNLLDMIRNRPLAREPV
DVGQVVAAAAAAVKHAPGVSVAVEGFEGLPPVDGDPGQLRQVFVNLLENAAFAAAPQGAVTVRARRDDGALEVAVEDTGP
GVDPATRRRLFEPLITTKDKGIGLGLALVKRIAERHGGSVEYSDRPGGGARFTVRLPA

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=231, Percent_Identity=32.034632034632, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1790436, Length=250, Percent_Identity=28.8, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1790346, Length=227, Percent_Identity=31.2775330396476, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1786912, Length=231, Percent_Identity=30.3030303030303, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI87081816, Length=220, Percent_Identity=28.6363636363636, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI145693157, Length=235, Percent_Identity=28.0851063829787, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1790300, Length=218, Percent_Identity=27.0642201834862, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI48994928, Length=224, Percent_Identity=30.3571428571429, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786600, Length=250, Percent_Identity=28.4, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788393, Length=225, Percent_Identity=28.8888888888889, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1789808, Length=212, Percent_Identity=27.3584905660377, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790551, Length=109, Percent_Identity=39.4495412844037, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1790567, Length=239, Percent_Identity=26.3598326359833, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787374, Length=219, Percent_Identity=27.3972602739726, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 41620; Mature: 41489

Theoretical pI: Translated: 7.47; Mature: 7.47

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPETVLEELKRYVRFDAGDERALRALHGAAAPQLDRIAQVFYDRILSHEGARTALVGGES
CCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCC
RVGHLKVTLIGWMDTLLSGPWDEGYWEHRTRIGRVHVRIGLPQHYMFGAMNVIRTELMRV
CCCEEEEEHHHHHHHHHCCCCCCCHHHHHHHEEEEEEEECCCHHHHHHHHHHHHHHHHHH
SWERFNADPPELERVRNALAKILDLELAIMLHTYRDDLLAQQARVERLSTFGQLVGSIGH
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLRNPLGVIETSLYILRGRVGDDERARKHVDRIGEQLGVANGIITNLLDMIRNRPLAREP
HHHCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
VDVGQVVAAAAAAVKHAPGVSVAVEGFEGLPPVDGDPGQLRQVFVNLLENAAFAAAPQGA
CHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCHHHCCCCCC
VTVRARRDDGALEVAVEDTGPGVDPATRRRLFEPLITTKDKGIGLGLALVKRIAERHGGS
EEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCC
VEYSDRPGGGARFTVRLPA
EEECCCCCCCCEEEEECCC
>Mature Secondary Structure 
PETVLEELKRYVRFDAGDERALRALHGAAAPQLDRIAQVFYDRILSHEGARTALVGGES
CHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCC
RVGHLKVTLIGWMDTLLSGPWDEGYWEHRTRIGRVHVRIGLPQHYMFGAMNVIRTELMRV
CCCEEEEEHHHHHHHHHCCCCCCCHHHHHHHEEEEEEEECCCHHHHHHHHHHHHHHHHHH
SWERFNADPPELERVRNALAKILDLELAIMLHTYRDDLLAQQARVERLSTFGQLVGSIGH
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLRNPLGVIETSLYILRGRVGDDERARKHVDRIGEQLGVANGIITNLLDMIRNRPLAREP
HHHCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
VDVGQVVAAAAAAVKHAPGVSVAVEGFEGLPPVDGDPGQLRQVFVNLLENAAFAAAPQGA
CHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCHHHCCCCCC
VTVRARRDDGALEVAVEDTGPGVDPATRRRLFEPLITTKDKGIGLGLALVKRIAERHGGS
EEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCC
VEYSDRPGGGARFTVRLPA
EEECCCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]