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The map label for this gene is atoS [H]

Identifier: 218708820

GI number: 218708820

Start: 841449

End: 842489

Strand: Direct

Name: atoS [H]

Synonym: VS_0820

Alternate gene names: 218708820

Gene position: 841449-842489 (Clockwise)

Preceding gene: 218708819

Following gene: 218708821

Centisome position: 25.5

GC content: 45.92

Gene sequence:

>1041_bases
ATGCACCTATCTAACGAACCAGAAAATCAATCACATCTAGATTCTGTTGAGCAACAGGTTGAGCGCTATAAGCAAGTGCT
CGATGTTATGCCTGCGGGGGTCATCTTGTTAGATACGCATGGTGAAGTGAGAGAAGCGAATCCTGAAGCTCACCGTATTC
TCGGGGTTGAGCTGGTTGGCGAGAAATGGTTTTCGGTAATACAAAATGCCTTTGAACCAAGGGACGATGATGGGCATGAG
ATCTCATTGAAGAATGGGCGAAAAGTGCGCTTAGCGATTTCAGCCTCGACTACAGGTCAGCTTATTTTGATTACAGACCT
GACAGAAACCCGCCTACTGCAGTCTCGTGTGAGCGATCTTCAGCGTTTATCTTCACTCGGAAGAATGGTCGCTTCGCTTG
CCCATCAGGTTCGCACGCCACTTTCTAGTGCGATGCTGTATGCATCAAACCTTGCCGCGCCAAATTTGCCGCCGGCAACA
AAAACGCGTTTTCAATCTAAGCTGATGGATAGGTTGCATGATTTAGAGAAACAAGTGAATGACATGCTGTTGTTTGCCAA
AGGTGGCGACAACAAGGTGGTTAAGCCATTCACCATCGCGGAACTCATCATTGAGTTTCATCCTATGGTGGAGGCTGCGT
TAAAAAGCAACCAGATTGATTATTGTCAGGAAGTTGAAGATGAAAAGACTCAAATGTTTGGCAACGCCAATGCTATCGCT
TCTGCTTTAAGTAACCTAGTTTTGAACGCGGTTCAAATTGCTGGCAAGAAATCGCAGATTGATGTGTTTTTTAGACCCGT
AAACGGTGAACTTAAGATATCAGTGCAAGACAGTGGCCCCGGAGTGCCTAAAGAACTACAAGGTAAGATTATGGAACCTT
TCTTTACCACTCGTTCTCAAGGCACAGGTCTAGGTTTAGCGGTTGTACAAATGGTATGCCGAGCACATGAAGGTCGACTG
GAATTGATATCAGAAGAGGGTGACGGCGCATGCTTTACCATGTGCCTACCGTTGGAAAGAAGCTCTTCTTCTGAAGACTA
A

Upstream 100 bases:

>100_bases
GTCGAGTTGTTGCTTGCTTAACTATGTGATAAATATAGCAAATAGCCTGACTTGTGTTGTACATGTCAGGCTGTTTTAGT
ATTTGAGGCAAATTTTTGAC

Downstream 100 bases:

>100_bases
TAAGTTTTAACTGAATTTACACTGGAGAATCCTATGGCTCAAAGCAAAGTGTTAATCGTCGAAGATGATGAAGGTCTACG
CGAAGCCCTTGTCGATACAC

Product: Signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MHLSNEPENQSHLDSVEQQVERYKQVLDVMPAGVILLDTHGEVREANPEAHRILGVELVGEKWFSVIQNAFEPRDDDGHE
ISLKNGRKVRLAISASTTGQLILITDLTETRLLQSRVSDLQRLSSLGRMVASLAHQVRTPLSSAMLYASNLAAPNLPPAT
KTRFQSKLMDRLHDLEKQVNDMLLFAKGGDNKVVKPFTIAELIIEFHPMVEAALKSNQIDYCQEVEDEKTQMFGNANAIA
SALSNLVLNAVQIAGKKSQIDVFFRPVNGELKISVQDSGPGVPKELQGKIMEPFFTTRSQGTGLGLAVVQMVCRAHEGRL
ELISEEGDGACFTMCLPLERSSSSED

Sequences:

>Translated_346_residues
MHLSNEPENQSHLDSVEQQVERYKQVLDVMPAGVILLDTHGEVREANPEAHRILGVELVGEKWFSVIQNAFEPRDDDGHE
ISLKNGRKVRLAISASTTGQLILITDLTETRLLQSRVSDLQRLSSLGRMVASLAHQVRTPLSSAMLYASNLAAPNLPPAT
KTRFQSKLMDRLHDLEKQVNDMLLFAKGGDNKVVKPFTIAELIIEFHPMVEAALKSNQIDYCQEVEDEKTQMFGNANAIA
SALSNLVLNAVQIAGKKSQIDVFFRPVNGELKISVQDSGPGVPKELQGKIMEPFFTTRSQGTGLGLAVVQMVCRAHEGRL
ELISEEGDGACFTMCLPLERSSSSED
>Mature_346_residues
MHLSNEPENQSHLDSVEQQVERYKQVLDVMPAGVILLDTHGEVREANPEAHRILGVELVGEKWFSVIQNAFEPRDDDGHE
ISLKNGRKVRLAISASTTGQLILITDLTETRLLQSRVSDLQRLSSLGRMVASLAHQVRTPLSSAMLYASNLAAPNLPPAT
KTRFQSKLMDRLHDLEKQVNDMLLFAKGGDNKVVKPFTIAELIIEFHPMVEAALKSNQIDYCQEVEDEKTQMFGNANAIA
SALSNLVLNAVQIAGKKSQIDVFFRPVNGELKISVQDSGPGVPKELQGKIMEPFFTTRSQGTGLGLAVVQMVCRAHEGRL
ELISEEGDGACFTMCLPLERSSSSED

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=330, Percent_Identity=29.3939393939394, Blast_Score=141, Evalue=6e-35,
Organism=Escherichia coli, GI1790436, Length=240, Percent_Identity=30.4166666666667, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1790346, Length=239, Percent_Identity=28.4518828451883, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1786600, Length=336, Percent_Identity=22.9166666666667, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1790300, Length=352, Percent_Identity=24.7159090909091, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1786912, Length=230, Percent_Identity=28.2608695652174, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1786783, Length=223, Percent_Identity=24.2152466367713, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI145693157, Length=223, Percent_Identity=26.457399103139, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87082128, Length=220, Percent_Identity=26.3636363636364, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI87081816, Length=224, Percent_Identity=26.3392857142857, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 38143; Mature: 38143

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLSNEPENQSHLDSVEQQVERYKQVLDVMPAGVILLDTHGEVREANPEAHRILGVELVG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHCCCCHHHHEEEHHHHH
EKWFSVIQNAFEPRDDDGHEISLKNGRKVRLAISASTTGQLILITDLTETRLLQSRVSDL
HHHHHHHHHHCCCCCCCCCEEEECCCCEEEEEEEECCCCCEEEEECCHHHHHHHHHHHHH
QRLSSLGRMVASLAHQVRTPLSSAMLYASNLAAPNLPPATKTRFQSKLMDRLHDLEKQVN
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
DMLLFAKGGDNKVVKPFTIAELIIEFHPMVEAALKSNQIDYCQEVEDEKTQMFGNANAIA
HEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHH
SALSNLVLNAVQIAGKKSQIDVFFRPVNGELKISVQDSGPGVPKELQGKIMEPFFTTRSQ
HHHHHHHHHHHHHCCCCCCEEEEEEECCCEEEEEEECCCCCCCHHHHHHHHCHHHHCCCC
GTGLGLAVVQMVCRAHEGRLELISEEGDGACFTMCLPLERSSSSED
CCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEEEECCCCCCCCC
>Mature Secondary Structure
MHLSNEPENQSHLDSVEQQVERYKQVLDVMPAGVILLDTHGEVREANPEAHRILGVELVG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHCCCCHHHHEEEHHHHH
EKWFSVIQNAFEPRDDDGHEISLKNGRKVRLAISASTTGQLILITDLTETRLLQSRVSDL
HHHHHHHHHHCCCCCCCCCEEEECCCCEEEEEEEECCCCCEEEEECCHHHHHHHHHHHHH
QRLSSLGRMVASLAHQVRTPLSSAMLYASNLAAPNLPPATKTRFQSKLMDRLHDLEKQVN
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
DMLLFAKGGDNKVVKPFTIAELIIEFHPMVEAALKSNQIDYCQEVEDEKTQMFGNANAIA
HEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHH
SALSNLVLNAVQIAGKKSQIDVFFRPVNGELKISVQDSGPGVPKELQGKIMEPFFTTRSQ
HHHHHHHHHHHHHCCCCCCEEEEEEECCCEEEEEEECCCCCCCHHHHHHHHCHHHHCCCC
GTGLGLAVVQMVCRAHEGRLELISEEGDGACFTMCLPLERSSSSED
CCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]