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The map label for this gene is ptsG [H]

Identifier: 218709026

GI number: 218709026

Start: 1072554

End: 1073984

Strand: Direct

Name: ptsG [H]

Synonym: VS_1032

Alternate gene names: 218709026

Gene position: 1072554-1073984 (Clockwise)

Preceding gene: 218709025

Following gene: 218709027

Centisome position: 32.51

GC content: 47.1

Gene sequence:

>1431_bases
ATGTTTAAGAACCTTTTTGCTAGCCTGCAGAAAGTTGGTAAGTCTCTGATGCTACCAGTATCAGTTTTACCAGTTGCGGG
TATTTTGCTAGGTGTCGGTGCAGCAGACCTTCCTTTCATTCCAGAAATCGTTTCAAACTTAATGGAACAAGCGGGTGGTT
CAGTATTCGGTCAAATGGCACTACTGTTCGCAGTGGGCGTAGCACTTGGCTTTACTAATAACGACGGTGTAGCTGGTCTA
GCTGCTATCGTTGGTTACGGCATCATGACTGCTACACTAGGCGTAATGGCTGGTGTAATGGGCGTTGATAAAATCGACAC
TGGTGTACTAGGTGGTATTCTAGTCGGTGGTGTTGCTGCTTGGGCATTCAACCGTTTCTTCCGTATTCAACTACCAGAGT
ACCTTGGCTTCTTCGCTGGTAAGCGTGCTGTGCCAATCATCACAGGTTTCTCTGCGATTGGTCTAGCAATCCTACTATCT
GTAGTATGGCCACCAGTTGGCGGCGCTATCTCTGCGTTCTCTGATTGGGCTGCTCACCAAAACCCACAAGTGGCGTTTGG
TATCTACGGTATCGTTGAGCGTTCTCTGATTCCATTTGGTCTTCACCACGTTTGGAACGTACCTTTCTTCTTCGAAGCTG
GTACTTGTGTAAACGCTGCTGGCGAAACTCAAAACGGTGTTCTTACTTGTTACCTAGTTGCTGATGACGCATCTCGTGCA
GCGGGCAATGGCTTCGGTCAGCTAGCTGGTGGTTACATGTTCAAGATGTTCGGTCTACCTGCTGCTGCAATCGCGATTGC
ACATTCAGCTAAACCTGAAAACCGCGCTAAAGTAATGGGCATCATGGCTTCTGCTGCGTTGACTTCATTCCTAACGGGTA
TCACTGAACCAATCGAATTCTCATTCCTATTCGTTGCTCCTGTACTGTACGCAATCCACGCTCTATTAGCTGGTTCTGCA
TACGTTCTTGCGAACACTCTAGGTTTTGTACACGGTACATCTTTCTCACACGGTCTAATCGACTTCCTAGTTCTATCTGG
CAACGCGTCTAAGATGGGTCTAATGGTTGTATGTGGTGTTGCTTACGCTGCAATTTACTACATCGTATTCCGCACTGTGA
TTAAAGCACTTGACCTTAAAACTCCGGGCCGTGAAGACGAATCTGAAGAAGAAGTAGTTGCTACAGGTTCTGAACTTGCT
GGTGAGCTAGTTGCTGCATTCGGTGGTAAAGCGAACATCACTGGTCTTGACGCTTGTATTACTCGTCTACGTGTTGCAGT
AGCTGATACCGCTCTTGTTGACCAAGACAAACTGAAGAAACTAGGCGCTGCAGGTGTTGTTGTAGTTGCTGGTGGCGTAC
AAGCTATCTTCGGTACTAAGTCTGACAACCTTAAGACAGACATGGATGAGTGGATCCGTAACAACGGTTAA

Upstream 100 bases:

>100_bases
GCAATACATGGTTACATTTTCACTGGGTGCTAACATATAGGCTACGGGGGTGTGCCGTTAGGACCCATATAATTATTTTA
TCTTTATCAGGAGCATAAAC

Downstream 100 bases:

>100_bases
TTCGCTGATTCAATAAATTGAAAGGAGGCCTTACGGCCTCTTTTTTTGTTTTCTACAATATGCAAAATATCCTCACGCTT
AAGCTCTTCTTACTCAACTA

Product: PTS system glucose-specific transporter subunits IIBC

Products: NA

Alternate protein names: EIICB-Glc; EII-Glc; Glucose permease IIC component; PTS system glucose-specific EIIC component; Glucose-specific phosphotransferase enzyme IIB component; PTS system glucose-specific EIIB component [H]

Number of amino acids: Translated: 476; Mature: 476

Protein sequence:

>476_residues
MFKNLFASLQKVGKSLMLPVSVLPVAGILLGVGAADLPFIPEIVSNLMEQAGGSVFGQMALLFAVGVALGFTNNDGVAGL
AAIVGYGIMTATLGVMAGVMGVDKIDTGVLGGILVGGVAAWAFNRFFRIQLPEYLGFFAGKRAVPIITGFSAIGLAILLS
VVWPPVGGAISAFSDWAAHQNPQVAFGIYGIVERSLIPFGLHHVWNVPFFFEAGTCVNAAGETQNGVLTCYLVADDASRA
AGNGFGQLAGGYMFKMFGLPAAAIAIAHSAKPENRAKVMGIMASAALTSFLTGITEPIEFSFLFVAPVLYAIHALLAGSA
YVLANTLGFVHGTSFSHGLIDFLVLSGNASKMGLMVVCGVAYAAIYYIVFRTVIKALDLKTPGREDESEEEVVATGSELA
GELVAAFGGKANITGLDACITRLRVAVADTALVDQDKLKKLGAAGVVVVAGGVQAIFGTKSDNLKTDMDEWIRNNG

Sequences:

>Translated_476_residues
MFKNLFASLQKVGKSLMLPVSVLPVAGILLGVGAADLPFIPEIVSNLMEQAGGSVFGQMALLFAVGVALGFTNNDGVAGL
AAIVGYGIMTATLGVMAGVMGVDKIDTGVLGGILVGGVAAWAFNRFFRIQLPEYLGFFAGKRAVPIITGFSAIGLAILLS
VVWPPVGGAISAFSDWAAHQNPQVAFGIYGIVERSLIPFGLHHVWNVPFFFEAGTCVNAAGETQNGVLTCYLVADDASRA
AGNGFGQLAGGYMFKMFGLPAAAIAIAHSAKPENRAKVMGIMASAALTSFLTGITEPIEFSFLFVAPVLYAIHALLAGSA
YVLANTLGFVHGTSFSHGLIDFLVLSGNASKMGLMVVCGVAYAAIYYIVFRTVIKALDLKTPGREDESEEEVVATGSELA
GELVAAFGGKANITGLDACITRLRVAVADTALVDQDKLKKLGAAGVVVVAGGVQAIFGTKSDNLKTDMDEWIRNNG
>Mature_476_residues
MFKNLFASLQKVGKSLMLPVSVLPVAGILLGVGAADLPFIPEIVSNLMEQAGGSVFGQMALLFAVGVALGFTNNDGVAGL
AAIVGYGIMTATLGVMAGVMGVDKIDTGVLGGILVGGVAAWAFNRFFRIQLPEYLGFFAGKRAVPIITGFSAIGLAILLS
VVWPPVGGAISAFSDWAAHQNPQVAFGIYGIVERSLIPFGLHHVWNVPFFFEAGTCVNAAGETQNGVLTCYLVADDASRA
AGNGFGQLAGGYMFKMFGLPAAAIAIAHSAKPENRAKVMGIMASAALTSFLTGITEPIEFSFLFVAPVLYAIHALLAGSA
YVLANTLGFVHGTSFSHGLIDFLVLSGNASKMGLMVVCGVAYAAIYYIVFRTVIKALDLKTPGREDESEEEVVATGSELA
GELVAAFGGKANITGLDACITRLRVAVADTALVDQDKLKKLGAAGVVVVAGGVQAIFGTKSDNLKTDMDEWIRNNG

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787343, Length=484, Percent_Identity=65.2892561983471, Blast_Score=629, Evalue=0.0,
Organism=Escherichia coli, GI1786894, Length=480, Percent_Identity=39.7916666666667, Blast_Score=287, Evalue=1e-78,
Organism=Escherichia coli, GI1787908, Length=518, Percent_Identity=33.3976833976834, Blast_Score=251, Evalue=9e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011299 [H]

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 49384; Mature: 49384

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKNLFASLQKVGKSLMLPVSVLPVAGILLGVGAADLPFIPEIVSNLMEQAGGSVFGQMA
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHH
LLFAVGVALGFTNNDGVAGLAAIVGYGIMTATLGVMAGVMGVDKIDTGVLGGILVGGVAA
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
WAFNRFFRIQLPEYLGFFAGKRAVPIITGFSAIGLAILLSVVWPPVGGAISAFSDWAAHQ
HHHHHHEEEECHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCC
NPQVAFGIYGIVERSLIPFGLHHVWNVPFFFEAGTCVNAAGETQNGVLTCYLVADDASRA
CCCEEEHHHHHHHHHHCHHHHHHHHCCCEEEECCCEECCCCCCCCCEEEEEEEECCCCHH
AGNGFGQLAGGYMFKMFGLPAAAIAIAHSAKPENRAKVMGIMASAALTSFLTGITEPIEF
CCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHH
SFLFVAPVLYAIHALLAGSAYVLANTLGFVHGTSFSHGLIDFLVLSGNASKMGLMVVCGV
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHEEEEECCCCCHHHHHHHHHH
AYAAIYYIVFRTVIKALDLKTPGREDESEEEVVATGSELAGELVAAFGGKANITGLDACI
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCHHHHHHHHHHCCCCCCCCHHHHHH
TRLRVAVADTALVDQDKLKKLGAAGVVVVAGGVQAIFGTKSDNLKTDMDEWIRNNG
HHHHHHHHHHHHCCHHHHHHCCCCCEEEEECCHHEEECCCCCCCCCCHHHHHHCCC
>Mature Secondary Structure
MFKNLFASLQKVGKSLMLPVSVLPVAGILLGVGAADLPFIPEIVSNLMEQAGGSVFGQMA
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHH
LLFAVGVALGFTNNDGVAGLAAIVGYGIMTATLGVMAGVMGVDKIDTGVLGGILVGGVAA
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
WAFNRFFRIQLPEYLGFFAGKRAVPIITGFSAIGLAILLSVVWPPVGGAISAFSDWAAHQ
HHHHHHEEEECHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCC
NPQVAFGIYGIVERSLIPFGLHHVWNVPFFFEAGTCVNAAGETQNGVLTCYLVADDASRA
CCCEEEHHHHHHHHHHCHHHHHHHHCCCEEEECCCEECCCCCCCCCEEEEEEEECCCCHH
AGNGFGQLAGGYMFKMFGLPAAAIAIAHSAKPENRAKVMGIMASAALTSFLTGITEPIEF
CCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHH
SFLFVAPVLYAIHALLAGSAYVLANTLGFVHGTSFSHGLIDFLVLSGNASKMGLMVVCGV
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHEEEEECCCCCHHHHHHHHHH
AYAAIYYIVFRTVIKALDLKTPGREDESEEEVVATGSELAGELVAAFGGKANITGLDACI
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCHHHHHHHHHHCCCCCCCCHHHHHH
TRLRVAVADTALVDQDKLKKLGAAGVVVVAGGVQAIFGTKSDNLKTDMDEWIRNNG
HHHHHHHHHHHHCCHHHHHHCCCCCEEEEECCHHEEECCCCCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]