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The map label for this gene is sucD [H]

Identifier: 218904963

GI number: 218904963

Start: 3686370

End: 3687272

Strand: Reverse

Name: sucD [H]

Synonym: BCAH820_3847

Alternate gene names: 218904963

Gene position: 3687272-3686370 (Counterclockwise)

Preceding gene: 218904964

Following gene: 218904962

Centisome position: 69.54

GC content: 40.31

Gene sequence:

>903_bases
ATGAGCGTATTAGTTAATAAAGATACAAAAGTTATTGTTCAAGGTATTACAGGTTCTCAAGGATTATTCCACACAAAACA
AATGATTGAATACGGTACGAAAATTGTCGGTGGTGTAACGCCAGGTAAAGGTGGCACTGACATTGAAGGTGTACCAGTAT
TTGATACTGTAGAAGATGCAGTGAAAGCAACAGGCGCAAACGCTTCAGTTGTATACGTTCCACCCGCTTTTGCGGCTGAT
GCAATTATGGAAGCAGTTGATGCAGAAATTGATTTAGTAGTATGTATTACCGAAGGAATTCCTGTATTAGATATGGTAAA
CGTAAAGAGATATATGGCTGGTAAACATACACGTTTACTTGGACCAAACTGCCCAGGTGTTATTACGCCTGATGAATGTA
AAATCGGTATTATGCCAGGATACATTCATAAAAAAGGTCATGTAGGTATCGTATCTCGCTCTGGTACATTAACGTATGAG
GCTGTACATCAGTTAACACAAGAAGGTATTGGCCAATCTACTGCTGTAGGTATCGGCGGAGACCCAGTTAACGGTACAGA
CTTTATTGATGCATTAAAAGCATTTAATGAAGATGAAGAAACACATGCTGTAATTATGATTGGTGAAATCGGTGGTACAG
CGGAAGAAGAGGCAGCTGAATGGGTGAAAGCTAATATGACAAAACCTGTTGTAGGCTTCATTGGTGGCCAAACAGCGCCT
GCTGGCAAACGTATGGGCCATGCTGGTGCAATCATTTCTGGCGGTAAAGGAACTGCTGCAGAAAAGATTAAAACGATGGA
AGCTTGTGGTATTAAAGTAGCGGAAACTCCAGCAGTTATGGGAGAAACGCTAATCTCTGTCTTAAAAGAAAAAGGTCTAT
TTGAGACTTGTAAAAACTACTAA

Upstream 100 bases:

>100_bases
TAAATGAGTCTGGCTTAAATATTGTTGCAGCAGAATCTATGGCAGACGGTGCACAAAAAATTGTTTCACTAGTGGGCTAA
TAGAAAGCGGGGGAGAAAAA

Downstream 100 bases:

>100_bases
TCTGTTGAAAGACACCTTCTTGCTTGAAGGTGTCTTTTTACAAACTTCCTGTTTACATAATAAAAATTATGGGTAAGGAG
AATTGAGATGAAAAGAGAAC

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha; Vegetative protein 239; VEG239 [H]

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MSVLVNKDTKVIVQGITGSQGLFHTKQMIEYGTKIVGGVTPGKGGTDIEGVPVFDTVEDAVKATGANASVVYVPPAFAAD
AIMEAVDAEIDLVVCITEGIPVLDMVNVKRYMAGKHTRLLGPNCPGVITPDECKIGIMPGYIHKKGHVGIVSRSGTLTYE
AVHQLTQEGIGQSTAVGIGGDPVNGTDFIDALKAFNEDEETHAVIMIGEIGGTAEEEAAEWVKANMTKPVVGFIGGQTAP
AGKRMGHAGAIISGGKGTAAEKIKTMEACGIKVAETPAVMGETLISVLKEKGLFETCKNY

Sequences:

>Translated_300_residues
MSVLVNKDTKVIVQGITGSQGLFHTKQMIEYGTKIVGGVTPGKGGTDIEGVPVFDTVEDAVKATGANASVVYVPPAFAAD
AIMEAVDAEIDLVVCITEGIPVLDMVNVKRYMAGKHTRLLGPNCPGVITPDECKIGIMPGYIHKKGHVGIVSRSGTLTYE
AVHQLTQEGIGQSTAVGIGGDPVNGTDFIDALKAFNEDEETHAVIMIGEIGGTAEEEAAEWVKANMTKPVVGFIGGQTAP
AGKRMGHAGAIISGGKGTAAEKIKTMEACGIKVAETPAVMGETLISVLKEKGLFETCKNY
>Mature_299_residues
SVLVNKDTKVIVQGITGSQGLFHTKQMIEYGTKIVGGVTPGKGGTDIEGVPVFDTVEDAVKATGANASVVYVPPAFAADA
IMEAVDAEIDLVVCITEGIPVLDMVNVKRYMAGKHTRLLGPNCPGVITPDECKIGIMPGYIHKKGHVGIVSRSGTLTYEA
VHQLTQEGIGQSTAVGIGGDPVNGTDFIDALKAFNEDEETHAVIMIGEIGGTAEEEAAEWVKANMTKPVVGFIGGQTAPA
GKRMGHAGAIISGGKGTAAEKIKTMEACGIKVAETPAVMGETLISVLKEKGLFETCKNY

