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The map label for this gene is yprA [H]

Identifier: 218884065

GI number: 218884065

Start: 725130

End: 727418

Strand: Reverse

Name: yprA [H]

Synonym: DKAM_0754

Alternate gene names: 218884065

Gene position: 727418-725130 (Counterclockwise)

Preceding gene: 218884068

Following gene: 218884060

Centisome position: 53.28

GC content: 44.34

Gene sequence:

>2289_bases
ATGGGCCTGGTGTTCAGGGATCCTCTGGTTAACGAGGTGGATGAGGAACTTAGATCCAGGTATCCTGAGAGCGGGGTAGC
TGTTATATATGAGAGAGTGGAGGAGACACGTGAACCAGAGCCTGGTCCAAGTATAGAGGAATTAGATCTACCCGGCGAAG
TAGCCAGGATTCTTCACCGTAGAGGAATTAGGAGACTGTATAGATTCCAGTATGAGGCATATCGTCACATTCTAAACAGG
GAAAACACTGTGATATCGGCTGGTACAAGTACCGGGAAAACTGAAGCATTTCTGCTCCCTATCTTGAGGGAGATATATTA
TGTGAGGAAGAGTAATCCAAGAGCTATGATACTATATCCAACGAAGGCCCTTGCAAGGGATCAGCTTAATAGGTTTACTG
ATTACACTGTGTATCCAATAATAGGCTTCAGCATATATGATGGAGATACACCCAGGAGGCAAAGAGAGAAAATAGGATTG
AATCCACCCTCACTCATAATATCGAATCCGGATATGCTACATATAGGGTTAGTGTATAGCTCATATATTAGGGGCTTCGT
GGAGAACAGTGAGTTCATGGTTTTCGATGAATTACATGTCTACGAGGGAGTTCTAGGCAGCCACATACATCATCTTGTTG
AGAGAATAAAGAGAACCAGCAGGGAGAAACCAGTATTCATAGGTTCATCTGCAACAATTGGTAACCCAAAGGAGTTCGCT
GAGGAATTATTTGGTGAGGAAGTCGTTGAGGTGAGGGGTGAGGCGTTCAGAAAGGGCATGGTTACACATGTACTGGTTTC
ATCAGGCTATTTAAGCAGGTGGAGCGTCGTAGCTTATCTATGCTACATCCTGTCTAGGAGGGGTTTAAAATACATTGTTT
TCGTTGATAGCCAGCAACTAGCTGAGTTGCTCACAAGGATTCTTAAGACCAGGTATAACGTAAACATTATGGTTCACCGT
GCCGGCCTACCTGCTGATGTAAGAAGGGATATCGAAGTAAAACTGAGAAATGGCTTAATAGATGGAGTTGTAGCAACTTC
TACGTTAGAGCTTGGCATAGATATAGGAGCATTGGATGCTACTGTAATGGCTATGCCTCCCCCCTCATACTCGAAGTACC
TACAGAGAGCTGGTAGAGCTGGTAGACGAAGGAAAGGCTATGTTTTCACAGTGCTAGGGGACGACCCGATAGATGTATAC
TATGCTAGATCCCCGGAACGGTTTTTCACGCAGTCAATTCCACCGTCCGTTATAGAGCCCTCGAATGAGGAAGTAGCTAA
GACGCATCTAGTAGCATATCTTCTCCAATCATGGAGAGCCAGGATCGATAGCATACCTGGTGAATGGAGAAATATTATAG
ATGAGTTAGTGGCTGAGGGGATCGTGAAGAAGACTGGAGAGTATATAAGACCTATACCTGTCTCTGCTAGGAGGCTCCTA
AGTACACAGGGTGGTTTAAGAGGGATGGGCCCTATTGTGGAGATAGTTGATTCTAGTAGTGGAGATACGTTGGCCACGAG
GGAGTTACCTGTGGCACTCCTGGAATTATATCCCGGCGCCATCTACCTGTACATGGGGGAACCATATATTGTTGAGTCGT
TGAACCTAGTGGAAAAGAAAGCACTTGTTAAGACACCGGGGGAAAATATAACGGTATATACCAGGCCATTATATACTGTT
GACGTCGTTAACTACGATGTATTAATGGAGAGAAAGAGTAGCAGAGGAATAATGGCGTCTTATGCCAAAGTAGTATTAGA
GCTAAGCGTGAACGGGGTAGTCGTCAAAGACATGTATACTGGTGAAACAAGATTCACAATGGATCTTGAAAAACCCATTA
AATATCAGTATTCAACCAGGGCGCTTCTATTAAAATACCCTGCATATGAGGAGCTAGGGATAAAGGGTTGTGCAGAAGCA
TTTCACGCAATAGAGCATGCATTAATTTCAGCGGCGAGAGTGACATGCGGCTCTGGTTTAACAGATTTAGGCGGTATAAG
CTATCCTAGTGGCGATATAGTAATATATGACTCAGCTATAGGTGGCAGCGGCTTATCTAAGCTACTCTATAAGAGACTGG
AAGAAACAGAGGATGTAGCATTAGAAATCATGGGCAAGTGCGACTGCTATGATGGATGCCCAAGATGTATCTATAGTCCA
TACTGTGGTAATAACAACCAGATACTCTCACGGAGGAAAGCAATATACGTACTCAGTAAAATTAGAGAAGGCAAGGCTCA
AGCAGTAGCACACCCCCTTGAGTTGCGTGGGGGAAAGCCATTGGTTTAA

Upstream 100 bases:

>100_bases
TTGGGAGGCTAATTAAAAATAATTGTCTCTGTTAACAAATATATATTTCGTTCCCGGGAACTGGAGGCTGCAACTAGAGA
TTCATCGACCTGTAACGGGG

Downstream 100 bases:

>100_bases
GTAATTTAGCTCCCTAAAGCATTGATATAGGTAGTGATGAGGGTCCCGAATAAAGAGCCGTGTGGCTGTGAAGAGACTAC
AGGTGCTGAGTACTTTTTCA

Product: DEAD/DEAH box helicase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 762; Mature: 761

Protein sequence:

>762_residues
MGLVFRDPLVNEVDEELRSRYPESGVAVIYERVEETREPEPGPSIEELDLPGEVARILHRRGIRRLYRFQYEAYRHILNR
ENTVISAGTSTGKTEAFLLPILREIYYVRKSNPRAMILYPTKALARDQLNRFTDYTVYPIIGFSIYDGDTPRRQREKIGL
NPPSLIISNPDMLHIGLVYSSYIRGFVENSEFMVFDELHVYEGVLGSHIHHLVERIKRTSREKPVFIGSSATIGNPKEFA
EELFGEEVVEVRGEAFRKGMVTHVLVSSGYLSRWSVVAYLCYILSRRGLKYIVFVDSQQLAELLTRILKTRYNVNIMVHR
AGLPADVRRDIEVKLRNGLIDGVVATSTLELGIDIGALDATVMAMPPPSYSKYLQRAGRAGRRRKGYVFTVLGDDPIDVY
YARSPERFFTQSIPPSVIEPSNEEVAKTHLVAYLLQSWRARIDSIPGEWRNIIDELVAEGIVKKTGEYIRPIPVSARRLL
STQGGLRGMGPIVEIVDSSSGDTLATRELPVALLELYPGAIYLYMGEPYIVESLNLVEKKALVKTPGENITVYTRPLYTV
DVVNYDVLMERKSSRGIMASYAKVVLELSVNGVVVKDMYTGETRFTMDLEKPIKYQYSTRALLLKYPAYEELGIKGCAEA
FHAIEHALISAARVTCGSGLTDLGGISYPSGDIVIYDSAIGGSGLSKLLYKRLEETEDVALEIMGKCDCYDGCPRCIYSP
YCGNNNQILSRRKAIYVLSKIREGKAQAVAHPLELRGGKPLV

Sequences:

>Translated_762_residues
MGLVFRDPLVNEVDEELRSRYPESGVAVIYERVEETREPEPGPSIEELDLPGEVARILHRRGIRRLYRFQYEAYRHILNR
ENTVISAGTSTGKTEAFLLPILREIYYVRKSNPRAMILYPTKALARDQLNRFTDYTVYPIIGFSIYDGDTPRRQREKIGL
NPPSLIISNPDMLHIGLVYSSYIRGFVENSEFMVFDELHVYEGVLGSHIHHLVERIKRTSREKPVFIGSSATIGNPKEFA
EELFGEEVVEVRGEAFRKGMVTHVLVSSGYLSRWSVVAYLCYILSRRGLKYIVFVDSQQLAELLTRILKTRYNVNIMVHR
AGLPADVRRDIEVKLRNGLIDGVVATSTLELGIDIGALDATVMAMPPPSYSKYLQRAGRAGRRRKGYVFTVLGDDPIDVY
YARSPERFFTQSIPPSVIEPSNEEVAKTHLVAYLLQSWRARIDSIPGEWRNIIDELVAEGIVKKTGEYIRPIPVSARRLL
STQGGLRGMGPIVEIVDSSSGDTLATRELPVALLELYPGAIYLYMGEPYIVESLNLVEKKALVKTPGENITVYTRPLYTV
DVVNYDVLMERKSSRGIMASYAKVVLELSVNGVVVKDMYTGETRFTMDLEKPIKYQYSTRALLLKYPAYEELGIKGCAEA
FHAIEHALISAARVTCGSGLTDLGGISYPSGDIVIYDSAIGGSGLSKLLYKRLEETEDVALEIMGKCDCYDGCPRCIYSP
YCGNNNQILSRRKAIYVLSKIREGKAQAVAHPLELRGGKPLV
>Mature_761_residues
GLVFRDPLVNEVDEELRSRYPESGVAVIYERVEETREPEPGPSIEELDLPGEVARILHRRGIRRLYRFQYEAYRHILNRE
NTVISAGTSTGKTEAFLLPILREIYYVRKSNPRAMILYPTKALARDQLNRFTDYTVYPIIGFSIYDGDTPRRQREKIGLN
PPSLIISNPDMLHIGLVYSSYIRGFVENSEFMVFDELHVYEGVLGSHIHHLVERIKRTSREKPVFIGSSATIGNPKEFAE
ELFGEEVVEVRGEAFRKGMVTHVLVSSGYLSRWSVVAYLCYILSRRGLKYIVFVDSQQLAELLTRILKTRYNVNIMVHRA
GLPADVRRDIEVKLRNGLIDGVVATSTLELGIDIGALDATVMAMPPPSYSKYLQRAGRAGRRRKGYVFTVLGDDPIDVYY
ARSPERFFTQSIPPSVIEPSNEEVAKTHLVAYLLQSWRARIDSIPGEWRNIIDELVAEGIVKKTGEYIRPIPVSARRLLS
TQGGLRGMGPIVEIVDSSSGDTLATRELPVALLELYPGAIYLYMGEPYIVESLNLVEKKALVKTPGENITVYTRPLYTVD
VVNYDVLMERKSSRGIMASYAKVVLELSVNGVVVKDMYTGETRFTMDLEKPIKYQYSTRALLLKYPAYEELGIKGCAEAF
HAIEHALISAARVTCGSGLTDLGGISYPSGDIVIYDSAIGGSGLSKLLYKRLEETEDVALEIMGKCDCYDGCPRCIYSPY
CGNNNQILSRRKAIYVLSKIREGKAQAVAHPLELRGGKPLV

Specific function: Unknown

COG id: COG1205

COG function: function code R; Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI50659095, Length=358, Percent_Identity=23.463687150838, Blast_Score=89, Evalue=2e-17,
Organism=Escherichia coli, GI1787942, Length=570, Percent_Identity=25.0877192982456, Blast_Score=93, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI71999646, Length=379, Percent_Identity=22.9551451187335, Blast_Score=73, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71999644, Length=379, Percent_Identity=22.9551451187335, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17508543, Length=380, Percent_Identity=25, Blast_Score=69, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320497, Length=738, Percent_Identity=25.0677506775068, Blast_Score=189, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR018973
- InterPro:   IPR011545
- InterPro:   IPR001650
- InterPro:   IPR014021 [H]

Pfam domain/function: PF00270 DEAD; PF09369 DUF1998; PF00271 Helicase_C [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 85632; Mature: 85501

Theoretical pI: Translated: 7.98; Mature: 7.98

Prosite motif: PS00018 EF_HAND_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLVFRDPLVNEVDEELRSRYPESGVAVIYERVEETREPEPGPSIEELDLPGEVARILHR
CCCEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHH
RGIRRLYRFQYEAYRHILNRENTVISAGTSTGKTEAFLLPILREIYYVRKSNPRAMILYP
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEC
TKALARDQLNRFTDYTVYPIIGFSIYDGDTPRRQREKIGLNPPSLIISNPDMLHIGLVYS
CHHHHHHHHHHHCCEEEEEEEEEEEECCCCCHHHHHHCCCCCCCEEECCCCEEEEHHHHH
SYIRGFVENSEFMVFDELHVYEGVLGSHIHHLVERIKRTSREKPVFIGSSATIGNPKEFA
HHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHH
EELFGEEVVEVRGEAFRKGMVTHVLVSSGYLSRWSVVAYLCYILSRRGLKYIVFVDSQQL
HHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEECCHHH
AELLTRILKTRYNVNIMVHRAGLPADVRRDIEVKLRNGLIDGVVATSTLELGIDIGALDA
HHHHHHHHHCCCCEEEEEEECCCCHHHHCCHHHHHHCCCHHHHHHHEEEEECCEEECCCE
TVMAMPPPSYSKYLQRAGRAGRRRKGYVFTVLGDDPIDVYYARSPERFFTQSIPPSVIEP
EEEECCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEECCCCHHHHHCCCCCCCCCC
SNEEVAKTHLVAYLLQSWRARIDSIPGEWRNIIDELVAEGIVKKTGEYIRPIPVSARRLL
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
STQGGLRGMGPIVEIVDSSSGDTLATRELPVALLELYPGAIYLYMGEPYIVESLNLVEKK
HHCCCCCCCCHHHHEEECCCCCEEEEHHHHHHHHHHCCCEEEEEECCCCEEHHHHHHHHH
ALVKTPGENITVYTRPLYTVDVVNYDVLMERKSSRGIMASYAKVVLELSVNGVVVKDMYT
HHHCCCCCCEEEEECCEEEEEEECHHHHHHCCCCCCHHHHHHHHHHEEECCCEEEEEEEC
GETRFTMDLEKPIKYQYSTRALLLKYPAYEELGIKGCAEAFHAIEHALISAARVTCGSGL
CCEEEEEECCCCCCEEECCCEEEEECCCHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCC
TDLGGISYPSGDIVIYDSAIGGSGLSKLLYKRLEETEDVALEIMGKCDCYDGCPRCIYSP
CCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCC
YCGNNNQILSRRKAIYVLSKIREGKAQAVAHPLELRGGKPLV
CCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCHHHCCCCCCCC
>Mature Secondary Structure 
GLVFRDPLVNEVDEELRSRYPESGVAVIYERVEETREPEPGPSIEELDLPGEVARILHR
CCEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHH
RGIRRLYRFQYEAYRHILNRENTVISAGTSTGKTEAFLLPILREIYYVRKSNPRAMILYP
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEC
TKALARDQLNRFTDYTVYPIIGFSIYDGDTPRRQREKIGLNPPSLIISNPDMLHIGLVYS
CHHHHHHHHHHHCCEEEEEEEEEEEECCCCCHHHHHHCCCCCCCEEECCCCEEEEHHHHH
SYIRGFVENSEFMVFDELHVYEGVLGSHIHHLVERIKRTSREKPVFIGSSATIGNPKEFA
HHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHH
EELFGEEVVEVRGEAFRKGMVTHVLVSSGYLSRWSVVAYLCYILSRRGLKYIVFVDSQQL
HHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEEECCHHH
AELLTRILKTRYNVNIMVHRAGLPADVRRDIEVKLRNGLIDGVVATSTLELGIDIGALDA
HHHHHHHHHCCCCEEEEEEECCCCHHHHCCHHHHHHCCCHHHHHHHEEEEECCEEECCCE
TVMAMPPPSYSKYLQRAGRAGRRRKGYVFTVLGDDPIDVYYARSPERFFTQSIPPSVIEP
EEEECCCCCHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEECCCCHHHHHCCCCCCCCCC
SNEEVAKTHLVAYLLQSWRARIDSIPGEWRNIIDELVAEGIVKKTGEYIRPIPVSARRLL
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
STQGGLRGMGPIVEIVDSSSGDTLATRELPVALLELYPGAIYLYMGEPYIVESLNLVEKK
HHCCCCCCCCHHHHEEECCCCCEEEEHHHHHHHHHHCCCEEEEEECCCCEEHHHHHHHHH
ALVKTPGENITVYTRPLYTVDVVNYDVLMERKSSRGIMASYAKVVLELSVNGVVVKDMYT
HHHCCCCCCEEEEECCEEEEEEECHHHHHHCCCCCCHHHHHHHHHHEEECCCEEEEEEEC
GETRFTMDLEKPIKYQYSTRALLLKYPAYEELGIKGCAEAFHAIEHALISAARVTCGSGL
CCEEEEEECCCCCCEEECCCEEEEECCCHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCC
TDLGGISYPSGDIVIYDSAIGGSGLSKLLYKRLEETEDVALEIMGKCDCYDGCPRCIYSP
CCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCC
YCGNNNQILSRRKAIYVLSKIREGKAQAVAHPLELRGGKPLV
CCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on acid anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]