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The map label for this gene is sstT [H]

Identifier: 220905418

GI number: 220905418

Start: 2600795

End: 2602000

Strand: Reverse

Name: sstT [H]

Synonym: Ddes_2156

Alternate gene names: 220905418

Gene position: 2602000-2600795 (Counterclockwise)

Preceding gene: 220905420

Following gene: 220905417

Centisome position: 90.55

GC content: 56.72

Gene sequence:

>1206_bases
ATGGCCAAGATTGGTGATATGGCGCTGGTGCTCAAACTGCTGGCTGGCCTGGTTGTGGGGGCCTTGCTTGGCTTTGTAGC
CAATGAGAGCGTCATGAACGTGGTGGTTTCGGTGCGTCACATTCTGGGGCAGATCATTTTCTTTCTCGTGCCTCTGGTTA
TTGTGGGCTTTATCACCCCTGCCATCATCCGCCTGGGGCAGCAGGCCAGTAAAATCCTGCTGGTGGCCGTGCTGCTGGCC
TACTCATCTTCTTTGGGGGCGGCGCTTTTTTCCACGTTTTCAGGCTATCTGATTATCCCGCATCTCACGGTGTCTTCTGC
CACAGAAACGCTGCGCACGCTGCCCCAGATGGTGTTTCAGCTTGATATTCCGCCGCTTTTCAGTGTTATGAGCGCCCTGA
CCCTGGCCCTGCTTTTCGGTCTGGGCGTGGCCCTGACACAATCGGAAACCATGAGCAGGCTTTTTGCCGAACTTGAAAAG
GTCGTCAGCTGGCTTATCAATAAGGTCATGATTCCCATCCTGCCTTTTTTCGTCGGTCTTTCGTTTATGGGGCTGGCCTA
TGAAGGCTCGCTTACCAGGCATCTGCCTGTATTTGTGTCTATGGTGGCCCTGGTCATCGTGGGGCAGTTTATCTGGCTTT
CGGTTCTTTACGGCATTGGCGGCCTTGTTTCCCGGCGGAACCCCTCGCAGGTTTTCCGGCACTATCTGCCCGCCTACCTC
ACGGCTGTGGGCACCATGTCCAGCGCGGCCACCCTGCCCGTGGCGCTGGAATGCGCCCGCCGTTCGCCTGTGCTCAGCCG
CACCATGGTGGAATTCATGATTCCTCTGGGGGCTACGGTGCATCTGTGCGGCTCTGTTCTGACAGAAACGTTCTTTGTCA
TGACCATCAGCCTTATACTTTACGGAACCCTGCCCTCCGTAGGGACCATGATTCTTTTCTGTGTGCTGCTCGGCATTTTT
GCTGTGGGGGCTCCCGGCGTTCCGGGCGGCACGGTTGTGGCTTCGCTTGGCATTGTTACAGGTGTTCTTGGTTTTGACGC
CACGGGCGTTGCCCTGCTTATCGCCATCTTTGCCTTGCAGGACAGCTTCGGCACGGCCTGCAACGTCACCGGCGACGGGG
CGCTGGCCCTTATTCTTGAAGGTGTTTTCAACGACAACGGGCAACTGGGAGCGTTGCAGGCACCGTCAATGACGGAGCAT
TCATGA

Upstream 100 bases:

>100_bases
TCTGGAGTCAGCGTGCAGAGGGTTACTGATCAGCATTTCCCCAACCTTGGAATACCGGGCTGTGACATGAGTACGCCCGA
AAACAGAGAGGGAGAAGGTA

Downstream 100 bases:

>100_bases
ATCAGAACTGGCAGTCATTTATAGATTTGTTGCATGAAGAAGTAGTACCCGCGCTCGGCTGCACAGAGCCTGTGGCAGTG
GCCCTTACCGCCGCACAGGC

Product: sodium:dicarboxylate symporter

Products: NA

Alternate protein names: Na(+)/serine-threonine symporter [H]

Number of amino acids: Translated: 401; Mature: 400

Protein sequence:

>401_residues
MAKIGDMALVLKLLAGLVVGALLGFVANESVMNVVVSVRHILGQIIFFLVPLVIVGFITPAIIRLGQQASKILLVAVLLA
YSSSLGAALFSTFSGYLIIPHLTVSSATETLRTLPQMVFQLDIPPLFSVMSALTLALLFGLGVALTQSETMSRLFAELEK
VVSWLINKVMIPILPFFVGLSFMGLAYEGSLTRHLPVFVSMVALVIVGQFIWLSVLYGIGGLVSRRNPSQVFRHYLPAYL
TAVGTMSSAATLPVALECARRSPVLSRTMVEFMIPLGATVHLCGSVLTETFFVMTISLILYGTLPSVGTMILFCVLLGIF
AVGAPGVPGGTVVASLGIVTGVLGFDATGVALLIAIFALQDSFGTACNVTGDGALALILEGVFNDNGQLGALQAPSMTEH
S

Sequences:

>Translated_401_residues
MAKIGDMALVLKLLAGLVVGALLGFVANESVMNVVVSVRHILGQIIFFLVPLVIVGFITPAIIRLGQQASKILLVAVLLA
YSSSLGAALFSTFSGYLIIPHLTVSSATETLRTLPQMVFQLDIPPLFSVMSALTLALLFGLGVALTQSETMSRLFAELEK
VVSWLINKVMIPILPFFVGLSFMGLAYEGSLTRHLPVFVSMVALVIVGQFIWLSVLYGIGGLVSRRNPSQVFRHYLPAYL
TAVGTMSSAATLPVALECARRSPVLSRTMVEFMIPLGATVHLCGSVLTETFFVMTISLILYGTLPSVGTMILFCVLLGIF
AVGAPGVPGGTVVASLGIVTGVLGFDATGVALLIAIFALQDSFGTACNVTGDGALALILEGVFNDNGQLGALQAPSMTEH
S
>Mature_400_residues
AKIGDMALVLKLLAGLVVGALLGFVANESVMNVVVSVRHILGQIIFFLVPLVIVGFITPAIIRLGQQASKILLVAVLLAY
SSSLGAALFSTFSGYLIIPHLTVSSATETLRTLPQMVFQLDIPPLFSVMSALTLALLFGLGVALTQSETMSRLFAELEKV
VSWLINKVMIPILPFFVGLSFMGLAYEGSLTRHLPVFVSMVALVIVGQFIWLSVLYGIGGLVSRRNPSQVFRHYLPAYLT
AVGTMSSAATLPVALECARRSPVLSRTMVEFMIPLGATVHLCGSVLTETFFVMTISLILYGTLPSVGTMILFCVLLGIFA
VGAPGVPGGTVVASLGIVTGVLGFDATGVALLIAIFALQDSFGTACNVTGDGALALILEGVFNDNGQLGALQAPSMTEHS

Specific function: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) [H]

COG id: COG1301

COG function: function code C; Na+/H+-dicarboxylate symporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family [H]

Homologues:

Organism=Homo sapiens, GI40254478, Length=151, Percent_Identity=32.4503311258278, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI169790839, Length=287, Percent_Identity=26.1324041811847, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI66773030, Length=155, Percent_Identity=32.9032258064516, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI4827012, Length=177, Percent_Identity=33.3333333333333, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI194239697, Length=183, Percent_Identity=30.6010928961749, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI21314632, Length=271, Percent_Identity=26.9372693726937, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI223468564, Length=151, Percent_Identity=30.4635761589404, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI223468566, Length=151, Percent_Identity=30.4635761589404, Blast_Score=67, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71996953, Length=268, Percent_Identity=27.9850746268657, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71983106, Length=243, Percent_Identity=27.9835390946502, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71983099, Length=243, Percent_Identity=27.9835390946502, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17537407, Length=230, Percent_Identity=29.5652173913043, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI193206505, Length=151, Percent_Identity=30.4635761589404, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193206654, Length=164, Percent_Identity=27.4390243902439, Blast_Score=68, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17541374, Length=151, Percent_Identity=30.4635761589404, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001991
- InterPro:   IPR023025 [H]

Pfam domain/function: PF00375 SDF [H]

EC number: NA

Molecular weight: Translated: 42224; Mature: 42093

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HCCCCEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AKIGDMALVLKLLAGLVVGALLGFVANESVMNVVVSVRHILGQIIFFLVPLVIVGFITP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIIRLGQQASKILLVAVLLAYSSSLGAALFSTFSGYLIIPHLTVSSATETLRTLPQMVFQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHH
LDIPPLFSVMSALTLALLFGLGVALTQSETMSRLFAELEKVVSWLINKVMIPILPFFVGL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SFMGLAYEGSLTRHLPVFVSMVALVIVGQFIWLSVLYGIGGLVSRRNPSQVFRHYLPAYL
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
TAVGTMSSAATLPVALECARRSPVLSRTMVEFMIPLGATVHLCGSVLTETFFVMTISLIL
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
YGTLPSVGTMILFCVLLGIFAVGAPGVPGGTVVASLGIVTGVLGFDATGVALLIAIFALQ
HHCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
DSFGTACNVTGDGALALILEGVFNDNGQLGALQAPSMTEHS
HCCCCEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA