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The map label for this gene is ygcN

Identifier: 218696365

GI number: 218696365

Start: 3108645

End: 3109916

Strand: Direct

Name: ygcN

Synonym: EC55989_3040

Alternate gene names: 218696365

Gene position: 3108645-3109916 (Clockwise)

Preceding gene: 218696364

Following gene: 218696366

Centisome position: 60.31

GC content: 55.66

Gene sequence:

>1272_bases
ATGGAAGACGACTGCGACATTATTATTATTGGTGCCGGTATTGCAGGCACCGCTTGCGCGTTACGCTGCGCGCGAGCGGG
TTTATCCGTTTTGTTACTGGAACGCGCTGAAATCCCCGGCAGCAAAAATCTTTCCGGCGGGCGGTTATATACCCATGCAC
TCGCGGAACTCCTCCCTCAGTTTCATCTGACCGCGCCTCTTGAACGATGCATCACTCACGAAAGCCTTTCCCTGTTAACG
CCGGATGGCGCAACGACGTTTTCCAGCTTACAGCCCGGCGGTGAATCCTGGAGTGTATTACGTGCACGGTTCGATCCGTG
GCTGGTTGCCGAAGCCGAAAAAGAAGGTGTCGAATGCATCCCTGGTGCGACGGTGGATGCACTGTATGAAGAAAACGGCA
GGGTGTGTGGTGTCATTTGTGGTGACGATATTCTCCGCGCCCGTTATGTGGTGCTGGCAGAAGGTGCCAACAGCGTCCTG
GCTGAGCGTCACGGGTTAGTGACTCGTCCTGCTGGCGAAGCGATGGCGTTGGGGATCAAAGAAGTGCTGTCGCTGGAAAC
ATCCGCTATTGAAGAACGTTTTCATCTGGAGAATAACGAAGGCGCAGCGTTGCTGTTCAGCGGCGGGATCTGTGATGACT
TACCCGGCGGCGCATTTCTTTATACTAATCAACAAACGCTCTCGTTAGGGATTGTTTGCCCGCTCTCTTCCCTTACGCAA
AGCCGTGTTCCGGCAAGCGAGCTGCTGACTCGCTTTAAAGCGCATCCGGCAGTGCGCCCGCTTATCAAAAACACGGAATC
ACTGGAGTATGGTGCGCATCTGGTGCCAGAAGGTGGCTTGCACAGTATGCCGGTGCAATACGCCGGTAACGGCTGGCTGC
TGGTGGGCGATGCGTTGCGCAGTTGCGTCAATACCGGAATTTCCGTGCGCGGCATGGATATGGCGCTGACTGGCGCGCAG
GCGGCGGCACAAACGCTGATAAGCGCCTGCCAGCACCGCGAGCCGCAAAATCTGTTTCCGCTTTATCATCACAACGTAGA
GCGCAGCCTGCTGTGGGATGTTCTACAGCGTTATCAGCATGTTCCGGCGCTTTTGCAACGCCCGGGATGGTACCGTACGT
GGCCTGCGTTAATGCAGGATATTTCCCGCGATTTATGGGATCAGGGTGATAAACCTGTTCCACCGCTGCGCCAGTTATTC
TGGCATCATTTACGTCGTCACGGCCTGTGGCATCTGGCGGGCGATGTTATCAGGAGTCTGCGATGTCTGTAG

Upstream 100 bases:

>100_bases
GTTGTATCTATCGCGGCGAATGATAAGAGTGTGTCGGCGGTCAATTTCCCTTAAGTAACGCTATGTTAGGGTGTTGTGTT
CTGGATATCTGGGGCATGAC

Downstream 100 bases:

>100_bases
CCCGTAATCTCTGGCGCGTTGCTGATGCGCCGCACATTGTTCCGGCTGACTCCGTTGAGCGCCAGACGGCAGAACGGTTG
ATTAGCGCCTGTCCGGCAGG

Product: putative oxidoreductase with FAD/NAD(P)-binding domain

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MEDDCDIIIIGAGIAGTACALRCARAGLSVLLLERAEIPGSKNLSGGRLYTHALAELLPQFHLTAPLERCITHESLSLLT
PDGATTFSSLQPGGESWSVLRARFDPWLVAEAEKEGVECIPGATVDALYEENGRVCGVICGDDILRARYVVLAEGANSVL
AERHGLVTRPAGEAMALGIKEVLSLETSAIEERFHLENNEGAALLFSGGICDDLPGGAFLYTNQQTLSLGIVCPLSSLTQ
SRVPASELLTRFKAHPAVRPLIKNTESLEYGAHLVPEGGLHSMPVQYAGNGWLLVGDALRSCVNTGISVRGMDMALTGAQ
AAAQTLISACQHREPQNLFPLYHHNVERSLLWDVLQRYQHVPALLQRPGWYRTWPALMQDISRDLWDQGDKPVPPLRQLF
WHHLRRHGLWHLAGDVIRSLRCL

Sequences:

>Translated_423_residues
MEDDCDIIIIGAGIAGTACALRCARAGLSVLLLERAEIPGSKNLSGGRLYTHALAELLPQFHLTAPLERCITHESLSLLT
PDGATTFSSLQPGGESWSVLRARFDPWLVAEAEKEGVECIPGATVDALYEENGRVCGVICGDDILRARYVVLAEGANSVL
AERHGLVTRPAGEAMALGIKEVLSLETSAIEERFHLENNEGAALLFSGGICDDLPGGAFLYTNQQTLSLGIVCPLSSLTQ
SRVPASELLTRFKAHPAVRPLIKNTESLEYGAHLVPEGGLHSMPVQYAGNGWLLVGDALRSCVNTGISVRGMDMALTGAQ
AAAQTLISACQHREPQNLFPLYHHNVERSLLWDVLQRYQHVPALLQRPGWYRTWPALMQDISRDLWDQGDKPVPPLRQLF
WHHLRRHGLWHLAGDVIRSLRCL
>Mature_423_residues
MEDDCDIIIIGAGIAGTACALRCARAGLSVLLLERAEIPGSKNLSGGRLYTHALAELLPQFHLTAPLERCITHESLSLLT
PDGATTFSSLQPGGESWSVLRARFDPWLVAEAEKEGVECIPGATVDALYEENGRVCGVICGDDILRARYVVLAEGANSVL
AERHGLVTRPAGEAMALGIKEVLSLETSAIEERFHLENNEGAALLFSGGICDDLPGGAFLYTNQQTLSLGIVCPLSSLTQ
SRVPASELLTRFKAHPAVRPLIKNTESLEYGAHLVPEGGLHSMPVQYAGNGWLLVGDALRSCVNTGISVRGMDMALTGAQ
AAAQTLISACQHREPQNLFPLYHHNVERSLLWDVLQRYQHVPALLQRPGWYRTWPALMQDISRDLWDQGDKPVPPLRQLF
WHHLRRHGLWHLAGDVIRSLRCL

Specific function: Probably accepts electrons from ygcQ/ygcR and reduces a quinone [H]

COG id: COG0644

COG function: function code C; Dehydrogenases (flavoproteins)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF-QO/fixC family [H]

Homologues:

Organism=Homo sapiens, GI119703746, Length=400, Percent_Identity=24.75, Blast_Score=86, Evalue=6e-17,
Organism=Escherichia coli, GI87082155, Length=423, Percent_Identity=99.290780141844, Blast_Score=852, Evalue=0.0,
Organism=Escherichia coli, GI1787991, Length=428, Percent_Identity=42.2897196261682, Blast_Score=339, Evalue=2e-94,
Organism=Escherichia coli, GI1786227, Length=428, Percent_Identity=40.6542056074766, Blast_Score=329, Evalue=3e-91,
Organism=Caenorhabditis elegans, GI25144720, Length=397, Percent_Identity=25.9445843828715, Blast_Score=99, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6324932, Length=367, Percent_Identity=26.7029972752044, Blast_Score=87, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24652256, Length=407, Percent_Identity=25.7985257985258, Blast_Score=96, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR003042 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: 1.5.5.-

Molecular weight: Translated: 46214; Mature: 46214

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDDCDIIIIGAGIAGTACALRCARAGLSVLLLERAEIPGSKNLSGGRLYTHALAELLPQ
CCCCCCEEEEECCCHHHHHHHHHHHHCHHEEEEEHHCCCCCCCCCCCHHHHHHHHHHHHH
FHLTAPLERCITHESLSLLTPDGATTFSSLQPGGESWSVLRARFDPWLVAEAEKEGVECI
HHCHHHHHHHHHHCCCEEECCCCCCHHHCCCCCCCCHHHHHHHCCCEEEEECCCCCCEEC
PGATVDALYEENGRVCGVICGDDILRARYVVLAEGANSVLAERHGLVTRPAGEAMALGIK
CCCHHHHHHHCCCCEEEEEECCHHHHHEEEEEECCCHHHHHHHCCCEECCCCHHHHHHHH
EVLSLETSAIEERFHLENNEGAALLFSGGICDDLPGGAFLYTNQQTLSLGIVCPLSSLTQ
HHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCEEEEECCCEEEEEEECCHHHHHH
SRVPASELLTRFKAHPAVRPLIKNTESLEYGAHLVPEGGLHSMPVQYAGNGWLLVGDALR
HCCCHHHHHHHHHCCCCHHHHHCCCCCCCCCCEECCCCCCCCCCEEECCCCEEEEHHHHH
SCVNTGISVRGMDMALTGAQAAAQTLISACQHREPQNLFPLYHHNVERSLLWDVLQRYQH
HHHHCCCEEECCCEEECCHHHHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHHHHHHHHH
VPALLQRPGWYRTWPALMQDISRDLWDQGDKPVPPLRQLFWHHLRRHGLWHLAGDVIRSL
HHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHH
RCL
HCC
>Mature Secondary Structure
MEDDCDIIIIGAGIAGTACALRCARAGLSVLLLERAEIPGSKNLSGGRLYTHALAELLPQ
CCCCCCEEEEECCCHHHHHHHHHHHHCHHEEEEEHHCCCCCCCCCCCHHHHHHHHHHHHH
FHLTAPLERCITHESLSLLTPDGATTFSSLQPGGESWSVLRARFDPWLVAEAEKEGVECI
HHCHHHHHHHHHHCCCEEECCCCCCHHHCCCCCCCCHHHHHHHCCCEEEEECCCCCCEEC
PGATVDALYEENGRVCGVICGDDILRARYVVLAEGANSVLAERHGLVTRPAGEAMALGIK
CCCHHHHHHHCCCCEEEEEECCHHHHHEEEEEECCCHHHHHHHCCCEECCCCHHHHHHHH
EVLSLETSAIEERFHLENNEGAALLFSGGICDDLPGGAFLYTNQQTLSLGIVCPLSSLTQ
HHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCEEEEECCCEEEEEEECCHHHHHH
SRVPASELLTRFKAHPAVRPLIKNTESLEYGAHLVPEGGLHSMPVQYAGNGWLLVGDALR
HCCCHHHHHHHHHCCCCHHHHHCCCCCCCCCCEECCCCCCCCCCEEECCCCEEEEHHHHH
SCVNTGISVRGMDMALTGAQAAAQTLISACQHREPQNLFPLYHHNVERSLLWDVLQRYQH
HHHHCCCEEECCCEEECCHHHHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHHHHHHHHH
VPALLQRPGWYRTWPALMQDISRDLWDQGDKPVPPLRQLFWHHLRRHGLWHLAGDVIRSL
HHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHH
RCL
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]