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The map label for this gene is asd [H]

Identifier: 218929837

GI number: 218929837

Start: 3099152

End: 3100162

Strand: Direct

Name: asd [H]

Synonym: YPO2765

Alternate gene names: 218929837

Gene position: 3099152-3100162 (Clockwise)

Preceding gene: 218929835

Following gene: 218929838

Centisome position: 66.6

GC content: 53.31

Gene sequence:

>1011_bases
ATGTCTGACGGCTGGAATATTGCTCTATTAGGGGCAACGGGCGCAGTAGGTGAAGCTTTGCTGGAGCTGTTAAATGAGCG
CCAGTTCCCAGTTGGTGAATTGTATCCTTTGGCGAGCGAGCGCAGTGCCGGTGCTACTGTACGTTTTAACGGTAAAAGTA
TACTGGTTGAGAATGTGGCTGAATTTGACTGGTCCCAGGCTCAACTCGCCTTCTTTGTCGCAGGCCGTGAAGCATCGGCA
CAATATGCGGAAGAGGCTGGGAATGCCGGTTGTCTGGTGATCGACAGTAGCGGCTTGTTCGCTATGGAACCCGATATTCC
CTTGGTGGTGCCGAGCGTCAATCCTCAGGTGCTGGCTGATTACCGTAATCGTAATATCGTGGCGGTAGCCGATAGCCTGA
CCAGCCAGTTGCTGACGGCGATTAAACCGCTGACAGAACAGGCGGGGCTGTCTCGCCTGCATGTGACTAACCTGATTTCA
GCCTCAGCACATGGCAAAGCGGCGGTGGACGATCTCGCTGGGCAAAGTGCCAAGCTGCTCAATGGCATTCCTGCGGAACC
GGGTATCTTCCCTAAGCAATTGGCGTTTAACGTTTTACCGCTGCTGGCCGATGAAGAGGGCAGTGTGAGCGAAGAGCGCC
GTCTGGTTGATCAGGTGCGTAAAGTATTACAGGACGAAGGCTTGCCGATCACCGTAAGCTGCATTCAGTCACCGGTATTT
TATGGCCATGCGCAAGTGGTTCATCTGGAGGCATTGCGCCCGATCGCTGCCGAAGAAGCTCGTAGCGAACTGGAAAATTG
TGACGATATCCAATTGTCCGAAGAAGATGATTATCCAACCCAGGTCAGCGACGCCTCCGGCAGCGATGCCCTGAGTATTG
GTTGCGTTCGCAACGATTATGGTATTCCTGAAGTGCTGCAATTCTGGTCGGTGGCTGACAACATTCGTTTTGGTGGCGCA
TTGATGGCGATTCAAACGGCAGAGCGCCTGTTACAGGAGCAACTATACTGA

Upstream 100 bases:

>100_bases
AATAACGTCATGTTATTCAATAATTTAATCATTATTTAATGAGCTCATATCATTCAGTGAACTCATATTATTCCAATGAA
CTATAGCGGAGAAAACCAAC

Downstream 100 bases:

>100_bases
TGTCCGGGTTTGAATTAGATCAGGAAGAAACATTAGTTCAGCAAAACACATTGGCTCAGCAAGAAAAACCGGCAGAAGTG
GCCGGTTTGAAAATTGCGTT

Product: putative semialdehyde dehydrogenase

Products: L-4-aspartyl phosphate; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MSDGWNIALLGATGAVGEALLELLNERQFPVGELYPLASERSAGATVRFNGKSILVENVAEFDWSQAQLAFFVAGREASA
QYAEEAGNAGCLVIDSSGLFAMEPDIPLVVPSVNPQVLADYRNRNIVAVADSLTSQLLTAIKPLTEQAGLSRLHVTNLIS
ASAHGKAAVDDLAGQSAKLLNGIPAEPGIFPKQLAFNVLPLLADEEGSVSEERRLVDQVRKVLQDEGLPITVSCIQSPVF
YGHAQVVHLEALRPIAAEEARSELENCDDIQLSEEDDYPTQVSDASGSDALSIGCVRNDYGIPEVLQFWSVADNIRFGGA
LMAIQTAERLLQEQLY

Sequences:

