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The map label for this gene is lsrC [H]

Identifier: 218548918

GI number: 218548918

Start: 1594359

End: 1595387

Strand: Reverse

Name: lsrC [H]

Synonym: EFER_1563

Alternate gene names: 218548918

Gene position: 1595387-1594359 (Counterclockwise)

Preceding gene: 218548919

Following gene: 218548917

Centisome position: 34.77

GC content: 53.26

Gene sequence:

>1029_bases
ATGCTGAAGTTTATCCAGAACAACCGTGAAATCACGGCACTGCTGGCGGTGGTGTTGCTGTTTGTATTACCCGGTTTTCT
CGACCGCCAGTATTTAAGTCTGCAAACGCTAACCATGGTTTATAGCAGCGCGCAAATCCTGATCCTGCTGGCAATGGGCG
CGACGCTGGTGATGCTGACACGCAATATTGATGTTTCAGTGGGTTCGATTACCGGAATGTGCGCGGTGCTGTTGGGGATG
TTATTAAACGCAGGATATTCACTGCCTGTTGCCTGTGTCGCGACTTTACTGCTCGGCTTGCTGGCGGGATTTTTCAACGG
CGTATTGGTCGCGTGGCTAAAGATCCCAGCCATTGTTGCCACCCTTGGCACGTTAGGGTTGTACAGAGGCATCATGTTGC
TGTGGACTGGCGGTAAATGGATTGAGGGATTACCCGCTGAACTGAAACAGCTCTCCGCCCCGCTGCTGCTTGGCGTTTCA
GCAATTGGTTGGTTGACGATAATTCTGGTGGCATTTATGGCCTGGCTGCTGGCGAAGACGGCGTTTGGACGCAGTTTTTA
TGCCACCGGCGATAATTTGCAGGGCGCTCGTCAATTGGGTGTTCGTACGGAAGCCATTCGAATTGTGGCATTTTCTTTGA
ATGGCTGCATGGCGGCACTGGCGGGGATTGTGTTTGCTTCACAGATTGGTTTTATCCCCAACCAGACCGGCACAGGGCTT
GAGATGAAAGCGATTGCAGCCTGTGTGTTGGGCGGCATTAGTTTGCTCGGCGGTTCTGGTGCAATTATCGGCGCGGTACT
CGGCGCATGGTTCCTGACGCAGATCGATAGCGTACTGGTGCTGTTGCGCATTCCGGCATGGTGGAATGATTTTATCGCGG
GCCTCGTGCTGCTGGGAGTGCTGGTATTTGATGGACGACTGCGTTGTGCGCTGGAACGTAATCTGCGGCGGCAAAAATAT
GCCCGCTTTATGACGCCACCGGCATCCGTTAAACCCGATTCGTCAGGAAAAAAACGGGAGGCCGCGTAA

Upstream 100 bases:

>100_bases
ATCAGGGCGAAATTGCCCACTCTGCACTGACCGGACGCGATATTAATGTCGAGACCATTATGCGCGTTGCCTTCGGCGAT
AGTCAGCGTCAGGAGGCATC

Downstream 100 bases:

>100_bases
TGCGTATTCGCTACGGTTGGGAACTGGCCCTTGCCGCATTACTCGTTATTGAGATTGTCGCATTTGGCGCAGTAAATCCG
CGAATGTTAGATCTCAATAT

Product: AI2 ABC transporter membrane protein

Products: NA

Alternate protein names: AI-2 import system permease protein lsrC [H]

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MLKFIQNNREITALLAVVLLFVLPGFLDRQYLSLQTLTMVYSSAQILILLAMGATLVMLTRNIDVSVGSITGMCAVLLGM
LLNAGYSLPVACVATLLLGLLAGFFNGVLVAWLKIPAIVATLGTLGLYRGIMLLWTGGKWIEGLPAELKQLSAPLLLGVS
AIGWLTIILVAFMAWLLAKTAFGRSFYATGDNLQGARQLGVRTEAIRIVAFSLNGCMAALAGIVFASQIGFIPNQTGTGL
EMKAIAACVLGGISLLGGSGAIIGAVLGAWFLTQIDSVLVLLRIPAWWNDFIAGLVLLGVLVFDGRLRCALERNLRRQKY
ARFMTPPASVKPDSSGKKREAA

Sequences:

>Translated_342_residues
MLKFIQNNREITALLAVVLLFVLPGFLDRQYLSLQTLTMVYSSAQILILLAMGATLVMLTRNIDVSVGSITGMCAVLLGM
LLNAGYSLPVACVATLLLGLLAGFFNGVLVAWLKIPAIVATLGTLGLYRGIMLLWTGGKWIEGLPAELKQLSAPLLLGVS
AIGWLTIILVAFMAWLLAKTAFGRSFYATGDNLQGARQLGVRTEAIRIVAFSLNGCMAALAGIVFASQIGFIPNQTGTGL
EMKAIAACVLGGISLLGGSGAIIGAVLGAWFLTQIDSVLVLLRIPAWWNDFIAGLVLLGVLVFDGRLRCALERNLRRQKY
ARFMTPPASVKPDSSGKKREAA
>Mature_342_residues
MLKFIQNNREITALLAVVLLFVLPGFLDRQYLSLQTLTMVYSSAQILILLAMGATLVMLTRNIDVSVGSITGMCAVLLGM
LLNAGYSLPVACVATLLLGLLAGFFNGVLVAWLKIPAIVATLGTLGLYRGIMLLWTGGKWIEGLPAELKQLSAPLLLGVS
AIGWLTIILVAFMAWLLAKTAFGRSFYATGDNLQGARQLGVRTEAIRIVAFSLNGCMAALAGIVFASQIGFIPNQTGTGL
EMKAIAACVLGGISLLGGSGAIIGAVLGAWFLTQIDSVLVLLRIPAWWNDFIAGLVLLGVLVFDGRLRCALERNLRRQKY
ARFMTPPASVKPDSSGKKREAA

Specific function: Part of the ABC transporter complex lsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1172

COG function: function code G; Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787793, Length=342, Percent_Identity=98.8304093567251, Blast_Score=659, Evalue=0.0,
Organism=Escherichia coli, GI1789992, Length=356, Percent_Identity=31.1797752808989, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1788896, Length=303, Percent_Identity=31.3531353135314, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1790191, Length=305, Percent_Identity=31.8032786885246, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI145693152, Length=267, Percent_Identity=34.0823970037453, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1790524, Length=277, Percent_Identity=26.7148014440433, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI145693214, Length=285, Percent_Identity=34.3859649122807, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87082395, Length=321, Percent_Identity=30.2180685358255, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1787794, Length=311, Percent_Identity=31.1897106109325, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1788471, Length=307, Percent_Identity=30.2931596091205, Blast_Score=81, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 36413; Mature: 36413

Theoretical pI: Translated: 10.29; Mature: 10.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKFIQNNREITALLAVVLLFVLPGFLDRQYLSLQTLTMVYSSAQILILLAMGATLVMLT
CCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNIDVSVGSITGMCAVLLGMLLNAGYSLPVACVATLLLGLLAGFFNGVLVAWLKIPAIVA
CCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLGTLGLYRGIMLLWTGGKWIEGLPAELKQLSAPLLLGVSAIGWLTIILVAFMAWLLAKT
HHHHHHHHHHHHEEECCCHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFGRSFYATGDNLQGARQLGVRTEAIRIVAFSLNGCMAALAGIVFASQIGFIPNQTGTGL
HHCCCEECCCCCCCHHHHHCCHHHHHEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCC
EMKAIAACVLGGISLLGGSGAIIGAVLGAWFLTQIDSVLVLLRIPAWWNDFIAGLVLLGV
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LVFDGRLRCALERNLRRQKYARFMTPPASVKPDSSGKKREAA
HHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLKFIQNNREITALLAVVLLFVLPGFLDRQYLSLQTLTMVYSSAQILILLAMGATLVMLT
CCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RNIDVSVGSITGMCAVLLGMLLNAGYSLPVACVATLLLGLLAGFFNGVLVAWLKIPAIVA
CCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLGTLGLYRGIMLLWTGGKWIEGLPAELKQLSAPLLLGVSAIGWLTIILVAFMAWLLAKT
HHHHHHHHHHHHEEECCCHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFGRSFYATGDNLQGARQLGVRTEAIRIVAFSLNGCMAALAGIVFASQIGFIPNQTGTGL
HHCCCEECCCCCCCHHHHHCCHHHHHEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCC
EMKAIAACVLGGISLLGGSGAIIGAVLGAWFLTQIDSVLVLLRIPAWWNDFIAGLVLLGV
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LVFDGRLRCALERNLRRQKYARFMTPPASVKPDSSGKKREAA
HHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]