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The map label for this gene is yrbD [H]

Identifier: 218708655

GI number: 218708655

Start: 658198

End: 659745

Strand: Reverse

Name: yrbD [H]

Synonym: VS_0633

Alternate gene names: 218708655

Gene position: 659745-658198 (Counterclockwise)

Preceding gene: 218708656

Following gene: 218708649

Centisome position: 20.0

GC content: 45.03

Gene sequence:

>1548_bases
ATGCAGTCGTTCGTTGATTTTTTGAATGGAATAATCTGGAGCCCAGTACTTATCTACCTATGTTTAGGTGCAGGTTTGTT
CTACTCCATCATGACTCGATTTGTTCAAATCCGTCACTTCTTTGAAATGTGGCGCTTGCTACTTTCGGGTAAAAGCTCAT
CAAAAGGCATCTCGTCTTTCCAAGCTCTTGCCGTTTCGCTATCTGGCCGTGTAGGTACAGGTAACATTGCAGGTGTTGCT
GCCGCTATCGGTTTCGGTGGCCCAGGTGCAGTATTCTGGATGTGGGTGGTAGCTTTCTTTGGCGCGGCGACTGCTTACGC
AGAATCTACGCTGGCGCAAATCTATAAAGAAGAAGATGAAGGCCAGTTCCGTGGTGGTCCGGCTTACTACATTGAAAAAG
CAATGGGTCAGAAGTGGTACGCATGGATCTTCGCTATCGCGACTATTTTTGCATGTGGTATTTTGCTTCCAGGTGTTCAG
TCAAACAGTATAGGTAATGCTGTAGAAGCTGCATTTGGCTCAGGTGATATGATTGAAACAGCTATCGGTACATTCAGTTT
CGCTAAAATTTTCACTGGTACTGTTGTTGCTATCATCCTTGCTTTCATCATCTTTGGTGGTGTTAAACGTATCGCGAACT
TCACACAAATTGTCGTTCCATTCATGGCGTTGGCTTACATCATCATCGCATTCGTTATCATCCTACTAAACATCAGCCAA
GTTCCTGTTGTTTTCGGAATGATTCTGGGTGATGCATTCACTCCTATGGCAGGCTTTGGTGCTGCAATCGGTTGGGGTGT
TAAACGTGGTGTTTACTCAAACGAAGCAGGTCAAGGTACTGGTCCTCACGCGGCAGCTGCGGCAAGTGTTGATCACCCAG
CTCAGCAAGGTTTGGTTCAAGCGTTCTCTATCTACATTGATACTCTTCTAGTATGTTCTGCTACAGCGTTCATGATCATC
ATCACTGGTGCTTACAACGTTCACGGTGGCGCTGAAGGTGTATTCCTTGTTCAGAACCTAGCAGCAAACATCGGTGCGAA
TGGTCCTGTATTTACACAGCTTGCTATTGAAAGTGCACTGCCAGGCATTGGTAAGCCGTTCATCGCATTTGCTCTGTTCT
TCTTCGCATTTACAACGATTCTTGCTTACTACTACATCGCAGAAACGAATATTGCTTACCTACGTCGTACCATCAAGATC
CCTGGCATGATGTTCGTACTTAAGCTTGTTCTTATTAGTGCCGTTTTCTATGGCACCGTTAAAACAGCAAACCTTGCATG
GGCAATGGGTGATGTGGGTGTTGGCTTGATGGCATGGTTAAACATCGTTGGTATTCTGATCATATTCTTCATGTCTAAGC
CTGCGCTTAAGGCTTTAGCAGACTACGAAGAACAGCAGAAACAAGGTGTGACTGAGTACACATTCAACCCTGTAAAACTA
GGCATTAAAGGTGCTACTTACTGGGAAGAGAAATACAAGCGTAAAACTGGCAAGTCTCCTGAATCTGAAGTTGCAGACAG
TAAACCTGTAGAGCAACCTTCAGCTTAA

Upstream 100 bases:

>100_bases
AATCCTAATGCGCAGTTAAATAATTTAACACTCGGGTTACAAGTGAAGTATTGTGTTGTTCGAAAAATAATCATAAGCAA
AACTAACAGGGAAAATACTC

Downstream 100 bases:

>100_bases
GCTTGACTTAGCAAATAGATCGCTTTAACTCGCGCTATTAATAACGCATAAAAAAGGGGTTAGCCATTTCGGCTAACCCC
TTTTGTTTTGTTCATAAAAA

Product: sodium/alanine symporter

Products: Na (I) [Cytoplasm]; L-alanine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 515; Mature: 515

