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The map label for this gene is dppB [C]

Identifier: 218549130

GI number: 218549130

Start: 1832647

End: 1833636

Strand: Reverse

Name: dppB [C]

Synonym: EFER_1782

Alternate gene names: 218549130

Gene position: 1833636-1832647 (Counterclockwise)

Preceding gene: 218549131

Following gene: 218549129

Centisome position: 39.96

GC content: 51.31

Gene sequence:

>990_bases
ATGGACTTGTCGTTAATGATGCGTATTGCCCATCATTTGCTGCGGTTGGTAACTCTGCTAATGCTGGTGGCGGCAGGTAC
ATTTATGCTGCTAAGTTTCTCGCCCGTTGACCCCATCCGTGCCTATATCGGTAATGATCTGCTGCATGTGCCACCAGAAC
AATATGCCCGTATTGCCGCACGTTGGGGGCTTGATCAACCATTATGGCAGCGTTTTGCTCACTGGTTTTTCCGTCTGTTA
CAGGGAGATTTAGGTTATTCGATGCTGTATAACGCCCCGGTTGCGAAAGTGATCGGCGAGCGTTTTGCTACCTCCTTTGC
CTTGTTGGCCGGCGCATGGCTGTTGTCGGGCTTGCTGGGAATTTCAGCGGGATTTCTGGCCGGGCGCTATTTGCACCGCT
GGCCCGATAAACTGATCTGTCGAGCGAGTTATCTCCTGTCATCATTACCTACATTCTGGATAGGGCTGCTACTGCTGGCC
TTATTTGCCGTTCGCTGGCCCGTCTTGCCGGTTTGCTGTGCCTGGGAACCTGGTAACAGTGGCGATGTCGCTACTGTTAC
CGAACGAATACGCCATTTGATCTTACCTGTATCTGCTCTCAGCCTTTTGGGTATGGGGCAGATCGCACTACATACTCGTG
AAAAAATAGCCAGTGTAATGGGCAGTGAATTTGTCCGCTTTGCCCGTGCACAGGGTGATGCTGGCTGGTCACTATTGGGT
CATCATGTGCTGCGTCATGCCATTACGCCTGCTCTGTGTTTGCAATTTGCTTCTTTGGGGGAGTTGCTTGGCGGAGCGTT
GTTGGCTGAAAAGGTTTTTGCTTATCCTGGCCTTGGTCAGGCAACTATCGATGCCGGATTGCGTGGTGATGTGCCGTTGT
TATTGGGCATTGTACTCTTTAGCACGTTGCTGGTTTTTGTGGGGAATAGTCTGTCTGCATGGCTGGTGAATCGGCTGAAT
TATGCGTTGGAGCGGCCAGATGCTTTATAA

Upstream 100 bases:

>100_bases
TTCAACACACTTATCTTGCTAATCCATGTATCGACCTGGGTAAAGGCGCACCGGAAATTCATGGTAGCTGGTCACTGCTA
AATAACTTGTCTGACTGGAA

Downstream 100 bases:

>100_bases
CCCAGCTCCAGTTCTCCTTCGGCTCTTCGTATCTGCCTCTTTGCTGCTCATCATAACCTGTTGTGGCGTGCTGGCATTAC
AGGACCCCCTGGCAGTTAAT

Product: inner membrane nickel transport protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MDLSLMMRIAHHLLRLVTLLMLVAAGTFMLLSFSPVDPIRAYIGNDLLHVPPEQYARIAARWGLDQPLWQRFAHWFFRLL
QGDLGYSMLYNAPVAKVIGERFATSFALLAGAWLLSGLLGISAGFLAGRYLHRWPDKLICRASYLLSSLPTFWIGLLLLA
LFAVRWPVLPVCCAWEPGNSGDVATVTERIRHLILPVSALSLLGMGQIALHTREKIASVMGSEFVRFARAQGDAGWSLLG
HHVLRHAITPALCLQFASLGELLGGALLAEKVFAYPGLGQATIDAGLRGDVPLLLGIVLFSTLLVFVGNSLSAWLVNRLN
YALERPDAL

Sequences:

>Translated_329_residues
MDLSLMMRIAHHLLRLVTLLMLVAAGTFMLLSFSPVDPIRAYIGNDLLHVPPEQYARIAARWGLDQPLWQRFAHWFFRLL
QGDLGYSMLYNAPVAKVIGERFATSFALLAGAWLLSGLLGISAGFLAGRYLHRWPDKLICRASYLLSSLPTFWIGLLLLA
LFAVRWPVLPVCCAWEPGNSGDVATVTERIRHLILPVSALSLLGMGQIALHTREKIASVMGSEFVRFARAQGDAGWSLLG
HHVLRHAITPALCLQFASLGELLGGALLAEKVFAYPGLGQATIDAGLRGDVPLLLGIVLFSTLLVFVGNSLSAWLVNRLN
YALERPDAL
>Mature_329_residues
MDLSLMMRIAHHLLRLVTLLMLVAAGTFMLLSFSPVDPIRAYIGNDLLHVPPEQYARIAARWGLDQPLWQRFAHWFFRLL
QGDLGYSMLYNAPVAKVIGERFATSFALLAGAWLLSGLLGISAGFLAGRYLHRWPDKLICRASYLLSSLPTFWIGLLLLA
LFAVRWPVLPVCCAWEPGNSGDVATVTERIRHLILPVSALSLLGMGQIALHTREKIASVMGSEFVRFARAQGDAGWSLLG
HHVLRHAITPALCLQFASLGELLGGALLAEKVFAYPGLGQATIDAGLRGDVPLLLGIVLFSTLLVFVGNSLSAWLVNRLN
YALERPDAL

Specific function: Probably part of an ABC transporter complex that could be involved in peptide import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=312, Percent_Identity=29.8076923076923, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1787053, Length=305, Percent_Identity=30.8196721311475, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1789888, Length=316, Percent_Identity=27.2151898734177, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1787761, Length=297, Percent_Identity=31.3131313131313, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1787497, Length=299, Percent_Identity=28.4280936454849, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1787550, Length=266, Percent_Identity=29.3233082706767, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1788504, Length=288, Percent_Identity=26.0416666666667, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 36101; Mature: 36101

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLSLMMRIAHHLLRLVTLLMLVAAGTFMLLSFSPVDPIRAYIGNDLLHVPPEQYARIAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEECCHHHHHHHHH
RWGLDQPLWQRFAHWFFRLLQGDLGYSMLYNAPVAKVIGERFATSFALLAGAWLLSGLLG
HCCCCHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISAGFLAGRYLHRWPDKLICRASYLLSSLPTFWIGLLLLALFAVRWPVLPVCCAWEPGNS
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEECCCCCCC
GDVATVTERIRHLILPVSALSLLGMGQIALHTREKIASVMGSEFVRFARAQGDAGWSLLG
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
HHVLRHAITPALCLQFASLGELLGGALLAEKVFAYPGLGQATIDAGLRGDVPLLLGIVLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHH
STLLVFVGNSLSAWLVNRLNYALERPDAL
HHHHHHHCCCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MDLSLMMRIAHHLLRLVTLLMLVAAGTFMLLSFSPVDPIRAYIGNDLLHVPPEQYARIAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEECCHHHHHHHHH
RWGLDQPLWQRFAHWFFRLLQGDLGYSMLYNAPVAKVIGERFATSFALLAGAWLLSGLLG
HCCCCHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISAGFLAGRYLHRWPDKLICRASYLLSSLPTFWIGLLLLALFAVRWPVLPVCCAWEPGNS
HHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEECCCCCCC
GDVATVTERIRHLILPVSALSLLGMGQIALHTREKIASVMGSEFVRFARAQGDAGWSLLG
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
HHVLRHAITPALCLQFASLGELLGGALLAEKVFAYPGLGQATIDAGLRGDVPLLLGIVLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHH
STLLVFVGNSLSAWLVNRLNYALERPDAL
HHHHHHHCCCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]