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The map label for this gene is sugE [H]

Identifier: 220905420

GI number: 220905420

Start: 2602378

End: 2602692

Strand: Reverse

Name: sugE [H]

Synonym: Ddes_2158

Alternate gene names: 220905420

Gene position: 2602692-2602378 (Counterclockwise)

Preceding gene: 220905421

Following gene: 220905418

Centisome position: 90.58

GC content: 56.83

Gene sequence:

>315_bases
ATGGCCTGGATTTTTTTGTTTTTTGCCGGTCTTCTTGAGGTTGTGTGGGCATACACTATGAAGCTGTCCGCCGGATTCAC
CAAGCCGCTTCCTTCCGTGCTCACCATTGTGGCCATGATTGCCAGCTTCGGTCTGCTGGCCGTAGCCATGAAAAGTCTGC
CTCTGGGTACGGCCTACACCATCTGGACAGGCATCGGTGCTGTGGGGGCCTTTGTGCTCGGCATCATGGTGCTGGGCGAA
CCTGTAAGCGCCATGCGCGTGGGCGCGGCTGCCCTTATTGTGACCGGCCTTGTGCTCATGAAGCTTTCTTCCTGA

Upstream 100 bases:

>100_bases
CTGGAACGGCGGCCTTATATCCAGATACAGGGAGGACGACCTCCCCCCATCAGGGGCATCTGATCCGGGACGACCCGGCT
CTGAAAAAAAGGAGAGCCGA

Downstream 100 bases:

>100_bases
GGCCGGGTCCAGCCCGCAATCAGGGCCTGTTTGCCACGTCCTGCTCTGCCTTGGTGCCGCCTTCCTGCCACCGCAGCAGG
AAAAAGCACCGGACAGCAGT

Product: small multidrug resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 104; Mature: 103

Protein sequence:

>104_residues
MAWIFLFFAGLLEVVWAYTMKLSAGFTKPLPSVLTIVAMIASFGLLAVAMKSLPLGTAYTIWTGIGAVGAFVLGIMVLGE
PVSAMRVGAAALIVTGLVLMKLSS

Sequences:

>Translated_104_residues
MAWIFLFFAGLLEVVWAYTMKLSAGFTKPLPSVLTIVAMIASFGLLAVAMKSLPLGTAYTIWTGIGAVGAFVLGIMVLGE
PVSAMRVGAAALIVTGLVLMKLSS
>Mature_103_residues
AWIFLFFAGLLEVVWAYTMKLSAGFTKPLPSVLTIVAMIASFGLLAVAMKSLPLGTAYTIWTGIGAVGAFVLGIMVLGEP
VSAMRVGAAALIVTGLVLMKLSS

Specific function: Quaternary ammonium compound efflux pump. Confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. SugE (TC 2.A.7.1.4) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082378, Length=104, Percent_Identity=58.6538461538462, Blast_Score=116, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 10823; Mature: 10692

Theoretical pI: Translated: 10.24; Mature: 10.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.7 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWIFLFFAGLLEVVWAYTMKLSAGFTKPLPSVLTIVAMIASFGLLAVAMKSLPLGTAYT
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
IWTGIGAVGAFVLGIMVLGEPVSAMRVGAAALIVTGLVLMKLSS
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AWIFLFFAGLLEVVWAYTMKLSAGFTKPLPSVLTIVAMIASFGLLAVAMKSLPLGTAYT
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
IWTGIGAVGAFVLGIMVLGEPVSAMRVGAAALIVTGLVLMKLSS
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]