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The map label for this gene is lsrD [H]

Identifier: 218548917

GI number: 218548917

Start: 1593367

End: 1594359

Strand: Reverse

Name: lsrD [H]

Synonym: EFER_1562

Alternate gene names: 218548917

Gene position: 1594359-1593367 (Counterclockwise)

Preceding gene: 218548918

Following gene: 218548916

Centisome position: 34.75

GC content: 52.57

Gene sequence:

>993_bases
ATGCGTATTCGCTACGGTTGGGAACTGGCCCTTGCCGCATTACTCGTTATTGAGATTGTCGCATTTGGCGCAGTAAATCC
GCGAATGTTAGATCTCAATATGCTGTTGTTTAGCACCAGTGATTTTATCTGTATTGGCATTGTCGCCCTACCGCTGACGA
TGGTGATTGTCAGTGGCGGGATCGATATTTCGTTTGGTTCGACTATCGGCCTGTGCGCCATCGCATTGGGTGTGTTGTTT
CAAGGCGGCGTGCCAATGCCGCTGGCGATTATCCTGACGTTACTGCTCGGCGCATTGTGCGGTCTGATTAACGCCGGATT
AATTATCTATACCAAAGTTAACCCGCTGGTGATTACGCTTGGCACGCTGTATCTGTTTGCTGGAAGCGCCCTGCTGCTTT
CCGGGATGGCTGGGGCTACGGGGTACGAAGGTATTGGTGGATTCCCGATGGCGTTTACAGATTTCGCTAATCTGGATGTG
CTGGGGCTTCCCGTTCCGCTGATTATCTTTCTGATATGTCTCATCGTTTTCTGGCTGTGGCTGCATAAAACCCATGCCGG
ACGTAATGTGTTTTTGATTGGACAAAGCCCGCGCGTGGCGCTTTATAGCGCGATTCCGGTTAACCGCACCTTATGTGCAC
TCTATGCCATGACGGGGCTGGCGTCTGCGGTCGCCGCCGTGCTGCTGGTTTCGTATTTTGGTTCTGCACGCTCCGATCTC
GGTGCGTCGTTTTTGATGCCCGCCATCACCGCCGTGGTGCTTGGTGGTGCCAATATTTATGGTGGTTCCGGTTCGATTAT
CGGCACTGCCATTGCGGTTTTATTAGTGGGATATTTGCAACAAGGTTTGCAAATGGCAGGAGTGCCAAATCAGGTGTCCA
GCGCCCTTTCCGGCGCGCTGCTTATCGTCGTTGTCGTAGGTCGTTCCGTTAGCCTGCATCGCCAGCAAATTAAAGAGTGG
CTGGCGCGCCGGGCCAATAACACATTGCCATAA

Upstream 100 bases:

>100_bases
CGCTGGAACGTAATCTGCGGCGGCAAAAATATGCCCGCTTTATGACGCCACCGGCATCCGTTAAACCCGATTCGTCAGGA
AAAAAACGGGAGGCCGCGTA

Downstream 100 bases:

>100_bases
AGGATATCTTCATGACACTTCATCGCCTTAAGAAAATCGCCTTACTTAGTGCCCTTGGCATTGCCGCAATTTCTGTGAAT
GTACAGGCCGCCGAGCGTAT

Product: AI2 ABC transporter membrane protein

Products: NA

Alternate protein names: AI-2 import system permease protein lsrD [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MRIRYGWELALAALLVIEIVAFGAVNPRMLDLNMLLFSTSDFICIGIVALPLTMVIVSGGIDISFGSTIGLCAIALGVLF
QGGVPMPLAIILTLLLGALCGLINAGLIIYTKVNPLVITLGTLYLFAGSALLLSGMAGATGYEGIGGFPMAFTDFANLDV
LGLPVPLIIFLICLIVFWLWLHKTHAGRNVFLIGQSPRVALYSAIPVNRTLCALYAMTGLASAVAAVLLVSYFGSARSDL
GASFLMPAITAVVLGGANIYGGSGSIIGTAIAVLLVGYLQQGLQMAGVPNQVSSALSGALLIVVVVGRSVSLHRQQIKEW
LARRANNTLP

Sequences:

>Translated_330_residues
MRIRYGWELALAALLVIEIVAFGAVNPRMLDLNMLLFSTSDFICIGIVALPLTMVIVSGGIDISFGSTIGLCAIALGVLF
QGGVPMPLAIILTLLLGALCGLINAGLIIYTKVNPLVITLGTLYLFAGSALLLSGMAGATGYEGIGGFPMAFTDFANLDV
LGLPVPLIIFLICLIVFWLWLHKTHAGRNVFLIGQSPRVALYSAIPVNRTLCALYAMTGLASAVAAVLLVSYFGSARSDL
GASFLMPAITAVVLGGANIYGGSGSIIGTAIAVLLVGYLQQGLQMAGVPNQVSSALSGALLIVVVVGRSVSLHRQQIKEW
LARRANNTLP
>Mature_330_residues
MRIRYGWELALAALLVIEIVAFGAVNPRMLDLNMLLFSTSDFICIGIVALPLTMVIVSGGIDISFGSTIGLCAIALGVLF
QGGVPMPLAIILTLLLGALCGLINAGLIIYTKVNPLVITLGTLYLFAGSALLLSGMAGATGYEGIGGFPMAFTDFANLDV
LGLPVPLIIFLICLIVFWLWLHKTHAGRNVFLIGQSPRVALYSAIPVNRTLCALYAMTGLASAVAAVLLVSYFGSARSDL
GASFLMPAITAVVLGGANIYGGSGSIIGTAIAVLLVGYLQQGLQMAGVPNQVSSALSGALLIVVVVGRSVSLHRQQIKEW
LARRANNTLP

Specific function: Part of the ABC transporter complex lsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1172

COG function: function code G; Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787794, Length=330, Percent_Identity=98.4848484848485, Blast_Score=632, Evalue=0.0,
Organism=Escherichia coli, GI1790524, Length=307, Percent_Identity=28.6644951140065, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1788896, Length=318, Percent_Identity=28.9308176100629, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790191, Length=292, Percent_Identity=29.4520547945205, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI145693152, Length=274, Percent_Identity=29.1970802919708, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788471, Length=221, Percent_Identity=32.1266968325792, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1787793, Length=306, Percent_Identity=31.0457516339869, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI145693214, Length=274, Percent_Identity=27.007299270073, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87082395, Length=308, Percent_Identity=26.2987012987013, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789992, Length=133, Percent_Identity=32.3308270676692, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 34417; Mature: 34417

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIRYGWELALAALLVIEIVAFGAVNPRMLDLNMLLFSTSDFICIGIVALPLTMVIVSGG
CCEECHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHECCCCCHHHHHHHHHHHHHHHHCCC
IDISFGSTIGLCAIALGVLFQGGVPMPLAIILTLLLGALCGLINAGLIIYTKVNPLVITL
CEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHH
GTLYLFAGSALLLSGMAGATGYEGIGGFPMAFTDFANLDVLGLPVPLIIFLICLIVFWLW
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCEECCCHHHHHHHHHHHHHHHH
LHKTHAGRNVFLIGQSPRVALYSAIPVNRTLCALYAMTGLASAVAAVLLVSYFGSARSDL
HHHHCCCCEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHC
GASFLMPAITAVVLGGANIYGGSGSIIGTAIAVLLVGYLQQGLQMAGVPNQVSSALSGAL
CHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LIVVVVGRSVSLHRQQIKEWLARRANNTLP
HEEHHHCCCHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MRIRYGWELALAALLVIEIVAFGAVNPRMLDLNMLLFSTSDFICIGIVALPLTMVIVSGG
CCEECHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHECCCCCHHHHHHHHHHHHHHHHCCC
IDISFGSTIGLCAIALGVLFQGGVPMPLAIILTLLLGALCGLINAGLIIYTKVNPLVITL
CEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHH
GTLYLFAGSALLLSGMAGATGYEGIGGFPMAFTDFANLDVLGLPVPLIIFLICLIVFWLW
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCEECCCHHHHHHHHHHHHHHHH
LHKTHAGRNVFLIGQSPRVALYSAIPVNRTLCALYAMTGLASAVAAVLLVSYFGSARSDL
HHHHCCCCEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHC
GASFLMPAITAVVLGGANIYGGSGSIIGTAIAVLLVGYLQQGLQMAGVPNQVSSALSGAL
CHHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
LIVVVVGRSVSLHRQQIKEWLARRANNTLP
HEEHHHCCCHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]