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The map label for this gene is yiaN [H]

Identifier: 218691868

GI number: 218691868

Start: 4186672

End: 4188147

Strand: Direct

Name: yiaN [H]

Synonym: ECED1_4267

Alternate gene names: 218691868

Gene position: 4186672-4188147 (Clockwise)

Preceding gene: 218691867

Following gene: 218691869

Centisome position: 80.37

GC content: 50.54

Gene sequence:

>1476_bases
GTGTCTGGGGCTGGCCTGGGGCGCTATAGAAAAAACAGCGCAAGACTGGAGCAACTTATCGCCCATTCTTGGCGTCCCCA
TTGGCTTAATGTACGCCGCCGCTATCCCCACCAGTCTGATTATCGCATTGCTGGAATTGCGTCACTTATACCGGCAGTTC
ACAAATACCCCCAGCCGAAACCAACAAGGAGCCTGACGATGACAATCCTTATATTTATTGTCAGTTTGTTAGGGGCTATC
GCAATTGGCGTTCCCATCGCCTGGGCATTATTACTGTGCGGCATTTCATTGATGTTCTGGATGGATATCTTTGATGTGCA
AATTCTGGCACAAACGTTGGTAAATGGCGCAGACAGCTTCTCCCTGTTAGCCATCCCCTTCTTTGTACTGGCGGGTGAGA
TCATGAACGCGGGCGGCCTGTCGCAACGTATCGTCGACTTGCCAATGAAACTGGTAGGCCACAGGCCAGGCGGTCTGGGT
TACGTGGGCGTGCTGGCAGCGATGATCATGGCAAGCCTGTCCGGTTCTGCGGTTGCTGATACCGCAGCTGTCGCGGCGCT
GCTGGTGCCGATGATGCGCCAGGCCAACTATCCGGTAAACCGCGCCGCCGGGCTTATCGGTTCCGGGGGGATTATTGCGG
CCATTATCCCGCCTTCCATACCACTCATTATCTTCGGCGTCTCCAGCGGACTCTCCATCAGCAAACTGTTTATGGCGGGC
ATTGCGCCAGGCATCATGATGGGCGTCACGCTGATGGTTACCTGGTGGTGGCAGGCAAAACGACTGAATTTACCTTGTCA
GCCGAAAGCCTCACTGCGAGAAGTCTGGCAATCCTTAGTTTCCGGTATTTGGGCGCTCTTTTTACCGATAATTATTATTG
GCGGTTTCCGTTCGGGGTTATTTACACCGACCGAAGCAGGCGCGGTTGCCGCCTTCTACGCTCTGTTCGTCTCGGTGGTG
GTCTATCGCGAGATGACCTTCTCCACGCTTTATCATGTGCTGATTAACGCGGCAAAAACCACATCCGTGGTGATGTTCCT
GGTGGCCTCTGCTGCGGTATCTGCATGGCTTATTACGATCGCCGAATTACCCATGATGGTATCGGAGCTATTACAACCGT
TGGTTGATTCGCCTCGCTTATTATTCATCGTCATTATGCTCGCTATTATGGTGATCAGTACGGTCATGGACTTAACGCCT
ACCGTATTAATTCTTACACCAGTATTAATGCCATTAGTGAAAGAAGCGGGAATAGATCCGGTCTATTTCGGCATCATGTT
TATTATCAACTGTTCAATATCACTGATTACGCCTCCAGTCGGTAATGTTCTTAACGTGGTATGCGGCGTGGCGAAACTTA
AATTTGACGATGCGGTAAAAGGCGTTGCGCCTTACGTCATGGTTTTATTCATGTTGTTAGCATTATTTATTTTTATACCG
GAGCTCATTACCGCTCCTCTTAAATGGATGAGTTAA

Upstream 100 bases:

>100_bases
TGGACAACAGCCATGTGCAGGTTACTTTTTTAGTCGAAAAACTCTCACCGGCTAATCAACAACGTGTTTCGCTGCTAACC
CATACGCTCATTTTATTGCT

Downstream 100 bases:

>100_bases
AAGGAAATCATAATGAAATTACGTTCTGTAACCTACGCTTTATTAATTGCCGGAGTGGCGACGTTCAGCACATCTTCTCT
GGCGGCACAATCATTACGTT

Product: transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 491; Mature: 490

Protein sequence:

>491_residues
MSGAGLGRYRKNSARLEQLIAHSWRPHWLNVRRRYPHQSDYRIAGIASLIPAVHKYPQPKPTRSLTMTILIFIVSLLGAI
AIGVPIAWALLLCGISLMFWMDIFDVQILAQTLVNGADSFSLLAIPFFVLAGEIMNAGGLSQRIVDLPMKLVGHRPGGLG
YVGVLAAMIMASLSGSAVADTAAVAALLVPMMRQANYPVNRAAGLIGSGGIIAAIIPPSIPLIIFGVSSGLSISKLFMAG
IAPGIMMGVTLMVTWWWQAKRLNLPCQPKASLREVWQSLVSGIWALFLPIIIIGGFRSGLFTPTEAGAVAAFYALFVSVV
VYREMTFSTLYHVLINAAKTTSVVMFLVASAAVSAWLITIAELPMMVSELLQPLVDSPRLLFIVIMLAIMVISTVMDLTP
TVLILTPVLMPLVKEAGIDPVYFGIMFIINCSISLITPPVGNVLNVVCGVAKLKFDDAVKGVAPYVMVLFMLLALFIFIP
ELITAPLKWMS

Sequences:

>Translated_491_residues
MSGAGLGRYRKNSARLEQLIAHSWRPHWLNVRRRYPHQSDYRIAGIASLIPAVHKYPQPKPTRSLTMTILIFIVSLLGAI
AIGVPIAWALLLCGISLMFWMDIFDVQILAQTLVNGADSFSLLAIPFFVLAGEIMNAGGLSQRIVDLPMKLVGHRPGGLG
YVGVLAAMIMASLSGSAVADTAAVAALLVPMMRQANYPVNRAAGLIGSGGIIAAIIPPSIPLIIFGVSSGLSISKLFMAG
IAPGIMMGVTLMVTWWWQAKRLNLPCQPKASLREVWQSLVSGIWALFLPIIIIGGFRSGLFTPTEAGAVAAFYALFVSVV
VYREMTFSTLYHVLINAAKTTSVVMFLVASAAVSAWLITIAELPMMVSELLQPLVDSPRLLFIVIMLAIMVISTVMDLTP
TVLILTPVLMPLVKEAGIDPVYFGIMFIINCSISLITPPVGNVLNVVCGVAKLKFDDAVKGVAPYVMVLFMLLALFIFIP
ELITAPLKWMS
>Mature_490_residues
SGAGLGRYRKNSARLEQLIAHSWRPHWLNVRRRYPHQSDYRIAGIASLIPAVHKYPQPKPTRSLTMTILIFIVSLLGAIA
IGVPIAWALLLCGISLMFWMDIFDVQILAQTLVNGADSFSLLAIPFFVLAGEIMNAGGLSQRIVDLPMKLVGHRPGGLGY
VGVLAAMIMASLSGSAVADTAAVAALLVPMMRQANYPVNRAAGLIGSGGIIAAIIPPSIPLIIFGVSSGLSISKLFMAGI
APGIMMGVTLMVTWWWQAKRLNLPCQPKASLREVWQSLVSGIWALFLPIIIIGGFRSGLFTPTEAGAVAAFYALFVSVVV
YREMTFSTLYHVLINAAKTTSVVMFLVASAAVSAWLITIAELPMMVSELLQPLVDSPRLLFIVIMLAIMVISTVMDLTPT
VLILTPVLMPLVKEAGIDPVYFGIMFIINCSISLITPPVGNVLNVVCGVAKLKFDDAVKGVAPYVMVLFMLLALFIFIPE
LITAPLKWMS

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system yiaMNO involved in the uptake of 2,3- diketo-L-gulonate [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=425, Percent_Identity=84.9411764705882, Blast_Score=661, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM [H]

EC number: NA

Molecular weight: Translated: 52974; Mature: 52843

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGAGLGRYRKNSARLEQLIAHSWRPHWLNVRRRYPHQSDYRIAGIASLIPAVHKYPQPK
CCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCC
PTRSLTMTILIFIVSLLGAIAIGVPIAWALLLCGISLMFWMDIFDVQILAQTLVNGADSF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
SLLAIPFFVLAGEIMNAGGLSQRIVDLPMKLVGHRPGGLGYVGVLAAMIMASLSGSAVAD
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHH
TAAVAALLVPMMRQANYPVNRAAGLIGSGGIIAAIIPPSIPLIIFGVSSGLSISKLFMAG
HHHHHHHHHHHHHHCCCCHHHHCCCCCCCCEEEEECCCCCCEEEEECCCCCHHHHHHHHH
IAPGIMMGVTLMVTWWWQAKRLNLPCQPKASLREVWQSLVSGIWALFLPIIIIGGFRSGL
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
FTPTEAGAVAAFYALFVSVVVYREMTFSTLYHVLINAAKTTSVVMFLVASAAVSAWLITI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AELPMMVSELLQPLVDSPRLLFIVIMLAIMVISTVMDLTPTVLILTPVLMPLVKEAGIDP
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
VYFGIMFIINCSISLITPPVGNVLNVVCGVAKLKFDDAVKGVAPYVMVLFMLLALFIFIP
HHHHHHHHHHCCHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELITAPLKWMS
HHHHHHHHCCC
>Mature Secondary Structure 
SGAGLGRYRKNSARLEQLIAHSWRPHWLNVRRRYPHQSDYRIAGIASLIPAVHKYPQPK
CCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCC
PTRSLTMTILIFIVSLLGAIAIGVPIAWALLLCGISLMFWMDIFDVQILAQTLVNGADSF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
SLLAIPFFVLAGEIMNAGGLSQRIVDLPMKLVGHRPGGLGYVGVLAAMIMASLSGSAVAD
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHH
TAAVAALLVPMMRQANYPVNRAAGLIGSGGIIAAIIPPSIPLIIFGVSSGLSISKLFMAG
HHHHHHHHHHHHHHCCCCHHHHCCCCCCCCEEEEECCCCCCEEEEECCCCCHHHHHHHHH
IAPGIMMGVTLMVTWWWQAKRLNLPCQPKASLREVWQSLVSGIWALFLPIIIIGGFRSGL
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
FTPTEAGAVAAFYALFVSVVVYREMTFSTLYHVLINAAKTTSVVMFLVASAAVSAWLITI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AELPMMVSELLQPLVDSPRLLFIVIMLAIMVISTVMDLTPTVLILTPVLMPLVKEAGIDP
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
VYFGIMFIINCSISLITPPVGNVLNVVCGVAKLKFDDAVKGVAPYVMVLFMLLALFIFIP
HHHHHHHHHHCCHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELITAPLKWMS
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503 [H]