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The map label for this gene is minC [H]

Identifier: 218549124

GI number: 218549124

Start: 1828277

End: 1828999

Strand: Direct

Name: minC [H]

Synonym: EFER_1776

Alternate gene names: 218549124

Gene position: 1828277-1828999 (Clockwise)

Preceding gene: 218549118

Following gene: 218549125

Centisome position: 39.84

GC content: 48.27

Gene sequence:

>723_bases
TTGAGTAAGGCCAGGATGTCAAACACGCCAATCGAGCTTAAAGGCAGCAGCTTCACCTTATCAGTGGTTCATTTACATGA
GGCTGAACCAGAGGTTATTCGTCAGGCGTTGGAAGACAAAATCGCGCAAGCTCCTGCTTTTTTACGACATGCACCAGTGG
TTATCAATGTCGGTGACCTTGAAAACCCGGTTAACTGGTCTGCGCTACAAAAAGCAGTGTCATCCACAGGTTTGCGCATT
ATTGGCGTCAGCGGCTGTAAAGATGCCTCACTGAAAGCTGAAATTGATGAGATGGGGCTTCCCTTACTGACTGAAGGTAA
AGAGAAAGTTGCGCGTTCCCGCCCTGCTGAGGTTATTACCCCAGCCACTCCGGTGCAAAACGCTAACCCCATCACAAAAA
CGCGATTAATAGATGTTCCCGTACGTTCCGGTCAGCGAATTTATGCTCCACAATGTGATCTAATAGTGACTAATCACGTC
AGTGCTGGTGCAGAACTCATCGCCGATGGCAATATTCATGTGTATGGCATGATGCGTGGTCGTGCGCTTGCGGGAGCAGC
GGGTGATCGTGAAGCACAAATATTTTGTACCAACCTGACGGCAGAACTAGTATCTATTGCAGGTGTTTACTGGCTGAGTG
ATAAAATCCCGGCAGAATTTTATGGCAAAGCGGCACGTCTGCGGCTGGCAGATAACGCTTTGTCAGTTCAACCGTTAAAT
TGA

Upstream 100 bases:

>100_bases
CTGAATTAATGGGATGGTGACTTGCCTGAATATAATAGTGACTATAACATGCCTTCTGGACTTCGGAATATCTCCCCATA
CCGGGAAGATAATTAGCTAA

Downstream 100 bases:

>100_bases
TCCCTTTTTAACAAGGAATTTCTATGGCACGCATTATTGTTGTTACTTCGGGTAAAGGTGGCGTCGGCAAAACCACCTCC
AGCGCGGCCATCGCTACTGG

Product: septum formation inhibitor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MSKARMSNTPIELKGSSFTLSVVHLHEAEPEVIRQALEDKIAQAPAFLRHAPVVINVGDLENPVNWSALQKAVSSTGLRI
IGVSGCKDASLKAEIDEMGLPLLTEGKEKVARSRPAEVITPATPVQNANPITKTRLIDVPVRSGQRIYAPQCDLIVTNHV
SAGAELIADGNIHVYGMMRGRALAGAAGDREAQIFCTNLTAELVSIAGVYWLSDKIPAEFYGKAARLRLADNALSVQPLN

Sequences:

>Translated_240_residues
MSKARMSNTPIELKGSSFTLSVVHLHEAEPEVIRQALEDKIAQAPAFLRHAPVVINVGDLENPVNWSALQKAVSSTGLRI
IGVSGCKDASLKAEIDEMGLPLLTEGKEKVARSRPAEVITPATPVQNANPITKTRLIDVPVRSGQRIYAPQCDLIVTNHV
SAGAELIADGNIHVYGMMRGRALAGAAGDREAQIFCTNLTAELVSIAGVYWLSDKIPAEFYGKAARLRLADNALSVQPLN
>Mature_239_residues
SKARMSNTPIELKGSSFTLSVVHLHEAEPEVIRQALEDKIAQAPAFLRHAPVVINVGDLENPVNWSALQKAVSSTGLRII
GVSGCKDASLKAEIDEMGLPLLTEGKEKVARSRPAEVITPATPVQNANPITKTRLIDVPVRSGQRIYAPQCDLIVTNHVS
AGAELIADGNIHVYGMMRGRALAGAAGDREAQIFCTNLTAELVSIAGVYWLSDKIPAEFYGKAARLRLADNALSVQPLN

Specific function: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize ftsZ filaments that have formed before they mature into polar Z rings. Prevents ftsZ polymerization [H]

COG id: COG0850

COG function: function code D; Septum formation inhibitor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the minC family [H]

Homologues:

Organism=Escherichia coli, GI1787424, Length=235, Percent_Identity=82.9787234042553, Blast_Score=408, Evalue=1e-115,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016098
- InterPro:   IPR013033
- InterPro:   IPR007874
- InterPro:   IPR005526 [H]

Pfam domain/function: PF03775 MinC_C; PF05209 MinC_N [H]

EC number: NA

Molecular weight: Translated: 25738; Mature: 25607

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKARMSNTPIELKGSSFTLSVVHLHEAEPEVIRQALEDKIAQAPAFLRHAPVVINVGDL
CCCCCCCCCCEEEECCEEEEEEEEEECCCHHHHHHHHHHHHHHCCHHHHCCCEEEECCCC
ENPVNWSALQKAVSSTGLRIIGVSGCKDASLKAEIDEMGLPLLTEGKEKVARSRPAEVIT
CCCCCHHHHHHHHHHCCEEEEEECCCCCCCCEEEHHHCCCCEEECCHHHHHHCCCCCEEC
PATPVQNANPITKTRLIDVPVRSGQRIYAPQCDLIVTNHVSAGAELIADGNIHVYGMMRG
CCCCCCCCCCCCEEEEEEEECCCCCEEECCCCCEEEECCCCCCCEEEECCCEEEEEEECC
RALAGAAGDREAQIFCTNLTAELVSIAGVYWLSDKIPAEFYGKAARLRLADNALSVQPLN
CEEECCCCCCCEEEEEECHHHHHHHHHHHEEECCCCCHHHCCCEEEEEEECCCEEEEECC
>Mature Secondary Structure 
SKARMSNTPIELKGSSFTLSVVHLHEAEPEVIRQALEDKIAQAPAFLRHAPVVINVGDL
CCCCCCCCCEEEECCEEEEEEEEEECCCHHHHHHHHHHHHHHCCHHHHCCCEEEECCCC
ENPVNWSALQKAVSSTGLRIIGVSGCKDASLKAEIDEMGLPLLTEGKEKVARSRPAEVIT
CCCCCHHHHHHHHHHCCEEEEEECCCCCCCCEEEHHHCCCCEEECCHHHHHHCCCCCEEC
PATPVQNANPITKTRLIDVPVRSGQRIYAPQCDLIVTNHVSAGAELIADGNIHVYGMMRG
CCCCCCCCCCCCEEEEEEEECCCCCEEECCCCCEEEECCCCCCCEEEECCCEEEEEEECC
RALAGAAGDREAQIFCTNLTAELVSIAGVYWLSDKIPAEFYGKAARLRLADNALSVQPLN
CEEECCCCCCCEEEEEECHHHHHHHHHHHEEECCCCCHHHCCCEEEEEEECCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA