Click here to switch to the map view.

The map label for this gene is yccK [H]

Identifier: 218549988

GI number: 218549988

Start: 2751606

End: 2752595

Strand: Direct

Name: yccK [H]

Synonym: EFER_2673

Alternate gene names: 218549988

Gene position: 2751606-2752595 (Clockwise)

Preceding gene: 218549987

Following gene: 218549990

Centisome position: 59.96

GC content: 50.81

Gene sequence:

>990_bases
ATGCAAAAACGTTATCTGGGTAATTCCGGACTCGAAGTTTCCGCTCTTGGACTCGGTTGCATGGGCTTAAGCCACGGCTA
CGGCCCGGCGACCGATACCCGTCAGGCTATCGAACTTATTCGTGCTGCGGTTGAACGTGGCGTCACCTTCTTCGATACCG
CCGAAGTGTATGGTCCGTATCTGAATGAAGAAGTGGTCGGTGAAGCCTTAAAACCATTTCGTAACCGCGTGGTGATTGCC
ACTAAATTCGGTTTTACCTTCGGCGATGATAATAAGCAGCAGATTTTAAACAGCCGTCCGGAACATATCCGTGAAGCCGT
TGAAGGATCATTACGTCGTCTGAAGACAGATGTTATTGACCTGCTGTACCAACACCGTGTTGATCCGGATGTTCCTATCG
AAGATGTTGCAGGAACGGTGAAAGATCTAATCGCAGAAGGTAAGGTCAAACATTTCGGCCTGTCTGAAGCGGGAGCGCAA
ACCATTCGTCGCGCGCATGCTGTACAACCTGTCACCGCCCTGCAAAGCGAATATTCCATGTGGTGGCGTGAGCCTGAGCA
GGAAATTCTGCCGTTGCTTGAGGAACTGGGGATTGGTTTTGTCCCCTTCAGCCCACTAGGTAAAGGTTTCCTGACAGGGG
CGATTAAGCCGGGAACCACTTTCGGCAAAGATGATTACCGTAGCACCGTACCGCGTTTTGCTGCACAAGCCATTGAAGCC
AATGAAAAACTGGTCACCTTGTTAGGTGAACTGGCCGCAGAGAAAGGGGTTACGTCTGCGCAAATCGCACTGGCATGGTT
GTTAGCACAAAAGCCGTGGATTGTTCCCATCCCGGGCACCACTAAACTGCACCGGCTGGAGGAAAATCTGACCGCTGTCG
ACATCGTTCTTTCGCAGAAAGATACGCAGCAGATAACCCAGTCACTGGAAACAATTAAAATAGTCGGTGAACGTTACTCG
CCTGAGCACCAGGCTCGCATAGATCGTTAA

Upstream 100 bases:

>100_bases
CAACCAGCGCGTTCTTCTCTCACCGCGACCCAGCGATGGTGGAATGGCTGACTGGCCGCAAACTTGATGTTTAAGCCGTA
ATACAAGAGGTATTCATTCA

Downstream 100 bases:

>100_bases
TATCCACACGGGTCAGCAGCAAAATGCGGACCCGTTATTCCGAGTAGCGAAGTGCATCGATCAACAGCGCAAAAGCTGGC
GGATGCTGCTTACGGCTGGG

Product: aldo-keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MQKRYLGNSGLEVSALGLGCMGLSHGYGPATDTRQAIELIRAAVERGVTFFDTAEVYGPYLNEEVVGEALKPFRNRVVIA
TKFGFTFGDDNKQQILNSRPEHIREAVEGSLRRLKTDVIDLLYQHRVDPDVPIEDVAGTVKDLIAEGKVKHFGLSEAGAQ
TIRRAHAVQPVTALQSEYSMWWREPEQEILPLLEELGIGFVPFSPLGKGFLTGAIKPGTTFGKDDYRSTVPRFAAQAIEA
NEKLVTLLGELAAEKGVTSAQIALAWLLAQKPWIVPIPGTTKLHRLEENLTAVDIVLSQKDTQQITQSLETIKIVGERYS
PEHQARIDR

Sequences:

>Translated_329_residues
MQKRYLGNSGLEVSALGLGCMGLSHGYGPATDTRQAIELIRAAVERGVTFFDTAEVYGPYLNEEVVGEALKPFRNRVVIA
TKFGFTFGDDNKQQILNSRPEHIREAVEGSLRRLKTDVIDLLYQHRVDPDVPIEDVAGTVKDLIAEGKVKHFGLSEAGAQ
TIRRAHAVQPVTALQSEYSMWWREPEQEILPLLEELGIGFVPFSPLGKGFLTGAIKPGTTFGKDDYRSTVPRFAAQAIEA
NEKLVTLLGELAAEKGVTSAQIALAWLLAQKPWIVPIPGTTKLHRLEENLTAVDIVLSQKDTQQITQSLETIKIVGERYS
PEHQARIDR
>Mature_329_residues
MQKRYLGNSGLEVSALGLGCMGLSHGYGPATDTRQAIELIRAAVERGVTFFDTAEVYGPYLNEEVVGEALKPFRNRVVIA
TKFGFTFGDDNKQQILNSRPEHIREAVEGSLRRLKTDVIDLLYQHRVDPDVPIEDVAGTVKDLIAEGKVKHFGLSEAGAQ
TIRRAHAVQPVTALQSEYSMWWREPEQEILPLLEELGIGFVPFSPLGKGFLTGAIKPGTTFGKDDYRSTVPRFAAQAIEA
NEKLVTLLGELAAEKGVTSAQIALAWLLAQKPWIVPIPGTTKLHRLEENLTAVDIVLSQKDTQQITQSLETIKIVGERYS
PEHQARIDR

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=326, Percent_Identity=29.1411042944785, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI27436971, Length=321, Percent_Identity=30.5295950155763, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI27436962, Length=326, Percent_Identity=29.1411042944785, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI27436966, Length=326, Percent_Identity=29.1411042944785, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI27436969, Length=310, Percent_Identity=30.3225806451613, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI4504825, Length=307, Percent_Identity=30.2931596091205, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI223718702, Length=215, Percent_Identity=31.1627906976744, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI41152114, Length=205, Percent_Identity=32.1951219512195, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI41327764, Length=279, Percent_Identity=29.7491039426523, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI87081735, Length=335, Percent_Identity=33.4328358208955, Blast_Score=161, Evalue=4e-41,
Organism=Escherichia coli, GI1789375, Length=333, Percent_Identity=28.5285285285285, Blast_Score=131, Evalue=6e-32,
Organism=Escherichia coli, GI1788070, Length=331, Percent_Identity=31.7220543806647, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1787674, Length=297, Percent_Identity=30.3030303030303, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1789199, Length=337, Percent_Identity=27.299703264095, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1788081, Length=312, Percent_Identity=23.7179487179487, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI48994888, Length=286, Percent_Identity=27.6223776223776, Blast_Score=80, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6325169, Length=354, Percent_Identity=27.9661016949153, Blast_Score=132, Evalue=6e-32,
Organism=Saccharomyces cerevisiae, GI6323998, Length=308, Percent_Identity=27.9220779220779, Blast_Score=107, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6319958, Length=283, Percent_Identity=27.5618374558304, Blast_Score=103, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6325384, Length=337, Percent_Identity=27.299703264095, Blast_Score=102, Evalue=8e-23,
Organism=Saccharomyces cerevisiae, GI6319951, Length=314, Percent_Identity=27.0700636942675, Blast_Score=100, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6322615, Length=243, Percent_Identity=26.7489711934156, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6321052, Length=151, Percent_Identity=30.4635761589404, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24640980, Length=327, Percent_Identity=25.3822629969419, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI45549126, Length=327, Percent_Identity=25.3822629969419, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24646155, Length=320, Percent_Identity=26.875, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24646159, Length=223, Percent_Identity=26.9058295964126, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36368; Mature: 36368

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKRYLGNSGLEVSALGLGCMGLSHGYGPATDTRQAIELIRAAVERGVTFFDTAEVYGPY
CCCCCCCCCCCEEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCEEEEHHHHHCCC
LNEEVVGEALKPFRNRVVIATKFGFTFGDDNKQQILNSRPEHIREAVEGSLRRLKTDVID
CCHHHHHHHHHHHHCCEEEEEECCCEECCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
LLYQHRVDPDVPIEDVAGTVKDLIAEGKVKHFGLSEAGAQTIRRAHAVQPVTALQSEYSM
HHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHH
WWREPEQEILPLLEELGIGFVPFSPLGKGFLTGAIKPGTTFGKDDYRSTVPRFAAQAIEA
HHCCCHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHC
NEKLVTLLGELAAEKGVTSAQIALAWLLAQKPWIVPIPGTTKLHRLEENLTAVDIVLSQK
CHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEECCCCHHHHHHHHCCCEEEHHHCCH
DTQQITQSLETIKIVGERYSPEHQARIDR
HHHHHHHHHHHHHHHHCCCCCHHHHCCCC
>Mature Secondary Structure
MQKRYLGNSGLEVSALGLGCMGLSHGYGPATDTRQAIELIRAAVERGVTFFDTAEVYGPY
CCCCCCCCCCCEEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCEEEEHHHHHCCC
LNEEVVGEALKPFRNRVVIATKFGFTFGDDNKQQILNSRPEHIREAVEGSLRRLKTDVID
CCHHHHHHHHHHHHCCEEEEEECCCEECCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
LLYQHRVDPDVPIEDVAGTVKDLIAEGKVKHFGLSEAGAQTIRRAHAVQPVTALQSEYSM
HHHHHCCCCCCCHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHH
WWREPEQEILPLLEELGIGFVPFSPLGKGFLTGAIKPGTTFGKDDYRSTVPRFAAQAIEA
HHCCCHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHC
NEKLVTLLGELAAEKGVTSAQIALAWLLAQKPWIVPIPGTTKLHRLEENLTAVDIVLSQK
CHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEECCCCHHHHHHHHCCCEEEHHHCCH
DTQQITQSLETIKIVGERYSPEHQARIDR
HHHHHHHHHHHHHHHHCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]