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The map label for this gene is murM.1 [H]

Identifier: 21909971

GI number: 21909971

Start: 477753

End: 478979

Strand: Reverse

Name: murM.1 [H]

Synonym: SpyM3_0435

Alternate gene names: 21909971

Gene position: 478979-477753 (Counterclockwise)

Preceding gene: 21909972

Following gene: 21909970

Centisome position: 25.2

GC content: 39.53

Gene sequence:

>1227_bases
ATGTATACATATAAAATCGGAATATCTCCTGAAGAACATGATCAGTTTGTCTTAGCACAGCCACAAGCTGGCTTACTTCA
AAGTTCAAAGTGGGGAAAAGTCAAAGATAACTGGAAACACGAACGCATCAGCTTTTATGAAAATGGGGTACAAGTTGCTG
CTGCTGCTTGTTTAATCAGAAAACTTCCTCTTGGTTTCACTATGATTTATATCCCACGTGGGCCAATCATGGACTACGCC
AATTTTGAACTCCTTGATTTCGTTATTAAAACGCTCAAAACGTTCGGAAAAAGCAAACGAGCGCTTTTTGTCAAAATTGA
TCCAAGTTTAGTCATCAAACAAACTTTAGAAGGAAAAGAAAGCAAAGAAAATGATGTGACACTCTCTATTATTGCTTTTC
TAAAAAAACTTGGTGTCGAATGGTCTGGCAGAACAAAAGAACTCGAAGACACTATTCAACCAAGAATACAAGCCAACATC
TACGCCAAGGATTTTGACTTTGACAGCCTGCCCAAAAAAGCCAAGCAATCCATTCGTACCGCTACCAATAAAGGTGTTAA
TGTCACGATTGGTGGCAGTGAATTGCTAGACGACTTTTCAGCCTTGATGAAAAAAACCGAGAATCGAAAAGGCATTATCC
TTCGAGGCAAATCCTACTATCAAAAATTACTAGGTATTTATGCTGGTCAGTCCTACATTACTATGGCTAGTTTAGACTTA
CCTGAACAAAAAAAACTCTTGATCCAACAGTTGGACAAAGCCTTAGCAGAACAAGCACGATTAACAGATAAGAGTAAACC
TAGCAAAGTAGCAGAAAATCAAAAAACCATTGCACGGCTACAAAAAGATTTAACCATTTTAAGCGAGCAGCTCGCTGCAG
GCAAAACCCGCATCCCACTAGCCGCCACCCTAACCTTGATTTATGGCGAGTCTTCTGAAAATCTTTATGCGGGAATGGAC
GATAATTATCGCAATTATCAAGCTCCTCTTTTAACCTGGTATGAAACGGCTAAAGAAGCTTTTAAAAGAGGCTGCCGCTG
GCATAATTTAGGAGGCGTGGAAAATCAACAAGATGGTGGACTCTATCATTTCAAAGCTAGACTCAACCCCACCATCGAAG
AATTTACAGGTGAATTCAACATTCCTGTCGGCCTTGTTTCAAGCTTAGCCATCTTGACCTATAACTTAAGAAAAAAATTA
AGGAGCACAACTAATGGCACTAATTGA

Upstream 100 bases:

>100_bases
AAAATGGGGTTCCTGAATTGAAAAAAATAGCCAAATACATCACCAAATCCAACAATGACAGTGGTGTGGCACATGCTATT
CGCAAGTGGGTATTAAACTA

Downstream 100 bases:

>100_bases
AATTTCACAAGAACAATTTGACCATTACTGCCACAGTCTCGTCCGTCATTCCTTTATCCAAACCTCAGAAATGGCCAGCT
TGATGGCTAAAAGAGGGGCA

Product: putative peptidoglycan branched peptide synthesis protein, serine/alanine adding enzyme

Products: NA

Alternate protein names: Factor essential for expression of methicillin resistance X [H]

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MYTYKIGISPEEHDQFVLAQPQAGLLQSSKWGKVKDNWKHERISFYENGVQVAAAACLIRKLPLGFTMIYIPRGPIMDYA
NFELLDFVIKTLKTFGKSKRALFVKIDPSLVIKQTLEGKESKENDVTLSIIAFLKKLGVEWSGRTKELEDTIQPRIQANI
YAKDFDFDSLPKKAKQSIRTATNKGVNVTIGGSELLDDFSALMKKTENRKGIILRGKSYYQKLLGIYAGQSYITMASLDL
PEQKKLLIQQLDKALAEQARLTDKSKPSKVAENQKTIARLQKDLTILSEQLAAGKTRIPLAATLTLIYGESSENLYAGMD
DNYRNYQAPLLTWYETAKEAFKRGCRWHNLGGVENQQDGGLYHFKARLNPTIEEFTGEFNIPVGLVSSLAILTYNLRKKL
RSTTNGTN

Sequences:

>Translated_408_residues
MYTYKIGISPEEHDQFVLAQPQAGLLQSSKWGKVKDNWKHERISFYENGVQVAAAACLIRKLPLGFTMIYIPRGPIMDYA
NFELLDFVIKTLKTFGKSKRALFVKIDPSLVIKQTLEGKESKENDVTLSIIAFLKKLGVEWSGRTKELEDTIQPRIQANI
YAKDFDFDSLPKKAKQSIRTATNKGVNVTIGGSELLDDFSALMKKTENRKGIILRGKSYYQKLLGIYAGQSYITMASLDL
PEQKKLLIQQLDKALAEQARLTDKSKPSKVAENQKTIARLQKDLTILSEQLAAGKTRIPLAATLTLIYGESSENLYAGMD
DNYRNYQAPLLTWYETAKEAFKRGCRWHNLGGVENQQDGGLYHFKARLNPTIEEFTGEFNIPVGLVSSLAILTYNLRKKL
RSTTNGTN
>Mature_408_residues
MYTYKIGISPEEHDQFVLAQPQAGLLQSSKWGKVKDNWKHERISFYENGVQVAAAACLIRKLPLGFTMIYIPRGPIMDYA
NFELLDFVIKTLKTFGKSKRALFVKIDPSLVIKQTLEGKESKENDVTLSIIAFLKKLGVEWSGRTKELEDTIQPRIQANI
YAKDFDFDSLPKKAKQSIRTATNKGVNVTIGGSELLDDFSALMKKTENRKGIILRGKSYYQKLLGIYAGQSYITMASLDL
PEQKKLLIQQLDKALAEQARLTDKSKPSKVAENQKTIARLQKDLTILSEQLAAGKTRIPLAATLTLIYGESSENLYAGMD
DNYRNYQAPLLTWYETAKEAFKRGCRWHNLGGVENQQDGGLYHFKARLNPTIEEFTGEFNIPVGLVSSLAILTYNLRKKL
RSTTNGTN

Specific function: Catalyzes the incorporation of the first glycine of the pentaglycine interpeptide bridge, which is characteristic of the S.aureus peptidoglycan. This glycine is added to the epsilon-amino group of the L-lysine of the membrane-bound lipid II intermediate (

COG id: COG2348

COG function: function code V; Uncharacterized protein involved in methicillin resistance

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the femABX family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016181
- InterPro:   IPR003447 [H]

Pfam domain/function: PF02388 FemAB [H]

EC number: NA

Molecular weight: Translated: 45994; Mature: 45994

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYTYKIGISPEEHDQFVLAQPQAGLLQSSKWGKVKDNWKHERISFYENGVQVAAAACLIR
CEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHH
KLPLGFTMIYIPRGPIMDYANFELLDFVIKTLKTFGKSKRALFVKIDPSLVIKQTLEGKE
HCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHCCCC
SKENDVTLSIIAFLKKLGVEWSGRTKELEDTIQPRIQANIYAKDFDFDSLPKKAKQSIRT
CCCCCEEHHHHHHHHHHCCCCCCCCHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHH
ATNKGVNVTIGGSELLDDFSALMKKTENRKGIILRGKSYYQKLLGIYAGQSYITMASLDL
HCCCCCEEEECHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHCCCCEEEEEECCC
PEQKKLLIQQLDKALAEQARLTDKSKPSKVAENQKTIARLQKDLTILSEQLAAGKTRIPL
CHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
AATLTLIYGESSENLYAGMDDNYRNYQAPLLTWYETAKEAFKRGCRWHNLGGVENQQDGG
EEEEEEEECCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
LYHFKARLNPTIEEFTGEFNIPVGLVSSLAILTYNLRKKLRSTTNGTN
EEEEEECCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MYTYKIGISPEEHDQFVLAQPQAGLLQSSKWGKVKDNWKHERISFYENGVQVAAAACLIR
CEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHH
KLPLGFTMIYIPRGPIMDYANFELLDFVIKTLKTFGKSKRALFVKIDPSLVIKQTLEGKE
HCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHCCCC
SKENDVTLSIIAFLKKLGVEWSGRTKELEDTIQPRIQANIYAKDFDFDSLPKKAKQSIRT
CCCCCEEHHHHHHHHHHCCCCCCCCHHHHHHHCCCEEEEEEEECCCCCCCCHHHHHHHHH
ATNKGVNVTIGGSELLDDFSALMKKTENRKGIILRGKSYYQKLLGIYAGQSYITMASLDL
HCCCCCEEEECHHHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHCCCCEEEEEECCC
PEQKKLLIQQLDKALAEQARLTDKSKPSKVAENQKTIARLQKDLTILSEQLAAGKTRIPL
CHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
AATLTLIYGESSENLYAGMDDNYRNYQAPLLTWYETAKEAFKRGCRWHNLGGVENQQDGG
EEEEEEEECCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
LYHFKARLNPTIEEFTGEFNIPVGLVSSLAILTYNLRKKLRSTTNGTN
EEEEEECCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA