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The map label for this gene is gst [C]

Identifier: 218548922

GI number: 218548922

Start: 1599987

End: 1600583

Strand: Reverse

Name: gst [C]

Synonym: EFER_1568

Alternate gene names: 218548922

Gene position: 1600583-1599987 (Counterclockwise)

Preceding gene: 218548924

Following gene: 218548919

Centisome position: 34.88

GC content: 38.02

Gene sequence:

>597_bases
ATGAAGATTTATACTTATCCTAAAAGTAGATCTCTGAGAGTACTTTGGGTACTTGAAGAAATTGGAGTAACTTACGAGGC
CATTAAAGTTGATCTTTTCAATCGCGGTTCTAACGTGAAATCACCGCATCCTCTTGGAAAAGTTCCTTTTTTGATAGACG
AAGAAGTATCAATAAGTGAGACCCTTGCCATATGTATCTACCTTTGTGAAAAACATCAAAATTTCACTCTTTATCCCGCA
AACTTGGGTGAAAAAGCCTCTGTTAATTCTTGGTTGAGCTTTAGCCTCACCGATTTAGAAGCACCTGTATGGGGGTTGCT
CAAACACATCATTTTTACTCCAGAAAATCAACGCTCCACAACCTTAATGAATTACTTTAGAGAAGAAGCAGACAAGGTTA
TCTCCCAAATTCACTTCAACTCAGCTCATACTTGGATCGCAGGTAATTATTTTACTCTGGCTGACATTTTTCTCTCTCAC
ACATTGCAATGGGCAAAAGTGTGTGGATTAGACATCAACGCAGAAACTAACAGCTATATAGTTAGAACAATGAGCCGACC
CGCATTCGTGAAAGCTCAAGAAAGAAATAATTTTTAA

Upstream 100 bases:

>100_bases
ATGACATGTCCGCGCTACAGTCTCACCACAGCGATCACTGCTTTCAAAGGTTGAGACTCATGGCGGCATACAAGTTGGTA
AATAAACAAAAGGGTTTGAA

Downstream 100 bases:

>100_bases
TCAGAGTTGTAATCTGTATTGGAATGTATGCATGGTTGAAGTCCAAAAGTCCGCTGCTGGCACAAAGCGGACTTTTCAGC
TTTGCCCTGCCCCGGATATC

Product: glutathione S-transferase family protein

Products: HX; R-S-Glutathione; S-(2,4-dinitrophenyl)glutathione [C]

Alternate protein names: Glutathione S-Transferase; Glutathione S-Transferase Family Protein; Glutathione S-Transferase Domain Protein; Glutathione S-Transferase-Like Protein; Glutathione S-Transferase N-Terminal Domain Protein; Glutathione S-Transferase-Like; Glutathione S-Transferase Protein; Glutathione S-Transferase III; Glutathione Transferase; Glutathione S-Transferase N-Terminal Domain; Glutathione S-Transferase Like Protein; GSH-Dependent Dehydroascorbate Reductase; Glutathione S-Transferase C-Terminal Domain Protein; Glutathione S-Transferase Domain

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MKIYTYPKSRSLRVLWVLEEIGVTYEAIKVDLFNRGSNVKSPHPLGKVPFLIDEEVSISETLAICIYLCEKHQNFTLYPA
NLGEKASVNSWLSFSLTDLEAPVWGLLKHIIFTPENQRSTTLMNYFREEADKVISQIHFNSAHTWIAGNYFTLADIFLSH
TLQWAKVCGLDINAETNSYIVRTMSRPAFVKAQERNNF

Sequences:

>Translated_198_residues
MKIYTYPKSRSLRVLWVLEEIGVTYEAIKVDLFNRGSNVKSPHPLGKVPFLIDEEVSISETLAICIYLCEKHQNFTLYPA
NLGEKASVNSWLSFSLTDLEAPVWGLLKHIIFTPENQRSTTLMNYFREEADKVISQIHFNSAHTWIAGNYFTLADIFLSH
TLQWAKVCGLDINAETNSYIVRTMSRPAFVKAQERNNF
>Mature_198_residues
MKIYTYPKSRSLRVLWVLEEIGVTYEAIKVDLFNRGSNVKSPHPLGKVPFLIDEEVSISETLAICIYLCEKHQNFTLYPA
NLGEKASVNSWLSFSLTDLEAPVWGLLKHIIFTPENQRSTTLMNYFREEADKVISQIHFNSAHTWIAGNYFTLADIFLSH
TLQWAKVCGLDINAETNSYIVRTMSRPAFVKAQERNNF

Specific function: Conjugation Of Reduced Glutathione To A Wide Number Of Exogenous And Endogenous Hydrophobic Electrophiles. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.5.1.18 [C]

Molecular weight: Translated: 22738; Mature: 22738

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIYTYPKSRSLRVLWVLEEIGVTYEAIKVDLFNRGSNVKSPHPLGKVPFLIDEEVSISE
CEEEECCCCCCEEEEEEEHHHCCEEEEEEEEEECCCCCCCCCCCCCCCCEEECCCCCHHH
TLAICIYLCEKHQNFTLYPANLGEKASVNSWLSFSLTDLEAPVWGLLKHIIFTPENQRST
HHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCHH
TLMNYFREEADKVISQIHFNSAHTWIAGNYFTLADIFLSHTLQWAKVCGLDINAETNSYI
HHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEE
VRTMSRPAFVKAQERNNF
EEECCCCCEEEECCCCCC
>Mature Secondary Structure
MKIYTYPKSRSLRVLWVLEEIGVTYEAIKVDLFNRGSNVKSPHPLGKVPFLIDEEVSISE
CEEEECCCCCCEEEEEEEHHHCCEEEEEEEEEECCCCCCCCCCCCCCCCEEECCCCCHHH
TLAICIYLCEKHQNFTLYPANLGEKASVNSWLSFSLTDLEAPVWGLLKHIIFTPENQRST
HHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCHH
TLMNYFREEADKVISQIHFNSAHTWIAGNYFTLADIFLSHTLQWAKVCGLDINAETNSYI
HHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEE
VRTMSRPAFVKAQERNNF
EEECCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: RX; Glutathione; 1-chloro-2,4-dinitrobenzene; reduced glutathione [C]

Specific reaction: RX + Glutathione = HX + R-S-Glutathione 1-chloro-2,4-dinitrobenzene + reduced glutathione = S-(2,4-dinitrophenyl)glutathione [C]

General reaction: Aryl group transfer [C]

Inhibitor: Cd2+; CibacronBlue; Co2+; Cu2+; Hematin; Hg2+; Ni2+; Sulfophthaleins; Tributyl tinacetate; Triethyl tinbromide; Zn2+ [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA