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The map label for this gene is dsbB [H]

Identifier: 218549118

GI number: 218549118

Start: 1821996

End: 1822526

Strand: Direct

Name: dsbB [H]

Synonym: EFER_1770

Alternate gene names: 218549118

Gene position: 1821996-1822526 (Clockwise)

Preceding gene: 218549117

Following gene: 218549124

Centisome position: 39.71

GC content: 48.4

Gene sequence:

>531_bases
ATGTTGCGATTTTTAAACCAGTGCTCACGAGGACGCGGTGCGTGGTTGTTGATGGCCTTTACCGCCCTCGCCCTTGAATT
GGTAGCGCTATGGTTCCAGCACGTTATGCTGCTAAAACCTTGTGTGCTATGCATTTACGAACGTTGTGCGCTTTTTGGCA
TTCTTGGGGCCGCATTAATTGGTGCCATTGCCCCTAAAACCCCGTTGCGATATGTCGCAATCATTATCTGGCTGTATAGT
GCCTGGCGCGGTGTGCAGTTGACCTATGAACATACGATGCTGCAGCTTTACCCTTCACCCTTTGTAACCTGCGACTTTTT
CGTTCGTTTCCCGAGTTGGTTGCCCCTGGATAAATGGATCCCACAAGTGTTTGTCGCTTCCGGGGATTGTGCAGAACGGC
AGTGGGAATTTTTAGGACTGGAAATGCCACAATGGTTGCTGGGTATTTTTGTGGCCTATCTTATTGTTGCTATCCTGGTA
GCGATTTCTCAGCCATTCAAAGCGAAAAAACGTGATCTGTTTGGTCGTTAA

Upstream 100 bases:

>100_bases
GATTAATTACCTAATTACACTTTATTTTATTTCGCGCTAGTGGCGTGACAAATGAATTGGTTTACACTGCGTGCTCTATG
CATGTTGCAGGGAAATTATT

Downstream 100 bases:

>100_bases
TCACTGACCGCTTTTTGCTAAAGATCGAAATAAGGGGGCACAATGGCCCCCTTTTCATTATTGATTATTGCTGTGGATTT
TTCGGTAACTCCGAAACCCA

Product: disulfide bond formation protein B

Products: NA

Alternate protein names: Disulfide oxidoreductase [H]

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MLRFLNQCSRGRGAWLLMAFTALALELVALWFQHVMLLKPCVLCIYERCALFGILGAALIGAIAPKTPLRYVAIIIWLYS
AWRGVQLTYEHTMLQLYPSPFVTCDFFVRFPSWLPLDKWIPQVFVASGDCAERQWEFLGLEMPQWLLGIFVAYLIVAILV
AISQPFKAKKRDLFGR

Sequences:

>Translated_176_residues
MLRFLNQCSRGRGAWLLMAFTALALELVALWFQHVMLLKPCVLCIYERCALFGILGAALIGAIAPKTPLRYVAIIIWLYS
AWRGVQLTYEHTMLQLYPSPFVTCDFFVRFPSWLPLDKWIPQVFVASGDCAERQWEFLGLEMPQWLLGIFVAYLIVAILV
AISQPFKAKKRDLFGR
>Mature_176_residues
MLRFLNQCSRGRGAWLLMAFTALALELVALWFQHVMLLKPCVLCIYERCALFGILGAALIGAIAPKTPLRYVAIIIWLYS
AWRGVQLTYEHTMLQLYPSPFVTCDFFVRFPSWLPLDKWIPQVFVASGDCAERQWEFLGLEMPQWLLGIFVAYLIVAILV
AISQPFKAKKRDLFGR

Specific function: Required for disulfide bond formation in some periplasmic proteins such as PhoA or OmpA. Acts by oxidizing the DsbA protein [H]

COG id: COG1495

COG function: function code O; Disulfide bond formation protein DsbB

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbB family [H]

Homologues:

Organism=Escherichia coli, GI1787433, Length=176, Percent_Identity=92.0454545454545, Blast_Score=338, Evalue=1e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003752
- InterPro:   IPR022920 [H]

Pfam domain/function: PF02600 DsbB [H]

EC number: NA

Molecular weight: Translated: 20220; Mature: 20220

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRFLNQCSRGRGAWLLMAFTALALELVALWFQHVMLLKPCVLCIYERCALFGILGAALI
CCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAIAPKTPLRYVAIIIWLYSAWRGVQLTYEHTMLQLYPSPFVTCDFFVRFPSWLPLDKWI
HHHCCCCHHHHHHHHHHHHHHHCCCEEHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHH
PQVFVASGDCAERQWEFLGLEMPQWLLGIFVAYLIVAILVAISQPFKAKKRDLFGR
HHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCC
>Mature Secondary Structure
MLRFLNQCSRGRGAWLLMAFTALALELVALWFQHVMLLKPCVLCIYERCALFGILGAALI
CCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAIAPKTPLRYVAIIIWLYSAWRGVQLTYEHTMLQLYPSPFVTCDFFVRFPSWLPLDKWI
HHHCCCCHHHHHHHHHHHHHHHCCCEEHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHH
PQVFVASGDCAERQWEFLGLEMPQWLLGIFVAYLIVAILVAISQPFKAKKRDLFGR
HHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]