>Translated_336_residues
MSDGWNIALLGATGAVGEALLELLNERQFPVGELYPLASERSAGATVRFNGKSILVENVAEFDWSQAQLAFFVAGREASA
QYAEEAGNAGCLVIDSSGLFAMEPDIPLVVPSVNPQVLADYRNRNIVAVADSLTSQLLTAIKPLTEQAGLSRLHVTNLIS
ASAHGKAAVDDLAGQSAKLLNGIPAEPGIFPKQLAFNVLPLLADEEGSVSEERRLVDQVRKVLQDEGLPITVSCIQSPVF
YGHAQVVHLEALRPIAAEEARSELENCDDIQLSEEDDYPTQVSDASGSDALSIGCVRNDYGIPEVLQFWSVADNIRFGGA
LMAIQTAERLLQEQLY
>Mature_335_residues
SDGWNIALLGATGAVGEALLELLNERQFPVGELYPLASERSAGATVRFNGKSILVENVAEFDWSQAQLAFFVAGREASAQ
YAEEAGNAGCLVIDSSGLFAMEPDIPLVVPSVNPQVLADYRNRNIVAVADSLTSQLLTAIKPLTEQAGLSRLHVTNLISA
SAHGKAAVDDLAGQSAKLLNGIPAEPGIFPKQLAFNVLPLLADEEGSVSEERRLVDQVRKVLQDEGLPITVSCIQSPVFY
GHAQVVHLEALRPIAAEEARSELENCDDIQLSEEDDYPTQVSDASGSDALSIGCVRNDYGIPEVLQFWSVADNIRFGGAL
MAIQTAERLLQEQLY

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=337, Percent_Identity=71.8100890207715, Blast_Score=499, Evalue=1e-143,
Organism=Saccharomyces cerevisiae, GI6320362, Length=387, Percent_Identity=25.5813953488372, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012080
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: 1.2.1.11

Molecular weight: Translated: 36060; Mature: 35929

Theoretical pI: Translated: 4.08; Mature: 4.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDGWNIALLGATGAVGEALLELLNERQFPVGELYPLASERSAGATVRFNGKSILVENVA
CCCCCEEEEEECCCHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCCEEEECCCEEEEHHHH
EFDWSQAQLAFFVAGREASAQYAEEAGNAGCLVIDSSGLFAMEPDIPLVVPSVNPQVLAD
HCCCCCCEEEEEEECCCHHHHHHHHCCCCCEEEEECCCEEEECCCCCEEECCCCHHHHHH
YRNRNIVAVADSLTSQLLTAIKPLTEQAGLSRLHVTNLISASAHGKAAVDDLAGQSAKLL
CCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHCCCCHHHH
NGIPAEPGIFPKQLAFNVLPLLADEEGSVSEERRLVDQVRKVLQDEGLPITVSCIQSPVF
CCCCCCCCCCHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEHHHHCCCCE
YGHAQVVHLEALRPIAAEEARSELENCDDIQLSEEDDYPTQVSDASGSDALSIGCVRNDY
ECCEEEEEEHHHCCHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCEEEEEEECCC
GIPEVLQFWSVADNIRFGGALMAIQTAERLLQEQLY
CCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SDGWNIALLGATGAVGEALLELLNERQFPVGELYPLASERSAGATVRFNGKSILVENVA
CCCCEEEEEECCCHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCCEEEECCCEEEEHHHH
EFDWSQAQLAFFVAGREASAQYAEEAGNAGCLVIDSSGLFAMEPDIPLVVPSVNPQVLAD
HCCCCCCEEEEEEECCCHHHHHHHHCCCCCEEEEECCCEEEECCCCCEEECCCCHHHHHH
YRNRNIVAVADSLTSQLLTAIKPLTEQAGLSRLHVTNLISASAHGKAAVDDLAGQSAKLL
CCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHCCCCHHHH
NGIPAEPGIFPKQLAFNVLPLLADEEGSVSEERRLVDQVRKVLQDEGLPITVSCIQSPVF
CCCCCCCCCCHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHCCCCEEHHHHCCCCE
YGHAQVVHLEALRPIAAEEARSELENCDDIQLSEEDDYPTQVSDASGSDALSIGCVRNDY
ECCEEEEEEHHHCCHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCEEEEEEECCC
GIPEVLQFWSVADNIRFGGALMAIQTAERLLQEQLY
CCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate 4-semialdehyde; phosphate; NADP+

Specific reaction: L-aspartate 4-semialdehyde + phosphate + NADP+ = L-4-aspartyl phosphate + NADPH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2991861; 9205837; 9278503; 3029016; 2681152 [H]