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The map label for this gene is 218883639

Identifier: 218883639

GI number: 218883639

Start: 302485

End: 303345

Strand: Reverse

Name: 218883639

Synonym: DKAM_0328

Alternate gene names: NA

Gene position: 303345-302485 (Counterclockwise)

Preceding gene: 218883640

Following gene: 218883633

Centisome position: 22.22

GC content: 45.3

Gene sequence:

>861_bases
ATGACAAGAGGTAGCTTACTAAAGGAATTAGCGAGAGAGATACTTGGAGAGGGGGTTGCCGAGAAGGTCTGGAGAAGGGT
TGAGTTCATAGGCGATCTCGCATTAATCAGGACACCGTTGGATATGAGCCCTGAGGAGTTAAAGCCGTTAGCCCTTGAGA
TTCTGAAGCGCTTTAACTTCGTTAAAAGCGTATGGGCAGCTATCCCAGGAGTAGAGGGGCCTTATAGGCTGAGGAAACAT
GTGTTGCTGGCGGGAGAGGACAGGAGTGAAACACTGTATAGGGAACATGGCTGCATCTTCAAGGTGGATATAAATAAGGT
ATATATATCTCCCAGCTTAAACTACGAGCACTATAGGATCGCTAAACTAGTGGCTCCTGGTGAGACGGTTTTGAACATGT
TTGCTGGTGCCGGGTTGTTCAGTATAATAATAGCTAGATACGCCAAGCCGAGGAAAGTATACAGTATAGATATAAATCCA
TACGCATACCACTACATGGTTGAAAACGTGAGGTTGAACCATGTGGAGGACGTGGTCGAACCCATCCTAGGCGATGCTGG
TGAGGTAGTGAATTCAAGGCTCACTAATACAAGCGACAGGGTGTTAATGCCGTATCCTGAACTGGCCCTCGACTATCTCG
ACAAGACATTGATGGCGTTGAGGGATGGAAGAGGATGGATACACGTGTATCTACATGTTAAAACGGCGAAGGGTGAGCAT
TATTTAACCAAGGCTGAACAACTAGTGGCTGAAAAACTTGCCTCACTCGGTGTGAGAAATTATGATATTTCAAGTAAGAG
GAAGATAAGGAATGTAGGGCCACGTACTCATCAAGTAGTAGTGGATATTAAAATATTGTAG

Upstream 100 bases:

>100_bases
TATCTTATAACACATGGTAGGAGAACATGCAGGGCGCGGAAACCCCTTTGCAATAAATGCGTCTTGAGAGACATGTGCAA
GTATGGGGTTGACACTCTCG

Downstream 100 bases:

>100_bases
AGATTATAGAGATATCATAACCAGGTGTGTTTCATGAGGGTGCTTAGAGTATTTTACGTGGCACTAGTAGTGGTTCTCCT
ATGTTTACAATACGCAACCC

Product: methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 285

Protein sequence:

>286_residues
MTRGSLLKELAREILGEGVAEKVWRRVEFIGDLALIRTPLDMSPEELKPLALEILKRFNFVKSVWAAIPGVEGPYRLRKH
VLLAGEDRSETLYREHGCIFKVDINKVYISPSLNYEHYRIAKLVAPGETVLNMFAGAGLFSIIIARYAKPRKVYSIDINP
YAYHYMVENVRLNHVEDVVEPILGDAGEVVNSRLTNTSDRVLMPYPELALDYLDKTLMALRDGRGWIHVYLHVKTAKGEH
YLTKAEQLVAEKLASLGVRNYDISSKRKIRNVGPRTHQVVVDIKIL

Sequences:

