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The map label for this gene is gcp

Identifier: 220904468

GI number: 220904468

Start: 1409937

End: 1411022

Strand: Direct

Name: gcp

Synonym: Ddes_1198

Alternate gene names: 220904468

Gene position: 1409937-1411022 (Clockwise)

Preceding gene: 220904467

Following gene: 220904469

Centisome position: 49.07

GC content: 57.09

Gene sequence:

>1086_bases
ATGCTTTGCCTTGGCATTGAAAGTTCCTGTGACGAAACCGCGCTGGCCTTGGTGGAAGATGGCCGCCTGCTGCATTCTGT
ATTGTCCACCCAGGCTGATATGCACGCACTGTTTGGCGGTGTTGTGCCCGAGCTGGCATCCCGCGAGCATTATCGTTATA
TCGGCCCCCTGTTTGACGAATTGATGCGGCGTAGCGACAAGAGTAATGAAGAAATCGACCTTGTAGCTGTCGCGCGTGGG
CCGGGGCTGCTTGGCAGTCTGCTGGTGGGTGTGGCCTTTGCCAAGGGGCTTGCTTTCAGTCTGGGGGCACGTTTTCTCGG
TGTCAATCATTTACAGGCGCATCTACTGGCAGCCGGGCTGGAGCAACCTTTGAAGTTTCCGGCTTTGGGACTGCTGGTTT
CCGGCGGGCATACGCACCTGTATCGCATGGAAACCCCGTGGAACTGTCTGCCCCTTGGGCGCACCTTGGACGACGCGGCG
GGAGAGGCCTTTGACAAGGTCGGTAAGGTGCTTGGCCTGGCCTATCCAGGAGGACGCCTTATGGACGCTCTTGCCGGAGA
AGGGCGGGCGGATGGAATTGCCTTTCCACGTCCCTATCTGGACAATGACAACCTGGATTTCAGCTTCAGCGGATTGAAAA
CTGCCGCCAGTACCTATGTACAACAACATTTTGCGGGCATGACATGGCCGCGCCCTTTGGGTTCGACGGCGGCCGCGCCG
CAAGAACTGAAAGATTGTTGCGCCGCCTTTAATCTGGCCGTGGTGGATACCCTTTGCACAAAGGCTACGAGAGCACTGGA
CAGAAATCCGCAGTTGAAATATTTGATTCTTGCGGGCGGCGTTGCCTGCAACTCGTTGTTGCGCCAGCGCGTTACGGAAC
TGATGGAGCGCAGAGGCGGTCAGGCCATCATTCCCGGCCCGCATTTATGCACGGACAATGCGGCCATGATTGCCTATGCG
GGCTGGTTGCTCGGAAAAGAAGGATATTACCACCAATTAAACATGGAAACCGTACCCCGCGGGCGCGCCCTGCCTGACGA
TATGAGGCGCTGCCGGGAATACGCTGAAGACCTGTCAGAAACATGA

Upstream 100 bases:

>100_bases
TTATGCCAAGTATGCCGGTTTGATAGCCTGACAGCAAATCGTACGTAATTCTGGGGCCGCGTTCGGCGCGGCTCCTGTTT
TTTGTTGAAAGAGAGACCAT

Downstream 100 bases:

>100_bases
GATTGTCTTGACAGTCAGGTCTTTGGAAACTACTCTTGCTCAATACAGAGGCCTCGGAATCCATATCCCGAAGCTTCGGT
TTTCCGCCTCTGCGCCCTTT

Product: metalloendopeptidase, glycoprotease family

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MLCLGIESSCDETALALVEDGRLLHSVLSTQADMHALFGGVVPELASREHYRYIGPLFDELMRRSDKSNEEIDLVAVARG
PGLLGSLLVGVAFAKGLAFSLGARFLGVNHLQAHLLAAGLEQPLKFPALGLLVSGGHTHLYRMETPWNCLPLGRTLDDAA
GEAFDKVGKVLGLAYPGGRLMDALAGEGRADGIAFPRPYLDNDNLDFSFSGLKTAASTYVQQHFAGMTWPRPLGSTAAAP
QELKDCCAAFNLAVVDTLCTKATRALDRNPQLKYLILAGGVACNSLLRQRVTELMERRGGQAIIPGPHLCTDNAAMIAYA
GWLLGKEGYYHQLNMETVPRGRALPDDMRRCREYAEDLSET

Sequences:

>Translated_361_residues
MLCLGIESSCDETALALVEDGRLLHSVLSTQADMHALFGGVVPELASREHYRYIGPLFDELMRRSDKSNEEIDLVAVARG
PGLLGSLLVGVAFAKGLAFSLGARFLGVNHLQAHLLAAGLEQPLKFPALGLLVSGGHTHLYRMETPWNCLPLGRTLDDAA
GEAFDKVGKVLGLAYPGGRLMDALAGEGRADGIAFPRPYLDNDNLDFSFSGLKTAASTYVQQHFAGMTWPRPLGSTAAAP
QELKDCCAAFNLAVVDTLCTKATRALDRNPQLKYLILAGGVACNSLLRQRVTELMERRGGQAIIPGPHLCTDNAAMIAYA
GWLLGKEGYYHQLNMETVPRGRALPDDMRRCREYAEDLSET
>Mature_361_residues
MLCLGIESSCDETALALVEDGRLLHSVLSTQADMHALFGGVVPELASREHYRYIGPLFDELMRRSDKSNEEIDLVAVARG
PGLLGSLLVGVAFAKGLAFSLGARFLGVNHLQAHLLAAGLEQPLKFPALGLLVSGGHTHLYRMETPWNCLPLGRTLDDAA
GEAFDKVGKVLGLAYPGGRLMDALAGEGRADGIAFPRPYLDNDNLDFSFSGLKTAASTYVQQHFAGMTWPRPLGSTAAAP
QELKDCCAAFNLAVVDTLCTKATRALDRNPQLKYLILAGGVACNSLLRQRVTELMERRGGQAIIPGPHLCTDNAAMIAYA
GWLLGKEGYYHQLNMETVPRGRALPDDMRRCREYAEDLSET

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI116812636, Length=335, Percent_Identity=31.9402985074627, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI8923380, Length=342, Percent_Identity=28.3625730994152, Blast_Score=101, Evalue=1e-21,
Organism=Escherichia coli, GI1789445, Length=342, Percent_Identity=45.0292397660819, Blast_Score=269, Evalue=2e-73,
Organism=Caenorhabditis elegans, GI17557464, Length=335, Percent_Identity=28.0597014925373, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71995670, Length=347, Percent_Identity=28.2420749279539, Blast_Score=100, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6320099, Length=350, Percent_Identity=30.2857142857143, Blast_Score=120, Evalue=4e-28,
Organism=Saccharomyces cerevisiae, GI6322891, Length=324, Percent_Identity=25, Blast_Score=73, Evalue=7e-14,
Organism=Drosophila melanogaster, GI20129063, Length=339, Percent_Identity=34.5132743362832, Blast_Score=164, Evalue=8e-41,
Organism=Drosophila melanogaster, GI21357207, Length=339, Percent_Identity=25.9587020648968, Blast_Score=104, Evalue=9e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_DESDA (B8J025)

Other databases:

- EMBL:   CP001358
- RefSeq:   YP_002479780.1
- MEROPS:   M22.001
- GeneID:   7284880
- GenomeReviews:   CP001358_GR
- KEGG:   dds:Ddes_1198
- HOGENOM:   HBG304663
- ProtClustDB:   PRK09604
- GO:   GO:0006508
- HAMAP:   MF_01445
- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03723
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 39041; Mature: 39041

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLCLGIESSCDETALALVEDGRLLHSVLSTQADMHALFGGVVPELASREHYRYIGPLFDE
CEEECCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LMRRSDKSNEEIDLVAVARGPGLLGSLLVGVAFAKGLAFSLGARFLGVNHLQAHLLAAGL
HHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQPLKFPALGLLVSGGHTHLYRMETPWNCLPLGRTLDDAAGEAFDKVGKVLGLAYPGGRL
HCCCCCCCCEEEEECCCEEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCCCHHH
MDALAGEGRADGIAFPRPYLDNDNLDFSFSGLKTAASTYVQQHFAGMTWPRPLGSTAAAP
HHHHCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCH
QELKDCCAAFNLAVVDTLCTKATRALDRNPQLKYLILAGGVACNSLLRQRVTELMERRGG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCC
QAIIPGPHLCTDNAAMIAYAGWLLGKEGYYHQLNMETVPRGRALPDDMRRCREYAEDLSE
CEECCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHCC
T
C
>Mature Secondary Structure
MLCLGIESSCDETALALVEDGRLLHSVLSTQADMHALFGGVVPELASREHYRYIGPLFDE
CEEECCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LMRRSDKSNEEIDLVAVARGPGLLGSLLVGVAFAKGLAFSLGARFLGVNHLQAHLLAAGL
HHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQPLKFPALGLLVSGGHTHLYRMETPWNCLPLGRTLDDAAGEAFDKVGKVLGLAYPGGRL
HCCCCCCCCEEEEECCCEEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCCCHHH
MDALAGEGRADGIAFPRPYLDNDNLDFSFSGLKTAASTYVQQHFAGMTWPRPLGSTAAAP
HHHHCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCH
QELKDCCAAFNLAVVDTLCTKATRALDRNPQLKYLILAGGVACNSLLRQRVTELMERRGG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCC
QAIIPGPHLCTDNAAMIAYAGWLLGKEGYYHQLNMETVPRGRALPDDMRRCREYAEDLSE
CEECCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHCC
T
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA