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The map label for this gene is frr [H]

Identifier: 218710315

GI number: 218710315

Start: 2519222

End: 2519809

Strand: Reverse

Name: frr [H]

Synonym: VS_2350

Alternate gene names: 218710315

Gene position: 2519809-2519222 (Counterclockwise)

Preceding gene: 218710316

Following gene: 218710314

Centisome position: 76.37

GC content: 42.52

Gene sequence:

>588_bases
TTGAAGAAAGAACATAATCAAGGTGAAATTGTGATTAACGAAATCAAAAAAGACGCTCAAGAGCGCATGGTAAAAAGTGT
TGATGCACTAAAAAACAGCCTACAAAAAATCCGTACAGGCCGTGCTCACCCGAGCCTACTTTCTGGTCTTACTGTTGAGT
ACTACGGTGCACCAACACCTTTGACTCAAGTAGCTAACGTTATTGCTGAAGACGCACGTACACTAGCAATTACAGTGTTT
GATAAAACACTGACTCCTCTTGTTGAAAAAGCAATCATGACTTCTGACCTAGGCTTAAACCCTATGTCTGCAGGTACGGT
TATTCGCGTTCCACTTCCACCGCTTACGGAAGAGCGTCGTAAAGACCTAGTTAAAATCGTTCGTGGCGAAGCTGAAGGTG
GCCGTGTTGCTATTCGTAACATCCGTCGTGACGCGAATGGCGATCTAAAAGCGCTTCTTAAAGACAAAGAAATTTCAGAA
GACGAAGATCGTAAAGCACAAGACGAAATTCAAAAGCTAACTGACGCTGCGGTTAAGAACGTAGACGAAGTTCTAGCAGT
TAAAGAAAAAGAGTTGATGGAAGTTTAA

Upstream 100 bases:

>100_bases
CTGAAGGTACATTAATCAGCGACGCTGACTAATTTTTCGGGCTTACTGAAGTATAATGCTTCGGTAAGCTTATCCTTATC
ACTCCAAATAAAAAGCTTTC

Downstream 100 bases:

>100_bases
TTTTCCATATTCTTTTCTTTCAGGAAAAACGCTGTACTCACGGTGCAGCGTTTTTTTATGCTATTCTGTTCGACTATTAG
AATTTGATTCACTCTTTTAT

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MKKEHNQGEIVINEIKKDAQERMVKSVDALKNSLQKIRTGRAHPSLLSGLTVEYYGAPTPLTQVANVIAEDARTLAITVF
DKTLTPLVEKAIMTSDLGLNPMSAGTVIRVPLPPLTEERRKDLVKIVRGEAEGGRVAIRNIRRDANGDLKALLKDKEISE
DEDRKAQDEIQKLTDAAVKNVDEVLAVKEKELMEV

Sequences:

>Translated_195_residues
MKKEHNQGEIVINEIKKDAQERMVKSVDALKNSLQKIRTGRAHPSLLSGLTVEYYGAPTPLTQVANVIAEDARTLAITVF
DKTLTPLVEKAIMTSDLGLNPMSAGTVIRVPLPPLTEERRKDLVKIVRGEAEGGRVAIRNIRRDANGDLKALLKDKEISE
DEDRKAQDEIQKLTDAAVKNVDEVLAVKEKELMEV
>Mature_195_residues
MKKEHNQGEIVINEIKKDAQERMVKSVDALKNSLQKIRTGRAHPSLLSGLTVEYYGAPTPLTQVANVIAEDARTLAITVF
DKTLTPLVEKAIMTSDLGLNPMSAGTVIRVPLPPLTEERRKDLVKIVRGEAEGGRVAIRNIRRDANGDLKALLKDKEISE
DEDRKAQDEIQKLTDAAVKNVDEVLAVKEKELMEV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=179, Percent_Identity=30.1675977653631, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI291042689, Length=105, Percent_Identity=39.0476190476191, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1786368, Length=185, Percent_Identity=68.1081081081081, Blast_Score=262, Evalue=1e-71,
Organism=Drosophila melanogaster, GI24661488, Length=174, Percent_Identity=29.3103448275862, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 21602; Mature: 21602

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKEHNQGEIVINEIKKDAQERMVKSVDALKNSLQKIRTGRAHPSLLSGLTVEYYGAPTP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCEEECCCCCC
LTQVANVIAEDARTLAITVFDKTLTPLVEKAIMTSDLGLNPMSAGTVIRVPLPPLTEERR
HHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHH
KDLVKIVRGEAEGGRVAIRNIRRDANGDLKALLKDKEISEDEDRKAQDEIQKLTDAAVKN
HHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
VDEVLAVKEKELMEV
HHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKEHNQGEIVINEIKKDAQERMVKSVDALKNSLQKIRTGRAHPSLLSGLTVEYYGAPTP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCEEECCCCCC
LTQVANVIAEDARTLAITVFDKTLTPLVEKAIMTSDLGLNPMSAGTVIRVPLPPLTEERR
HHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHH
KDLVKIVRGEAEGGRVAIRNIRRDANGDLKALLKDKEISEDEDRKAQDEIQKLTDAAVKN
HHHHHHHHCCCCCCHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
VDEVLAVKEKELMEV
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA