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The map label for this gene is ntrC [H]

Identifier: 218708819

GI number: 218708819

Start: 839797

End: 841260

Strand: Direct

Name: ntrC [H]

Synonym: VS_0819

Alternate gene names: 218708819

Gene position: 839797-841260 (Clockwise)

Preceding gene: 218708818

Following gene: 218708820

Centisome position: 25.45

GC content: 43.92

Gene sequence:

>1464_bases
ATGCAAGGTTTGGCAAAACTGCTTGTCGTCGATGATAACGCTCAAAATCGTCACAATTTAAGCACAATATTAGAGTTTGT
AGGAGAGAGCTGCGAAGTAATCAGCTCTGAACAAGCACACAAAGTTGACTGGTCCCTACAGTGGGCCGGTTGCATCATTG
GTTCAATTAAAGCCAAAGGCTTCGCATTACTGAATGAAAAGCTTGTTCATGTTAATCACATCCCTTTACTGGTGATTGGC
AAAAACGATTACCCGGTTGAGGAACTTACTAACTTTGTTGGTGAACTCGAACTTCCTCTTAACTATCCGCAATTAAGTGA
TGCACTGAGACACTGTAAAGACTTCTTAGGCCGTAAAGGCGTTCAAATTTTACCTTCAGCGCGTAAGAACACGCTTTTTC
GTAGTCTAGTTGGGCAGAGTGTTGGTATCCAAGAAGTTCGTCACTTGATTGAACAAGTCTCTTCTACTGAAGCAAACGTA
TTGATTCTTGGCGAGTCAGGCACGGGCAAAGAAGTTGTAGCACGTAATGTTCACTATCATTCTAAACGTCGTTCAGGACC
TTTCGTTCCCGTAAACTGTGGCGCTATACCGCCAGACTTGCTCGAAAGTGAACTGTTTGGTCATGAGAAGGGCGCGTTTA
CTGGTGCAATTACCGCACGTAAAGGCCGTTTTGAGTTGGCTGAAGGTGGTACACTGTTTCTGGATGAAATTGGTGATATG
CCAATGGCGATGCAAGTTAAGTTGCTTCGTGTTTTACAAGAACGCAGTTTTGAACGTGTAGGTGGCAATAGTACCATTCA
AGCTGATGTTCGAGTGATTGCGGCAACACACCGCAATCTTGAAAACATGATCGAAGATGATTTGTTCCGTGAAGATCTTT
ACTATCGCTTGAACGTTTTCCCAATTGAAATGCCATCGCTTCAGGAGCGAAAAGAAGATGTTCCCCTATTGCTTCAGGAG
TTGATGACCAGAATGGAAGCTGAAGGTGGCATGCCAATCTGTTTTACTCCCCGTGCAATCAACTCTTTGATGGAGCATTG
CTGGCCGGGCAACGTACGTGAGTTAGCTAATTTAGTTGAGCGAATGGTTATTTTATATCCAAATAGCTTGGTTGATGTGA
ATCATCTACCAACTAAATATAGATACAGTGATATCCCAGAGTTTCAGCCAGAGTTTAATAATTTTGCATCAGAGGAAGAG
CAAGAGCGAGATGCTCTTTCTGACTTGTTCTCGGAAGACTTCAGTTTTGAGCAGCACGATGAGCTTGCTGACAATGCGAA
CGCACCTCAAGATTTACCCGCTGAAGGGGTTAACTTGAAAGAACTACTCGCTGATATGGAAGTGAATATGATCAATCAAG
CGTTGGAGGCTCAGGGCGGTATTGTTGCTCGCGCTGCTGACATGCTTGGAATGCGCAGAACCACTCTGGTCGAAAAAATG
CGTAAATATAACTTGCAGCGTTAG

Upstream 100 bases:

>100_bases
GTCCACGTAGATCATAATCATTGATATTTTCTCTGTTTTGTCTCTTACGTCGCTTACCAATTTCCGCATCGCACCAAAAT
AAAGGCAATAATTCCTACTT

Downstream 100 bases:

>100_bases
TGCCTATTTTCGATGAAAACGAAAACTAGTACACACTTTAGCATTTTAGCTTTTTGGCAACTTTAGCTAAACGAACAGAT
AAACCATAGTCGAGTTGTTG

Product: polar flagellar protein FlaK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 487; Mature: 487

Protein sequence:

>487_residues
MQGLAKLLVVDDNAQNRHNLSTILEFVGESCEVISSEQAHKVDWSLQWAGCIIGSIKAKGFALLNEKLVHVNHIPLLVIG
KNDYPVEELTNFVGELELPLNYPQLSDALRHCKDFLGRKGVQILPSARKNTLFRSLVGQSVGIQEVRHLIEQVSSTEANV
LILGESGTGKEVVARNVHYHSKRRSGPFVPVNCGAIPPDLLESELFGHEKGAFTGAITARKGRFELAEGGTLFLDEIGDM
PMAMQVKLLRVLQERSFERVGGNSTIQADVRVIAATHRNLENMIEDDLFREDLYYRLNVFPIEMPSLQERKEDVPLLLQE
LMTRMEAEGGMPICFTPRAINSLMEHCWPGNVRELANLVERMVILYPNSLVDVNHLPTKYRYSDIPEFQPEFNNFASEEE
QERDALSDLFSEDFSFEQHDELADNANAPQDLPAEGVNLKELLADMEVNMINQALEAQGGIVARAADMLGMRRTTLVEKM
RKYNLQR

Sequences:

>Translated_487_residues
MQGLAKLLVVDDNAQNRHNLSTILEFVGESCEVISSEQAHKVDWSLQWAGCIIGSIKAKGFALLNEKLVHVNHIPLLVIG
KNDYPVEELTNFVGELELPLNYPQLSDALRHCKDFLGRKGVQILPSARKNTLFRSLVGQSVGIQEVRHLIEQVSSTEANV
LILGESGTGKEVVARNVHYHSKRRSGPFVPVNCGAIPPDLLESELFGHEKGAFTGAITARKGRFELAEGGTLFLDEIGDM
PMAMQVKLLRVLQERSFERVGGNSTIQADVRVIAATHRNLENMIEDDLFREDLYYRLNVFPIEMPSLQERKEDVPLLLQE
LMTRMEAEGGMPICFTPRAINSLMEHCWPGNVRELANLVERMVILYPNSLVDVNHLPTKYRYSDIPEFQPEFNNFASEEE
QERDALSDLFSEDFSFEQHDELADNANAPQDLPAEGVNLKELLADMEVNMINQALEAQGGIVARAADMLGMRRTTLVEKM
RKYNLQR
>Mature_487_residues
MQGLAKLLVVDDNAQNRHNLSTILEFVGESCEVISSEQAHKVDWSLQWAGCIIGSIKAKGFALLNEKLVHVNHIPLLVIG
KNDYPVEELTNFVGELELPLNYPQLSDALRHCKDFLGRKGVQILPSARKNTLFRSLVGQSVGIQEVRHLIEQVSSTEANV
LILGESGTGKEVVARNVHYHSKRRSGPFVPVNCGAIPPDLLESELFGHEKGAFTGAITARKGRFELAEGGTLFLDEIGDM
PMAMQVKLLRVLQERSFERVGGNSTIQADVRVIAATHRNLENMIEDDLFREDLYYRLNVFPIEMPSLQERKEDVPLLLQE
LMTRMEAEGGMPICFTPRAINSLMEHCWPGNVRELANLVERMVILYPNSLVDVNHLPTKYRYSDIPEFQPEFNNFASEEE
QERDALSDLFSEDFSFEQHDELADNANAPQDLPAEGVNLKELLADMEVNMINQALEAQGGIVARAADMLGMRRTTLVEKM
RKYNLQR

Specific function: Member of the two-component regulatory system ntrB/ntrC involved in the activation of nitrogen assimilatory genes such as glnA. NtrC is phosphorylated by ntrB and interacts with sigma-54 [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI87082117, Length=387, Percent_Identity=42.1188630490956, Blast_Score=273, Evalue=2e-74,
Organism=Escherichia coli, GI1788550, Length=335, Percent_Identity=42.9850746268657, Blast_Score=271, Evalue=6e-74,
Organism=Escherichia coli, GI1790437, Length=486, Percent_Identity=37.2427983539095, Blast_Score=260, Evalue=1e-70,
Organism=Escherichia coli, GI1789087, Length=359, Percent_Identity=41.2256267409471, Blast_Score=254, Evalue=1e-68,
Organism=Escherichia coli, GI1790299, Length=354, Percent_Identity=40.3954802259887, Blast_Score=253, Evalue=2e-68,
Organism=Escherichia coli, GI1788905, Length=228, Percent_Identity=53.0701754385965, Blast_Score=241, Evalue=6e-65,
Organism=Escherichia coli, GI1789233, Length=353, Percent_Identity=40.5099150141643, Blast_Score=240, Evalue=1e-64,
Organism=Escherichia coli, GI87082152, Length=231, Percent_Identity=47.1861471861472, Blast_Score=215, Evalue=5e-57,
Organism=Escherichia coli, GI87081872, Length=288, Percent_Identity=40.625, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI1786524, Length=252, Percent_Identity=43.6507936507937, Blast_Score=206, Evalue=3e-54,
Organism=Escherichia coli, GI1787583, Length=237, Percent_Identity=39.662447257384, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI1789828, Length=235, Percent_Identity=35.3191489361702, Blast_Score=145, Evalue=7e-36,
Organism=Escherichia coli, GI87081858, Length=338, Percent_Identity=28.1065088757396, Blast_Score=140, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR010114
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 54790; Mature: 54790

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQGLAKLLVVDDNAQNRHNLSTILEFVGESCEVISSEQAHKVDWSLQWAGCIIGSIKAKG
CCCCEEEEEECCCCCCHHHHHHHHHHHCCHHHHHCCCCCCCCCCEEEEHHHHHHHHHHCC
FALLNEKLVHVNHIPLLVIGKNDYPVEELTNFVGELELPLNYPQLSDALRHCKDFLGRKG
HHHHHHHHEEEECCCEEEECCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCC
VQILPSARKNTLFRSLVGQSVGIQEVRHLIEQVSSTEANVLILGESGTGKEVVARNVHYH
CEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHH
SKRRSGPFVPVNCGAIPPDLLESELFGHEKGAFTGAITARKGRFELAEGGTLFLDEIGDM
HHCCCCCEEEEECCCCCHHHHHHHHHCCCCCCEEEEEEECCCCEEECCCCEEEEHHHCCC
PMAMQVKLLRVLQERSFERVGGNSTIQADVRVIAATHRNLENMIEDDLFREDLYYRLNVF
CHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEE
PIEMPSLQERKEDVPLLLQELMTRMEAEGGMPICFTPRAINSLMEHCWPGNVRELANLVE
EECCCCHHHHHCCHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHCCCCCHHHHHHHHH
RMVILYPNSLVDVNHLPTKYRYSDIPEFQPEFNNFASEEEQERDALSDLFSEDFSFEQHD
HHHHHCCCCEEECCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHCCCCCHHH
ELADNANAPQDLPAEGVNLKELLADMEVNMINQALEAQGGIVARAADMLGMRRTTLVEKM
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
RKYNLQR
HHHCCCC
>Mature Secondary Structure
MQGLAKLLVVDDNAQNRHNLSTILEFVGESCEVISSEQAHKVDWSLQWAGCIIGSIKAKG
CCCCEEEEEECCCCCCHHHHHHHHHHHCCHHHHHCCCCCCCCCCEEEEHHHHHHHHHHCC
FALLNEKLVHVNHIPLLVIGKNDYPVEELTNFVGELELPLNYPQLSDALRHCKDFLGRKG
HHHHHHHHEEEECCCEEEECCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCC
VQILPSARKNTLFRSLVGQSVGIQEVRHLIEQVSSTEANVLILGESGTGKEVVARNVHYH
CEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHH
SKRRSGPFVPVNCGAIPPDLLESELFGHEKGAFTGAITARKGRFELAEGGTLFLDEIGDM
HHCCCCCEEEEECCCCCHHHHHHHHHCCCCCCEEEEEEECCCCEEECCCCEEEEHHHCCC
PMAMQVKLLRVLQERSFERVGGNSTIQADVRVIAATHRNLENMIEDDLFREDLYYRLNVF
CHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEE
PIEMPSLQERKEDVPLLLQELMTRMEAEGGMPICFTPRAINSLMEHCWPGNVRELANLVE
EECCCCHHHHHCCHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHCCCCCHHHHHHHHH
RMVILYPNSLVDVNHLPTKYRYSDIPEFQPEFNNFASEEEQERDALSDLFSEDFSFEQHD
HHHHHCCCCEEECCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHCCCCCHHH
ELADNANAPQDLPAEGVNLKELLADMEVNMINQALEAQGGIVARAADMLGMRRTTLVEKM
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
RKYNLQR
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2881918; 11481430; 8478331 [H]