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The map label for this gene is cdsA [H]

Identifier: 218928218

GI number: 218928218

Start: 1191103

End: 1191951

Strand: Direct

Name: cdsA [H]

Synonym: YPO1050

Alternate gene names: 218928218

Gene position: 1191103-1191951 (Clockwise)

Preceding gene: 218928217

Following gene: 218928219

Centisome position: 25.59

GC content: 47.94

Gene sequence:

>849_bases
TTGCTGAAGTATCGTCTCATAACTGCTTTGATTTTGATTCCGGTTGTCATTGGTGCACTGTTCCTGCTTCCGCCGGTTGG
TTTCGCTATTGTTACTCTCGTCGTCTGCATGCTTGCAGCCTGGGAATGGGGTCAATTAGCGGGTTTTGCCAGTCGTACTC
AGCGTATCTGGTTAGCGATACTGTGCGGATTCCTGCTTGTTGCCATGCTGCTTAGTCTCCCTGAATATCAGCATTCACCT
CATCACCTCTTGGTGAGTACACCACTATGGCTCTCTATGGGCTGGTGGGTTGCTGCATTGATGCTGGTGCTTACTTACCC
GCGCTCTGCTGTATCTTGGCGTAACTCGCGCCTCCTGCGCATCATCTTCGGTATTCTGACTATTATCCCATTTTTTTGGG
GAATGTTTGCTTTACGCCAGTATGGCTACGAGCAGAACCATAATACCGGCGCTTGGTGGCTGTTATATGTCATGTTATTA
GTGTGGGGGGCAGATTCTGGCGCCTACATGTTTGGTAAATTGTTCGGTAAACACAAATTAGCGCCTAAAGTCTCACCAGG
TAAAACATGGGAAGGATTAATTGGCGGTTTACTGACGTCAGCTCTGATATCATTGCTGTTTGGTCGATACGCACCGTTGG
ATATCGTCCCCGAAAAACTGTTAATCTGTTCCGTGGTTGCTGCATTGGCCTCGGTACTCGGTGATCTGACTGAAAGTATG
TTTAAACGTGAAGCGGGAATCAAAGACAGTGGTCATTTGATTCCTGGTCATGGTGGGATACTGGATCGTATCGATAGCCT
GACCGCAGCTGTGCCGGTATTTGCCTGCTTAATGCTGTTAGTGTTTTAA

Upstream 100 bases:

>100_bases
TGAAAATGTCTTTGAAGGTGCGCTGAATGCATTTGCACAACGCGAGCGTCGCTTCGGGGGAACTACACCTATCGATGCCA
CTGCATCCTAGGGGGAACTT

Downstream 100 bases:

>100_bases
TCCGTCACTGACGGGGAGTTTAGGGATTATGATGAGCATACTCTGGAGCCTGGCTGCGTTTATTGTCGCACTGGGGATCT
TAATTACAGTGCATGAGTTT

Product: CDP-diglyceride synthase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MLKYRLITALILIPVVIGALFLLPPVGFAIVTLVVCMLAAWEWGQLAGFASRTQRIWLAILCGFLLVAMLLSLPEYQHSP
HHLLVSTPLWLSMGWWVAALMLVLTYPRSAVSWRNSRLLRIIFGILTIIPFFWGMFALRQYGYEQNHNTGAWWLLYVMLL
VWGADSGAYMFGKLFGKHKLAPKVSPGKTWEGLIGGLLTSALISLLFGRYAPLDIVPEKLLICSVVAALASVLGDLTESM
FKREAGIKDSGHLIPGHGGILDRIDSLTAAVPVFACLMLLVF

Sequences:

>Translated_282_residues
MLKYRLITALILIPVVIGALFLLPPVGFAIVTLVVCMLAAWEWGQLAGFASRTQRIWLAILCGFLLVAMLLSLPEYQHSP
HHLLVSTPLWLSMGWWVAALMLVLTYPRSAVSWRNSRLLRIIFGILTIIPFFWGMFALRQYGYEQNHNTGAWWLLYVMLL
VWGADSGAYMFGKLFGKHKLAPKVSPGKTWEGLIGGLLTSALISLLFGRYAPLDIVPEKLLICSVVAALASVLGDLTESM
FKREAGIKDSGHLIPGHGGILDRIDSLTAAVPVFACLMLLVF
>Mature_282_residues
MLKYRLITALILIPVVIGALFLLPPVGFAIVTLVVCMLAAWEWGQLAGFASRTQRIWLAILCGFLLVAMLLSLPEYQHSP
HHLLVSTPLWLSMGWWVAALMLVLTYPRSAVSWRNSRLLRIIFGILTIIPFFWGMFALRQYGYEQNHNTGAWWLLYVMLL
VWGADSGAYMFGKLFGKHKLAPKVSPGKTWEGLIGGLLTSALISLLFGRYAPLDIVPEKLLICSVVAALASVLGDLTESM
FKREAGIKDSGHLIPGHGGILDRIDSLTAAVPVFACLMLLVF

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=282, Percent_Identity=76.9503546099291, Blast_Score=424, Evalue=1e-120,
Organism=Escherichia coli, GI1787677, Length=158, Percent_Identity=40.5063291139241, Blast_Score=101, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 31208; Mature: 31208

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure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HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]