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The map label for this gene is trxB [H]

Identifier: 220904470

GI number: 220904470

Start: 1411482

End: 1412408

Strand: Direct

Name: trxB [H]

Synonym: Ddes_1200

Alternate gene names: 220904470

Gene position: 1411482-1412408 (Clockwise)

Preceding gene: 220904469

Following gene: 220904471

Centisome position: 49.12

GC content: 55.88

Gene sequence:

>927_bases
ATGAAAGCATACGATGCCGTTGTGATCGGTGGCGGCCCCGCCGGCGTTACCGCAGCCCTGTATCTGGCGCGGTCCGGTTG
CAGCGTTCTTATGCCGGAGCGTTTGACCTCCGGGGGGCAGTTGCTGCAAACCGAAGCGCTGGAGAACTACCCGGGCTTTC
CCAAGGGCATCAAGGGCTATGAACTTGCCGACCTCTTCGCCGCGCATCTTGATGGTTTGGCAGTAGACAGGCCCGCCACC
GTTGTTGAATCCATTACCGGCTTGGCGGGCCGGTTTACTGTGCGCACTTCTGATGGGGAGCATACGTGCAAGACCGTGCT
GGTATGCTCGGGGGCCAAGCACCGTCAGTTGGGCCTTGAAGATGAAGACAGGTTGCGTGGCAAAGGAGTTTCCTACTGCG
CACTTTGCGACGGTAATTTTTATCGCAACCAGACTGTGGCCGTGGTGGGTGGCGGCAACGCCGCAATGGAAGAAAGCCTC
TATCTTACCAAAATAGTAGGCAAGCTTCATCTCATCCATCGGCGTGACAGTTTCCGGGGTCTCAAGGTATACGAAGACAG
GCTCGAAAGCATGCCGGACAAGGTCAACATCATACGCAGCTCGACTATTACGAAACTGCATGGTGAGGATTTTTTAACCG
GACTGACCGTAAAAAACCTCTTGAGCGGCCAGGAAGAACTGCTGCCTGTTGACGGGCTGTTCGTTTATGTGGGCTTTGCT
CCGGTAACGGACTTTCTGCCGCAGGGCATCGTGCTTGATGAGCAGGGCTTTATCGTGACAGATACTGAAATGCGTACCAG
TATTCCCGGCATTTTTGCCGCCGGAGACATACGCTCAAAGCTTTGCCGCCAGGTCATCACTGCCGCCGGCGATGGCGCAA
CCGCCGCTCAAGCGGCATTTGTCTTTCTGGAACAGCTCCATGCATAA

Upstream 100 bases:

>100_bases
CCACCCTCGTCCTTTTCAAAAACGGCGAAACTGTCGAGCAGATCACCGGCGCTGTGACCAAGGCTGCCATGAAAGATCTG
CTTGATACCAAGGCGCTGGC

Downstream 100 bases:

>100_bases
AAAATTGTTACGCTCCATCTTGCTTGTCATGAGCATGCTCATGGCTTCCGGCTGCGGTATTATTGATATGATATACCTGC
CGCCTGCCGAAGACACTGCG

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MKAYDAVVIGGGPAGVTAALYLARSGCSVLMPERLTSGGQLLQTEALENYPGFPKGIKGYELADLFAAHLDGLAVDRPAT
VVESITGLAGRFTVRTSDGEHTCKTVLVCSGAKHRQLGLEDEDRLRGKGVSYCALCDGNFYRNQTVAVVGGGNAAMEESL
YLTKIVGKLHLIHRRDSFRGLKVYEDRLESMPDKVNIIRSSTITKLHGEDFLTGLTVKNLLSGQEELLPVDGLFVYVGFA
PVTDFLPQGIVLDEQGFIVTDTEMRTSIPGIFAAGDIRSKLCRQVITAAGDGATAAQAAFVFLEQLHA

Sequences:

>Translated_308_residues
MKAYDAVVIGGGPAGVTAALYLARSGCSVLMPERLTSGGQLLQTEALENYPGFPKGIKGYELADLFAAHLDGLAVDRPAT
VVESITGLAGRFTVRTSDGEHTCKTVLVCSGAKHRQLGLEDEDRLRGKGVSYCALCDGNFYRNQTVAVVGGGNAAMEESL
YLTKIVGKLHLIHRRDSFRGLKVYEDRLESMPDKVNIIRSSTITKLHGEDFLTGLTVKNLLSGQEELLPVDGLFVYVGFA
PVTDFLPQGIVLDEQGFIVTDTEMRTSIPGIFAAGDIRSKLCRQVITAAGDGATAAQAAFVFLEQLHA
>Mature_308_residues
MKAYDAVVIGGGPAGVTAALYLARSGCSVLMPERLTSGGQLLQTEALENYPGFPKGIKGYELADLFAAHLDGLAVDRPAT
VVESITGLAGRFTVRTSDGEHTCKTVLVCSGAKHRQLGLEDEDRLRGKGVSYCALCDGNFYRNQTVAVVGGGNAAMEESL
YLTKIVGKLHLIHRRDSFRGLKVYEDRLESMPDKVNIIRSSTITKLHGEDFLTGLTVKNLLSGQEELLPVDGLFVYVGFA
PVTDFLPQGIVLDEQGFIVTDTEMRTSIPGIFAAGDIRSKLCRQVITAAGDGATAAQAAFVFLEQLHA

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=309, Percent_Identity=38.5113268608414, Blast_Score=203, Evalue=1e-53,
Organism=Escherichia coli, GI87081763, Length=308, Percent_Identity=34.7402597402597, Blast_Score=158, Evalue=5e-40,
Organism=Saccharomyces cerevisiae, GI6320560, Length=314, Percent_Identity=34.3949044585987, Blast_Score=176, Evalue=6e-45,
Organism=Saccharomyces cerevisiae, GI6321898, Length=315, Percent_Identity=32.6984126984127, Blast_Score=172, Evalue=8e-44,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 33012; Mature: 33012

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAYDAVVIGGGPAGVTAALYLARSGCSVLMPERLTSGGQLLQTEALENYPGFPKGIKGY
CCCCEEEEECCCCHHHHHHHHHHHCCCCEECCHHHCCCCCEEEHHHHHCCCCCCCCCCCC
ELADLFAAHLDGLAVDRPATVVESITGLAGRFTVRTSDGEHTCKTVLVCSGAKHRQLGLE
HHHHHHHHHHCCCCCCCHHHHHHHHHCCCEEEEEEECCCCCCEEEEEEECCCCCCCCCCC
DEDRLRGKGVSYCALCDGNFYRNQTVAVVGGGNAAMEESLYLTKIVGKLHLIHRRDSFRG
CHHHHCCCCCCEEEEECCCEECCCEEEEEECCCHHHHHHHHHHHHHHHHHEEECCCCCCC
LKVYEDRLESMPDKVNIIRSSTITKLHGEDFLTGLTVKNLLSGQEELLPVDGLFVYVGFA
HHHHHHHHHCCCCCEEEEHHCCEEEECCCHHHHHHHHHHHHCCHHHCCCCCCEEEEEEHH
PVTDFLPQGIVLDEQGFIVTDTEMRTSIPGIFAAGDIRSKLCRQVITAAGDGATAAQAAF
HHHHHCCCCEEECCCCCEEECCHHHHCCCCEEECCHHHHHHHHHHHHCCCCCCHHHHHHH
VFLEQLHA
HHHHHHCC
>Mature Secondary Structure
MKAYDAVVIGGGPAGVTAALYLARSGCSVLMPERLTSGGQLLQTEALENYPGFPKGIKGY
CCCCEEEEECCCCHHHHHHHHHHHCCCCEECCHHHCCCCCEEEHHHHHCCCCCCCCCCCC
ELADLFAAHLDGLAVDRPATVVESITGLAGRFTVRTSDGEHTCKTVLVCSGAKHRQLGLE
HHHHHHHHHHCCCCCCCHHHHHHHHHCCCEEEEEEECCCCCCEEEEEEECCCCCCCCCCC
DEDRLRGKGVSYCALCDGNFYRNQTVAVVGGGNAAMEESLYLTKIVGKLHLIHRRDSFRG
CHHHHCCCCCCEEEEECCCEECCCEEEEEECCCHHHHHHHHHHHHHHHHHEEECCCCCCC
LKVYEDRLESMPDKVNIIRSSTITKLHGEDFLTGLTVKNLLSGQEELLPVDGLFVYVGFA
HHHHHHHHHCCCCCEEEEHHCCEEEECCCHHHHHHHHHHHHCCHHHCCCCCCEEEEEEHH
PVTDFLPQGIVLDEQGFIVTDTEMRTSIPGIFAAGDIRSKLCRQVITAAGDGATAAQAAF
HHHHHCCCCEEECCCCCEEECCHHHHCCCCEEECCHHHHHHHHHHHHCCCCCCHHHHHHH
VFLEQLHA
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]