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The map label for this gene is ycfH [C]

Identifier: 218709025

GI number: 218709025

Start: 1071342

End: 1072109

Strand: Direct

Name: ycfH [C]

Synonym: VS_1031

Alternate gene names: 218709025

Gene position: 1071342-1072109 (Clockwise)

Preceding gene: 218709024

Following gene: 218709026

Centisome position: 32.47

GC content: 44.27

Gene sequence:

>768_bases
ATGTTCGTAGATTCCCATTGTCATTTAGACAAACTGGATTACCAAAATTTACACACCAGCGTAGAAGACGTGGTTAATAA
AGCGAAAGCAGCCAACGTTGACCAACTGCTTTCTGTCGGTGTGACGTTGGATTCGTTTGAAAACATGCTTGAGATGATCT
CGCCGTTTGATAACGTTAAGGCTTCGTGTGGCGTTCACCCTCTCGACGTAGAGAGCGACTTCTGTTTAGAAAGAATGCGT
GAGTACGCGAGCAACCCGAAAGTGGTGGCTATTGGTGAAACTGGCCTAGATTATCATTACCAACCAGAGACTGCAGAGCT
ACAACAGCTCAGGTTCAAGCAGCACGTTGAGTTGGCTGTTGAGCTTAATAAACCTTTGATCATCCACACGCGTAACGCGC
GTGAAGATACGTTAGCTATTTTACGCGATGGCGGAGCAGAGAAGTGTGGTGGTGTGATTCACTGCTTTACTGAAGATCAA
GCGTTCGCTGAAGCGGCAATGGAATTAGGTTTCTATATCTCGATCTCAGGTATTGTGACCTTTAAACAAGCCACAGAACT
TAAAGACGTTGTGAAAAAACTACCTCTAGATAGGTTGCTGATCGAAACGGATTCGCCATATTTGGCGCCAATTCCATATC
GTGGTAAAGAGAATCAGCCTGCATATGTAGTCGAAGTTGCGGCTTATATCGCCCAGTTAAAAGGGGTATCAATGAAAGAG
GTTGCTGAACAAACGACCAAAAATTACCAAAAACTTTTTTTGCGATAG

Upstream 100 bases:

>100_bases
CGAATAAACTGCTGATATTGATTGAGCAGTTAAAGCAACACCCTGGGCTCAATACGGAGCTACTCATAATGAATTGGCTG
ATAGCCACTTGCGAGGAAAC

Downstream 100 bases:

>100_bases
AAATCTAACTAAACAAACAAAAGGGAGCGAAAGCTCCCTTTTTGTGTTTTTGATCACCAAAAATGCGTTTTTTTTTAATG
TTTACGGAATATGTTGAACT

Product: putative Mg-dependent DNase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MFVDSHCHLDKLDYQNLHTSVEDVVNKAKAANVDQLLSVGVTLDSFENMLEMISPFDNVKASCGVHPLDVESDFCLERMR
EYASNPKVVAIGETGLDYHYQPETAELQQLRFKQHVELAVELNKPLIIHTRNAREDTLAILRDGGAEKCGGVIHCFTEDQ
AFAEAAMELGFYISISGIVTFKQATELKDVVKKLPLDRLLIETDSPYLAPIPYRGKENQPAYVVEVAAYIAQLKGVSMKE
VAEQTTKNYQKLFLR

Sequences:

>Translated_255_residues
MFVDSHCHLDKLDYQNLHTSVEDVVNKAKAANVDQLLSVGVTLDSFENMLEMISPFDNVKASCGVHPLDVESDFCLERMR
EYASNPKVVAIGETGLDYHYQPETAELQQLRFKQHVELAVELNKPLIIHTRNAREDTLAILRDGGAEKCGGVIHCFTEDQ
AFAEAAMELGFYISISGIVTFKQATELKDVVKKLPLDRLLIETDSPYLAPIPYRGKENQPAYVVEVAAYIAQLKGVSMKE
VAEQTTKNYQKLFLR
>Mature_255_residues
MFVDSHCHLDKLDYQNLHTSVEDVVNKAKAANVDQLLSVGVTLDSFENMLEMISPFDNVKASCGVHPLDVESDFCLERMR
EYASNPKVVAIGETGLDYHYQPETAELQQLRFKQHVELAVELNKPLIIHTRNAREDTLAILRDGGAEKCGGVIHCFTEDQ
AFAEAAMELGFYISISGIVTFKQATELKDVVKKLPLDRLLIETDSPYLAPIPYRGKENQPAYVVEVAAYIAQLKGVSMKE
VAEQTTKNYQKLFLR

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349730, Length=269, Percent_Identity=33.457249070632, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI226061853, Length=274, Percent_Identity=33.9416058394161, Blast_Score=115, Evalue=3e-26,
Organism=Homo sapiens, GI110349734, Length=269, Percent_Identity=33.8289962825279, Blast_Score=115, Evalue=4e-26,
Organism=Homo sapiens, GI226061614, Length=256, Percent_Identity=32.421875, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI225903424, Length=223, Percent_Identity=30.0448430493274, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI226061595, Length=231, Percent_Identity=32.034632034632, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI14042943, Length=273, Percent_Identity=24.5421245421245, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI225903439, Length=227, Percent_Identity=25.9911894273128, Blast_Score=79, Evalue=4e-15,
Organism=Escherichia coli, GI1787342, Length=253, Percent_Identity=55.3359683794466, Blast_Score=296, Evalue=7e-82,
Organism=Escherichia coli, GI48994985, Length=239, Percent_Identity=33.0543933054393, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI87082439, Length=256, Percent_Identity=30.078125, Blast_Score=124, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI17559024, Length=281, Percent_Identity=29.5373665480427, Blast_Score=125, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI71980746, Length=263, Percent_Identity=25.4752851711027, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17543026, Length=189, Percent_Identity=31.7460317460317, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17565396, Length=299, Percent_Identity=25.0836120401338, Blast_Score=87, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24586117, Length=203, Percent_Identity=33.0049261083744, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI221330018, Length=203, Percent_Identity=33.0049261083744, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24648690, Length=266, Percent_Identity=30.8270676691729, Blast_Score=94, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 28638; Mature: 28638

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS01137 TATD_1 ; PS01090 TATD_2 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFVDSHCHLDKLDYQNLHTSVEDVVNKAKAANVDQLLSVGVTLDSFENMLEMISPFDNVK
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHCCHHCCH
ASCGVHPLDVESDFCLERMREYASNPKVVAIGETGLDYHYQPETAELQQLRFKQHVELAV
HHCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHEEEE
ELNKPLIIHTRNAREDTLAILRDGGAEKCGGVIHCFTEDQAFAEAAMELGFYISISGIVT
EECCCEEEEECCCCHHHHHHHHCCCCHHCCCEEEEEECCHHHHHHHHHHCEEEEEECEEE
FKQATELKDVVKKLPLDRLLIETDSPYLAPIPYRGKENQPAYVVEVAAYIAQLKGVSMKE
EHHHHHHHHHHHHCCHHHEEEECCCCEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCHHH
VAEQTTKNYQKLFLR
HHHHHHHHHHHHHCC
>Mature Secondary Structure
MFVDSHCHLDKLDYQNLHTSVEDVVNKAKAANVDQLLSVGVTLDSFENMLEMISPFDNVK
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHCCHHCCH
ASCGVHPLDVESDFCLERMREYASNPKVVAIGETGLDYHYQPETAELQQLRFKQHVELAV
HHCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHEEEE
ELNKPLIIHTRNAREDTLAILRDGGAEKCGGVIHCFTEDQAFAEAAMELGFYISISGIVT
EECCCEEEEECCCCHHHHHHHHCCCCHHCCCEEEEEECCHHHHHHHHHHCEEEEEECEEE
FKQATELKDVVKKLPLDRLLIETDSPYLAPIPYRGKENQPAYVVEVAAYIAQLKGVSMKE
EHHHHHHHHHHHHCCHHHEEEECCCCEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCHHH
VAEQTTKNYQKLFLR
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]