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The map label for this gene is yrhP [H]

Identifier: 218709283

GI number: 218709283

Start: 1387381

End: 1388016

Strand: Direct

Name: yrhP [H]

Synonym: VS_1290

Alternate gene names: 218709283

Gene position: 1387381-1388016 (Clockwise)

Preceding gene: 218709281

Following gene: 218709285

Centisome position: 42.05

GC content: 46.23

Gene sequence:

>636_bases
ATGGATATTTTGAACTTTGAGGCATTTTTAATTGCCATTACTATTTTAACGCTCACGCCGGGTTTAGATACGGCTTTGGT
GATTCGCAATACGAGCCGTTCTGGCTTATCTGACGGCGTGATGACCAGCTTTGGTATTTGTAGCGGCTTGTATGTACACG
CGTTTTTCTCTGCTGTGGGTATTTCTGCAATCCTCGCCCAGTCAGCTGAACTCTTTCAAGCCGTTAAGATGGTGGGTGCG
GTTTACCTGATCTGGCTCGGCTTAAGCAGTTTACGAGCTTTGATGAAAAACGGTGGCGGTTTGAAGGTAGGCGAACAAGC
ACAGCAGGCTTACAGTGCTAAGCGTTCTTTGCGTGAAGGCTTTCTGTCTAACGTTCTTAACCCAAAAACGGCAGTTTTCT
ATTTGGCCTTTTTACCTCAATTCGTAAACCCTGAAGGATCACCATTATTGCAATCTATGTTGATGGCTTCGGTGCACTTT
ATGATTGCGATGGTGTGGCAATGCGGTTTGGCAGGGGCACTTAACTCGGCTAAAAACTTGCTTAAGAATGCGAGTTTTAT
GAAGTGGATGGAAGGCGTGACTGGCATGGTGCTGGTGGGGCTGGGTGTGAAGCTTTTAATGGAAGAACCTAGCTAA

Upstream 100 bases:

>100_bases
CACAAAATCAGTGAGTTGTATAGCTGGTGGCAATTGTTGCTTGCGAATTGTTCAGATACACGGTATTGATGATAGATCGC
TGAACAACAATGACAATGAT

Downstream 100 bases:

>100_bases
GTCATAGTGACTTAATACCAATCACAGTAAGTAAGTGATCAAAAATAGCGCAGGGAAAAGGCTTGAGAACAAGGCAGGAT
TTTTCGATAAGTAGTTATTC

Product: hypothetical protein

Products: homoserine lactone [Periplasm]; Proton [Cytoplasm]; homoserine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MDILNFEAFLIAITILTLTPGLDTALVIRNTSRSGLSDGVMTSFGICSGLYVHAFFSAVGISAILAQSAELFQAVKMVGA
VYLIWLGLSSLRALMKNGGGLKVGEQAQQAYSAKRSLREGFLSNVLNPKTAVFYLAFLPQFVNPEGSPLLQSMLMASVHF
MIAMVWQCGLAGALNSAKNLLKNASFMKWMEGVTGMVLVGLGVKLLMEEPS

Sequences:

>Translated_211_residues
MDILNFEAFLIAITILTLTPGLDTALVIRNTSRSGLSDGVMTSFGICSGLYVHAFFSAVGISAILAQSAELFQAVKMVGA
VYLIWLGLSSLRALMKNGGGLKVGEQAQQAYSAKRSLREGFLSNVLNPKTAVFYLAFLPQFVNPEGSPLLQSMLMASVHF
MIAMVWQCGLAGALNSAKNLLKNASFMKWMEGVTGMVLVGLGVKLLMEEPS
>Mature_211_residues
MDILNFEAFLIAITILTLTPGLDTALVIRNTSRSGLSDGVMTSFGICSGLYVHAFFSAVGISAILAQSAELFQAVKMVGA
VYLIWLGLSSLRALMKNGGGLKVGEQAQQAYSAKRSLREGFLSNVLNPKTAVFYLAFLPQFVNPEGSPLLQSMLMASVHF
MIAMVWQCGLAGALNSAKNLLKNASFMKWMEGVTGMVLVGLGVKLLMEEPS

Specific function: Conducts The Efflux Of Homoserine And Homoserine Lactone. [C]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994979, Length=188, Percent_Identity=26.5957446808511, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788099, Length=141, Percent_Identity=29.0780141843972, Blast_Score=73, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 22604; Mature: 22604

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDILNFEAFLIAITILTLTPGLDTALVIRNTSRSGLSDGVMTSFGICSGLYVHAFFSAVG
CCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ISAILAQSAELFQAVKMVGAVYLIWLGLSSLRALMKNGGGLKVGEQAQQAYSAKRSLREG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
FLSNVLNPKTAVFYLAFLPQFVNPEGSPLLQSMLMASVHFMIAMVWQCGLAGALNSAKNL
HHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKNASFMKWMEGVTGMVLVGLGVKLLMEEPS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDILNFEAFLIAITILTLTPGLDTALVIRNTSRSGLSDGVMTSFGICSGLYVHAFFSAVG
CCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
ISAILAQSAELFQAVKMVGAVYLIWLGLSSLRALMKNGGGLKVGEQAQQAYSAKRSLREG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
FLSNVLNPKTAVFYLAFLPQFVNPEGSPLLQSMLMASVHFMIAMVWQCGLAGALNSAKNL
HHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKNASFMKWMEGVTGMVLVGLGVKLLMEEPS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; homoserine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + homoserine lactone [Cytoplasm] = Proton [Cytoplasm] + homoserine lactone [Periplasm] Proton [Periplasm] + homoserine [Cytoplasm] = Proton [Cytoplasm] + homoserine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377; 9308178 [H]