Protein sequence:

>515_residues
MQSFVDFLNGIIWSPVLIYLCLGAGLFYSIMTRFVQIRHFFEMWRLLLSGKSSSKGISSFQALAVSLSGRVGTGNIAGVA
AAIGFGGPGAVFWMWVVAFFGAATAYAESTLAQIYKEEDEGQFRGGPAYYIEKAMGQKWYAWIFAIATIFACGILLPGVQ
SNSIGNAVEAAFGSGDMIETAIGTFSFAKIFTGTVVAIILAFIIFGGVKRIANFTQIVVPFMALAYIIIAFVIILLNISQ
VPVVFGMILGDAFTPMAGFGAAIGWGVKRGVYSNEAGQGTGPHAAAAASVDHPAQQGLVQAFSIYIDTLLVCSATAFMII
ITGAYNVHGGAEGVFLVQNLAANIGANGPVFTQLAIESALPGIGKPFIAFALFFFAFTTILAYYYIAETNIAYLRRTIKI
PGMMFVLKLVLISAVFYGTVKTANLAWAMGDVGVGLMAWLNIVGILIIFFMSKPALKALADYEEQQKQGVTEYTFNPVKL
GIKGATYWEEKYKRKTGKSPESEVADSKPVEQPSA

Sequences:

>Translated_515_residues
MQSFVDFLNGIIWSPVLIYLCLGAGLFYSIMTRFVQIRHFFEMWRLLLSGKSSSKGISSFQALAVSLSGRVGTGNIAGVA
AAIGFGGPGAVFWMWVVAFFGAATAYAESTLAQIYKEEDEGQFRGGPAYYIEKAMGQKWYAWIFAIATIFACGILLPGVQ
SNSIGNAVEAAFGSGDMIETAIGTFSFAKIFTGTVVAIILAFIIFGGVKRIANFTQIVVPFMALAYIIIAFVIILLNISQ
VPVVFGMILGDAFTPMAGFGAAIGWGVKRGVYSNEAGQGTGPHAAAAASVDHPAQQGLVQAFSIYIDTLLVCSATAFMII
ITGAYNVHGGAEGVFLVQNLAANIGANGPVFTQLAIESALPGIGKPFIAFALFFFAFTTILAYYYIAETNIAYLRRTIKI
PGMMFVLKLVLISAVFYGTVKTANLAWAMGDVGVGLMAWLNIVGILIIFFMSKPALKALADYEEQQKQGVTEYTFNPVKL
GIKGATYWEEKYKRKTGKSPESEVADSKPVEQPSA
>Mature_515_residues
MQSFVDFLNGIIWSPVLIYLCLGAGLFYSIMTRFVQIRHFFEMWRLLLSGKSSSKGISSFQALAVSLSGRVGTGNIAGVA
AAIGFGGPGAVFWMWVVAFFGAATAYAESTLAQIYKEEDEGQFRGGPAYYIEKAMGQKWYAWIFAIATIFACGILLPGVQ
SNSIGNAVEAAFGSGDMIETAIGTFSFAKIFTGTVVAIILAFIIFGGVKRIANFTQIVVPFMALAYIIIAFVIILLNISQ
VPVVFGMILGDAFTPMAGFGAAIGWGVKRGVYSNEAGQGTGPHAAAAASVDHPAQQGLVQAFSIYIDTLLVCSATAFMII
ITGAYNVHGGAEGVFLVQNLAANIGANGPVFTQLAIESALPGIGKPFIAFALFFFAFTTILAYYYIAETNIAYLRRTIKI
PGMMFVLKLVLISAVFYGTVKTANLAWAMGDVGVGLMAWLNIVGILIIFFMSKPALKALADYEEQQKQGVTEYTFNPVKL
GIKGATYWEEKYKRKTGKSPESEVADSKPVEQPSA

Specific function: Unknown

COG id: COG1115

COG function: function code E; Na+/alanine symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:alanine (SAF) symporter family [H]

Homologues:

Organism=Escherichia coli, GI1786188, Length=492, Percent_Identity=36.1788617886179, Blast_Score=280, Evalue=2e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001463 [H]

Pfam domain/function: PF01235 Na_Ala_symp [H]

EC number: NA

Molecular weight: Translated: 55214; Mature: 55214

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: PS00873 NA_ALANINE_SYMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCHHHHHHHHHHCCCCCCHHCCCCCCCCCCCC
>Mature Secondary Structure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CCCCCHHHHHHHHHHCCCCCCHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; L-alanine [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + L-alanine [Periplasm] = Na (I) [Cytoplasm] + L-alanine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]