Click here to switch to the map view.

The map label for this gene is yeeJ [C]

Identifier: 218548924

GI number: 218548924

Start: 1602900

End: 1604918

Strand: Reverse

Name: yeeJ [C]

Synonym: EFER_1570

Alternate gene names: 218548924

Gene position: 1604918-1602900 (Counterclockwise)

Preceding gene: 218548925

Following gene: 218548922

Centisome position: 34.98

GC content: 47.65

Gene sequence:

>2019_bases
GTGAAATTAACACCTACACCTTTGGCTCGCTGGTTGGCCTGGGTATTAGTCGGTACACAGCTGCTGACCCCGGCGGCACT
TGCCCAGGCAATGCTACCGGAAATCACTCGATCAGGTGCAGATAGCAGCGTCGATAAAACAGATCAACCCGAAGCAGAAT
GGCTGGCTTCACGCGCATCGTCCCTGGGTAGCTTGTTGCAAGAAGGTAATATTAGCGACTTCGCAAAAAATCAGATCCAG
GCGCTACCACAAACTATTGCTAACGATGGCATTACCAGCGGTATCAAACACTGGCTGCCCGAGGCGCAGTTTCGTGGGGG
GATCACCCTGGAAGACGCAAGCAAGTATCGTTCAGCAGAAGCAGACCTGCTGATTCCATTATATCAGTCCACTAGTTCGA
TCTTATTTGGACAGTTGGGCCTACGCGACCACGATAATAATAGTTTTAATGGCCGATTTTTCGTAAACACCGGTATTGGC
TGGCGTCAGGATGTCGGCGACTGGTTACTGGGTATCAACTCCTTCCTGGATGCTGATGTACGTTACGATCATTTACGGGG
AAGTCTGGGCGTTGAGTTATTTCGCGATAGTATGAGTCTGGCTGGCAACTGGTACTTTCCTCTCTCGGACTGGAAAGCTT
CGAAAGTGCAACCGCTTCATGATGAAAGACCGGCAACGGGTATTGATGTACGGCTCAAAGGTGCGTTACCGTCACTGCCC
TGGTTTGGAGCGGAACTGGCATTTGAACAATATTTTGGTGATAAAGTCGATATCCTCGGGAACGACTCACTGACTCGCGA
TCCTGCGGCGTTCACTGGTGCAATTACGTGGAAACCAGTACCTCTTGTTGAGATCAAGGCGGGGTACAAAGATGCCGGTA
GTAGTGGTTCACAAACAGAAGCGGGATTAAACCTGAATTACACCTTTGGTGTACCGCTGAGGGCACAGTTGGATCCTTCC
CAGGTTCGCCCAGCCAGTAACACGACCAACCGTACTGCCTTTGTTGATCGTAATTACAATATTGTTATGGAATATCGCGA
ACAGGCCAGTCGTATACGAGTATATGCCTCACCTGTAAACGGTCAGTCAGGTGACACCGTCACGTTAAGTGCAACTATAA
ACAGTCGTTATCCAGTTGAACGCATTGAGTGGACAGGTGACGCTGAACTTATTGGCGGATTACAACAACAGGGTAATGTC
AATAGTGGATTGCGATTACCTGATCTCTCTCTGGACGTCACTGAAAATAAAGAATATTCATTGTATTTAAAAGTTACGGA
CAGCCGGGGAAATTCGGTAACCTCTGAGCGCATCCCGGTTACAGTAAGTATTAATCCTGAAAGTTTCACACCTTATTTAA
ACGTACTTCATGATGAAGTTCGCCGTGAAGAGGGTAAATTTGTTATTCCTTCACCAACAGTCAACGATGACAATGGCAGT
ATCATAGAATGGCATTATGTTCGAGTACGCTCGAAAGACGAATGGAAAAGCTTAAAACCTGAAAACGTGGAATATAGTAC
TCATAGTCCCGGACTGTCGTTTAAATCTTTGGGGGGTGAAGAACGTGATGGACAATGGATCGAAAAAGTGCAACTCGTTG
TCAAAGATCCTACAGCACGTATGACACTAGCAGCGATGGAACTTAATATTTCAGCTACAGGCCCGGGGGGCACTCATCCG
GTAAATGGTACTATCCGTATGACCCCGGTGATGAATCTCACCGATAAAGTGAGCAGTGTTCAAATACTTTTCACTGCTGG
AACTGAAGAACTTAATGGCAGTACAAATGCACCCGTTGTTGGCAGCACATTGCAGGCAAAGACTACCTGTGACACTGACA
AAGATTGCTCTTCGCTATTTCGTTATCAATGGGAAATATCCCCGGATGGTAACAGATGGTACGACGTGCCCGGTGCTACA
GGGCAGTCGTGGCTTATGCCCGCAGTGATGGACGGGCACTCATTGCAAAACAAGCAGGTCCGCGTTCGGGTGGTATCAGA
AAATGTCCCTACACATTAA

Upstream 100 bases:

>100_bases
GCAGCATATGCAACTCAAAGTATGACGAGTATAGCAAAATTAAAATGAGCTCTTTTATAAGGGAAGGGCTCTTTCTGGTT
CTGTCATGGAGAGATAATCA

Downstream 100 bases:

>100_bases
ATAACTGGAGATACAGGAACTGATCGCACTCCTGCCACTTATTAATATTTGTGGTGGGAGATATACTCGTCATACTTCAA
GTTGCATGTGCTGCATATAC

Product: invasin-like protein; protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 672; Mature: 672

Protein sequence:

>672_residues
MKLTPTPLARWLAWVLVGTQLLTPAALAQAMLPEITRSGADSSVDKTDQPEAEWLASRASSLGSLLQEGNISDFAKNQIQ
ALPQTIANDGITSGIKHWLPEAQFRGGITLEDASKYRSAEADLLIPLYQSTSSILFGQLGLRDHDNNSFNGRFFVNTGIG
WRQDVGDWLLGINSFLDADVRYDHLRGSLGVELFRDSMSLAGNWYFPLSDWKASKVQPLHDERPATGIDVRLKGALPSLP
WFGAELAFEQYFGDKVDILGNDSLTRDPAAFTGAITWKPVPLVEIKAGYKDAGSSGSQTEAGLNLNYTFGVPLRAQLDPS
QVRPASNTTNRTAFVDRNYNIVMEYREQASRIRVYASPVNGQSGDTVTLSATINSRYPVERIEWTGDAELIGGLQQQGNV
NSGLRLPDLSLDVTENKEYSLYLKVTDSRGNSVTSERIPVTVSINPESFTPYLNVLHDEVRREEGKFVIPSPTVNDDNGS
IIEWHYVRVRSKDEWKSLKPENVEYSTHSPGLSFKSLGGEERDGQWIEKVQLVVKDPTARMTLAAMELNISATGPGGTHP
VNGTIRMTPVMNLTDKVSSVQILFTAGTEELNGSTNAPVVGSTLQAKTTCDTDKDCSSLFRYQWEISPDGNRWYDVPGAT
GQSWLMPAVMDGHSLQNKQVRVRVVSENVPTH

Sequences:

>Translated_672_residues
MKLTPTPLARWLAWVLVGTQLLTPAALAQAMLPEITRSGADSSVDKTDQPEAEWLASRASSLGSLLQEGNISDFAKNQIQ
ALPQTIANDGITSGIKHWLPEAQFRGGITLEDASKYRSAEADLLIPLYQSTSSILFGQLGLRDHDNNSFNGRFFVNTGIG
WRQDVGDWLLGINSFLDADVRYDHLRGSLGVELFRDSMSLAGNWYFPLSDWKASKVQPLHDERPATGIDVRLKGALPSLP
WFGAELAFEQYFGDKVDILGNDSLTRDPAAFTGAITWKPVPLVEIKAGYKDAGSSGSQTEAGLNLNYTFGVPLRAQLDPS
QVRPASNTTNRTAFVDRNYNIVMEYREQASRIRVYASPVNGQSGDTVTLSATINSRYPVERIEWTGDAELIGGLQQQGNV
NSGLRLPDLSLDVTENKEYSLYLKVTDSRGNSVTSERIPVTVSINPESFTPYLNVLHDEVRREEGKFVIPSPTVNDDNGS
IIEWHYVRVRSKDEWKSLKPENVEYSTHSPGLSFKSLGGEERDGQWIEKVQLVVKDPTARMTLAAMELNISATGPGGTHP
VNGTIRMTPVMNLTDKVSSVQILFTAGTEELNGSTNAPVVGSTLQAKTTCDTDKDCSSLFRYQWEISPDGNRWYDVPGAT
GQSWLMPAVMDGHSLQNKQVRVRVVSENVPTH
>Mature_672_residues
MKLTPTPLARWLAWVLVGTQLLTPAALAQAMLPEITRSGADSSVDKTDQPEAEWLASRASSLGSLLQEGNISDFAKNQIQ
ALPQTIANDGITSGIKHWLPEAQFRGGITLEDASKYRSAEADLLIPLYQSTSSILFGQLGLRDHDNNSFNGRFFVNTGIG
WRQDVGDWLLGINSFLDADVRYDHLRGSLGVELFRDSMSLAGNWYFPLSDWKASKVQPLHDERPATGIDVRLKGALPSLP
WFGAELAFEQYFGDKVDILGNDSLTRDPAAFTGAITWKPVPLVEIKAGYKDAGSSGSQTEAGLNLNYTFGVPLRAQLDPS
QVRPASNTTNRTAFVDRNYNIVMEYREQASRIRVYASPVNGQSGDTVTLSATINSRYPVERIEWTGDAELIGGLQQQGNV
NSGLRLPDLSLDVTENKEYSLYLKVTDSRGNSVTSERIPVTVSINPESFTPYLNVLHDEVRREEGKFVIPSPTVNDDNGS
IIEWHYVRVRSKDEWKSLKPENVEYSTHSPGLSFKSLGGEERDGQWIEKVQLVVKDPTARMTLAAMELNISATGPGGTHP
VNGTIRMTPVMNLTDKVSSVQILFTAGTEELNGSTNAPVVGSTLQAKTTCDTDKDCSSLFRYQWEISPDGNRWYDVPGAT
GQSWLMPAVMDGHSLQNKQVRVRVVSENVPTH

Specific function: Invasin is a protein that allows enteric bacteria to penetrate cultured mammalian cells. The entry of invasin in the cell is mediated by binding several beta-1 chain integrins [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell surface [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 Big-1 (bacterial Ig-like domain 1) domains [H]

Homologues:

Organism=Escherichia coli, GI145693153, Length=331, Percent_Identity=30.2114803625378, Blast_Score=162, Evalue=8e-41,
Organism=Escherichia coli, GI145693120, Length=381, Percent_Identity=28.0839895013123, Blast_Score=142, Evalue=6e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003344
- InterPro:   IPR016186
- InterPro:   IPR016187
- InterPro:   IPR003535
- InterPro:   IPR013117
- InterPro:   IPR008964
- InterPro:   IPR015217 [H]

Pfam domain/function: PF02369 Big_1; PF07979 Intimin_C; PF09134 Invasin_D3 [H]

EC number: NA

Molecular weight: Translated: 73999; Mature: 73999

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTPTPLARWLAWVLVGTQLLTPAALAQAMLPEITRSGADSSVDKTDQPEAEWLASRAS
CCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
SLGSLLQEGNISDFAKNQIQALPQTIANDGITSGIKHWLPEAQFRGGITLEDASKYRSAE
HHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHCCCEEEECHHHHCCCC
ADLLIPLYQSTSSILFGQLGLRDHDNNSFNGRFFVNTGIGWRQDVGDWLLGINSFLDADV
CCEEEEECCCCCCEEEEECCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCC
RYDHLRGSLGVELFRDSMSLAGNWYFPLSDWKASKVQPLHDERPATGIDVRLKGALPSLP
CHHHHCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCC
WFGAELAFEQYFGDKVDILGNDSLTRDPAAFTGAITWKPVPLVEIKAGYKDAGSSGSQTE
CCCHHHHHHHHCCCEEEEECCCCCCCCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCCC
AGLNLNYTFGVPLRAQLDPSQVRPASNTTNRTAFVDRNYNIVMEYREQASRIRVYASPVN
CCEEEEEEECCCEEECCCHHHCCCCCCCCCCEEEEECCCEEEEEEHHCCCEEEEEEECCC
GQSGDTVTLSATINSRYPVERIEWTGDAELIGGLQQQGNVNSGLRLPDLSLDVTENKEYS
CCCCCEEEEEEEECCCCCCCEEEECCCHHHHHCHHHCCCCCCCCCCCCCEEEEECCCCEE
LYLKVTDSRGNSVTSERIPVTVSINPESFTPYLNVLHDEVRREEGKFVIPSPTVNDDNGS
EEEEEECCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCEECCCCCCCCCCCC
IIEWHYVRVRSKDEWKSLKPENVEYSTHSPGLSFKSLGGEERDGQWIEKVQLVVKDPTAR
EEEEEEEEECCCHHHHCCCCCCCEECCCCCCCCHHHCCCCCCCCHHHHEEEEEEECCCCE
MTLAAMELNISATGPGGTHPVNGTIRMTPVMNLTDKVSSVQILFTAGTEELNGSTNAPVV
EEEEEEEEEEEECCCCCCCCCCCEEEEEEECCCCCCCCEEEEEEEECCHHCCCCCCCCEE
GSTLQAKTTCDTDKDCSSLFRYQWEISPDGNRWYDVPGATGQSWLMPAVMDGHSLQNKQV
CCCEEECCCCCCCHHHHHHEEEEEEECCCCCEEEECCCCCCCCCCCHHHCCCCCCCCCEE
RVRVVSENVPTH
EEEEECCCCCCC
>Mature Secondary Structure
MKLTPTPLARWLAWVLVGTQLLTPAALAQAMLPEITRSGADSSVDKTDQPEAEWLASRAS
CCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
SLGSLLQEGNISDFAKNQIQALPQTIANDGITSGIKHWLPEAQFRGGITLEDASKYRSAE
HHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHCCCEEEECHHHHCCCC
ADLLIPLYQSTSSILFGQLGLRDHDNNSFNGRFFVNTGIGWRQDVGDWLLGINSFLDADV
CCEEEEECCCCCCEEEEECCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCC
RYDHLRGSLGVELFRDSMSLAGNWYFPLSDWKASKVQPLHDERPATGIDVRLKGALPSLP
CHHHHCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCC
WFGAELAFEQYFGDKVDILGNDSLTRDPAAFTGAITWKPVPLVEIKAGYKDAGSSGSQTE
CCCHHHHHHHHCCCEEEEECCCCCCCCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCCC
AGLNLNYTFGVPLRAQLDPSQVRPASNTTNRTAFVDRNYNIVMEYREQASRIRVYASPVN
CCEEEEEEECCCEEECCCHHHCCCCCCCCCCEEEEECCCEEEEEEHHCCCEEEEEEECCC
GQSGDTVTLSATINSRYPVERIEWTGDAELIGGLQQQGNVNSGLRLPDLSLDVTENKEYS
CCCCCEEEEEEEECCCCCCCEEEECCCHHHHHCHHHCCCCCCCCCCCCCEEEEECCCCEE
LYLKVTDSRGNSVTSERIPVTVSINPESFTPYLNVLHDEVRREEGKFVIPSPTVNDDNGS
EEEEEECCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCEECCCCCCCCCCCC
IIEWHYVRVRSKDEWKSLKPENVEYSTHSPGLSFKSLGGEERDGQWIEKVQLVVKDPTAR
EEEEEEEEECCCHHHHCCCCCCCEECCCCCCCCHHHCCCCCCCCHHHHEEEEEEECCCCE
MTLAAMELNISATGPGGTHPVNGTIRMTPVMNLTDKVSSVQILFTAGTEELNGSTNAPVV
EEEEEEEEEEEECCCCCCCCCCCEEEEEEECCCCCCCCEEEEEEEECCHHCCCCCCCCEE
GSTLQAKTTCDTDKDCSSLFRYQWEISPDGNRWYDVPGATGQSWLMPAVMDGHSLQNKQV
CCCEEECCCCCCCHHHHHHEEEEEEECCCCCEEEECCCCCCCCCCCHHHCCCCCCCCCEE
RVRVVSENVPTH
EEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3304658; 1693333; 10514372 [H]