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The map label for this gene is pgsA [H]

Identifier: 218548551

GI number: 218548551

Start: 1221688

End: 1222236

Strand: Direct

Name: pgsA [H]

Synonym: EFER_1182

Alternate gene names: 218548551

Gene position: 1221688-1222236 (Clockwise)

Preceding gene: 218548550

Following gene: 218548553

Centisome position: 26.62

GC content: 51.0

Gene sequence:

>549_bases
ATGCAATTTAATATCCCTACGTTGCTCACGCTGTTTCGCGTCATCCTTATCCCATTCTTTGTATTGGTCTTTTATCTCCC
TGTCACCTGGTCGCCATTTGCTGCTGCGCTTATTTTCTGCGTCGCGGCAGTGACCGACTGGTTTGATGGTTTCCTGGCGC
GGCGCTGGAATCAAAGCACCCGTTTCGGGGCGTTTCTTGATCCCGTTGCCGACAAAGTCCTGGTGGCAATTGCAATGGTA
CTGGTTACCGAGCACTACCACAGCTGGTGGGTGACGTTACCGGCAGCAACCATGATTGCGCGTGAAATTATTATTTCTGC
ACTGCGTGAGTGGATGGCGGAACTGGGCAAACGCAGTAGTGTGGCTGTATCCTGGATTGGTAAAGTGAAAACCACGGCAC
AAATGGTAGCGCTGGCATGGCTGTTATGGCGTCCAAACATTTGGGTCGAGTATGCGGGGATTGCATTATTCTTCGTTGCT
GCTGTGCTGACACTGTGGTCAATGTTCCAGTATTTGAACGCTGCGCGAGCAGATTTGCTTGAACAGTGA

Upstream 100 bases:

>100_bases
CGCAAGGTCTGGCAGAAAAGATCTTCTGGTCGTTGAAACATTGAGTCCGCTGTAGCAACATAGGGGTAATTTCTCTGACA
ACAGATAGTTACCCGTCATT

Downstream 100 bases:

>100_bases
TCGTTTCGCCGCAATTTTCAGCAAACGATCATCTGCGGCAAAAAATATCGTTGACTCATCGCGTCAGGTAAGTAGAATGC
AACGCATCGAACGGCGGCAC

Product: phosphatidylglycerophosphate synthetase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MQFNIPTLLTLFRVILIPFFVLVFYLPVTWSPFAAALIFCVAAVTDWFDGFLARRWNQSTRFGAFLDPVADKVLVAIAMV
LVTEHYHSWWVTLPAATMIAREIIISALREWMAELGKRSSVAVSWIGKVKTTAQMVALAWLLWRPNIWVEYAGIALFFVA
AVLTLWSMFQYLNAARADLLEQ

Sequences:

>Translated_182_residues
MQFNIPTLLTLFRVILIPFFVLVFYLPVTWSPFAAALIFCVAAVTDWFDGFLARRWNQSTRFGAFLDPVADKVLVAIAMV
LVTEHYHSWWVTLPAATMIAREIIISALREWMAELGKRSSVAVSWIGKVKTTAQMVALAWLLWRPNIWVEYAGIALFFVA
AVLTLWSMFQYLNAARADLLEQ
>Mature_182_residues
MQFNIPTLLTLFRVILIPFFVLVFYLPVTWSPFAAALIFCVAAVTDWFDGFLARRWNQSTRFGAFLDPVADKVLVAIAMV
LVTEHYHSWWVTLPAATMIAREIIISALREWMAELGKRSSVAVSWIGKVKTTAQMVALAWLLWRPNIWVEYAGIALFFVA
AVLTLWSMFQYLNAARADLLEQ

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=182, Percent_Identity=98.3516483516484, Blast_Score=356, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 20776; Mature: 20776

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFNIPTLLTLFRVILIPFFVLVFYLPVTWSPFAAALIFCVAAVTDWFDGFLARRWNQST
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RFGAFLDPVADKVLVAIAMVLVTEHYHSWWVTLPAATMIAREIIISALREWMAELGKRSS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
VAVSWIGKVKTTAQMVALAWLLWRPNIWVEYAGIALFFVAAVLTLWSMFQYLNAARADLL
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
EQ
CC
>Mature Secondary Structure
MQFNIPTLLTLFRVILIPFFVLVFYLPVTWSPFAAALIFCVAAVTDWFDGFLARRWNQST
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
RFGAFLDPVADKVLVAIAMVLVTEHYHSWWVTLPAATMIAREIIISALREWMAELGKRSS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
VAVSWIGKVKTTAQMVALAWLLWRPNIWVEYAGIALFFVAAVLTLWSMFQYLNAARADLL
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
EQ
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]