>Translated_286_residues
MTRGSLLKELAREILGEGVAEKVWRRVEFIGDLALIRTPLDMSPEELKPLALEILKRFNFVKSVWAAIPGVEGPYRLRKH
VLLAGEDRSETLYREHGCIFKVDINKVYISPSLNYEHYRIAKLVAPGETVLNMFAGAGLFSIIIARYAKPRKVYSIDINP
YAYHYMVENVRLNHVEDVVEPILGDAGEVVNSRLTNTSDRVLMPYPELALDYLDKTLMALRDGRGWIHVYLHVKTAKGEH
YLTKAEQLVAEKLASLGVRNYDISSKRKIRNVGPRTHQVVVDIKIL
>Mature_285_residues
TRGSLLKELAREILGEGVAEKVWRRVEFIGDLALIRTPLDMSPEELKPLALEILKRFNFVKSVWAAIPGVEGPYRLRKHV
LLAGEDRSETLYREHGCIFKVDINKVYISPSLNYEHYRIAKLVAPGETVLNMFAGAGLFSIIIARYAKPRKVYSIDINPY
AYHYMVENVRLNHVEDVVEPILGDAGEVVNSRLTNTSDRVLMPYPELALDYLDKTLMALRDGRGWIHVYLHVKTAKGEHY
LTKAEQLVAEKLASLGVRNYDISSKRKIRNVGPRTHQVVVDIKIL

Specific function: Unknown

COG id: COG2520

COG function: function code R; Predicted methyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase trmD family [H]

Homologues:

Organism=Homo sapiens, GI145275187, Length=245, Percent_Identity=27.3469387755102, Blast_Score=89, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6321861, Length=185, Percent_Identity=28.1081081081081, Blast_Score=73, Evalue=5e-14,
Organism=Drosophila melanogaster, GI45551508, Length=248, Percent_Identity=26.2096774193548, Blast_Score=71, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003402 [H]

Pfam domain/function: PF02475 Met_10 [H]

EC number: NA

Molecular weight: Translated: 32563; Mature: 32432

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRGSLLKELAREILGEGVAEKVWRRVEFIGDLALIRTPLDMSPEELKPLALEILKRFNF
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
VKSVWAAIPGVEGPYRLRKHVLLAGEDRSETLYREHGCIFKVDINKVYISPSLNYEHYRI
HHHHHHHCCCCCCHHHHHHEEEEECCCCHHHHHHHCCCEEEEECCEEEECCCCCCCCEEE
AKLVAPGETVLNMFAGAGLFSIIIARYAKPRKVYSIDINPYAYHYMVENVRLNHVEDVVE
EEEECCCHHHHHHHHCCHHHHHHHHHHCCCCEEEEEECCCEEEEEEEECCCHHHHHHHHH
PILGDAGEVVNSRLTNTSDRVLMPYPELALDYLDKTLMALRDGRGWIHVYLHVKTAKGEH
HHHCCHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCH
YLTKAEQLVAEKLASLGVRNYDISSKRKIRNVGPRTHQVVVDIKIL
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCEEEEEEEEEC
>Mature Secondary Structure 
TRGSLLKELAREILGEGVAEKVWRRVEFIGDLALIRTPLDMSPEELKPLALEILKRFNF
CHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
VKSVWAAIPGVEGPYRLRKHVLLAGEDRSETLYREHGCIFKVDINKVYISPSLNYEHYRI
HHHHHHHCCCCCCHHHHHHEEEEECCCCHHHHHHHCCCEEEEECCEEEECCCCCCCCEEE
AKLVAPGETVLNMFAGAGLFSIIIARYAKPRKVYSIDINPYAYHYMVENVRLNHVEDVVE
EEEECCCHHHHHHHHCCHHHHHHHHHHCCCCEEEEEECCCEEEEEEEECCCHHHHHHHHH
PILGDAGEVVNSRLTNTSDRVLMPYPELALDYLDKTLMALRDGRGWIHVYLHVKTAKGEH
HHHCCHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCCCH
YLTKAEQLVAEKLASLGVRNYDISSKRKIRNVGPRTHQVVVDIKIL
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]