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The map label for this gene is ruvC [H]

Identifier: 218709099

GI number: 218709099

Start: 1169435

End: 1169956

Strand: Direct

Name: ruvC [H]

Synonym: VS_1105

Alternate gene names: 218709099

Gene position: 1169435-1169956 (Clockwise)

Preceding gene: 218709098

Following gene: 218709100

Centisome position: 35.44

GC content: 48.47

Gene sequence:

>522_bases
ATGTCTATTATCTTAGGGATTGACCCTGGCTCTCGCATTACCGGCTATGGCGTGATTCGTCAAAATGGTCGCCATCTATA
TTACTTAGGTAGTGGTTGTATTCGTACTTCCGAAAAAGAACTGCCAGGTCGACTAAAACAGATTTACGCTGGCGTGAGCG
AAATCATCACTCAGTTTCAGCCAGATGTGTTTGCGATCGAGCAGGTTTTCATGTCGAAGAACGCTGATTCTGCACTTAAG
CTTGGACAAGCTCGTGGTAGTGCGATTGTGGCAGCGGTGAATGCGGATTTACCCGTTCATGAATATGCGGCTCGTTTGAT
CAAACAAGCGGTGACAGGTAATGGTGGTGCTGATAAGTCGATGGTTCAGAACATGGTGATGAGCATGCTCAAGCTACCTG
CCAAACCACAGGCTGATGCTGCCGATGCTCTCGGCGTAGCGATCACTCACGCTAACACCAATAAAACCTTGGTTGCACTG
GCAGGTAAAGCAACGGGAGCGAGAAAAGGACGCTACCGTTAA

Upstream 100 bases:

>100_bases
TGTGAGTAAATTAGAAAATGCCCGTTAATTTGACGGGCATTTTTTTTTGCGTTCGATATACTAAGCTGAAAAGCATGTAT
AAATAATCAGTATTGAAGTT

Downstream 100 bases:

>100_bases
TCCCCCTATCGCTTTCTAGAAGTTTTCTTTCGATGAGCCTTACGCCCCGTTTGGCTCATATCAAAACAATACGCACCTAA
ATCCTTGATGAAATGAGATC

Product: Holliday junction resolvase

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC [H]

Number of amino acids: Translated: 173; Mature: 172

Protein sequence:

>173_residues
MSIILGIDPGSRITGYGVIRQNGRHLYYLGSGCIRTSEKELPGRLKQIYAGVSEIITQFQPDVFAIEQVFMSKNADSALK
LGQARGSAIVAAVNADLPVHEYAARLIKQAVTGNGGADKSMVQNMVMSMLKLPAKPQADAADALGVAITHANTNKTLVAL
AGKATGARKGRYR

Sequences:

>Translated_173_residues
MSIILGIDPGSRITGYGVIRQNGRHLYYLGSGCIRTSEKELPGRLKQIYAGVSEIITQFQPDVFAIEQVFMSKNADSALK
LGQARGSAIVAAVNADLPVHEYAARLIKQAVTGNGGADKSMVQNMVMSMLKLPAKPQADAADALGVAITHANTNKTLVAL
AGKATGARKGRYR
>Mature_172_residues
SIILGIDPGSRITGYGVIRQNGRHLYYLGSGCIRTSEKELPGRLKQIYAGVSEIITQFQPDVFAIEQVFMSKNADSALKL
GQARGSAIVAAVNADLPVHEYAARLIKQAVTGNGGADKSMVQNMVMSMLKLPAKPQADAADALGVAITHANTNKTLVALA
GKATGARKGRYR

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family [H]

Homologues:

Organism=Escherichia coli, GI1788170, Length=173, Percent_Identity=69.364161849711, Blast_Score=224, Evalue=2e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012337
- InterPro:   IPR020563
- InterPro:   IPR002176 [H]

Pfam domain/function: PF02075 RuvC [H]

EC number: =3.1.22.4 [H]

Molecular weight: Translated: 18356; Mature: 18224

Theoretical pI: Translated: 10.38; Mature: 10.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIILGIDPGSRITGYGVIRQNGRHLYYLGSGCIRTSEKELPGRLKQIYAGVSEIITQFQ
CEEEEECCCCCCEEEEEEEEECCCEEEEECCCCEECCCHHHHHHHHHHHHHHHHHHHHHC
PDVFAIEQVFMSKNADSALKLGQARGSAIVAAVNADLPVHEYAARLIKQAVTGNGGADKS
CCHHHHHHHHHCCCCCHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCHH
MVQNMVMSMLKLPAKPQADAADALGVAITHANTNKTLVALAGKATGARKGRYR
HHHHHHHHHHHCCCCCCCCCCCHHEEEEEECCCCCEEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
SIILGIDPGSRITGYGVIRQNGRHLYYLGSGCIRTSEKELPGRLKQIYAGVSEIITQFQ
EEEEECCCCCCEEEEEEEEECCCEEEEECCCCEECCCHHHHHHHHHHHHHHHHHHHHHC
PDVFAIEQVFMSKNADSALKLGQARGSAIVAAVNADLPVHEYAARLIKQAVTGNGGADKS
CCHHHHHHHHHCCCCCHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCHH
MVQNMVMSMLKLPAKPQADAADALGVAITHANTNKTLVALAGKATGARKGRYR
HHHHHHHHHHHCCCCCCCCCCCHHEEEEEECCCCCEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA