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The map label for this gene is ysgA [C]

Identifier: 218930789

GI number: 218930789

Start: 4251211

End: 4252014

Strand: Direct

Name: ysgA [C]

Synonym: YPO3787

Alternate gene names: 218930789

Gene position: 4251211-4252014 (Clockwise)

Preceding gene: 218930774

Following gene: 218930791

Centisome position: 91.35

GC content: 49.38

Gene sequence:

>804_bases
ATGGCAACGGCCCACCATACTGACCAACTACATTCGTTACAAACCCACGGTATTCACTGTGGGGAAACAACGATCCCCTC
TCAGGGTGATGAGCTACCCGCTTATATTGCTAAACCTGACCAACATACAGGGCCATACCCTGTGGTGATTGTCGTGCAAG
AAATCTTTGGCGTGCATGAACATATTCAGGATATCTGCCGCCGGCTCGCCAAACAGGGCTATTTAGCCATAGCGCCCGAA
TTGTATTTTCGTCAGGGCGATGCCAAAGACTATAGTAATATTAATGAGTTAGTGAATAATCTGGTAAAAAAAGTCCCTGA
TCGTCAGGTTTTGGTGGATCTCGATCACACCGCTCATTGGGCATCCCGCCACGGTGGGGACACCAAAAAATTGGCCATTA
CCGGATTTTGCTGGGGCGGGCGTATCGCATGGTTATATGCCGCACATAATCCACAGTTGAAGGCGGCCGTGGCCTGGTAT
GGCAAATTGGTTGGTGAAAAAACCTTATTCCTACCGAAATATCCGGTCGATGTTGCTATCGATCTCTGCGCCCCAGTGTT
GGGGCTATATGGAGGTAAAGACACCAGTATCCCAGCAGAGCATATTGAAACTATGCGCCAGGCATTACGCGCTGCGAATG
CCGATGCTGAGATTATTGTTTATCCAGAGGCTGGGCATGCTTTTAATGCCGACTATCGCCCAAGCTATCATGCAGAGTCG
GCCCAAGATGGCTGGCAACGTATGCTTGATTGGTTTACCCAACATGGTGTCTCGGCCATCCCCATTCCAGAAGAAACGCA
ATAA

Upstream 100 bases:

>100_bases
AACACGTCCTCATATCGTAAGGAGATCACTTGTGAAAACGGATCAACTGGTTAGACTCAGACAAGCAGCGGGCGGTTTCA
CACCCGCCGGAACCCCATTA

Downstream 100 bases:

>100_bases
AAAAGGGCGCGAAAGCGCCCCAAAAGCCCCACTACACAGAGTAAAACGGTTTAATTAAACCTGTTCTTCACGCAGACGCT
GCGCTGCCAGCACCATATTC

Product: putative carboxymethylenebutenolidase

Products: NA

Alternate protein names: Dienelactone hydrolase; DLH

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MATAHHTDQLHSLQTHGIHCGETTIPSQGDELPAYIAKPDQHTGPYPVVIVVQEIFGVHEHIQDICRRLAKQGYLAIAPE
LYFRQGDAKDYSNINELVNNLVKKVPDRQVLVDLDHTAHWASRHGGDTKKLAITGFCWGGRIAWLYAAHNPQLKAAVAWY
GKLVGEKTLFLPKYPVDVAIDLCAPVLGLYGGKDTSIPAEHIETMRQALRAANADAEIIVYPEAGHAFNADYRPSYHAES
AQDGWQRMLDWFTQHGVSAIPIPEETQ

Sequences:

>Translated_267_residues
MATAHHTDQLHSLQTHGIHCGETTIPSQGDELPAYIAKPDQHTGPYPVVIVVQEIFGVHEHIQDICRRLAKQGYLAIAPE
LYFRQGDAKDYSNINELVNNLVKKVPDRQVLVDLDHTAHWASRHGGDTKKLAITGFCWGGRIAWLYAAHNPQLKAAVAWY
GKLVGEKTLFLPKYPVDVAIDLCAPVLGLYGGKDTSIPAEHIETMRQALRAANADAEIIVYPEAGHAFNADYRPSYHAES
AQDGWQRMLDWFTQHGVSAIPIPEETQ
>Mature_266_residues
ATAHHTDQLHSLQTHGIHCGETTIPSQGDELPAYIAKPDQHTGPYPVVIVVQEIFGVHEHIQDICRRLAKQGYLAIAPEL
YFRQGDAKDYSNINELVNNLVKKVPDRQVLVDLDHTAHWASRHGGDTKKLAITGFCWGGRIAWLYAAHNPQLKAAVAWYG
KLVGEKTLFLPKYPVDVAIDLCAPVLGLYGGKDTSIPAEHIETMRQALRAANADAEIIVYPEAGHAFNADYRPSYHAESA
QDGWQRMLDWFTQHGVSAIPIPEETQ

Specific function: Unknown

COG id: COG0412

COG function: function code Q; Dienelactone hydrolase and related enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dienelactone hydrolase family

Homologues:

Organism=Escherichia coli, GI48994982, Length=239, Percent_Identity=75.3138075313807, Blast_Score=386, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI17532655, Length=225, Percent_Identity=25.3333333333333, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DLHH_YERPE (Q8ZAL4)

Other databases:

- EMBL:   AL590842
- EMBL:   AE009952
- EMBL:   AE017042
- PIR:   AB0461
- RefSeq:   NP_667781.1
- RefSeq:   NP_994553.1
- RefSeq:   YP_002348664.1
- ProteinModelPortal:   Q8ZAL4
- GeneID:   1145390
- GeneID:   1176621
- GeneID:   2763578
- GenomeReviews:   AE009952_GR
- GenomeReviews:   AE017042_GR
- GenomeReviews:   AL590842_GR
- KEGG:   ype:YPO3787
- KEGG:   ypk:y0443
- KEGG:   ypm:YP_3262
- HOGENOM:   HBG673102
- OMA:   VHEHIAD
- ProtClustDB:   CLSK880795
- BioCyc:   YPES187410:Y0443-MONOMER
- BioCyc:   YPES214092:YPO3787-MONOMER
- BRENDA:   3.1.1.45
- InterPro:   IPR002925

Pfam domain/function: PF01738 DLH

EC number: =3.1.1.45

Molecular weight: Translated: 29671; Mature: 29540

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: ACT_SITE 137-137 ACT_SITE 194-194 ACT_SITE 226-226

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATAHHTDQLHSLQTHGIHCGETTIPSQGDELPAYIAKPDQHTGPYPVVIVVQEIFGVHE
CCCCCCHHHHHHHHHCCEECCCCCCCCCCCCCCCEEECCCCCCCCCEEEEHHHHHHHHHH
HIQDICRRLAKQGYLAIAPELYFRQGDAKDYSNINELVNNLVKKVPDRQVLVDLDHTAHW
HHHHHHHHHHHCCCEEECCHHHEECCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCHHHH
ASRHGGDTKKLAITGFCWGGRIAWLYAAHNPQLKAAVAWYGKLVGEKTLFLPKYPVDVAI
HHHCCCCCCEEEEEEEEECCEEEEEEECCCCCHHHHHHHHHHHHCCCEEECCCCCHHHHH
DLCAPVLGLYGGKDTSIPAEHIETMRQALRAANADAEIIVYPEAGHAFNADYRPSYHAES
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCH
AQDGWQRMLDWFTQHGVSAIPIPEETQ
HHHHHHHHHHHHHHCCCEECCCCCCCC
>Mature Secondary Structure 
ATAHHTDQLHSLQTHGIHCGETTIPSQGDELPAYIAKPDQHTGPYPVVIVVQEIFGVHE
CCCCCHHHHHHHHHCCEECCCCCCCCCCCCCCCEEECCCCCCCCCEEEEHHHHHHHHHH
HIQDICRRLAKQGYLAIAPELYFRQGDAKDYSNINELVNNLVKKVPDRQVLVDLDHTAHW
HHHHHHHHHHHCCCEEECCHHHEECCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCHHHH
ASRHGGDTKKLAITGFCWGGRIAWLYAAHNPQLKAAVAWYGKLVGEKTLFLPKYPVDVAI
HHHCCCCCCEEEEEEEEECCEEEEEEECCCCCHHHHHHHHHHHHCCCEEECCCCCHHHHH
DLCAPVLGLYGGKDTSIPAEHIETMRQALRAANADAEIIVYPEAGHAFNADYRPSYHAES
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCCH
AQDGWQRMLDWFTQHGVSAIPIPEETQ
HHHHHHHHHHHHHHCCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430