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=297, Percent_Identity=61.952861952862, Blast_Score=311, Evalue=4e-85,
Organism=Homo sapiens, GI38569423, Length=254, Percent_Identity=28.3464566929134, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI38569421, Length=254, Percent_Identity=28.3464566929134, Blast_Score=87, Evalue=2e-17,
Organism=Escherichia coli, GI1786949, Length=289, Percent_Identity=65.0519031141868, Blast_Score=377, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI17550194, Length=292, Percent_Identity=62.3287671232877, Blast_Score=344, Evalue=3e-95,
Organism=Caenorhabditis elegans, GI17553126, Length=292, Percent_Identity=59.9315068493151, Blast_Score=331, Evalue=3e-91,
Organism=Caenorhabditis elegans, GI17557344, Length=254, Percent_Identity=25.5905511811024, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17551266, Length=313, Percent_Identity=24.9201277955272, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6324716, Length=293, Percent_Identity=51.1945392491468, Blast_Score=279, Evalue=3e-76,
Organism=Drosophila melanogaster, GI21356559, Length=286, Percent_Identity=58.3916083916084, Blast_Score=342, Evalue=1e-94,
Organism=Drosophila melanogaster, GI28574296, Length=291, Percent_Identity=58.7628865979381, Blast_Score=309, Evalue=2e-84,
Organism=Drosophila melanogaster, GI281363477, Length=258, Percent_Identity=27.906976744186, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI281363475, Length=258, Percent_Identity=27.906976744186, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI281363473, Length=258, Percent_Identity=27.906976744186, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 31212; Mature: 31081

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLVNKDTKVIVQGITGSQGLFHTKQMIEYGTKIVGGVTPGKGGTDIEGVPVFDTVEDA
CCEEECCCCEEEEEECCCCCCHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCHHHHHHH
VKATGANASVVYVPPAFAADAIMEAVDAEIDLVVCITEGIPVLDMVNVKRYMAGKHTRLL
HHHCCCCCEEEEECCHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCEEE
GPNCPGVITPDECKIGIMPGYIHKKGHVGIVSRSGTLTYEAVHQLTQEGIGQSTAVGIGG
CCCCCCCCCCCCCEEEECCCCEECCCCEEEEECCCCCHHHHHHHHHHHCCCCCEEEECCC
DPVNGTDFIDALKAFNEDEETHAVIMIGEIGGTAEEEAAEWVKANMTKPVVGFIGGQTAP
CCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCEEEECCCCCCC
AGKRMGHAGAIISGGKGTAAEKIKTMEACGIKVAETPAVMGETLISVLKEKGLFETCKNY
CCHHCCCCCEEEECCCCCHHHHHHHHHHHCEEEECCHHHHHHHHHHHHHHCCHHHHHHCC
>Mature Secondary Structure 
SVLVNKDTKVIVQGITGSQGLFHTKQMIEYGTKIVGGVTPGKGGTDIEGVPVFDTVEDA
CEEECCCCEEEEEECCCCCCHHHHHHHHHHCCCEECCCCCCCCCCCCCCCCCHHHHHHH
VKATGANASVVYVPPAFAADAIMEAVDAEIDLVVCITEGIPVLDMVNVKRYMAGKHTRLL
HHHCCCCCEEEEECCHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCEEE
GPNCPGVITPDECKIGIMPGYIHKKGHVGIVSRSGTLTYEAVHQLTQEGIGQSTAVGIGG
CCCCCCCCCCCCCEEEECCCCEECCCCEEEEECCCCCHHHHHHHHHHHCCCCCEEEECCC
DPVNGTDFIDALKAFNEDEETHAVIMIGEIGGTAEEEAAEWVKANMTKPVVGFIGGQTAP
CCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCEEEECCCCCCC
AGKRMGHAGAIISGGKGTAAEKIKTMEACGIKVAETPAVMGETLISVLKEKGLFETCKNY
CCHHCCCCCEEEECCCCCHHHHHHHHHHHCEEEECCHHHHHHHHHHHHHHCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9298659 [H]