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The map label for this gene is tcpI [H]

Identifier: 218708617

GI number: 218708617

Start: 619175

End: 620593

Strand: Reverse

Name: tcpI [H]

Synonym: VS_0595

Alternate gene names: 218708617

Gene position: 620593-619175 (Counterclockwise)

Preceding gene: 218708618

Following gene: 218708615

Centisome position: 18.81

GC content: 42.35

Gene sequence:

>1419_bases
TTGCTATCAAGATTGTACGCTTCTAAATTTCTGACGAGCAATAAAACAGAAGATGCTCAGCGTGCTGAAAAAGAGTTTGC
CTCTGCCGCACTACTTGCAGAAACAATCGAATCTCAACTCATGTCGATGGAACAAATCAACTACTTAAACGATTTCACTA
GTGCCTTCAAAATTTACCGCAACACATTTTCAAAGATCGTTGACACTATAAACACGCGAAATGGCATCATTTCAGGGACT
CTTGATCTTGCTGGTGTTAATGCAGCAAAAACAATTGAAGAGATAAAGCTATCAACAAAGTCAGAGCAAGACTCTGTCGG
ACCTAATATGGTCGAGCGATTCTCTAACGCGCAATTTGTGCTTGGCGTTCTTTCAATTCTCGTTGTCGCTGCTTCTCTTA
GCATTGCCGTTTCGATTTACCGCAGTGTATGGAAAGTCGTTGGAGGAGAGCCAAGTGACATCCAAACAATTGTTGCCGAA
GTCGCCGCTGGTGATCTTTCAAAGCAGATTCCAATTACGGGTAAAGAAACCGGTATATACGCAAACATTTTGGAGATGCG
CCAAGAACTACGTCGAATCATCGATGGTTTCCACCAAATTTCAGATAATGTTTCAGCAGCCTCCGTTGAGCTAACCGCAG
TGATGAGCCAAACAGAAGGTAATGCTCAACAAGAACTGAGTCAAATGGAGCAAATCGCAACTGCTATCAATGAACTTTCT
AGTACTGCGAGTGAGGTTAGCCAGAATGCAGCTAGCGCAGAGAGCGCTGCAACTGGGGCAACGACAAATGTCAAAGATGG
CAGTGTTTCACTCGATGCATCAGATGATATATCACGAAAAGTTGAAGACTCGATCGAAGAAACATCAAACATCGTTAATC
AATTGCAAGAGTACTCGGTAGAGATCGGTAGTGTTATTGAAGTGATCAATTCAATTTCTGAGCAAACTAACTTACTTGCG
TTAAATGCAGCCATTGAAGCCGCTCGAGCGGGAGAGCAAGGCCGAGGCTTTGCGGTGGTAGCAGATGAAGTTCGTTCTCT
TGCCGCTAAAACACAACAATCAACGGTCGATATTCAAGAAATAATATCTCGCCTTCAGGCTCAAGCGAAAGATGCGAACC
AATTTATGCAATCCAACCTTTCGTTAGCAGAAGAATCTAGACAGTATAGCGAACAGCTTCGTGCTGCATTCGCCTCTATC
ACTGACTCTGTACAACTAATATCTGATATGAACACACAAGTAGCCACTGCGTCTGAAGAACAATCTGGCGTAACACAAGA
TATTTCACAAAATGTTTCTCTGACCTTTGATATTGTTCATCAAAATGTTTCAGGAATTGAGCAGAGCAAACAGGCAAGTG
AAGAACTCTCTTCATTAGCTGTTAAGCAAAAAGACTTGCTGAGTTTTTTCAAAATCTAA

Upstream 100 bases:

>100_bases
TGCGTGAGGCAGTGACCAACCTAATGACCCAAGCTTCAGCTGAAGAGCTGAAGAAGATTTAGAAGTTGCTGTCAGTTCAG
GACAGCTTCAGCAGCATGTA

Downstream 100 bases:

>100_bases
CGTTATAGTAAAATAGATAAATAAGCTTCTAACGCCACTATATTTGTGGCGTTTTTCTTCTCAAATGAACAAACAAAAAG
AGCAGCCAAATCGCTGCTCT

Product: hypothetical protein

Products: NA

Alternate protein names: TCP pilus biosynthesis protein tcpI [H]

Number of amino acids: Translated: 472; Mature: 472

Protein sequence:

>472_residues
MLSRLYASKFLTSNKTEDAQRAEKEFASAALLAETIESQLMSMEQINYLNDFTSAFKIYRNTFSKIVDTINTRNGIISGT
LDLAGVNAAKTIEEIKLSTKSEQDSVGPNMVERFSNAQFVLGVLSILVVAASLSIAVSIYRSVWKVVGGEPSDIQTIVAE
VAAGDLSKQIPITGKETGIYANILEMRQELRRIIDGFHQISDNVSAASVELTAVMSQTEGNAQQELSQMEQIATAINELS
STASEVSQNAASAESAATGATTNVKDGSVSLDASDDISRKVEDSIEETSNIVNQLQEYSVEIGSVIEVINSISEQTNLLA
LNAAIEAARAGEQGRGFAVVADEVRSLAAKTQQSTVDIQEIISRLQAQAKDANQFMQSNLSLAEESRQYSEQLRAAFASI
TDSVQLISDMNTQVATASEEQSGVTQDISQNVSLTFDIVHQNVSGIEQSKQASEELSSLAVKQKDLLSFFKI

Sequences:

>Translated_472_residues
MLSRLYASKFLTSNKTEDAQRAEKEFASAALLAETIESQLMSMEQINYLNDFTSAFKIYRNTFSKIVDTINTRNGIISGT
LDLAGVNAAKTIEEIKLSTKSEQDSVGPNMVERFSNAQFVLGVLSILVVAASLSIAVSIYRSVWKVVGGEPSDIQTIVAE
VAAGDLSKQIPITGKETGIYANILEMRQELRRIIDGFHQISDNVSAASVELTAVMSQTEGNAQQELSQMEQIATAINELS
STASEVSQNAASAESAATGATTNVKDGSVSLDASDDISRKVEDSIEETSNIVNQLQEYSVEIGSVIEVINSISEQTNLLA
LNAAIEAARAGEQGRGFAVVADEVRSLAAKTQQSTVDIQEIISRLQAQAKDANQFMQSNLSLAEESRQYSEQLRAAFASI
TDSVQLISDMNTQVATASEEQSGVTQDISQNVSLTFDIVHQNVSGIEQSKQASEELSSLAVKQKDLLSFFKI
>Mature_472_residues
MLSRLYASKFLTSNKTEDAQRAEKEFASAALLAETIESQLMSMEQINYLNDFTSAFKIYRNTFSKIVDTINTRNGIISGT
LDLAGVNAAKTIEEIKLSTKSEQDSVGPNMVERFSNAQFVLGVLSILVVAASLSIAVSIYRSVWKVVGGEPSDIQTIVAE
VAAGDLSKQIPITGKETGIYANILEMRQELRRIIDGFHQISDNVSAASVELTAVMSQTEGNAQQELSQMEQIATAINELS
STASEVSQNAASAESAATGATTNVKDGSVSLDASDDISRKVEDSIEETSNIVNQLQEYSVEIGSVIEVINSISEQTNLLA
LNAAIEAARAGEQGRGFAVVADEVRSLAAKTQQSTVDIQEIISRLQAQAKDANQFMQSNLSLAEESRQYSEQLRAAFASI
TDSVQLISDMNTQVATASEEQSGVTQDISQNVSLTFDIVHQNVSGIEQSKQASEELSSLAVKQKDLLSFFKI

Specific function: May function as an environmental regulator of TCP biogenesis. Negatively regulates the synthesis of the major pilin subunit of TCP (tcpA) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=360, Percent_Identity=30.5555555555556, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1788195, Length=289, Percent_Identity=30.4498269896194, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1787690, Length=321, Percent_Identity=28.9719626168224, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI2367378, Length=316, Percent_Identity=30.379746835443, Blast_Score=105, Evalue=8e-24,
Organism=Escherichia coli, GI1789453, Length=274, Percent_Identity=29.5620437956204, Blast_Score=92, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004089 [H]

Pfam domain/function: PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 50899; Mature: 50899

Theoretical pI: Translated: 4.19; Mature: 4.19

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSRLYASKFLTSNKTEDAQRAEKEFASAALLAETIESQLMSMEQINYLNDFTSAFKIYR
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NTFSKIVDTINTRNGIISGTLDLAGVNAAKTIEEIKLSTKSEQDSVGPNMVERFSNAQFV
HHHHHHHHHHHCCCCCEECCHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCHHH
LGVLSILVVAASLSIAVSIYRSVWKVVGGEPSDIQTIVAEVAAGDLSKQIPITGKETGIY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
ANILEMRQELRRIIDGFHQISDNVSAASVELTAVMSQTEGNAQQELSQMEQIATAINELS
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
STASEVSQNAASAESAATGATTNVKDGSVSLDASDDISRKVEDSIEETSNIVNQLQEYSV
HHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EIGSVIEVINSISEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLAAKTQQSTVDIQE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHCCCHHH
IISRLQAQAKDANQFMQSNLSLAEESRQYSEQLRAAFASITDSVQLISDMNTQVATASEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHH
QSGVTQDISQNVSLTFDIVHQNVSGIEQSKQASEELSSLAVKQKDLLSFFKI
HCCCHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLSRLYASKFLTSNKTEDAQRAEKEFASAALLAETIESQLMSMEQINYLNDFTSAFKIYR
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NTFSKIVDTINTRNGIISGTLDLAGVNAAKTIEEIKLSTKSEQDSVGPNMVERFSNAQFV
HHHHHHHHHHHCCCCCEECCHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCHHH
LGVLSILVVAASLSIAVSIYRSVWKVVGGEPSDIQTIVAEVAAGDLSKQIPITGKETGIY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
ANILEMRQELRRIIDGFHQISDNVSAASVELTAVMSQTEGNAQQELSQMEQIATAINELS
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
STASEVSQNAASAESAATGATTNVKDGSVSLDASDDISRKVEDSIEETSNIVNQLQEYSV
HHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EIGSVIEVINSISEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLAAKTQQSTVDIQE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHCCCHHH
IISRLQAQAKDANQFMQSNLSLAEESRQYSEQLRAAFASITDSVQLISDMNTQVATASEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHH
QSGVTQDISQNVSLTFDIVHQNVSGIEQSKQASEELSSLAVKQKDLLSFFKI
HCCCHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8005659 [H]