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The map label for this gene is nagD [H]

Identifier: 218929705

GI number: 218929705

Start: 2948967

End: 2949719

Strand: Reverse

Name: nagD [H]

Synonym: YPO2624

Alternate gene names: 218929705

Gene position: 2949719-2948967 (Counterclockwise)

Preceding gene: 218929706

Following gene: 218929704

Centisome position: 63.38

GC content: 49.27

Gene sequence:

>753_bases
ATGACAATCAAAAGCGTTATTTGCGATATCGATGGGGTGTTATTACATGACAACACCGCCATTAAGGGCGCCAATGACTT
TTTAGCCCGTATTCAGGATGCTGGAATGCCATTGGTGATCCTAACCAACTACCCATCCCAGACGGCGCAAGATCTGACTA
ACCGCTTTATCACTGCCGGGCTTGATGTGCCGGAAAGCGCGTTTTATACCTCAGCCATGGCAACGGCCGACTTTTTACGC
CGTCAGGATGGCAAAAAAGCCTATGTTATTGGCGAGGGTGCTTTAGTTCACGAACTCTATAAAGCTGGCTTTACCATCAC
CGATATCAATCCTGATTTTGTTATTGTCGGTGAGACGCGTTCTTATAACTGGGACATGATGCATAAAGCAGCCTATTTTG
TTGCCAATGGTGCACGTTTTATTGCCACTAACCCGGACAGCCACGGCCACGGCTTCGCCCCAGCCTGTGGTGCTCTGTGC
GCACCTATTGAAAAAATATCAGGCCGCAAACCGTTTTATGTCGGTAAGCCAAGTCCATGGATCATCCGTGCGGCGCTGAA
TAAAATGCAGGCGCATTCCGAAAGCACCGTGATTGTCGGCGATAACTTACGTACTGATATTTTAGCGGGCTTCCAGGCCG
GTCTGGAGACGATTCTGGTCTTATCCGGTGTCTCAACCCTTACTGATATCGACGCCATGCCGTTCCGTCCAAGCTACGTT
TACCCCTCGGTTGCCGACATCGATATTATCTAA

Upstream 100 bases:

>100_bases
GCAACGTTTGCTAGAAACTCACCCGTAGGTTGAAAGAAACTGTCATGGTCACAGCCATGTTATAGTGACCTATTGCCGCG
CTAAATGAGTAATATAAACA

Downstream 100 bases:

>100_bases
GATCTACTGGCGGTTACGGCCGCCACGCTTTTTTGGCCTAATTCCCCTTTTTAGTGCAGTGCACCAAATTCTCTTGCCAT
CACGCCCCATTTTGGCGCAC

Product: UMP phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MTIKSVICDIDGVLLHDNTAIKGANDFLARIQDAGMPLVILTNYPSQTAQDLTNRFITAGLDVPESAFYTSAMATADFLR
RQDGKKAYVIGEGALVHELYKAGFTITDINPDFVIVGETRSYNWDMMHKAAYFVANGARFIATNPDSHGHGFAPACGALC
APIEKISGRKPFYVGKPSPWIIRAALNKMQAHSESTVIVGDNLRTDILAGFQAGLETILVLSGVSTLTDIDAMPFRPSYV
YPSVADIDII

Sequences:

>Translated_250_residues
MTIKSVICDIDGVLLHDNTAIKGANDFLARIQDAGMPLVILTNYPSQTAQDLTNRFITAGLDVPESAFYTSAMATADFLR
RQDGKKAYVIGEGALVHELYKAGFTITDINPDFVIVGETRSYNWDMMHKAAYFVANGARFIATNPDSHGHGFAPACGALC
APIEKISGRKPFYVGKPSPWIIRAALNKMQAHSESTVIVGDNLRTDILAGFQAGLETILVLSGVSTLTDIDAMPFRPSYV
YPSVADIDII
>Mature_249_residues
TIKSVICDIDGVLLHDNTAIKGANDFLARIQDAGMPLVILTNYPSQTAQDLTNRFITAGLDVPESAFYTSAMATADFLRR
QDGKKAYVIGEGALVHELYKAGFTITDINPDFVIVGETRSYNWDMMHKAAYFVANGARFIATNPDSHGHGFAPACGALCA
PIEKISGRKPFYVGKPSPWIIRAALNKMQAHSESTVIVGDNLRTDILAGFQAGLETILVLSGVSTLTDIDAMPFRPSYVY
PSVADIDII

Specific function: Unknown

COG id: COG0647

COG function: function code G; Predicted sugar phosphatases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI10092677, Length=273, Percent_Identity=29.6703296703297, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI108796653, Length=262, Percent_Identity=30.1526717557252, Blast_Score=91, Evalue=7e-19,
Organism=Homo sapiens, GI14149777, Length=251, Percent_Identity=25.0996015936255, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1786890, Length=250, Percent_Identity=86, Blast_Score=459, Evalue=1e-131,
Organism=Caenorhabditis elegans, GI17562458, Length=284, Percent_Identity=27.112676056338, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17560956, Length=284, Percent_Identity=27.112676056338, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17558880, Length=281, Percent_Identity=27.4021352313167, Blast_Score=87, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI71984613, Length=212, Percent_Identity=27.8301886792453, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562356, Length=234, Percent_Identity=25.2136752136752, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319965, Length=239, Percent_Identity=27.1966527196653, Blast_Score=80, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24666141, Length=253, Percent_Identity=28.4584980237154, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24656326, Length=257, Percent_Identity=28.0155642023346, Blast_Score=104, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24666137, Length=291, Percent_Identity=28.5223367697594, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI22026920, Length=243, Percent_Identity=29.2181069958848, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24656330, Length=275, Percent_Identity=26.9090909090909, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI19920940, Length=249, Percent_Identity=22.8915662650602, Blast_Score=74, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006357
- InterPro:   IPR023215 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 27091; Mature: 26960

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIKSVICDIDGVLLHDNTAIKGANDFLARIQDAGMPLVILTNYPSQTAQDLTNRFITAG
CCHHHEEECCCCEEEECCCCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHEECC
LDVPESAFYTSAMATADFLRRQDGKKAYVIGEGALVHELYKAGFTITDINPDFVIVGETR
CCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHCCCEEEECCCCEEEEECCC
SYNWDMMHKAAYFVANGARFIATNPDSHGHGFAPACGALCAPIEKISGRKPFYVGKPSPW
CCCHHHHHHHEEEEECCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCE
IIRAALNKMQAHSESTVIVGDNLRTDILAGFQAGLETILVLSGVSTLTDIDAMPFRPSYV
EHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCC
YPSVADIDII
CCCCCEEECC
>Mature Secondary Structure 
TIKSVICDIDGVLLHDNTAIKGANDFLARIQDAGMPLVILTNYPSQTAQDLTNRFITAG
CHHHEEECCCCEEEECCCCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHEECC
LDVPESAFYTSAMATADFLRRQDGKKAYVIGEGALVHELYKAGFTITDINPDFVIVGETR
CCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHCCCEEEECCCCEEEEECCC
SYNWDMMHKAAYFVANGARFIATNPDSHGHGFAPACGALCAPIEKISGRKPFYVGKPSPW
CCCHHHHHHHEEEEECCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCE
IIRAALNKMQAHSESTVIVGDNLRTDILAGFQAGLETILVLSGVSTLTDIDAMPFRPSYV
EHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCC
YPSVADIDII
CCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]