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The map label for this gene is secF

Identifier: 218688272

GI number: 218688272

Start: 450490

End: 451461

Strand: Direct

Name: secF

Synonym: ECED1_0432

Alternate gene names: 218688272

Gene position: 450490-451461 (Clockwise)

Preceding gene: 218688271

Following gene: 218688273

Centisome position: 8.65

GC content: 51.65

Gene sequence:

>972_bases
GTGGCACAGGAATATACTGTTGAACAACTAAACCACGGCCGTAAAGTCTATGACTTTATGCGCTGGGACTACTGGGCTTT
CGGCATCTCTGGTCTGCTGTTAATCGCCGCTATCGTTATTATGGGCGTGCGCGGCTTTAACTGGGGGCTGGATTTTACCG
GTGGTACGGTTATTGAAATTACGCTCGAAAAACCAGCTGAAATTGACGTAATGCGTGATGCATTGCAAAAAGCCGGTTTT
GAAGAGCCGATGCTGCAAAACTTTGGTAGCAGCCACGACATCATGGTCCGTATGCCGCCTGCTGAAGGCGAAACCGGCGG
TCAGGTGTTGGGCAGCCAGGTTCTGAAGGTGATTAACGAATCCACCAATCAGAATGCGGCAGTGAAGCGTATTGAGTTCG
TCGGTCCGAGCGTGGGGGCAGACCTTGCGCAAACCGGTGCGATGGCGTTGATGGCGGCGCTGCTGTCTATCCTCGTGTAC
GTAGGTTTCCGCTTTGAGTGGCGACTGGCGGCAGGGGTTGTTATTGCGCTGGCGCACGACGTTATCATTACGCTGGGTAT
TTTGTCGTTATTCCATATCGAGATTGACCTGACCATTGTGGCATCATTGATGTCGGTTATCGGTTACTCGCTTAACGACA
GTATCGTGGTATCGGACCGTATTCGTGAAAACTTCCGCAAGATCCGTCGCGGTACGCCTTACGAAATCTTTAACGTGTCC
TTGACCCAGACGCTGCACCGTACCTTGATCACATCCGGTACTACCTTGATGGTTATCCTGATGCTGTACCTCTTCGGTGG
TCCGGTACTGGAAGGCTTCTCGCTGACCATGCTTATCGGTGTTTCCATCGGTACTGCATCTTCCATCTATGTGGCATCTG
CGCTGGCTCTGAAACTGGGTATGAAGCGCGAACACATGTTGCAGCAGAAAGTGGAAAAAGAAGGGGCGGATCAGCCGTCA
ATTCTGCCTTAA

Upstream 100 bases:

>100_bases
GCGACGTCGATGTTTACCGCGATTGTCGGTACGCGTGCCATCGTAAACCTGCTATATGGCGGCAAGCGCGTCAAGAAGCT
GTCAATCTGAGGAGTGCGAT

Downstream 100 bases:

>100_bases
TCAAGTTTCAGCTGATGTTGAAAATCCCGGTCAGAAGATCGGGATTTTTTTTGATGTAAGGTGATTGCGAAAATCCCCGC
ATCTTGGGAAACTGCGCGTA

Product: preprotein translocase subunit SecF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MAQEYTVEQLNHGRKVYDFMRWDYWAFGISGLLLIAAIVIMGVRGFNWGLDFTGGTVIEITLEKPAEIDVMRDALQKAGF
EEPMLQNFGSSHDIMVRMPPAEGETGGQVLGSQVLKVINESTNQNAAVKRIEFVGPSVGADLAQTGAMALMAALLSILVY
VGFRFEWRLAAGVVIALAHDVIITLGILSLFHIEIDLTIVASLMSVIGYSLNDSIVVSDRIRENFRKIRRGTPYEIFNVS
LTQTLHRTLITSGTTLMVILMLYLFGGPVLEGFSLTMLIGVSIGTASSIYVASALALKLGMKREHMLQQKVEKEGADQPS
ILP

Sequences:

>Translated_323_residues
MAQEYTVEQLNHGRKVYDFMRWDYWAFGISGLLLIAAIVIMGVRGFNWGLDFTGGTVIEITLEKPAEIDVMRDALQKAGF
EEPMLQNFGSSHDIMVRMPPAEGETGGQVLGSQVLKVINESTNQNAAVKRIEFVGPSVGADLAQTGAMALMAALLSILVY
VGFRFEWRLAAGVVIALAHDVIITLGILSLFHIEIDLTIVASLMSVIGYSLNDSIVVSDRIRENFRKIRRGTPYEIFNVS
LTQTLHRTLITSGTTLMVILMLYLFGGPVLEGFSLTMLIGVSIGTASSIYVASALALKLGMKREHMLQQKVEKEGADQPS
ILP
>Mature_322_residues
AQEYTVEQLNHGRKVYDFMRWDYWAFGISGLLLIAAIVIMGVRGFNWGLDFTGGTVIEITLEKPAEIDVMRDALQKAGFE
EPMLQNFGSSHDIMVRMPPAEGETGGQVLGSQVLKVINESTNQNAAVKRIEFVGPSVGADLAQTGAMALMAALLSILVYV
GFRFEWRLAAGVVIALAHDVIITLGILSLFHIEIDLTIVASLMSVIGYSLNDSIVVSDRIRENFRKIRRGTPYEIFNVSL
TQTLHRTLITSGTTLMVILMLYLFGGPVLEGFSLTMLIGVSIGTASSIYVASALALKLGMKREHMLQQKVEKEGADQPSI
LP

Specific function: Involved in protein export

COG id: COG0341

COG function: function code U; Preprotein translocase subunit SecF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secD/secF family. SecF subfamily

Homologues:

Organism=Escherichia coli, GI1786610, Length=323, Percent_Identity=100, Blast_Score=653, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SECF_ECO57 (P0AG95)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   D90686
- PIR:   H85536
- RefSeq:   NP_286148.1
- RefSeq:   NP_308487.1
- ProteinModelPortal:   P0AG95
- EnsemblBacteria:   EBESCT00000028284
- EnsemblBacteria:   EBESCT00000057659
- GeneID:   914562
- GeneID:   957364
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z0508
- KEGG:   ecs:ECs0460
- GeneTree:   EBGT00050000009087
- HOGENOM:   HBG465293
- OMA:   MVRMPPV
- ProtClustDB:   PRK13022
- BioCyc:   ECOL83334:ECS0460-MONOMER
- InterPro:   IPR022813
- InterPro:   IPR022646
- InterPro:   IPR022645
- InterPro:   IPR005665
- PRINTS:   PR01755
- TIGRFAMs:   TIGR00916
- TIGRFAMs:   TIGR00966

Pfam domain/function: PF07549 Sec_GG; PF02355 SecD_SecF

EC number: NA

Molecular weight: Translated: 35383; Mature: 35252

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1eeefaec)-; HASH(0x1d8ed010)-; HASH(0x1edab75c)-; HASH(0x1d8b8030)-; HASH(0x1d96f798)-; HASH(0x1e2d3cb4)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQEYTVEQLNHGRKVYDFMRWDYWAFGISGLLLIAAIVIMGVRGFNWGLDFTGGTVIEI
CCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEE
TLEKPAEIDVMRDALQKAGFEEPMLQNFGSSHDIMVRMPPAEGETGGQVLGSQVLKVINE
EECCCCHHHHHHHHHHHCCCCCHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHC
STNQNAAVKRIEFVGPSVGADLAQTGAMALMAALLSILVYVGFRFEWRLAAGVVIALAHD
CCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHH
VIITLGILSLFHIEIDLTIVASLMSVIGYSLNDSIVVSDRIRENFRKIRRGTPYEIFNVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHCCCCCEEEEHH
LTQTLHRTLITSGTTLMVILMLYLFGGPVLEGFSLTMLIGVSIGTASSIYVASALALKLG
HHHHHHHHHHCCCHHHHHHHHHHHHCCCHHCCCCEEHEEEEECCCCHHHHHHHHHHHHHC
MKREHMLQQKVEKEGADQPSILP
CCHHHHHHHHHHHCCCCCCCCCH
>Mature Secondary Structure 
AQEYTVEQLNHGRKVYDFMRWDYWAFGISGLLLIAAIVIMGVRGFNWGLDFTGGTVIEI
CCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEE
TLEKPAEIDVMRDALQKAGFEEPMLQNFGSSHDIMVRMPPAEGETGGQVLGSQVLKVINE
EECCCCHHHHHHHHHHHCCCCCHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHC
STNQNAAVKRIEFVGPSVGADLAQTGAMALMAALLSILVYVGFRFEWRLAAGVVIALAHD
CCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHH
VIITLGILSLFHIEIDLTIVASLMSVIGYSLNDSIVVSDRIRENFRKIRRGTPYEIFNVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHCCCCCEEEEHH
LTQTLHRTLITSGTTLMVILMLYLFGGPVLEGFSLTMLIGVSIGTASSIYVASALALKLG
HHHHHHHHHHCCCHHHHHHHHHHHHCCCHHCCCCEEHEEEEECCCCHHHHHHHHHHHHHC
MKREHMLQQKVEKEGADQPSILP
CCHHHHHHHHHHHCCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796