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The map label for this gene is plsC [H]

Identifier: 218708657

GI number: 218708657

Start: 661765

End: 662532

Strand: Reverse

Name: plsC [H]

Synonym: VS_0635

Alternate gene names: 218708657

Gene position: 662532-661765 (Counterclockwise)

Preceding gene: 218708658

Following gene: 218708656

Centisome position: 20.08

GC content: 46.74

Gene sequence:

>768_bases
GTGCTTGCTGTTCTTCGTATTATTTTGGCTACGGTGTTTATTATTTTCACCACTCTATGTGCTTTTGTTTACTGCTTGTT
TAGCCCCAAAAACCCAAAGCATGTGTACGTTTTCTGTCGTTGGTTCAACCAGCTACAAAAGATCGTCGGTGTAAAACTGA
TGCAGCGCGGCCTAGACAATGCGCCGACATCAGAAAAAAGCGTCTACATCTCTAACCACCAAAGCATATTGGACTTTGTG
ACTGACCCTGGGATGCTAAGGCCTCGTACCGTTTCTTTAGGCAAGCGCGATTTGTTGTATGTGCCTTTCTTTGGTCTGCT
GTATTGGATCACCGGTAATATTTTAATTAACCGCGAAGACAAGTCCAAAGCACGCGATACCATCAAGCAAGTGGCGGAAG
CGATTCACCAGCGAGATCTGTCTGTTTGGGTTTACCCTGAAGGAACGCGCAGTAAAGGGCGTGGACTACTGCCATTCAAA
ACGGGCGCTTTTCGAATGGCGATTGAAGCTGGCGTACCTATCACCCCGATGTGTACCAGCACCACACACAATAAGGTTGA
CCTCAACCGAGTTAATAATGGCATTGTGATCACCGAGATGCTCAAACCTATCGATGTGTCTGGATACAAGATCAGCGACG
CTAGAGAATTAGCCAATCGCTGTCACGCAATTATGGCTGAAAAAATAGCAGAGCTTGATGCCGAAGTGGCTAGTATAGAG
GCACAGAAAAACCCAGAACTGGATTCAGACGGTTCTTCCGCGCGCTAA

Upstream 100 bases:

>100_bases
TATCACAGTTAATTGTTGCAATTCGGTTAAATAGAGTGAAAACTTCAAGCATCTAAAACTATTTAATCACTGCCATCTTG
CGGTGAGTAAGGAGTGAATT

Downstream 100 bases:

>100_bases
CAAGGTAGTTACAGAAGGAACAAGAACTAACTCGCAGCGAACCCACTGAGTCATCGCTCAGTTACTTAAAAAGACACTCA
ACGATCGCAACTCTCATTGT

Product: putative 1-acyl-sn-glycerol-3-phosphate acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT; Phosphatidic acid synthase; PA synthase [H]

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MLAVLRIILATVFIIFTTLCAFVYCLFSPKNPKHVYVFCRWFNQLQKIVGVKLMQRGLDNAPTSEKSVYISNHQSILDFV
TDPGMLRPRTVSLGKRDLLYVPFFGLLYWITGNILINREDKSKARDTIKQVAEAIHQRDLSVWVYPEGTRSKGRGLLPFK
TGAFRMAIEAGVPITPMCTSTTHNKVDLNRVNNGIVITEMLKPIDVSGYKISDARELANRCHAIMAEKIAELDAEVASIE
AQKNPELDSDGSSAR

Sequences:

>Translated_255_residues
MLAVLRIILATVFIIFTTLCAFVYCLFSPKNPKHVYVFCRWFNQLQKIVGVKLMQRGLDNAPTSEKSVYISNHQSILDFV
TDPGMLRPRTVSLGKRDLLYVPFFGLLYWITGNILINREDKSKARDTIKQVAEAIHQRDLSVWVYPEGTRSKGRGLLPFK
TGAFRMAIEAGVPITPMCTSTTHNKVDLNRVNNGIVITEMLKPIDVSGYKISDARELANRCHAIMAEKIAELDAEVASIE
AQKNPELDSDGSSAR
>Mature_255_residues
MLAVLRIILATVFIIFTTLCAFVYCLFSPKNPKHVYVFCRWFNQLQKIVGVKLMQRGLDNAPTSEKSVYISNHQSILDFV
TDPGMLRPRTVSLGKRDLLYVPFFGLLYWITGNILINREDKSKARDTIKQVAEAIHQRDLSVWVYPEGTRSKGRGLLPFK
TGAFRMAIEAGVPITPMCTSTTHNKVDLNRVNNGIVITEMLKPIDVSGYKISDARELANRCHAIMAEKIAELDAEVASIE
AQKNPELDSDGSSAR

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the 2 position. This enzyme can utilize either acyl-CoA or acyl-ACP as the fatty acyl donor [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=225, Percent_Identity=30.6666666666667, Blast_Score=121, Evalue=5e-28,
Organism=Homo sapiens, GI15100175, Length=225, Percent_Identity=30.6666666666667, Blast_Score=121, Evalue=5e-28,
Organism=Homo sapiens, GI6041665, Length=188, Percent_Identity=34.0425531914894, Blast_Score=116, Evalue=2e-26,
Organism=Escherichia coli, GI1789395, Length=241, Percent_Identity=51.8672199170125, Blast_Score=271, Evalue=3e-74,
Organism=Caenorhabditis elegans, GI17564032, Length=222, Percent_Identity=30.6306306306306, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17568319, Length=213, Percent_Identity=31.4553990610329, Blast_Score=102, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6320151, Length=231, Percent_Identity=29.004329004329, Blast_Score=102, Evalue=5e-23,
Organism=Drosophila melanogaster, GI281364648, Length=243, Percent_Identity=29.6296296296296, Blast_Score=123, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24582856, Length=243, Percent_Identity=29.6296296296296, Blast_Score=123, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24582854, Length=243, Percent_Identity=29.6296296296296, Blast_Score=123, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24641614, Length=202, Percent_Identity=31.1881188118812, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24641612, Length=202, Percent_Identity=31.1881188118812, Blast_Score=109, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 28619; Mature: 28619

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAVLRIILATVFIIFTTLCAFVYCLFSPKNPKHVYVFCRWFNQLQKIVGVKLMQRGLDN
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCC
APTSEKSVYISNHQSILDFVTDPGMLRPRTVSLGKRDLLYVPFFGLLYWITGNILINRED
CCCCCCEEEECCHHHHHHHHCCCCCCCCCEECCCCCCEEEHHHHHHHHHHHCCEEEECCH
KSKARDTIKQVAEAIHQRDLSVWVYPEGTRSKGRGLLPFKTGAFRMAIEAGVPITPMCTS
HHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCC
TTHNKVDLNRVNNGIVITEMLKPIDVSGYKISDARELANRCHAIMAEKIAELDAEVASIE
CCCCCEEHHHCCCCEEEEEHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQKNPELDSDGSSAR
CCCCCCCCCCCCCCC
>Mature Secondary Structure
MLAVLRIILATVFIIFTTLCAFVYCLFSPKNPKHVYVFCRWFNQLQKIVGVKLMQRGLDN
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCC
APTSEKSVYISNHQSILDFVTDPGMLRPRTVSLGKRDLLYVPFFGLLYWITGNILINRED
CCCCCCEEEECCHHHHHHHHCCCCCCCCCEECCCCCCEEEHHHHHHHHHHHCCEEEECCH
KSKARDTIKQVAEAIHQRDLSVWVYPEGTRSKGRGLLPFKTGAFRMAIEAGVPITPMCTS
HHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCC
TTHNKVDLNRVNNGIVITEMLKPIDVSGYKISDARELANRCHAIMAEKIAELDAEVASIE
CCCCCEEHHHCCCCEEEEEHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQKNPELDSDGSSAR
CCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1557036; 9278503 [H]