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The map label for this gene is yebU [C]

Identifier: 218884374

GI number: 218884374

Start: 1007710

End: 1008870

Strand: Direct

Name: yebU [C]

Synonym: DKAM_1063

Alternate gene names: 218884374

Gene position: 1007710-1008870 (Clockwise)

Preceding gene: 218884371

Following gene: 218884377

Centisome position: 73.81

GC content: 45.65

Gene sequence:

>1161_bases
GTGTCGTGGAGGGTGAGGAGTTTACTGGTTAAACCCTATGGAAGCATTGTCGACGTCCTTGTAGAGAAGTTGAAGACTCC
TCCTATGAGAATGTACTTAAGGGTTAACACCGTGAAGACCACGCCTCATAGACTAGTGGAACTATTACGGGAGAGAGGGG
TTGAAGCATATATGGACGAATATATTGAAGAAGCTGTTTACACAGTGGTCCAGGGCCCTTTTCCATTGGAATGTAACACA
GATAAATACATCGTGGTCGACGATAAGACAGCTAGTTCACTAATATTAGGCGCCAACCTCTATCGTCCTGGAGTGGTTAA
ATCAAGCGTCTTCAGTGAAGGCGATAAATTACTAGCTGTGACCAGGCAAGGCACGCCTCTAGCATGCCTGGAGGCTGTTA
CGTCATCAAAGAGCCTCCATAAAATGAGGCAGGGGCTTGTAGCACGTAGCACCTCATCTCCTTTTAAAGCACCAAGGATA
AGCGAGCTGGATATCTATAAACAGGGATTATTATATCCCCAGGGCTATCCAAGCATCGTTACCACTAGAGTCCTTGATCC
CAGGCCAGGTGAACTAATAGTGGACATGAACGCATCGCCAGGGGGCAAGACAAGCCATATAGTACAGTTGACTAAAGGAG
GTGCGAGGATCATAGCTATTGATAGAAGCCCCGGTAAGATCGCCGAGTTAAAGAATAATCTTAGCAACCTGGATTTAGAC
TTAAACGTGATCGCTATCCCGCATGACTCCCGATACCTCCACTACGATTTCAGTTTACTGGGTAAGGTCGATAAAGTTCT
GATAGATCCACCATGCAGTAATCTAGGCGTTAGACCGAGGCTACTCGAGAACAGGAGTTACAAGGATGTGGAGAATCTAT
CTAGCTATCAGAGGCAGTTTCTTAAAACAGCCGCGTTAATAGTGAAACCTGGTGGATATATAGTTTATTCAACGTGCACC
CTTACCCTTGAGGAGAACGAGGAAAACATACTCTATGCTGTCGAGGAACTCGGGTTGGAATGCGTGGAGTTACCTGAGAA
CCCGCCTTACACTGATAAGACAACATATAAAGGCATGATCGGATACAGATATACTCCATTAAACATGGATATGCCAGGTC
ACTTTATAGCTGTGCTTAAGAGGCCTTCCTCTTCCTCCTAA

Upstream 100 bases:

>100_bases
AACCATTTTCCCCACCCTCTTGTAGATATATGGTTAATCTCTAATAAGTTTGACTATATATAGATCCACTAATCTAGGAT
ACAGGGATGGGTTGTAATAG

Downstream 100 bases:

>100_bases
CCAGTGGAGTCCCACATATAGGGCAATTTATTTCTCCTGGATGAGCCGGGATGTATCCGCATGTAGGACAGTACTCGCTG
TACTCCCTGCTGGTTTTAAT

Product: RNA (Cytosine-C(5)-)-methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 385

Protein sequence:

>386_residues
MSWRVRSLLVKPYGSIVDVLVEKLKTPPMRMYLRVNTVKTTPHRLVELLRERGVEAYMDEYIEEAVYTVVQGPFPLECNT
DKYIVVDDKTASSLILGANLYRPGVVKSSVFSEGDKLLAVTRQGTPLACLEAVTSSKSLHKMRQGLVARSTSSPFKAPRI
SELDIYKQGLLYPQGYPSIVTTRVLDPRPGELIVDMNASPGGKTSHIVQLTKGGARIIAIDRSPGKIAELKNNLSNLDLD
LNVIAIPHDSRYLHYDFSLLGKVDKVLIDPPCSNLGVRPRLLENRSYKDVENLSSYQRQFLKTAALIVKPGGYIVYSTCT
LTLEENEENILYAVEELGLECVELPENPPYTDKTTYKGMIGYRYTPLNMDMPGHFIAVLKRPSSSS

Sequences:

>Translated_386_residues
MSWRVRSLLVKPYGSIVDVLVEKLKTPPMRMYLRVNTVKTTPHRLVELLRERGVEAYMDEYIEEAVYTVVQGPFPLECNT
DKYIVVDDKTASSLILGANLYRPGVVKSSVFSEGDKLLAVTRQGTPLACLEAVTSSKSLHKMRQGLVARSTSSPFKAPRI
SELDIYKQGLLYPQGYPSIVTTRVLDPRPGELIVDMNASPGGKTSHIVQLTKGGARIIAIDRSPGKIAELKNNLSNLDLD
LNVIAIPHDSRYLHYDFSLLGKVDKVLIDPPCSNLGVRPRLLENRSYKDVENLSSYQRQFLKTAALIVKPGGYIVYSTCT
LTLEENEENILYAVEELGLECVELPENPPYTDKTTYKGMIGYRYTPLNMDMPGHFIAVLKRPSSSS
>Mature_385_residues
SWRVRSLLVKPYGSIVDVLVEKLKTPPMRMYLRVNTVKTTPHRLVELLRERGVEAYMDEYIEEAVYTVVQGPFPLECNTD
KYIVVDDKTASSLILGANLYRPGVVKSSVFSEGDKLLAVTRQGTPLACLEAVTSSKSLHKMRQGLVARSTSSPFKAPRIS
ELDIYKQGLLYPQGYPSIVTTRVLDPRPGELIVDMNASPGGKTSHIVQLTKGGARIIAIDRSPGKIAELKNNLSNLDLDL
NVIAIPHDSRYLHYDFSLLGKVDKVLIDPPCSNLGVRPRLLENRSYKDVENLSSYQRQFLKTAALIVKPGGYIVYSTCTL
TLEENEENILYAVEELGLECVELPENPPYTDKTTYKGMIGYRYTPLNMDMPGHFIAVLKRPSSSS

Specific function: May act as RNA methyltransferase [H]

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI32698918, Length=379, Percent_Identity=28.2321899736148, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI76150625, Length=261, Percent_Identity=31.0344827586207, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI76150623, Length=261, Percent_Identity=31.0344827586207, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI23199998, Length=239, Percent_Identity=29.7071129707113, Blast_Score=85, Evalue=9e-17,
Organism=Homo sapiens, GI270288816, Length=239, Percent_Identity=29.7071129707113, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI8922322, Length=239, Percent_Identity=29.7071129707113, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI270288818, Length=239, Percent_Identity=29.7071129707113, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI40316918, Length=171, Percent_Identity=31.5789473684211, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI87081985, Length=221, Percent_Identity=30.316742081448, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI2367212, Length=149, Percent_Identity=32.8859060402685, Blast_Score=79, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI115534021, Length=252, Percent_Identity=30.952380952381, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71998419, Length=252, Percent_Identity=30.952380952381, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17536757, Length=236, Percent_Identity=27.9661016949153, Blast_Score=86, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6324268, Length=236, Percent_Identity=30.5084745762712, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24668781, Length=351, Percent_Identity=30.7692307692308, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI21356513, Length=351, Percent_Identity=30.7692307692308, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI22024126, Length=226, Percent_Identity=29.646017699115, Blast_Score=89, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR011023 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu [H]

EC number: NA

Molecular weight: Translated: 43085; Mature: 42954

Theoretical pI: Translated: 8.59; Mature: 8.59

Prosite motif: PS50890 PUA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWRVRSLLVKPYGSIVDVLVEKLKTPPMRMYLRVNTVKTTPHRLVELLRERGVEAYMDE
CCCCCHHHHHCCCHHHHHHHHHHHCCCCEEEEEEEEEECCCHHHHHHHHHHCCHHHHHHH
YIEEAVYTVVQGPFPLECNTDKYIVVDDKTASSLILGANLYRPGVVKSSVFSEGDKLLAV
HHHHHHHHHHCCCCCEEECCCCEEEEECCCCCEEEEECCCCCCCCCHHHHHCCCCEEEEE
TRQGTPLACLEAVTSSKSLHKMRQGLVARSTSSPFKAPRISELDIYKQGLLYPQGYPSIV
ECCCCCHHHHHHHHCCHHHHHHHHHHEECCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCE
TTRVLDPRPGELIVDMNASPGGKTSHIVQLTKGGARIIAIDRSPGKIAELKNNLSNLDLD
EEEECCCCCCCEEEECCCCCCCCCEEEEEEECCCEEEEEEECCCCHHHHHHCCCCCCCEE
LNVIAIPHDSRYLHYDFSLLGKVDKVLIDPPCSNLGVRPRLLENRSYKDVENLSSYQRQF
EEEEEECCCCCEEEECHHHHCCCCEEEECCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHH
LKTAALIVKPGGYIVYSTCTLTLEENEENILYAVEELGLECVELPENPPYTDKTTYKGMI
HHHHEEEECCCCEEEEEEEEEEEECCCCCEEEEHHHCCCEEEECCCCCCCCCCCCCCCEE
GYRYTPLNMDMPGHFIAVLKRPSSSS
EEEEECCCCCCCCCEEEEEECCCCCC
>Mature Secondary Structure 
SWRVRSLLVKPYGSIVDVLVEKLKTPPMRMYLRVNTVKTTPHRLVELLRERGVEAYMDE
CCCCHHHHHCCCHHHHHHHHHHHCCCCEEEEEEEEEECCCHHHHHHHHHHCCHHHHHHH
YIEEAVYTVVQGPFPLECNTDKYIVVDDKTASSLILGANLYRPGVVKSSVFSEGDKLLAV
HHHHHHHHHHCCCCCEEECCCCEEEEECCCCCEEEEECCCCCCCCCHHHHHCCCCEEEEE
TRQGTPLACLEAVTSSKSLHKMRQGLVARSTSSPFKAPRISELDIYKQGLLYPQGYPSIV
ECCCCCHHHHHHHHCCHHHHHHHHHHEECCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCE
TTRVLDPRPGELIVDMNASPGGKTSHIVQLTKGGARIIAIDRSPGKIAELKNNLSNLDLD
EEEECCCCCCCEEEECCCCCCCCCEEEEEEECCCEEEEEEECCCCHHHHHHCCCCCCCEE
LNVIAIPHDSRYLHYDFSLLGKVDKVLIDPPCSNLGVRPRLLENRSYKDVENLSSYQRQF
EEEEEECCCCCEEEECHHHHCCCCEEEECCCCCCCCCCCHHHCCCCCCCHHHHHHHHHHH
LKTAALIVKPGGYIVYSTCTLTLEENEENILYAVEELGLECVELPENPPYTDKTTYKGMI
HHHHEEEECCCCEEEEEEEEEEEECCCCCEEEEHHHCCCEEEECCCCCCCCCCCCCCCEE
GYRYTPLNMDMPGHFIAVLKRPSSSS
EEEEECCCCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]