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The map label for this gene is iscR [H]

Identifier: 218929956

GI number: 218929956

Start: 3240230

End: 3240724

Strand: Reverse

Name: iscR [H]

Synonym: YPO2897

Alternate gene names: 218929956

Gene position: 3240724-3240230 (Counterclockwise)

Preceding gene: 218929957

Following gene: 218929955

Centisome position: 69.64

GC content: 52.32

Gene sequence:

>495_bases
ATGAGACTGACATCCAAAGGCCGCTATGCCGTAACCGCCATGCTTGATGTGGCATTACATTCCCAGGACGGGCCCGTTCC
TCTGGCAGATATTTCGGAACGTCAGGGGATCTCGTTATCCTATCTGGAACAACTTTTTTCACGCCTACGTAAAAATGGCT
TAGTCGCCAGCGTACGCGGCCCAGGCGGTGGTTATCTGCTGGGCAAAGATGCATCAGCAATCGCGGTTGGCGCGGTTATC
ACTGCCGTTGACGAATCCGTTGATGCAACCCGTTGTCAGGGTAAAGAAGGCTGTCAGGGCGGAAATCGCTGCCTGACACA
TACCCTGTGGCGTGATTTGAGCGAGCGTATCAGCAGCTTCCTCAACAATATTACATTGGCAGAACTGGTTAATAACCAAG
ATATCCTAGAGGTAGCGGATCGTCAGAATAACGATACGCGCCGCACGGCTAATGGCCGACCGCAAGAGACGATTAACGTC
AATCTGCGCGCATAA

Upstream 100 bases:

>100_bases
TGGTGATAATAGTTGAGTGAATTACTAGGTTAAATAGTTGACTAAAACACTCAAGAATGTCAAAATTCTGTTTCGTGTTC
ACCAACAGGTAACTTTAGCT

Downstream 100 bases:

>100_bases
GCAGAATTTGCGGAATTTTACGTTTTGGAAGTGATGTACGGAGCATAAGAGCAATGACCGAATCAAAAGTAAAGACACCG
ATCTATCTGGATTATGCAGC

Product: DNA-binding transcriptional regulator IscR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 164; Mature: 164

Protein sequence:

>164_residues
MRLTSKGRYAVTAMLDVALHSQDGPVPLADISERQGISLSYLEQLFSRLRKNGLVASVRGPGGGYLLGKDASAIAVGAVI
TAVDESVDATRCQGKEGCQGGNRCLTHTLWRDLSERISSFLNNITLAELVNNQDILEVADRQNNDTRRTANGRPQETINV
NLRA

Sequences:

>Translated_164_residues
MRLTSKGRYAVTAMLDVALHSQDGPVPLADISERQGISLSYLEQLFSRLRKNGLVASVRGPGGGYLLGKDASAIAVGAVI
TAVDESVDATRCQGKEGCQGGNRCLTHTLWRDLSERISSFLNNITLAELVNNQDILEVADRQNNDTRRTANGRPQETINV
NLRA
>Mature_164_residues
MRLTSKGRYAVTAMLDVALHSQDGPVPLADISERQGISLSYLEQLFSRLRKNGLVASVRGPGGGYLLGKDASAIAVGAVI
TAVDESVDATRCQGKEGCQGGNRCLTHTLWRDLSERISSFLNNITLAELVNNQDILEVADRQNNDTRRTANGRPQETINV
NLRA

Specific function: Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins [H]

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788880, Length=165, Percent_Identity=79.3939393939394, Blast_Score=236, Evalue=4e-64,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010242
- InterPro:   IPR000944
- InterPro:   IPR011991 [H]

Pfam domain/function: PF02082 Rrf2 [H]

EC number: NA

Molecular weight: Translated: 17765; Mature: 17765

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: PS01332 UPF0074

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLTSKGRYAVTAMLDVALHSQDGPVPLADISERQGISLSYLEQLFSRLRKNGLVASVRG
CCCCCCCCEEHHHHHHHHHCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEC
PGGGYLLGKDASAIAVGAVITAVDESVDATRCQGKEGCQGGNRCLTHTLWRDLSERISSF
CCCCEEECCCCCHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LNNITLAELVNNQDILEVADRQNNDTRRTANGRPQETINVNLRA
HHCCHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEC
>Mature Secondary Structure
MRLTSKGRYAVTAMLDVALHSQDGPVPLADISERQGISLSYLEQLFSRLRKNGLVASVRG
CCCCCCCCEEHHHHHHHHHCCCCCCCCHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEC
PGGGYLLGKDASAIAVGAVITAVDESVDATRCQGKEGCQGGNRCLTHTLWRDLSERISSF
CCCCEEECCCCCHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
LNNITLAELVNNQDILEVADRQNNDTRRTANGRPQETINVNLRA
HHCCHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA